scholarly journals Synthesis of μ-ABC Tricyclic Miktoarm Star Polymer via Intramolecular Click Cyclization

Polymers ◽  
2018 ◽  
Vol 10 (8) ◽  
pp. 877 ◽  
Author(s):  
Tomoki Shingu ◽  
Takuya Yamamoto ◽  
Kenji Tajima ◽  
Takuya Isono ◽  
Toshifumi Satoh
Keyword(s):  
Self Assembly ◽  
Diblock Copolymers ◽  
Glycidyl Ether ◽  
Chemical Properties ◽  
Star Polymer ◽  
Synthetic Approach ◽  
Glycidyl Ethers ◽  
Miktoarm Star ◽  
Functional Initiators ◽  
Physical And Chemical

Cyclic polymers exhibit unique physical and chemical properties because of the restricted chain mobility and absence of chain ends. Although many types of homopolymers and diblock copolymers possessing cyclic architectures have been synthesized to date, there are relatively few reports of cyclic triblock terpolymers because of their synthetic difficulties. In this study, a novel synthetic approach for μ-ABC tricyclic miktoarm star polymers involving t-Bu-P4-catalyzed ring-opening polymerization (ROP) of glycidyl ethers and intramolecular copper-catalyzed azido-alkyne cycloaddition (CuAAC) was developed. First, the t-Bu-P4-catalyzed ROP of decyl glycidyl ether, dec-9-enyl glycidyl ether, and 2-(2-(2-methoxyethoxy) ethoxy) ethyl glycidyl ether with the aid of functional initiators and terminators was employed for the preparation of a clickable linear triblock terpolymer precursor possessing three azido and three ethynyl groups at the selected positions. Next, the intramolecular CuAAC of the linear precursor successfully produced the well-defined tricyclic triblock terpolymer with narrow dispersity in a reasonable yield. The present strategy is useful for synthesizing model polymers for studying the topological effects on the triblock terpolymer self-assembly.

scholarly journals Polymeric Drug Delivery System Based on Pluronics for Cancer Treatment

Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3610
Author(s):  
Jialin Yu ◽  
Huayu Qiu ◽  
Shouchun Yin ◽  
Hebin Wang ◽  
Yang Li
Keyword(s):  
Drug Delivery ◽  
Self Assembly ◽  
Drug Delivery Systems ◽  
Tumor Therapy ◽  
Chemical Properties ◽  
Drug Carriers ◽  
Disease Diagnosis ◽  
Delivery Systems ◽  
Polymeric Drug Delivery ◽  
Physical And Chemical

Pluronic polymers (pluronics) are a unique class of synthetic triblock copolymers containing hydrophobic polypropylene oxide (PPO) and hydrophilic polyethylene oxide (PEO) arranged in the PEO-PPO-PEO manner. Due to their excellent biocompatibility and amphiphilic properties, pluronics are an ideal and promising biological material, which is widely used in drug delivery, disease diagnosis, and treatment, among other applications. Through self-assembly or in combination with other materials, pluronics can form nano carriers with different morphologies, representing a kind of multifunctional pharmaceutical excipients. In recent years, the utilization of pluronic-based multi-functional drug carriers in tumor treatment has become widespread, and various responsive drug carriers are designed according to the characteristics of the tumor microenvironment, resulting in major progress in tumor therapy. This review introduces the specific role of pluronic-based polymer drug delivery systems in tumor therapy, focusing on their physical and chemical properties as well as the design aspects of pluronic polymers. Finally, using newer literature reports, this review provides insights into the future potential and challenges posed by different pluronic-based polymer drug delivery systems in tumor therapy.

scholarly journals Expanding the molecular-ruler process through vapor deposition of hexadecanethiol

2017 ◽  
Vol 8 ◽  
pp. 2339-2344 ◽  
Author(s):  
Alexandra M Patron ◽  
Timothy S Hooker ◽  
Daniel F Santavicca ◽  
Corey P Causey ◽  
Thomas J Mullen
Keyword(s):  
Vapor Phase ◽  
Self Assembly ◽  
Chemical Properties ◽  
Solution Deposition ◽  
Precise Control ◽  
Vapor Phase Deposition ◽  
Great Utility ◽  
Complex Architectures ◽  
Molecular Ruler ◽  
Physical And Chemical

The development of methods to produce nanoscale features with tailored chemical functionalities is fundamental for applications such as nanoelectronics and sensor fabrication. The molecular-ruler process shows great utility for this purpose as it combines top-down lithography for the creation of complex architectures over large areas in conjunction with molecular self-assembly, which enables precise control over the physical and chemical properties of small local features. The molecular-ruler process, which most commonly uses mercaptoalkanoic acids and metal ions to generate metal-ligated multilayers, can be employed to produce registered nanogaps between metal features. Expansion of this methodology to include molecules with other chemical functionalities could greatly expand the overall versatility, and thus the utility, of this process. Herein, we explore the use of alkanethiol molecules as the terminating layer of metal-ligated multilayers. During this study, it was discovered that the solution deposition of alkanethiol molecules resulted in low overall surface coverage with features that varied in height. Because features with varied heights are not conducive to the production of uniform nanogaps via the molecular-ruler process, the vapor-phase deposition of alkanethiol molecules was explored. Unlike the solution-phase deposition, alkanethiol islands produced by vapor-phase deposition exhibited markedly higher surface coverages of uniform heights. To illustrate the applicability of this method, metal-ligated multilayers, both with and without an alkanethiol capping layer, were utilized to create nanogaps between Au features using the molecular-ruler process.

A Novel Photoresponsive Azobenzene-Containing Miktoarm Star Polymer: Self-Assembly and Photoresponse Properties

2014 ◽  
Vol 47 (11) ◽  
pp. 3693-3700 ◽  
Author(s):  
Eva Blasco ◽  
Bernhard V. K. J. Schmidt ◽  
Christopher Barner-Kowollik ◽  
Milagros Piñol ◽  
Luis Oriol
Keyword(s):  
Self Assembly ◽  
Star Polymer ◽  
Miktoarm Star

scholarly journals Current Progress in Cross-Linked Peptide Self-Assemblies

2020 ◽  
Vol 21 (20) ◽  
pp. 7577
Author(s):  
Noriyuki Uchida ◽  
Takahiro Muraoka
Keyword(s):  
Self Assembly ◽  
Three Dimensional ◽  
Chemical Properties ◽  
Water Soluble ◽  
Cross Linking ◽  
Physical And Chemical Properties ◽  
Cell Scaffold ◽  
Scaffold Materials ◽  
Physical And Chemical ◽  
And Chemical Properties

Peptide-based fibrous supramolecular assemblies represent an emerging class of biomaterials that can realize various bioactivities and structures. Recently, a variety of peptide fibers with attractive functions have been designed together with the discovery of many peptide-based self-assembly units. Cross-linking of the peptide fibers is a key strategy to improve the functions of these materials. The cross-linking of peptide fibers forming three-dimensional networks in a dispersion can lead to changes in physical and chemical properties. Hydrogelation is a typical change caused by cross-linking, which makes it applicable to biomaterials such as cell scaffold materials. Cross-linking methods, which have been conventionally developed using water-soluble covalent polymers, are also useful in supramolecular peptide fibers. In the case of peptide fibers, unique cross-linking strategies can be designed by taking advantage of the functions of amino acids. This review focuses on the current progress in the design of cross-linked peptide fibers and their applications.

scholarly journals Changes in physical and chemical properties of niosome membrane induced by cholesterol: a promising approach for niosome bilayer intervention

RSC Advances ◽  
2017 ◽  
Vol 7 (78) ◽  
pp. 49463-49472 ◽  
Author(s):  
Mohammad Hadi Nematollahi ◽  
Abbas Pardakhty ◽  
Masoud Torkzadeh-Mahanai ◽  
Mehrnaz Mehrabani ◽  
Gholamreza Asadikaram
Keyword(s):  
Self Assembly ◽  
Nonionic Surfactants ◽  
Chemical Properties ◽  
The Self ◽  
Physical And Chemical Properties ◽  
Physical And Chemical ◽  
And Chemical Properties

Recently, the self-assembly property of nonionic surfactants has been utilized to create vesicles as alternatives to liposomes.

Preparation and Characterization of Nano-Films Materials

2011 ◽  
Vol 492 ◽  
pp. 160-163
Author(s):  
Cai Xia Li ◽  
Qing Lv ◽  
Jie Song ◽  
Dan Yu Jiang ◽  
Qiang Li
Keyword(s):  
Self Assembly ◽  
Chemical Properties ◽  
Layered Compounds ◽  
Insertion Reaction ◽  
Layer By Layer ◽  
Vis Spectroscopy ◽  
Assembly Technique ◽  
Assembly Technology ◽  
Physical And Chemical

Nano-sheets are two-dimensional sheet materials exfoliated from the inorganic layered compounds by various physical and chemical methods. Their unique characteristics insertion reaction and excellent physical and chemical properties have attracted more and more researchers' widespread interests. Selecting quartz glass as the substrate, using layer by layer self-assembly technology, different nano-films materials are prepared. UV/Vis spectroscopy confirmed nano-films materials have been successfully assembled using LBL self-assembly technique. Raman spectrum are mainly used to analyze and characterize the structure of nano-films materials.

scholarly journals Self-assembly of biopolymer films for UV protection of wood

2021 ◽  
Author(s):  
Kristina Ivana Fabijanic ◽  
Aída Ninfa Salinas López ◽  
Long Pan ◽  
Chi-Yuan Cheng ◽  
Yu Wang ◽  
...  
Keyword(s):  
Free Radical ◽  
Self Assembly ◽  
Three Dimensional ◽  
Chemical Properties ◽  
Free Radical Scavenger ◽  
Radical Scavenger ◽  
Ionic Surfactant ◽  
Reducing Ability ◽  
Alternative Material ◽  
Physical And Chemical

AbstractThere is an increasing need for materials with tunable physical and chemical properties that are relatively non-toxic and efficacious for their intended application. Many wood stains and finishes emit toxic chemicals which may have serious implications to one’s health. A novel alternative material is realized between xanthan gum and Neodol, a non-ionic surfactant. The resulting three-dimensional film is evaluated as a free-radical scavenger for the protection of wood at different ratios. Atomic force microscopy visualizes the topography and quantifies the local nanomechanics, while rheological measurements showcase a shift from viscoelastic material to gel. Electron plasmon resonance confirms the free-radical reducing ability (3.5 times), while liquid chromatography mass spectroscopy quantifies the UV degradation of sinapyl alcohol. This material has potential, not only in coating industries as a safer option, but also in those industries requiring flexibility and tenability, namely for biosensors and anti-inflammatory therapeutics. Graphic abstract

Molecular routes to the formation of ordered inorganic arrays

1994 ◽  
Vol 52 ◽  
pp. 478-479
Author(s):  
Brigid R. Hey wood ◽  
Caroline German
Keyword(s):  
Self Assembly ◽  
Chemical Properties ◽  
Inorganic Materials ◽  
Inorganic Particles ◽  
Inorganic Solids ◽  
Ordered Assembly ◽  
External Forces ◽  
Physical And Chemical ◽  
Reliable Methods ◽  
And Chemical Properties

Anisotropic inorganic materials are desirable as they possess unique physical and chemical properties resulting from the manner in which the particulate components assemble. The facility to control the ordering of colloidal inorganic particles could presage dramatic improvements in the fabrication of ceramics, catalysts or paints. Biological systems have already harnessed the manifold advantages of such materials, consider shells, teeth, bones etc.(Figures 1 & 2). Synthetic strategies for the formation of nanodimensional inorganic solids abound but there are few reliable methods currently available for directing their subsequent aggregation. Some degree of ordering can be achieved by the application of external forces (magnetic, electrical) but the aggregates readily dissemble once the stimulus is removed. The requirement is, therefore, for an effective molecular route to the ordered assembly and construction of hierarchical inorganic microstructures.The present work forms part of an extended programme of research investigating crystal tectonics, the ordering of nanodimensional inorganic solids. Here, the controlled morphological tailoring of inorganic crystals to yield a form which favours self-assembly has been investigated.

scholarly journals Rational design and convenient synthesis of a novel family of ruthenium complexes with O,N-bidentate ligands

2005 ◽  
Vol 3 (3) ◽  
pp. 404-416 ◽  
Author(s):  
Renate Drozdzak ◽  
Nele Ledoux ◽  
Bart Allaert ◽  
Ileana Dragutan ◽  
Valerian Dragutan ◽  
...  
Keyword(s):  
Schiff Bases ◽  
Rational Design ◽  
Chemical Properties ◽  
13C Nmr Spectroscopy ◽  
Synthetic Approach ◽  
Bidentate Ligands ◽  
Step Procedure ◽  
Convenient Synthesis ◽  
Ru Complexes ◽  
Physical And Chemical

AbstractA two step procedure for the synthesis of a novel family of homogeneous and immobilized Ru-complexes containing Schiff bases as O,N-bidentate ligands is described. The new Ru-complexes have been structurally characterized by IR, Raman,1H-,13C-NMR spectroscopy. The Schiff bases were associated with a diversity of inorganic and organic ligands such as chloride, phosphane, arenes, various carbenes (alkylidene, vinylidene, indenylidene and allenylidene as well as N-heterocyclic carbenes) and cyclodienes. By choosing a selective range of substituents for the Schiff base, useful physical and chemical properties of the prepared Rucomplexes can be induced. This synthetic approach is promising in creating a valuable and diverse selection of Ru-complexes, valuable for future applications.

Designing low-dimensional nanostructures at surfaces by supramolecular chemistry

2017 ◽  
Author(s):  
Nian Lin ◽  
Sebastian Stepanow
Keyword(s):  
Hydrogen Bonds ◽  
Supramolecular Chemistry ◽  
Self Assembly ◽  
Chemical Properties ◽  
Design Strategies ◽  
Vast Number ◽  
Open Networks ◽  
Nanostructured Systems ◽  
Low Dimensional ◽  
Physical And Chemical

This article describes the use of supramolecular chemistry to design low-dimensional nanostructures at surfaces. In particular, it discusses the design strategies of two types of low-dimensional supramolecular nanostructures: structures stabilized by hydrogen bonds and structures stabilized by metal-ligand co-ordination interactions. After providing an overview of hydrogen-bond systems such as 0D discrete clusters, 1D chains, and 2D open networks and close-packed arrays, the article considers metal-co-ordination systems. It also presents experimental results showing that both hydrogen bonds and metal co-ordination offer protocols to achieve unique nanostructured systems on 2D surfaces or interfaces. Noting that the conventional 3D supramolecular self-assembly has generated a vast number of nanostructures revealing high complexity and functionality, the article suggests that 2D approaches can be applied to substrates with different symmetries as well as physical and chemical properties.

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