scholarly journals Synthesis and Applications of Molecularly Imprinted Polymers Modified TiO2 Nanomaterials: A Review

Polymers ◽  
2018 ◽  
Vol 10 (11) ◽  
pp. 1248 ◽  
Author(s):  
Lingna Sun ◽  
Jie Guan ◽  
Qin Xu ◽  
Xiaoyu Yang ◽  
Juan Wang ◽  
...  
Keyword(s):  
Mass Transfer ◽  
Titanium Dioxide ◽  
Molecularly Imprinted Polymers ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
The Past ◽  
Potential Applications ◽  
Tio2 Nanomaterials ◽  
Further Development ◽  
Relative Adsorption

Titanium dioxide (TiO2) nanomaterials have caused a widespread concern in the past several decades for their bulk characteristics and potential applications in many different areas. Lately, the combination between molecularly imprinted polymers (MIPs) and TiO2 nanomaterials have been proven to improve the relative adsorption capacity, selectivity and accelerate the rate of mass transfer of analyte which is not possible using TiO2 alone. Considering the unique performance of the MIPs modified TiO2 nanomaterials, this review intends to give an overview of the recent progresses in the development of MIPs modified TiO2 nanomaterials, the potential applications of their tailor-made characteristics. The limitations and challenges in this practically promising nanomaterials have also been raised and summarized. By means of the points raised in this article, we would like to provide some assistance for further development of preparation methodologies and the expansion of some potential applications in the field of MIPs modified TiO2 nanomaterials.

scholarly journals Advances in Molecularly Imprinted Polymers as Drug Delivery Systems

Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3589
Author(s):  
Rui Liu ◽  
Alessandro Poma
Keyword(s):  
Drug Delivery ◽  
Molecularly Imprinted Polymers ◽  
Drug Loading ◽  
Stimuli Responsive ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Drug Delivery Vehicles ◽  
The Past ◽  
Drug Molecules ◽  
Delivery Vehicles

Despite the tremendous efforts made in the past decades, severe side/toxic effects and poor bioavailability still represent the main challenges that hinder the clinical translation of drug molecules. This has turned the attention of investigators towards drug delivery vehicles that provide a localized and controlled drug delivery. Molecularly imprinted polymers (MIPs) as novel and versatile drug delivery vehicles have been widely studied in recent years due to the advantages of selective recognition, enhanced drug loading, sustained release, and robustness in harsh conditions. This review highlights the design and development of strategies undertaken for MIPs used as drug delivery vehicles involving different drug delivery mechanisms, such as rate-programmed, stimuli-responsive and active targeting, published during the course of the past five years.

Insights into the formation, structural properties and performance of RAFT polymerized l-phenylalanine anilide molecularly imprinted polymers

2015 ◽  
Vol 6 (41) ◽  
pp. 7320-7332 ◽  
Author(s):  
Mahadeo R. Halhalli ◽  
Börje Sellergren
Keyword(s):  
Mass Transfer ◽  
Pore Structure ◽  
Radical Polymerization ◽  
Molecularly Imprinted Polymers ◽  
Controlled Radical Polymerization ◽  
Structure Parameters ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
And Performance ◽  
Transfer Properties

The enhanced performance of molecularly imprinted polymers prepared by controlled radical polymerization in terms of affinity, selectivity, capacity and mass transfer properties is shown here to correlate with pore structure parameters in their dry and swollen states.

scholarly journals Development of Water-Compatible Molecularly Imprinted Polymers Based on Functionalized β-Cyclodextrin for Controlled Release of Atropine

Polymers ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 130 ◽  
Author(s):  
Yahui He ◽  
Shaomei Zeng ◽  
A. M. Abd El-Aty ◽  
Ahmet Hacımüftüoğlu ◽  
Woldemariam Kalekristos Yohannes ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Molecularly Imprinted Polymers ◽  
Isotherm Models ◽  
Template Molecule ◽  
Stimuli Responsive ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Potential Applications

Herein, a novel method for molecularly imprinted polymers (MIPs) using methacrylic acid functionalized beta-cyclodextrin (MAA-β-CD) monomer is presented, which was designed as a potential water-compatible composite for the controlled release of atropine (ATP). The molecularly imprinted microspheres with pH-sensitive characteristics were fabricated using thermally-initiated precipitation polymerization, employing ATP as a template molecule. The effects of different compounds and concentrations of cross-linking agents were systematically investigated. Uniform microspheres were obtained when the ratio between ATP, MAA-β-CD, and trimethylolpropane trimethacrylate (TRIM) was 1:4:20 (mol/mol/mol) in polymerization system. The ATP loading equilibrium data was best suited to the Freundlich and Langmuir isotherm models. The in vitro drug release study was assessed under simulated oral administration conditions (pH 1.5 and 7.4). The potential usefulness of MIPs as drug delivery devices are much better than non-molecularly imprinted polymers (NIPs). The study shows that the prepared polymers are a pH stimuli-responsive system, which controlled the release of ATP, indicating the potential applications in the field of drug delivery.

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