scholarly journals Ethnobotany, Phytochemistry and Pharmacological Activity of Kigelia africana (Lam.) Benth. (Bignoniaceae)

Plants ◽  
2020 ◽  
Vol 9 (6) ◽  
pp. 753 ◽  
Author(s):  
Alice Nabatanzi ◽  
Sanah M. Nkadimeng ◽  
Namrita Lall ◽  
John D. Kabasa ◽  
Lyndy J. McGaw

Kigelia africana has been used in the management of human ailments since time immemorial. Ethnobotanists have documented the traditional uses of K. africana, which include treatment of skin disorders, cancer and gynecological complaints, among others. This has interested scientists, who have examined K. africana plant parts for their bioactivity. This review provides an insightful understanding on the ethnobotany, phytochemistry and pharmacology of K. africana. Web search engines Google and Google Scholar, as well as the databases of PubMed, Scopus, JSTOR, HINARI, SID, AJOL and Springer Link, were exhaustively searched using key words and phrases. Institutional reports and conference papers were also consulted. A total of 125 relevant international literature sources meeting the inclusion criteria were included. Kigelia africana has biologically active phytochemicals, many of which have been isolated. Whilst the fruits are most often cited in pharmacological studies, other plant parts are also used in herbal preparations. Commercially available products have been formulated from K. africana, though many have not been fully standardized. Despite many efforts by researchers to scientifically validate traditional uses of K. africana, many remain merely claims, thus the need to conduct more research, scientifically validate other traditional uses, isolate new bioactive phytochemicals and standardize K. africana products.

2020 ◽  
Vol 9 (4) ◽  
pp. 318-327
Author(s):  
Sangeeta Dahiya ◽  
Daizy R. Batish ◽  
Harminader Pal Singh

Pogostemon benghalensis (Burm.f.) Kuntze (Lamiaceae) is an important aromatic plant. Multiple classes of phytochemicals such as flavonoids, phenols, phytosteroids, carbohydrates, fatty acids, glycosides, sterols, terpenoids, tannins, essential oil, and alkaloids have been isolated from the title species. Different plant parts have been used as traditional remedies for various ailments. The present review aims to update and coherent the fragmented information on botanical aspects, phytochemistry, traditional uses, and pharmacological activities. An extensive review of the literature was carried out by using various search engines like PubMed, Scopus, Science Direct, Google Scholar, Google, Scifinder for information. The articles were searched using the keywords "Pogostemon", "Parviflorus’, "benghalensis". Chemical structures of the chemical compounds were drawn using software Chem Draw ultra 8.0. Most of the plant parts have been used for the treatment of various ailments. Phytochemistry reveals that the plant is a rich source of various biologically active compounds. Pogostemon extracts exhibited numerous pharmacological effects like anticancer, anti-inflammatory, antimicrobial and antioxidant activities. In sum, P. benghalensis is a promising aromatic and medicinal plant as depicted by its various traditional uses and pharmacological studies. Bioactive compounds, responsible for its various pharmacological activities at the molecular level, need further detailed investigations. Future clinical studies are also required to validate the various traditional uses of P. benghalensis.


Author(s):  
Alfred Maroyi

Heteromorpha arborescens is an important medicinal plant species throughout its distributional range in tropical Africa. This study evaluated the botany, medicinal uses, and pharmacological activities of H. arborescens. Literature focusing on the botany, phytochemical, pharmacological, and toxicological properties of H. arborescens were obtained from scientific databases such as SCOPUS, Science Direct, PubMed, SciFinder, Medline, and Google Scholar. Pre-electronic literature sources such as book chapters, books, journal articles, conference papers, and other scientific documents were obtained from the University library. Literature search revealed that H. arborescens is used as an aphrodisiac, as herbal medicine for shortness of breath, intestinal worms, inflammation, pain, respiratory problems, skin infections, headache, fever, and malaria. Pharmacological studies of compounds and H. arborescens extracts revealed anthelmintic, antiarthritic, antibacterial, antifungal, anti-inflammatory, antimycobacterial, antinociceptive, antioxidant, antipeptic ulcer, anti-scabies, antispasmodic, antiviral, cytotoxicity, genotoxicity, and uterotonic activities. More detailed research is needed aimed at assessing phytochemical, pharmacological, and toxicological properties of different plant parts and phytochemical compounds isolated from the species.


2021 ◽  
Vol 10 (3) ◽  
pp. 2506-2514

Psidium guajava is a tropical evergreen tree. It belongs to the family Myrtaceae that consists of about 133 genera and approximately 3800 species worldwide. This plant is mainly found in South Africa, North Africa, South America, and Southeast Asia. Psidium guajava is mainly a nutritional plant, but it also shows various biological activities. An array of bioactive constituents, viz; glycosides, terpenoids, tannins, alkaloids, steroids, saponins, amino acids, anthraquinones, proteins, flavonoids, and phenols, etc. have been isolated from Psidium guajava. These phytochemicals are well known for their biological activities, including antibacterial, antioxidant, antifungal, etc. The present work has been performed to gather data about the traditional uses, important phytochemicals, and antibacterial efficiency of Psidium guajava. Many pharmacological studies have demonstrated its antibacterial potential against various important drug resistive pathogens. We invite researchers' attention to carry out detailed antibacterial studies on this valuable plant species to provide reliable knowledge to the patients and discover more novel compounds for the development of new drugs with fewer side effects compared to conventional medicines.


Nutrients ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 2238 ◽  
Author(s):  
Johann Stuby ◽  
Isaac Gravestock ◽  
Evelyn Wolfram ◽  
Giuseppe Pichierri ◽  
Johann Steurer ◽  
...  

The prevalence of obesity is increasing worldwide. Bioactive phytochemicals in food supplements are a trending approach to facilitate dieting and to improve patients’ adherence to reducing food and caloric intake. The aim of this systematic review was to assess efficacy and safety of the most commonly used bioactive phytochemicals with appetite/hunger-suppressing and/or satiety/fullness-increasing properties. To be eligible, studies needed to have included at least 10 patients per group aged 18 years or older with no serious health problems except for overweight or obesity. Of those studies, 32 met the inclusion criteria, in which 27 different plants were tested alone or as a combination, regarding their efficacy in suppressing appetite/hunger and/or increasing satiety/fullness. The plant extracts most tested were derived from Camellia sinensis (green tea), Capsicum annuum, and Coffea species. None of the plant extracts tested in several trials showed a consistent positive treatment effect. Furthermore, only a few adverse events were reported, but none serious. The findings revealed mostly inconclusive evidence that the tested bioactive phytochemicals are effective in suppressing appetite/hunger and/or increasing satiety/fullness. More systematic and high quality clinical studies are necessary to determine the benefits and safety of phytochemical complementary remedies for dampening the feeling of hunger during dieting.


2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
A. K. M. Moyeenul Huq ◽  
Jamia Azdina Jamal ◽  
Johnson Stanslas

Persicaria hydropiper(L.) Delarbre, belonging to Polygonaceae family, is a common weed found in most of the temperate countries including Bangladesh, China, Malaysia, and Japan. The plant is also referred to as “marsh pepper” or “smart weed.” It appears to be a useful herb with evidence-based medicinal properties. The present work addresses the botanical description, traditional uses, phytochemistry, pharmacology, and toxicology ofP. hydropiper. All plant parts have been commonly used in the traditional systems of medicines. Flavonoids are the major group of phytochemical components followed by drimane-type sesquiterpenes and sesquiterpenoids, as well as phenylpropanoids. Different extracts and plant parts showed remarkable pharmacological activities including antioxidant, antibacterial, antifungal, antihelminth, antifeedant, cytotoxicity, anti-inflammatory, antinociceptive, oestrogenicity, antifertility, antiadipogenicity, and neuroprotection. Mutagenicity and acute and subchronic toxicities of the plant were also reported.P. hydropiperhas tremendous medicinal properties that could further be investigated for the development of evidence-based herbal products.


Afrika Focus ◽  
2010 ◽  
Vol 23 (1) ◽  
Author(s):  
Emmy De Caluwé ◽  
Kateřina Halamová ◽  
Patrick Van Damme

Tamarind (Tamarindus indica, Fabaceae), a tropical fruit found in Africa and Asia is highly valued for its pulp. Tamarind fruit pulp has a sweet acidic taste due to a combination of high contents of tartaric acid and reducing sugars. The pulp is used for seasoning, in prepared foods, to flavour confections, curries and sauces, and as a major ingredient in juices and other beverages. Commercial tamarind-based drinks are available from many countries. Vitamin B content is quite high; carotene and vitamin C contents are low. Presence of tannins and other dyeing matters in the seed testa make the whole seed unsuitable for consumption, but they become edible after soaking and boiling in water. Tamarind kernel powder is an important sizing material in textile, paper and jute industries. Seeds are gaining importance as an alternative source of proteins, and are besides rich in some essential minerals. Seed pectin can form gels over a wide pH range. Leaves and flowers can be eaten as vegetables, and are prepared in a variety of dishes. They are used to make curries, salads, stews and soups. Tamarind leaves are a fair source of vitamin C and α-carotene; mineral content is high, particularly P, K, Ca and Mg. Anti-oxidant, anti-inflammatory, anti-microbial and anti-fungal activity has been documented from several plant parts. Tamarind is also extensively used in tradi- tional medicine. The traditional uses, its phytochemistry and pharmacognosy is reviewed to provided with a particular orientation to its value in sub-Sahara Africa. Key words: Tamarind, Tamarindus indica L., traditional use, phytochemistry, pharmacology, amino acids, fatty acids, minerals, vitamins, anti-nutritional factors 


2021 ◽  
Vol 18 ◽  
Author(s):  
S. M. Zahid Hosen ◽  
Md. Junaid ◽  
Muhammad Shaiful Alam ◽  
Maruf Rubayed ◽  
Raju Dash ◽  
...  

Aims: One of the most important resources for the development of new drugs is a biologically active lead compound from natural sources. Biomedical researchers and pharmaceutical companies have a high interest in plant-derived molecules that can be used for drug development. Background: The collective knowledge of plants and their phytoconstituents would be of great benefit for the researchers involved in drug design. Therefore, we developed a unique and dynamic database GreenMolBD, to provide collective information of medicinal plants such as their individual profile, chemical constituents and pharmacological evidence, along with their plant parts and extract types based on different studies. Objective: We have also provided a complete profile of each compound, their physical, quantum, drug-likeliness, and toxicity properties (48 type’s descriptor) using in silico tools. Method: 1846 associated targets, related to individual compounds that are already explored in different studies, are also incorporated and synchronized. Result: GreenMolBD is freely accessible and searchable by keywords, plant name, synonym, common name, family name, family synonym, compound name, synonym, IUPAC name, InChI Key, target name and disease name. Conclusion: This is the first evidence-based database of bioactive molecules from medicinal plants specially grown in Bangladesh, which may help to explore and foster nature-inspired rational drug discovery in the future. Our database is continuously updating with the new information.


2016 ◽  
Vol 2016 ◽  
pp. 1-36 ◽  
Author(s):  
Xin Mao ◽  
Ling-Fang Wu ◽  
Hong-Ling Guo ◽  
Wen-Jing Chen ◽  
Ya-Ping Cui ◽  
...  

The plants of the genusPhyllanthus(Euphorbiaceae) have been used as traditional medicinal materials for a long time in China, India, Brazil, and the Southeast Asian countries. They can be used for the treatment of digestive disease, jaundice, and renal calculus. This review discusses the ethnopharmacological, phytochemical, and pharmacological studies ofPhyllanthusover the past few decades. More than 510 compounds have been isolated, the majority of which are lignins, triterpenoids, flavonoids, and tannins. The researches of their remarkable antiviral, antioxidant, antidiabetic, and anticancer activities have become hot topics. More pharmacological screenings and phytochemical investigations are required to support the traditional uses and develop leading compounds.


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