scholarly journals Applications of Polymeric Composites in Bone Tissue Engineering and Jawbone Regeneration

Polymers ◽  
2021 ◽  
Vol 13 (19) ◽  
pp. 3429
Author(s):  
Oscar Fraile-Martínez ◽  
Cielo García-Montero ◽  
Alejandro Coca ◽  
Miguel Angel Álvarez-Mon ◽  
Jorge Monserrat ◽  
...  

Polymer-based composites are a group of biomaterials that exert synergic and combined activity. There are multiple reported uses of these composites in multiple biomedical areas, such as drug carriers, in wound dressings, and, more prominently, in tissue engineering and regenerative medicine. Bone grafting is a promising field in the use of polymeric composites, as this is the second most frequently transplanted organ in the United States. Advances in novel biomaterials, such as polymeric composites, will undoubtedly be of great aid in bone tissue engineering and regeneration. In this paper, a general view of bone structure and polymeric composites will be given, discussing the potential role of these components in bone tissue. Moreover, the most relevant jawbone and maxillofacial applications of polymeric composites will be revised in this article, collecting the main knowledge about this topic and emphasizing the need of further clinical studies in humans.

Polymers ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 647
Author(s):  
Mohamed Saiful Firdaus Hussin ◽  
Aludin Mohd Serah ◽  
Khairul Azri Azlan ◽  
Hasan Zuhudi Abdullah ◽  
Maizlinda Izwana Idris ◽  
...  

Collecting information from previous investigations and expressing it in a scientometrics study can be a priceless guide to getting a complete overview of a specific research area. The aim of this study is to explore the interrelated connection between alginate, gelatine, and hydroxyapatite within the scope of bone tissue and scaffold. A review of traditional literature with data mining procedures using bibliometric analyses was considered to identify the evolution of the selected research area between 2009 and 2019. Bibliometric methods and knowledge visualization technologies were implemented to investigate diverse publications based on the following indicators: year of publication, document type, language, country, institution, author, journal, keyword, and number of citations. An analysis using a bibliometric study found that 7446 papers were located with the keywords “bone tissue” and “scaffold”, and 1767 (alginate), 185 (gelatine), 5658 (hydroxyapatite) papers with those specific sub keywords. The number of publications that relate to “tissue engineering” and bone more than doubled between 2009 (1352) and 2019 (2839). China, the United States and India are the most productive countries, while Sichuan University and the Chinese Academy of Science from China are the most important institutions related to bone tissue scaffold. Materials Science and Engineering C is the most productive journal, followed by the Journal of Biomedical Materials Research Part A. This paper is a starting point, providing the first bibliometric analysis study of bone tissue and scaffold considering alginate, gelatine and hydroxyapatite. A bibliometric analysis would greatly assist in giving a scientific insight to support desired future research work, not only associated with bone tissue engineering applications. It is expected that the analysis of alginate, gelatine and hydroxyapatite in terms of 3D bioprinting, clinical outcomes, scaffold architecture, and the regenerative medicine approach will enhance the research into bone tissue engineering in the near future. Continued studies into these research fields are highly recommended.


2019 ◽  
Vol 10 (1) ◽  
pp. 16 ◽  
Author(s):  
Baboucarr Lowe ◽  
Mark P. Ottensmeyer ◽  
Chun Xu ◽  
Yan He ◽  
Qingsong Ye ◽  
...  

The conventional applicability of biomaterials in the field of bone tissue engineering takes into consideration several key parameters to achieve desired results for prospective translational use. Hence, several engineering strategies have been developed to model in the regenerative parameters of different forms of biomaterials, including bioactive glass and β-tricalcium phosphate. This review examines the different ways these two materials are transformed and assembled with other regenerative factors to improve their application for bone tissue engineering. We discuss the role of the engineering strategy used and the regenerative responses and mechanisms associated with them.


2011 ◽  
Vol 17 (5) ◽  
pp. 331-347 ◽  
Author(s):  
Ana Rita Costa-Pinto ◽  
Rui L. Reis ◽  
Nuno M. Neves

2014 ◽  
Vol 9 (10) ◽  
pp. 1133-1149 ◽  
Author(s):  
Rainer Detsch ◽  
Aldo R. Boccaccini

Nanomaterials ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 2019 ◽  
Author(s):  
Pawan Kumar ◽  
Meenu Saini ◽  
Brijnandan S. Dehiya ◽  
Anil Sindhu ◽  
Vinod Kumar ◽  
...  

One of the most important ideas ever produced by the application of materials science to the medical field is the notion of biomaterials. The nanostructured biomaterials play a crucial role in the development of new treatment strategies including not only the replacement of tissues and organs, but also repair and regeneration. They are designed to interact with damaged or injured tissues to induce regeneration, or as a forest for the production of laboratory tissues, so they must be micro-environmentally sensitive. The existing materials have many limitations, including impaired cell attachment, proliferation, and toxicity. Nanotechnology may open new avenues to bone tissue engineering by forming new assemblies similar in size and shape to the existing hierarchical bone structure. Organic and inorganic nanobiomaterials are increasingly used for bone tissue engineering applications because they may allow to overcome some of the current restrictions entailed by bone regeneration methods. This review covers the applications of different organic and inorganic nanobiomaterials in the field of hard tissue engineering.


RSC Advances ◽  
2013 ◽  
Vol 3 (28) ◽  
pp. 11073 ◽  
Author(s):  
Jaba Mitra ◽  
Garima Tripathi ◽  
Ashutosh Sharma ◽  
Bikramjit Basu

Author(s):  
Zhan Jing ◽  
Zhihui Liang ◽  
Liang Yang ◽  
Wenyan Du ◽  
Tao Yu ◽  
...  

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