scholarly journals Editorial Comments to the Special Issue: “Aggregatibacter actinomycetemcomitans—Gram-Negative Bacterial Pathogen”

Pathogens ◽  
2020 ◽  
Vol 9 (6) ◽  
pp. 441
Author(s):  
Jan Oscarsson ◽  
Joseph DiRienzo ◽  
Anders Johansson

Aggregatibacter actinomycetemcomitans is a periodontal pathogen colonizing the oral cavity in many individuals of the human population. It is equipped with several potent virulence factors that can cause cell death and induce or evade the host inflammatory response. Both harmless and highly virulent genotypes of the bacterium have emerged because of the large genetic diversity within the species. The oral condition and age, as well as the geographic origin of the individual, influence the risk to be colonized by a virulent genotype of the bacterium. In the present editorial, the different genetic and virulence properties of A. actinomycetemcomitans will be addressed in relation to the publications in this Special Issue.

Pathogens ◽  
2019 ◽  
Vol 8 (4) ◽  
pp. 222 ◽  
Author(s):  
Belibasakis ◽  
Maula ◽  
Bao ◽  
Lindholm ◽  
Bostanci ◽  
...  

Aggregatibacter actinomycetemcomitans is a periodontal pathogen colonizing the oral cavity of a large proportion of the human population. It is equipped with several potent virulence factors that can cause cell death and induce or evade inflammation. Because of the large genetic diversity within the species, both harmless and highly virulent genotypes of the bacterium have emerged. The oral condition and age, as well as the geographic origin of the individual, influence the risk to be colonized by a virulent genotype of the bacterium. In the present review, the virulence and pathogenicity properties of A. actinomycetemcomitans will be addressed.


Author(s):  
Jakub Čapek ◽  
Sophie Loidolt

AbstractThis special issue addresses the debate on personal identity from a phenomenological viewpoint, especially contemporary phenomenological research on selfhood. In the introduction, we first offer a brief survey of the various classic questions related to personal identity according to Locke’s initial proposal and sketch out key concepts and distinctions of the debate that came after Locke. We then characterize the types of approach represented by post-Hegelian, German and French philosophies of the nineteenth and twentieth centuries. We argue that whereas the Anglophone debates on personal identity were initially formed by the persistence question and the characterization question, the “Continental” tradition included remarkably intense debates on the individual or the self as being unique or “concrete,” deeply temporal and—as claimed by some philosophers, like Sartre and Foucault—unable to have any identity, if not one externally imposed. We describe the Continental line of thinking about the “self” as a reply and an adjustment to the post-Lockean “personal identity” question (as suggested by thinkers such as MacIntyre, Ricœur and Taylor). These observations constitute the backdrop for our presentation of phenomenological approaches to personal identity. These approaches run along three lines: (a) debates on the layers of the self, starting from embodiment and the minimal self and running all the way to the full-fledged concept of person; (b) questions of temporal becoming, change and stability, as illustrated, for instance, by aging or transformative life-experiences; and (c) the constitution of identity in the social, institutional, and normative space. The introduction thus establishes a structure for locating and connecting the different contributions in our special issue, which, as an ensemble, represent a strong and differentiated contribution to the debate on personal identity from a phenomenological perspective.


2021 ◽  
Vol 50 (1) ◽  
pp. 3-11
Author(s):  
Barbara Schulte ◽  
Marina Svensson

This special issue approaches information and communication technologies (ICT) visions and their realisation/implementation at various levels, among different actors and from various perspectives. Conceptually, we distinguish three different dimensions, even though those overlap in the individual contributions as well as in empirical reality – namely ideational, instrumental, and relational. The different contributions address both visions formulated by the Chinese state and by individual actors such as entrepreneurs. Even though the conditions for the use of ICT in China are deeply affected by state governance, this governance is in no way tantamount to one single government. As this issue’s contributions show, state attempts at building a stable cyber-governance are in need of allies and, depending on the allies’ visions and other, competitive visions, the outcomes of these dynamics are seldom truthful realisations of one original grand masterplan.


Zootaxa ◽  
2012 ◽  
Vol 3323 (1) ◽  
pp. 27 ◽  
Author(s):  
PAVEL SROKA ◽  
ALEXANDER V. MARTYNOV ◽  
ROMAN J. GODUNKO

Specimens of Baetis (Rhodobaetis) braaschi Zimmermann, 1980 from the three distant geographic regions (Crimean Pen-insula, Eastern Ukraine and Caucasus) are investigated and compared using a methodological approach combining mor-phological and molecular (partial mtDNA COI sequences) data. Intraspecific variability in several morphologicalcharacters is recognized and described, whereas COI sequences are found to be very uniform. The amount and distributionof the changes of COI sequences do not follow the pattern of morphological variability and/or geographic origin of thespecimens. This indicates that analysis of the changes in the COI sequence can contradict the pattern of morphologicalcharacters commonly used for the discrimination of the individual Rhodobaetis species. As a basis for the future taxonom-ic changes concerning subgenus Rhodobaetis, it is advised (where possible) to critically evaluate both molecular and morphological data.


2021 ◽  
Vol 13 (3) ◽  
pp. 459-481
Author(s):  
Nikolay Hakimov ◽  
Ad Backus

Abstract The influence of usage frequency, and particularly of linguistic similarity on human linguistic behavior and linguistic change in situations of language contact are well documented in contact linguistics literature. However, a theoretical framework capable of unifying the various explanations, which are usually couched in either structuralist, sociolinguistic, or psycholinguistic parlance, is still lacking. In this introductory article we argue that a usage-based approach to language organization and linguistic behavior suits this purpose well and that the study of language contact phenomena will benefit from the adoption of this theoretical perspective. The article sketches an outline of usage-based linguistics, proposes ways to analyze language contact phenomena in this framework, and summarizes the major findings of the individual contributions to the special issue, which not only demonstrate that contact phenomena are usefully studied from the usage-based perspective, but document that taking a usage-based approach reveals new aspects of old phenomena.


Author(s):  
Roland Wirth ◽  
Bernadett Pap ◽  
Gergely Maróti ◽  
Péter Vályi ◽  
Laura Komlósi ◽  
...  

Periodontitis is caused by pathogenic subgingival microbial biofilm development and dysbiotic interactions between host and hosted microbes. A thorough characterization of the subgingival biofilms by deep amplicon sequencing of 121 individual periodontitis pockets of nine patients and whole metagenomic analysis of the saliva microbial community of the same subjects were carried out. Two biofilm sampling methods yielded similar microbial compositions. Taxonomic mapping of all biofilms revealed three distinct microbial clusters. Two clinical diagnostic parameters, probing pocket depth (PPD) and clinical attachment level (CAL), correlated with the cluster mapping. The dysbiotic microbiomes were less diverse than the apparently healthy ones of the same subjects. The most abundant periodontal pathogens were also present in the saliva, although in different representations. The single abundant species Tannerella forsythia was found in the diseased pockets in about 16–17-fold in excess relative to the clinically healthy sulcus, making it suitable as an indicator of periodontitis biofilms. The discrete microbial communities indicate strong selection by the host immune system and allow the design of targeted antibiotic treatment selective against the main periodontal pathogen(s) in the individual patients.


2020 ◽  
Vol Special issue on... ◽  
Author(s):  
Benjamin Molineaux ◽  
Bettelou Los ◽  
Martti Mäkinen

International audience The advent of ever-larger and more diverse historical corpora for different historical periods and linguistic varieties has led to the impossibility of obtaining simple, direct-and yet balancedrepresentations of the core patterns in the data. In order to draw insights from heterogeneous and complex materials of this type, historical linguists have begun to reach for a growing number of data visualisation techniques, from the statistical, to the cartographical, the network-based and beyond. An exploration of the state of this art was the objective of a workshop at the 2018 International Conference on English Historical Linguistics, from whence most of the materials of this Special Issue are drawn. This brief introductory paper outlines the background and relevance of this line of methodological research and presents a summary of the individual papers that make up the collection.


2021 ◽  
Vol 35 (2-3) ◽  
pp. 209-214
Author(s):  
Frank Fischer

Abstract. This discussion first highlights novel aspects that the individual articles contribute to the special issue on (future) teachers' choice, use, and evaluation of (non-)scientific information sources about educational topics. Among these highlights are the conceptualizations of epistemic goals and the type of pedagogical task as moderators of the selection and use of scientific evidence. The second part raises overarching questions, including the following: How inclusive do we want the concept of evidence to be? How should teachers use research evidence in their pedagogical problem-solving and decision-making? To what extent is multidisciplinary teacher education contributing to epistemological confusion, possibly leading to (pre-service) teachers' low appreciation of educational research?


2019 ◽  
Vol 12 (2) ◽  
pp. 99-114
Author(s):  
Maren Freudenberg ◽  
Tim Weitzel

The introduction to the special issue on ‘charisma’ offers a very brief overview of the development of the concept in the social sciences and various critiques and intersecting debates. It casts a close look at Max Weber’s sometimes contradictory use of the concept and the different ways he conceptualized it in his sociology of religion and his sociology of domination. It then examines alternative theoretical approaches to ‘charisma’ that emerge in the course of the twentieth century before outlining this special issue’s contribution to the conceptual debate and the individual articles’ operationalization of the term by viewing charisma as relational, communicative, procedural, as well as related to ideas, practices, and objects.


2019 ◽  
Vol 63 (2) ◽  
pp. 143-150 ◽  
Author(s):  
Aparecida Vilaça

This afterword offers a commentary on the concept of relations discussed in the introduction and the individual contributions to this special issue by critically reflecting on the key concepts that have emerged in it. It contributes to the discussion with a reflection on the use of the term parente in Amazonia, showing how its exclusive use in inter-ethnic contexts indicates a play of perspective in the way that relations between different groups of people are experienced.


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