scholarly journals Highly Sustainable and Completely Amorphous Hierarchical Ceramide Microcapsules for Potential Epidermal Barrier

Polymers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2166
Author(s):  
Joonsik Yoon ◽  
Minjoo Noh ◽  
Jun Bae Lee ◽  
Jun Hyup Lee
Keyword(s):  
Self Assembly ◽  
In Situ Polymerization ◽  
Bioactive Lipids ◽  
Epidermal Barrier ◽  
Long Term Stability ◽  
Packing Structure ◽  
Packing Parameter ◽  
Encapsulation Process ◽  
Main Component

As a main component of the stratum corneum, ceramides can construct protective lamellae to provide an epidermal barrier against dehydration or external microorganisms. However, as ceramide molecules can easily form the isolated crystalline phase through self-assembly due to the amphipathic nature of bioactive lipids, the effective incorporation of ceramides into liquid media is the remaining issue for controlled release. Here, we report an unprecedented effective strategy to fabricate a completely amorphous and highly sustainable hierarchical ceramide polymer microcapsule for promising epidermal barrier by using the interpenetrating and cooperative self-construction of conical amphiphiles with a different critical packing parameter. The self-constructed amorphous architecture of ceramides in polymer microcapsule is achieved by the facile doping of conical amphiphiles and subsequent in situ polymerization of shell polymer in the core-shell geometry. It is experimentally revealed that an irregular cooperative packing structure formed by adaptive hydrophobic–hydrophilic interactions of cylindrical ceramides and conical amphiphiles in the confined microcapsule geometry enables a completely amorphous morphology of ceramides to be realized during the spontaneous encapsulation process. Furthermore, this elegant approach affords a highly dispersible and uniform hierarchical amorphous ceramide microcapsule with a greatly enhanced long-term stability compared to conventional crystalline ceramides.

scholarly journals Bioinspired nano-ordered liquid membrane for precise molecular separation

2020 ◽  
Author(s):  
Haozhen Dou ◽  
Mi Xu ◽  
Baoyu Wang ◽  
Zhen Zhang ◽  
Guobin Wen ◽  
...  
Keyword(s):  
Self Assembly ◽  
High Performance ◽  
Liquid Membrane ◽  
Three Dimensional ◽  
Cellular Membrane ◽  
Liquid Structure ◽  
Long Term Stability ◽  
Separation Membranes ◽  
Molecular Separation

Abstract Cellular membranes provide ideal archetypes for molecule or ion separations with sub-angstrom scale precision, which are featured with both extremely high permeability and selectivity due to the well-defined membrane protein channels. However, the development of bioinspired membranes with artificial channels for sub-angstrom scale ethylene/ethane (0.416 nm / 0.443 nm) separation remains an uncharted territory and a significant challenge. Herein, a bioinspired nano-ordered liquid membrane is constructed by a facile ion/molecule self-assembly strategy for highly efficient ethylene/ethane separation, which mimics the structure of cellular membrane elegantly and possesses plenty of three-dimensional (3D) nanochannels. The elaborate regulation of non-covalent interactions by optimizing the ion/molecule compositions within membrane confers the nano-ordered liquid structure with interpenetrating and bi-continuous apolar domains and polar domains, which results in the formation of regular carrier wires and enormous 3D interconnected ethylene transport nanochannels. By virtue of these 3D nanochannels, the bioinspired nano-ordered liquid membrane manifests simultaneously super-high selectivity, excellent permeance and long-term stability, which exceeds previously reported ethylene/ethane separation membranes. This methodology in this work for construction of bioinspired membrane with tunable 3D nanochannels through ion/molecule self-assembly will enlighten the design and development of high-performance separation membranes for angstrom/sub-angstrom scale ion or molecule separations.

CMOS Compatible Wafer-Scale Encapsulation MEMS Resonators

2007 ◽  
Author(s):  
Bongsang Kim ◽  
Matthew A. Hopcroft ◽  
Renata Melamud ◽  
Chandra M. Jha ◽  
Manu Agarwal ◽  
...  
Keyword(s):  
Quality Factors ◽  
Long Term Stability ◽  
Mems Resonators ◽  
Temperature Coefficient Of Frequency ◽  
Encapsulation Process ◽  
Cmos Compatible ◽  
Ppm Level ◽  
Sealing Layer ◽  
Reduced Temperature

A unique MEMS encapsulation process on the use of epipolysilicon as a packaging and sealing layer is demonstrated. This process provides a very clean and stable environment for MEMS, is compatible with CMOS integration, and can be carried out in a conventional CMOS facility with standard tools. Silicon resonators fabricated inside the ‘epi-seal’ encapsulation showed quality factors over 10,000 and commercial level long-term stability (ppm level drift for over 1 year of operation). In addition, several modifications and improvements, such as Si-SiO2 composite resonators for reduced temperature coefficient of frequency and thermal isolated anchors for direct temperature control were successfully added to this process for improvements in resonator stability over temperature.

Polyaniline/nano-in2O3 Composites Used as a Sensitive Material to NH3

2011 ◽  
Vol 239-242 ◽  
pp. 322-327 ◽  
Author(s):  
Ying Nan Xie ◽  
Zheng Hai Shi ◽  
Jian Lian Liu
Keyword(s):  
In Situ Polymerization ◽  
Average Diameter ◽  
Environmental Stability ◽  
Sensitive Material ◽  
Long Term Stability ◽  
Degree Of Crystallization ◽  
High Degree ◽  
Sulphosalicylic Acid

In presence of nano-In2O3 which were synthesised via a reverse microemulsion, Polyaniline/nano-In2O3 composites were prepared by in-situ polymerization of aniline in 5-sulphosalicylic acid(SSA) aqueous solution. They were characterized by means of TEM, XRD and FTIR.. TEM and XRD showed that the average diameter of In2O3 particles was 15nm with a narrow size distribution and with a high degree of crystallization. The FTIR suggested that the structure of PAn-SSA was not be changed by the mixture of In2O3. Sensitivity of the composites to 100~1000ppm NH3 were studied, the results reveal that polyaniline/nano-In2O3 composites have short response time and good reversibility, the gas sensitive of composites to NH3 under 300ppm increased linearly with the increasing concentration of NH3 and decreased with the increasing of In2O3 concentration. Long-term stability of polyaniline/nano-In2O3 composites were also investagated, it can be concluded that the organic-inorganic hybrid materials have better environmental stability.

scholarly journals A Novel, Nontoxic and Scalable Process to Produce Lipidic Vehicles

Materials ◽  
2020 ◽  
Vol 13 (21) ◽  
pp. 5035
Author(s):  
Nikolaos Naziris ◽  
Natassa Pippa ◽  
Costas Demetzos
Keyword(s):  
Self Assembly ◽  
Room Temperature ◽  
Low Cost ◽  
Scale Up ◽  
Bioactive Molecules ◽  
Second Step ◽  
Long Term Stability ◽  
Prior Art ◽  
Good Homogeneity

Lipidic vehicles are novel industrial products, utilized as components for pharmaceutical, cosmeceutical and nutraceutical formulations. The present study concerns a newly invented method to produce lipidic vehicles in the nanoscale that is simple, nontoxic, versatile, time-efficient, low-cost and easy to scale up. The process is a modification of the heating method (MHM) and comprises (i) providing a mixture of an amphiphilic lipid and a charged lipid and/or a fluidity regulator in a liquid medium composed of water and a liquid polyol, (ii) stirring and heating the mixture in two heating steps, wherein the temperature of the second step is higher than the temperature of the first step and (iii) allowing the mixture to cool down to room temperature. The process leads to the self-assembly of nanoparticles of small size and good homogeneity, compared with conventional approaches that require additional size reduction steps. In addition, the incorporation of bioactive molecules, such as drugs, inside the nanoparticles is possible, while lyophilization of the products provides long-term stability. Most importantly, the absence of toxic solvents and the simplicity guarantee the safety and scalability of the process, distinguishing it from most prior art processes to produce lipidic vehicles.

Facile fabrication of a robust and corrosion resistant superhydrophobic aluminum alloy surface by a novel method

RSC Advances ◽  
2014 ◽  
Vol 4 (98) ◽  
pp. 55556-55564 ◽  
Author(s):  
Cansen Liu ◽  
Fenghua Su ◽  
Jizhao Liang
Keyword(s):  
Self Assembly ◽  
Superhydrophobic Surface ◽  
Assembly Process ◽  
Corrosion Resistant ◽  
Mechanical Abrasion ◽  
Long Term Stability ◽  
Facile Fabrication ◽  
Novel Method ◽  
Aluminum Alloy Surface

A robust superhydrophobic surface with excellent mechanical abrasion and corrosion resistance, self-cleaning ability as well as long-term stability is fabricated by a novel anodic oxidation and self-assembly process.

Ultra-stable two-dimensional MoS2 solution for highly efficient organic solar cells

RSC Advances ◽  
2014 ◽  
Vol 4 (62) ◽  
pp. 32744-32748 ◽  
Author(s):  
Wenqing Liu ◽  
Xi Yang ◽  
Yingying Zhang ◽  
Mingsheng Xu ◽  
Hongzheng Chen
Keyword(s):  
Solar Cell ◽  
Organic Solar Cells ◽  
Self Assembly ◽  
High Performance ◽  
Two Dimensional ◽  
Long Term Stability ◽  
Solar Cell Fabrication ◽  
Cell Fabrication ◽  
Assembly Procedure

A simple self-assembly procedure was developed for preparing a solution of 2D exfoliated MoS2 sheets with very long-term stability suitable for high-performance solar cell fabrication.

Multilayered vitamin C nanoliposomes by self-assembly of alginate and chitosan: Long-term stability and feasibility application in mandarin juice

LWT ◽  
2017 ◽  
Vol 75 ◽  
pp. 608-615 ◽  
Author(s):  
Weilin Liu ◽  
Mengmeng Tian ◽  
Youyu Kong ◽  
Junmeng Lu ◽  
Na Li ◽  
...  
Keyword(s):  
Vitamin C ◽  
Self Assembly ◽  
Term Stability ◽  
Long Term Stability ◽  
Mandarin Juice

Self‐Assembly of Hybrid Oxidant POM@Cu‐BTC for Enhanced Efficiency and Long‐Term Stability of Perovskite Solar Cells

2019 ◽  
Vol 131 (49) ◽  
pp. 17774-17779
Author(s):  
Yayu Dong ◽  
Jian Zhang ◽  
Yulin Yang ◽  
Lele Qiu ◽  
Debin Xia ◽  
...  
Keyword(s):  
Solar Cells ◽  
Self Assembly ◽  
Perovskite Solar Cells ◽  
Term Stability ◽  
Long Term Stability

Surface-Functionalizing Metal, Metal Oxide and Semiconductor Nanocrystals with a Multi-coordinating Polymer Platform

MRS Advances ◽  
2016 ◽  
Vol 1 (56) ◽  
pp. 3741-3747 ◽  
Author(s):  
Wentao Wang ◽  
Xin Ji ◽  
Anshika Kapur ◽  
Hedi Mattoussi
Keyword(s):  
Self Assembly ◽  
Addition Reaction ◽  
Semiconductor Nanocrystals ◽  
Long Term Stability ◽  
Sensing Platforms ◽  
Metal Metal ◽  
Nucleophilic Addition Reaction ◽  
One Step ◽  
Anchoring Groups

ABSTRACTWe introduce a new set of multifunctional metal-coordinating polymers as ligands for the surface functionalization of three different inorganic nanocrystals: luminescent quantum dots (QDs), magnetic iron oxide nanocrystals and metal gold nanoparticles. The ligand design relies on the introduction of a large but controllable number of anchoring groups, hydrophilic moieties and reactive functionalities all in the same polymer chain, via a one-step nucleophilic addition reaction. Nanocrystals capped with these polymer ligands exhibit long-term stability over a broad range of biological conditions. Furthermore, when zwitterion groups are introduced as hydrophilic blocks, this yields a compact ligand coating that allows conjugation of biomolecules to the nanocrystals via metal-histidine self-assembly. The resulting hydrophilic nanocrystals have been used to develop a few specific sensing platforms targeting soluble iron ions and cysteine.

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