scholarly journals Toxic Effects of Single Antibiotics and Antibiotics in Combination on Germination and Growth of Sinapis alba L.

Plants ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 107 ◽  
Author(s):  
Ulrike Timmerer ◽  
Lennart Lehmann ◽  
Ewald Schnug ◽  
Elke Bloem
Keyword(s):  
Synergistic Effects ◽  
Farmyard Manure ◽  
Antibiotic Resistance Genes ◽  
Sinapis Alba ◽  
Sinapis Alba L ◽  
Open Questions ◽  
Lower Effect ◽  
Pot Trial ◽  
High Concentrations ◽  
The Impact

Antibiotics enter agro-ecosystems via the application of farmyard manure, sewage sludge, animal by-products, or digestates. There are many open questions regarding the behavior of such compounds in the soil like their adsorption, degradation, half-life, and their effects on soil organisms and plants. The impact of antibiotics on the development of antibiotic resistance genes in the environment is regarded as the most important effect that endangers the environment as well as human health. Nevertheless, direct plant toxicity, especially of different antibiotics and heavy metals at the same time, can be of importance as well. In the current study, commercially available phytotoxkits were tested with regard to the toxicity of single antibiotics and antibiotics in combination with the root growth of Sinapis alba L. Additionally, a pot trial was conducted to study the transfer of the observed phytotoxkits results in more complex systems. The phytotoxkits revealed direct toxicity of antibiotics on root development only at high concentrations. The highest toxicity was determined for sulfadiazine, followed by tetracycline and enrofloxacin, showing the least toxicity. When two antibiotics were tested at the same time in the phytotoxkit, synergistic effects were detected. The pot trial indicated lower effect concentrations for enrofloxacin than determined in the phytotoxkit and, therefore, to higher toxicity on plant growth.

DAMPAK PROGRAM DIKLAT ONLINE TIK GURU PUSTEKKOM TERHADAP AKSESBILITAS KONTEN PEMBELAJARAN PADA FITUR RUMAH BELAJAR

2018 ◽  
Vol 19 (2) ◽  
pp. 84
Author(s):  
Eni Susilawati
Keyword(s):  
Teacher Training ◽  
Quantitative Research ◽  
Online Training ◽  
Research Approach ◽  
Intensity Level ◽  
Web Based ◽  
Learning Content ◽  
Open Questions ◽  
Ict Training ◽  
The Impact

The research objective is to analyze the impact of the participation of online  ICT teacher training to increase the number of accessibility the learning content of features in Rumah Belajar. This research used the quantitative research approach with descriptive quantitative analysis methods to be able to describe how the increase in accessibility features of Rumah Belajar and utilization in learning in school. Samples were selected in this study are all online training participants at 15 locations online training that has been conducted by Pustekkom in 2015 and 2016 in 2015. The data was collected using a questionnaire and a list of open questions in accordance with the purpose of research. The results showed that 1) online ICT teacher training participants, after completing the Pustekkom  training online  using become more motivated to access other feature in Rumah Belajar; 2) The order of the percentage of the intensity level of accessibility to the other features of Rumah Belajar are: Sumber Belajar 23%, BSE 23%, Bank Soal 21%, Kelas Maya 13%, Lab Maya 6%, Karya Guru 4%, Wahana Jelajah Angkasa 4%, Peta Budaya 4% and Karya Komunitas 2%, and ICT training online using the application PKB Rumah Belajar can be used as a reference for efforts to develop a web-based learning applications, in particular for the development of Rumah belajar portal belongs Pustekkom Kemendikbud. Tujuan penelitian yaitu untuk menganalisis dampak keikutsertaan diklat online  TIK guru Belajar terhadap peningkatan jumlah aksebilitas konten pembelajaran pada fitur-fitur rumah belajar. Penelitian ini menggunakan pendekatan penelitian kuantitatif dengan metode analisis kuantitatif secara deskriptif untuk bisa menggambarkan bagaimana peningkatan aksesbilitas fitur-fitur rumah belajar dan pemanfaatannya dalam pembelajaran di sekolah. Sampel yang dipilih dalam penelitian ini adalah semua peserta diklat online  pada 15 lokasi diklat online yang telah dilaksanakan oleh Pustekkom pada tahun 2015 dan 2016. Pengumpulan data menggunakan kuesioner dan daftar pertanyaan terbuka sesuai dengan tujuan penelitian. Hasil penelitian menunjukkan bahwa 1) peserta diklat online TIK Guru, setelah mengikuti diklat online Pustekkom, menjadi lebih termotivasi untuk mengakses fitur-fitur lainnya dalam Rumah Belajar; 2) Urutan prosentase tingkat intensitas aksesbilitas terhadap fitur-fitur Rumbel selain Pengembangan Keprofesian berkelanjutan (PKB) adalah: Sumber Belajar 23%, Buku Sekolah Elektronik (BSE) 23%, Bank Soal 21%, Kelas Maya 13%, Lab Maya 6%, Karya Guru 4%, Wahana Jelajah Angkasa 4%, Peta Budaya 4% dan Karya Komunitas 2%; dan 3) diklat online TIK menggunakan aplikasi PKB. Rumah belajar bisa dijadikan referensi bagi upaya pengembangan aplikasi pembelajaran berbasis web, khususnya bagi pengembangan portal Rumah Belajar milik Pustekkom Kemendikbud.

scholarly journals Spatial Variation of Water Chemistry in Aries River Catchment Western Romania

2021 ◽  
Vol 11 (14) ◽  
pp. 6592
Author(s):  
Ana Moldovan ◽  
Maria-Alexandra Hoaghia ◽  
Anamaria Iulia Török ◽  
Marius Roman ◽  
Ionut Cornel Mirea ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Water Quality ◽  
Water Chemistry ◽  
Water Samples ◽  
Mine Drainage ◽  
Pollution Indices ◽  
Mining Activities ◽  
River Catchment ◽  
High Concentrations ◽  
The Impact

This study aims to investigate the quality and vulnerability of surface water (Aries River catchment) in order to identify the impact of past mining activities. For this purpose, the pollution and water quality indices, Piper and Durov plots, as well vulnerability modeling maps were used. The obtained results indicate that the water samples were contaminated with As, Fe, Mn, Pb and have relatively high concentrations of SO42−, HCO3−, TDS, Ca, K, Mg and high values for the electrical conductivity. Possible sources of the high content of chemicals could be the natural processes or the inputs of the mine drainage. Generally, according to the pollution indices, which were correlated to high concentrations of heavy metals, especially with Pb, Fe and Mn, the water samples were characterized by heavy metals pollution. The water quality index classified the studied water samples into five different classes of quality, namely: unsuitable for drinking, poor, medium, good and excellent quality. Similarly, medium, high and very high vulnerability classes were observed. The Durov and Piper plots classified the waters into Mg-HCO3− and Ca-Cl− types. The past and present mining activities clearly change the water chemistry and alter the quality of the Aries River, with the water requiring specific treatments before use.

scholarly journals Effect of Maritime Traffic on Water Quality Parameters in Santa Marta, Colombia

2021 ◽  
Vol 9 (5) ◽  
pp. 474
Author(s):  
René Rodríguez-Grimón ◽  
Nestor Hernando Campos ◽  
Ítalo Braga Castro
Keyword(s):  
Water Quality ◽  
Petroleum Hydrocarbons ◽  
Quality Parameters ◽  
Water Quality Parameters ◽  
Maritime Traffic ◽  
Natural Park ◽  
High Concentrations ◽  
The Impact ◽  
The Relationship ◽  
Multiple Chemical

Since 2013, there has been an increase (>23%) in naval traffic using maritime routes and ports on the coastal fringe of Santa Marta, Colombia. Of major concern, and described by several studies, is the relationship between maritime traffic and coastal contamination. This study proposed a maritime traffic indicator considering the simultaneous effects of several relevant measurements of water quality parameters to estimate the impact of naval activity. The approach involved developing a model including the number of vessels, hull length, and permanence time in berths. In addition, water quality variables, considering climatic seasons, were used to verify association with maritime traffic and touristic activities. The high concentrations of total coliforms (TC) and dissolved/dispersed petroleum hydrocarbons in chrysene equivalents (DDPH) reported by the International Marina of Santa Marta (SM) were affected by the local anthropic activities, including tourism, naval traffic, and urban wastewater discharges. Moreover, our results suggest the occurrence of multiple chemical impacts within Tayrona National Natural Park (PNNT) affecting conservation goals. The estimation of the maritime traffic indicator proposed in this study may be an easy and more complete tool for future studies evaluating the impact of naval activities on environmental quality.

VP37 Patient Involvement In EUnetHTA Assessments (Non-Pharma Technologies)

2019 ◽  
Vol 35 (S1) ◽  
pp. 85-85
Author(s):  
Sabine Ettinger ◽  
Judit Erdos ◽  
Cecilia De Villiers
Keyword(s):  
Quality Of Life ◽  
Patient Involvement ◽  
Health Related Quality ◽  
Patient Organizations ◽  
Open Questions ◽  
Related Quality ◽  
Patient Representatives ◽  
Health Related ◽  
The Impact

IntroductionPatients can provide valuable experience on living with diseases, health-related quality of life, various therapies and relevant outcomes. Their input and perspectives can be helpful in complementing health technology assessment (HTA) processes. The European Network for HTA (EUnetHTA), funded by the European Commission, aims to further advance and standardise patient involvement processes in order to add to the quality and applicability of HTAs and to allow capability building.MethodsDifferent methods for patient involvement in HTAs on non-pharmaceutical technologies were tested: Patient input templates (open questions sent to relevant patient organizations, or published on EUnetHTA website); scoping meeting with patients/patient representatives; one-on-one conversation and group conversation. Applied methods depended on the scope of the HTA and other factors like timelines of HTAs and burden of disease for patients.ResultsPatients were included in eight of sixteen HTAs on non-pharmaceutical technologies. Applied methods were: group conversation (n = 2), scoping meeting (n = 1), patient input templates (n = 4), one-on-one conversation (n = 2,) and other approach (i.e. written feedback on scope n= 2). In some HTAs more than one method was used. Main reasons for not including patients were inability to identify suitable patients or tight timelines. Patients' feedback on health-related quality of life and outcome measures proved most useful in the scoping phase.ConclusionsThe different approaches were useful for complementing HTA processes. Those need to be further tested and evaluated in order to formulate deeper understanding about the impact of patient involvement on HTA. Additionally, feedback from patients that were actively involved in the HTAs should be collected to further improve the involvement methods that should serve as basis for future recommendations post 2020.

scholarly journals A New Approach for Design Optimization and Parametric Analysis of Symmetric Compound Parabolic Concentrator for Photovoltaic Applications

2021 ◽  
Vol 13 (9) ◽  
pp. 4606
Author(s):  
Faisal Masood ◽  
Perumal Nallagownden ◽  
Irraivan Elamvazuthi ◽  
Javed Akhter ◽  
Mohammad Azad Alam
Keyword(s):  
Parametric Analysis ◽  
Concentration Ratio ◽  
Synergistic Effects ◽  
Geometric Optimization ◽  
Design Parameters ◽  
Imaging Device ◽  
Compound Parabolic Concentrator ◽  
Photovoltaic Applications ◽  
Half Angle ◽  
The Impact

A compound parabolic concentrator (CPC) is a non-imaging device generally used in PV, thermal, or PV/thermal hybrid systems for the concentration of solar radiation on the target surface. This paper presents the geometric design, statistical modeling, parametric analysis, and geometric optimization of a two-dimensional low concentration symmetric compound parabolic concentrator for potential use in building-integrated and rooftop photovoltaic applications. The CPC was initially designed for a concentration ratio of “2×” and an acceptance half-angle of 30°. A MATLAB code was developed in house to provoke the CPC reflector’s profile. The height, aperture width, and concentration ratios were computed for different acceptance half-angles and receiver widths. The interdependence of optical concentration ratio and acceptance half-angle was demonstrated for a wide span of acceptance half-angles. The impact of the truncation ratio on the geometric parameters was investigated to identify the optimum truncation position. The profile of truncated CPC for different truncation positions was compared with full CPC. A detailed statistical analysis was performed to analyze the synergistic effects of independent design parameters on the responses using the response surface modeling approach. A set of optimized design parameters was obtained by establishing specified optimization criteria. A 50% truncated CPC with an acceptance half-angle of 21.58° and receiver width of 193.98 mm resulted in optimum geometric dimensions.

Are neutrophil extracellular traps the link for the cross-talk between periodontitis and rheumatoid arthritis physiopathology?

Rheumatology ◽  
2021 ◽  
Author(s):  
Sicília Rezende Oliveira ◽  
José Alcides A de Arruda ◽  
Ayda Henriques Schneider ◽  
Valessa Florindo Carvalho ◽  
Caio Machado ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Cross Talk ◽  
Neutrophil Extracellular Traps ◽  
Periodontal Therapy ◽  
Clinical Parameters ◽  
Extracellular Traps ◽  
Early Ra ◽  
The Cross ◽  
High Concentrations ◽  
The Impact

Abstract Objectives Neutrophil extracellular traps (NETs) play a role in the pathogenesis of periodontitis and rheumatoid arthritis (RA). However, it remains poorly understood whether NETs participate in the cross-talk between periodontitis and RA. Herein, we investigated the production of NETs in individuals with periodontitis and RA and its association with clinical parameters. The impact of periodontal therapy on RA and NET release was also assessed. Methods The concentration of NETs and cytokines was determined in the saliva and plasma of individuals with early RA (n = 24), established RA (n = 64), and individuals without RA (n = 76). The influence of periodontitis on the production of NETs and cytokines was also evaluated. Results Individuals with early RA had a higher concentration of NETs in saliva and plasma than individuals with established RA or without RA. Periodontitis resulted in an increase in the concentration of NETs of groups of individuals without RA and with early RA. The proportion of individuals with high concentrations of IL-6, IL-10 and GM-CSF was higher among individuals with periodontitis than among individuals without periodontitis. The concentrations of TNF-α, IL-6, IL-17/IL-25, and IL-28A were particularly high in individuals with early RA. Worse periodontal clinical parameters, RA onset and RA activity were significantly associated with circulating NETs. Periodontal therapy was associated with a reduction in the concentration of NETs and inflammatory cytokines and amelioration in periodontitis and RA. Conclusion This study reveals that NETs are a possible link between periodontitis and RA, with periodontal therapy resulting in a dramatic switch in circulating NET levels.

scholarly journals Phytotoxicity of Tires Evaluated in Simulated Conditions

Environments ◽  
2021 ◽  
Vol 8 (6) ◽  
pp. 49
Author(s):  
Markéta Šourková ◽  
Dana Adamcová ◽  
Jan Winkler ◽  
Magdalena Daria Vaverková
Keyword(s):  
Higher Plants ◽  
Sinapis Alba ◽  
Lepidium Sativum ◽  
Root Growth Inhibition ◽  
Chemical Parameters ◽  
Sinapis Alba L ◽  
Test Kit ◽  
Physical And Chemical ◽  
Aqueous Leachate ◽  
Lepidium Sativum L

Illegal dumps and landfills with disposed of tires are a fact of today, which should not be neglected as they represent a great ecological burden for the environment, affect the surrounding nature and disturb the landscape. This research was focused on testing the phytotoxicity of aqueous leachates from the fractions of tires in two sets of experiments—to simulate laboratory conditions (tire leaching in distilled water) and natural conditions (tire leaching in water from a recipient) using the Phytotoxkit testing kit (kit for the establishment of inhibition/stimulation effect on the root development) and the watercress test of phytotoxicity (biological method for the assessment of leachate phytotoxicity). Plants whose seeds were selected for the test were watercress (Lepidium sativum L.) and white mustard (Sinapis alba L.). The aqueous leachate was tested for 38 weeks. During the experiment, physical and chemical parameters were measured at intervals of 14 days by the testing instrument HACH TEST KIT: electric conductivity (EC), amount of dissolved oxygen (LDO) and pH. Results of root growth inhibition (IR) on the seeds of Lepidium sativum L. and Sinapis alba L. exhibited values ranging from 11.73% to 47.74% in the tested samples. Results of germination index (GI) on the seeds of Lepidium sativum L. exhibited values below 66% in the tested samples, which indicated the leachate phytotoxicity. In spite of the fact that similar studies are tackling the acute toxicity of leachates from tires (particularly to algae, embryos and animals), this research brings complementary information in testing the acute phytotoxicity of tire leachates to higher plants.

scholarly journals XarxaSalut, network of municipalities for health, Valencia Region (Spain): policy process evaluation

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
R Peiró Pérez ◽  
E Pérez Sanz ◽  
E Legaz Sanchez ◽  
J Quiles Izquierdo ◽  
Grupo XarxaSalut
Keyword(s):  
Process Evaluation ◽  
Citizen Participation ◽  
Policy Process ◽  
Local Level ◽  
Common Language ◽  
Health Authorities ◽  
Open Questions ◽  
Economic Support ◽  
Public Health Authorities ◽  
The Impact

Abstract “XarxaSalut” started in 2017, with the municipalities that have taken the commitment to boost the Promotion of Health (HP) at the local level through community participation, intersectorality and equity perspective. The objective is to present a policy process evaluation (2'5 years) of the implementation of XarxaSalut. Different approaches have been used; a questionnaire addressed to the municipalities at the time of adhesion including data on intersectorality, participation, HP actions and open questions; description of instruments that Regional Public Health Authorities (RPHA) has mobilized and an analysis of barriers and strengths made by the coordination office. In 2017, 17 municipalities were joined, being 197 in February 2020 (70% of the population). 65% are in a process of an organizational change through the intersectoral, decision making and participative working group. 35% are doing analysis of determinants and /or health situation, assets maps and a prioritization of HP actions. The main barriers identified by municipalities are lack of economic and personal resources, and difficulties in achieve citizen participation. The main benefits were the optimization of resources, the exchange of experiences, training, or economic support from the RPHA. Some support instruments develop for RPHA are a collection of guides for community development, funds that the municipalities can apply to support actions related with training, HP action on vulnerable population, on asset maps, participation processes, vulnerable neighborhoods, etc.; Community actions have been included in the “Health Observatory” to give visibility and social support to XarxaSalut. Interdisciplinary training processes with health and municipal professionals have been made in order to develop a common language and strength the competences for HP. Lesson learned: The need to improve coordination and a common language between different types of participants and professionals Key messages The decision makers and professionals in the municipalities understand the impact in health of the policies developed at local level but needs guide and support to deal with it. The coordination between different administrations and primary health at local level and the misunderstandings about health and their determinants are the main aspect to reinforce.

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