scholarly journals Zebrafish as a Model for Fish Diseases in Aquaculture

Pathogens ◽  
2020 ◽  
Vol 9 (8) ◽  
pp. 609
Author(s):  
Louise von Gersdorff Jørgensen
Keyword(s):  
Animal Models ◽  
Fish Species ◽  
In Vivo Imaging ◽  
Transgenic Zebrafish ◽  
Parasitic Diseases ◽  
Fish Diseases ◽  
Immunological Responses ◽  
Infection Biology

The use of zebrafish as a model for human conditions is widely recognized. Within the last couple of decades, the zebrafish has furthermore increasingly been utilized as a model for diseases in aquacultured fish species. The unique tools available in zebrafish present advantages compared to other animal models and unprecedented in vivo imaging and the use of transgenic zebrafish lines have contributed with novel knowledge to this field. In this review, investigations conducted in zebrafish on economically important diseases in aquacultured fish species are included. Studies are summarized on bacterial, viral and parasitic diseases and described in relation to prophylactic approaches, immunology and infection biology. Considerable attention has been assigned to innate and adaptive immunological responses. Finally, advantages and drawbacks of using the zebrafish as a model for aquacultured fish species are discussed.

Systematic review: In vivo imaging in animal models relevant to drug-induced Interstitial lung disease (DIILD)

2018 ◽  
Author(s):  
Irma Mahmutovic Persson ◽  
Karin Von Wachenfeldt ◽  
Kashmira Pindoria ◽  
Juan A. Delgado-San Martin ◽  
Simon Campbell ◽  
...  
Keyword(s):  
Systematic Review ◽  
Interstitial Lung Disease ◽  
Animal Models ◽  
Lung Disease ◽  
In Vivo Imaging ◽  
Drug Induced

In Vivo Imaging Applications for the Nervous System in Animal Models

2011 ◽  
pp. 253-269 ◽  
Author(s):  
Kathy Gabrielson ◽  
Craig Fletcher ◽  
Paul W. Czoty ◽  
Michael A. Nader ◽  
Tracy Gluckman
Keyword(s):  
Nervous System ◽  
Animal Models ◽  
In Vivo Imaging

In vivo imaging of neural activities along the olfactory circuitry in transgenic zebrafish

2011 ◽  
Vol 71 ◽  
pp. e357
Author(s):  
Tetsuya Koide ◽  
Masamichi Ohkura ◽  
Junichi Nakai ◽  
Yoshihiro Yoshihara
Keyword(s):  
In Vivo Imaging ◽  
Transgenic Zebrafish ◽  
Neural Activities

scholarly journals Multiphoton in vivo imaging of amyloid in animal models of Alzheimer’s disease

2010 ◽  
Vol 59 (4-5) ◽  
pp. 268-275 ◽  
Author(s):  
Jinghui Dong ◽  
Raquel Revilla-Sanchez ◽  
Stephen Moss ◽  
Philip G. Haydon
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Animal Models ◽  
In Vivo Imaging

Generation and characterisation of novel transgenic zebrafish allowing in vivo imaging of endothelial cell biology

2016 ◽  
Vol 244 ◽  
pp. e10 ◽  
Author(s):  
A.M. Savage ◽  
C. Mayo ◽  
H.R. Kim ◽  
E. Markham ◽  
F.J.M. van Eeden ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
In Vivo Imaging ◽  
Cell Biology ◽  
Transgenic Zebrafish

scholarly journals Correlation of In Vivo Imaging To Morphomolecular Pathology In Translational Research – Challenge Accepted

2021 ◽  
Author(s):  
Simone Ballke ◽  
Irina Heid ◽  
Carolin Mogler ◽  
Rickmer Braren ◽  
Markus Schwaiger ◽  
...  
Keyword(s):  
Animal Models ◽  
In Vivo Imaging ◽  
Collaborative Research ◽  
Ex Vivo ◽  
Point Of View ◽  
Imaging Methods ◽  
Experimental Pathology ◽  
University Of Munich ◽  
Research Challenge

Abstract Correlation of in vivo imaging to histomorphological pathology in animal models requires comparative interdisciplinary expertise of different fields of medicine. From the morphological point of view, there is an urgent need to improve histopathological evaluation in animal model based research to expedite translation into clinical applications. While different other fields of translational science were standardized over the last years, little was done to improve the pipeline of experimental pathology to ensure reproducibility based on pathological expertise in experimental animal models with respect to defined guidelines and classifications. Additionally, longitudinal analyses of preclinical models often use a variety of imaging methods and much more attention should be drawn to enable for proper co-registration of in vivo imaging methods with the ex vivo morphological read-outs. Here we present the development of the Comparative Experimental Pathology (CEP) unit embedded in the Institute of Pathology of the Technical University of Munich during the Collaborative Research Center 824 (CRC824) funding period together with selected approaches of histomorphological techniques for correlation of in vivo imaging to morphomolecular pathology.

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