scholarly journals Eating Dinner Early Improves 24-h Blood Glucose Levels and Boosts Lipid Metabolism after Breakfast the Next Day: A Randomized Cross-Over Trial

Nutrients ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 2424
Author(s):  
Kaho Nakamura ◽  
Eri Tajiri ◽  
Yoichi Hatamoto ◽  
Takafumi Ando ◽  
Seiya Shimoda ◽  
...  

Aim To examine whether mild early time-restricted eating (eating dinner at 18:00 vs. at 21:00) improves 24-h blood glucose levels and postprandial lipid metabolism in healthy adults. Methods Twelve participants (2 males and 10 females) were included in the study. In this 3-day (until the morning of day 3) randomized crossover study, two different conditions were tested: eating a late dinner (at 21:00) or an early dinner (at 18:00). During the experimental period, blood glucose levels were evaluated by each participant wearing a continuous blood glucose measuring device. Metabolic measurements were performed using the indirect calorimetry method on the morning of day 3. The study was conducted over three days; day 1 was excluded from the analysis to adjust for the effects of the previous day’s meal, and only data from the mornings of days 2 and 3 were used for the analysis. Results Significant differences were observed in mean 24-h blood glucose levels on day 2 between the two groups (p = 0.034). There was a significant decrease in the postprandial respiratory quotient 30 min and 60 min after breakfast on day 3 in the early dinner group compared with the late dinner group (p < 0.05). Conclusion Despite a difference of only 3 h, eating dinner early (at 18:00) has a positive effect on blood glucose level fluctuation and substrate oxidation compared with eating dinner late (at 21:00).

1963 ◽  
Vol 18 (6) ◽  
pp. 1221-1225 ◽  
Author(s):  
John T. Attebery ◽  
Harry W. Colvin

Fourteen male Holstein-Fresian calves, 3–4 days of age, were placed on one of four diets for a 13-week experimental period. The diets included the following: milk and milk solids; milk and grain; milk, grain, and hay, inoculated (rumen ingesta from a mature steer introduced via stomach tube into the rumen of an experimental calf); or milk and grain, inoculated. Significant differences were noted in the effect of diet, age, and the interaction of diet and age on the fasting level of blood glucose. The calves on the diet containing milk and milk solids maintained a constant level of fasting blood glucose; however, the inclusion of grain and hay in the diet resulted in a decline of the fasting blood glucose. The rumen inoculation of one of the groups of calves on the milk and grain diet did not result in a fasting blood glucose which was statistically different from that of the calves not inoculated. ruminant blood glucose; diet and age interaction; milk solids Submitted on February 26, 1963


PPAR Research ◽  
2010 ◽  
Vol 2010 ◽  
pp. 1-12 ◽  
Author(s):  
Annelies Peeters ◽  
Myriam Baes

Tight control of storage and synthesis of glucose during nutritional transitions is essential to maintain blood glucose levels, a process in which the liver has a central role. PPAR is the master regulator of lipid metabolism during fasting, but evidence is emerging for a role of PPAR in balancing glucose homeostasis as well. By using PPAR ligands and PPAR mice, several crucial genes were shown to be regulated by PPAR in a direct or indirect way. We here review recent evidence that PPAR contributes to the adaptation of hepatic carbohydrate metabolism during the fed-to-fasted or fasted-to-fed transition in rodents.


Author(s):  
Ebahiem Mohammed Alhadi ◽  
Ismail Intisar Alnour ◽  
Salah Bukhari Salah Abulgabar ◽  
Abdalla Mohamed Suleiman Eshag ◽  
Hammad Dahia Salah Basar ◽  
...  

This study aimed to assess the effects of housing condition and watering regimen on some blood parameters during the period May 2018- February 2019. Desert goat Package Cell Volume% (PCV %) were highest during January, February and lowest during May, and August. Goats had the highest (P<0.001) blood Hemoglobin (Hb%) during May and July with very slight fluctuations throughout the seven months of the experimental period. Goats under shade had comparatively higher PCV% and slightly lower Hb% in comparison with those under direct sunlight. Plasma Calcium was low during February and January and rose during December with higher levels during May, June and July. Goat plasma phosphorus concentrations followed an opposite picture being highest (P<0.01) during October, December, and February and lowest (P<0.01) during other months. Plasma Calcium (Ca) and Phosphorus (P) concentrations were slightly (P>0.05) higher for goats under shade compared with those under direct sunlight. The main effects of months on blood metabolites were highly significant (P<0.01). The highest goat blood protein was during, June-July and lowest (P<0.01) during other months. Goat blood albumen levels were highest (P<0.001) for August- September- October and lowest for January- February whereas blood glucose levels were highest (P<0.01) during January- February and with very slight fluctuations throughout the seven months of the experimental period. Blood protein, blood albumin and blood glucose levels were relatively higher (P>0.05) for goats under shade compared with those under direct sunlight. Goats watered everyday had slightly lower blood protein and albumin and slightly higher blood glucose in comparison with goats watered every other day.


Lontara ◽  
2020 ◽  
Vol 1 (2) ◽  
pp. 125-135
Author(s):  
Usman Umar ◽  
Risnawaty Alyah ◽  
Imran Amin

Blood glucose is a very important element in the human body, but if it is deficient or excessive, it can cause chronic disease that can lead to death. To prevent this, it is necessary to monitor cholesterol and blood glucose levels regularly, at this time the tool for measuring blood glucose levels is still an invasive method by taking a blood sample at the fingertip by injuring it. This study aims to develop a non-invasive blood glucose measuring device using a Photoacoustic Spectroscopy sensor in the range of values from a laser pulse source (λ = 650 nm) which can detect glucose signals in the blood. The method of developing this research is by designing a non-invasive measuring instrument and measuring blood glucose levels in male and female participants to create a linearity equation between blood glucose levels and the output voltage from the sensor, then mathematically obtained a polynominal equation to convert the voltage to values. blood glucose level. Validation of measuring instruments designed by comparing invasive measuring instruments as a reference, using the Clarke EGA to determine accuracy based on the classification of values of blood glucose and blood cholesterol levels based on reference. The results of the Clarke EGA analysis show that all measurement data is in Zone A so that the measuring instrument with a photoacoustic sensor can be accepted.


2014 ◽  
Vol 19 (3) ◽  
pp. 195-199 ◽  
Author(s):  
Khushbakht Sultan ◽  
Muhammad Zakir ◽  
Haroon Khan ◽  
Ihsaan Ullah Khan ◽  
Ali Rehman ◽  
...  

Caralluma tuberculata is a cooked food item in Pakistan especially for diabetics. The current study was designed to explore the antidiabetic potential of extract/fractions of Caralluma tuberculata in alloxan-induced diabetic rabbits and its effect on body weight. The crude extract of the plant provoked 24% and 44% antidiabetic action at 25 and 50 mg/kg OP, respectively, after the 24th day of treatment, which was strongly supported by a positive effect on the body weight of animals. On fractionation, pretreatment of the ethyl acetate fraction demonstrated most dominant (25.17% and 34.83%) antidiabetic activity followed by n-hexane (19.33% and 32.76%) and aqueous fractions (16.44% and 22.36%) at 25 and 50 mg/kg OP, respectively, after the 24th day of treatment. The corresponding effect on blood glucose was also observed on body weight of diabetic rabbits. In sum, extract/fractions of the plant showed marked antidiabetic action and thus a provided scientific foundation to the use of the plant as an antidiabetic.


Author(s):  
Askura Nikmah ◽  
Fita Ridhana ◽  
Ilma Fitri ◽  
Hikmah Hikmah

The purpose of this study was to determine the effect of adding probiotic acidifier on the condition of the digestive tract, glucose levels and abdominal fat in broiler chickens. This research conducted in Takengon, Central Aceh District. The parameters observed were the condition of the digestive tract, blood glucose levels and the percentage of abdominal fat. The data obtained were analyzed using analysis of variance (ANOVA). The results showed the use of a 1: 1 mixture of probiotics and acidifier to level 0. The 3% added to the commercial ration which was substituted with 10% fermented feed ingredients (R-KFPA) had no significant effect (P <0.05) on weight and percentage of Gizzard, Gizzard pH and Intestine pH, Intestinal Length, Weight and Percent of Abdominal Fat, as well as blood glucose levels in broiler chickens. Although statistically not significantly different, giving a mixture of probiotics and acidifier at the level of 0.3% (R4) showed a positive effect on decreasing the percentage of abdominal fat from 1.52% (R1) to 1.35% (R4). The blood glucose obtained in this study was slightly higher than normal blood glucose levels in chickens as reported by Swenson weight and percentage of abdominal fat, as well as blood glucose levels of broiler chickens. Although statistically not significantly different, giving a mixture of probiotics and acidifier at the level of 0.3% (R4) showed a positive effect on decreasing the percentage of abdominal fat from 1.52% (R1) to 1.35% (R4). The blood glucose obtained in this study was slightly higher than normal blood glucose levels in chickens as reported by Swenson weight and percentage of abdominal fat, as well as blood glucose levels of broiler chickens. Although statistically not significantly different, giving a mixture of probiotics and acidifier at the level of 0.3% (R4) showed a positive effect on decreasing the percentage of abdominal fat from 1.52% (R1) to 1.35% (R4). The blood glucose obtained in this study was slightly higher than normal blood glucose levels in chickens as reported by Swenson (1993), which ranges from 13 to 27 ml / dl or 130 to 270 mg / dl. It is suspected that this is due to increased digestive activity in chickens so that more nutrients are absorbed.


2020 ◽  
Vol 3 (3a) ◽  
pp. 27-37
Author(s):  
LN UTUME ◽  
PM Ansha ◽  
TA Gav

Monosodium Glutamate (MSG) or glutamate is a commonly used flavour enhancer, naturally found in protein-rich foods; although produced commercially through the fermentation of molasses. MSG is essential in the metabolism of living bodies. The increase in MSG consumption has become a growing concern due to the lack of adequate data on its effects. This study investigates the effects of MSG on weight and blood glucose levels of adult albino rats for an experimental period of eight (8) weeks. Twenty-four (24) albino rats weighing between 48.7 g to 94.6 g were randomly divided into four (4) groups of six (6) rats each: 1 control group and 3 test groups. Test groups were fed and daily doses of MSG dissolved in water (8 g/L, 10 g/L and 15 g/L respectively) were administered orally. The control group were fed on plain water and rat chow (grower’s mash) only. Weekly weights, fasting blood glucose levels of rats were measured, and change in behaviour and exploratory tendencies observed, all through the experimental period. Glycosylated haemoglobin was tested at the end of the experimental period to confirm the weekly blood glucose levels. There was no significant difference in the average weights (P ˃ 0.05). Blood glucose levels maintained a normal range of 4.5 – 5.1 % (good glycemic control) over the experimental period. The study illustrates that Monosodium Glutamate has no adverse effects on weight and blood glucose levels when consumed daily, but not exceeding a 15 g dose. Further research to validate casual inference may be necessary. The consumption of MSG should be in moderation and individuals prone to hypoallergenic reactions should ensure to check product labels for MSG before the consumption of foods. Further research can be carried out using higher doses as well as other metabolic markers in the body to further consolidate empirical data.


2020 ◽  
Author(s):  
Lungwani Muungo

Opuntia stricta (commonly called prickly pear cactus) is a natural plant that grows in some partsof Zambia where its fruits and cladodes are commonly consumed for nutritional and medicinal purposes, including glycaemiccontrol among some patients with diabetes mellitus (DM). There is insufficient evidence whether Opuntia strictaindigenously growing in Zambia possess antidiabetic effects. Aim: To assess in vivo antidiabetic effects of the aqueousextract of Opuntia stricta cladodes in alloxan-induced diabetic mice. Methods: A laboratory-based experimental study wasconducted involving 20 adult Swiss albino mice (Mus musculus) weighing 18-30 g. DM was induced using a singleintraperitoneal dose of alloxan monohydrate 90 mg/kg. Opuntia stricta aqueous extract was administered orally and bloodglucose levels (in mmol/L) monitored daily for 10 days. Results: Alloxan induced a 4- to 5-fold sustained increase in bloodglucose levels at 72 hours after administration in mice. Within a 10-day experimental period, Opuntia stricta cladode aqueousextract (1 mg/kg) significantly reduced blood glucose levels in vivo (from 16.6 ± 1.4 mmol/L, 95% CI: 14.9-18.3 at baselineto 7.5 ± 1.0 mmol/L, 95% CI: 6.2-8.9 at endpoint, p &lt; 0.001, n = 5). Similarly, at a dose of 2 mg/kg, the extractsignificantly reduced blood glucose levels (from 18.7 ± 4.6 mmol/L, 95% CI: 13.0-24.4 at baseline to 6.9 ± 1.7 mmol/L,95% CI: 4.7-9.0 at endpoint, p = 0.001, n = 5). Opuntia stricta cladode aqueous extract attained a greater reduction in bloodglucose levels compared to Glibenclamide 0.25 mg/kg. Opuntia stricta cladode aqueous extract demonstrated a presence ofalkaloids, flavonoids, saponins, sterols, carbohydrates, phenols and tannins. Conclusion: Opuntia stricta cladode fromZambia demonstrates antidiabetic effects to reduce blood glucose levels in vivo.


Electronics ◽  
2019 ◽  
Vol 8 (6) ◽  
pp. 662 ◽  
Author(s):  
Louis WY Liu ◽  
Abhishek Kandwal ◽  
Qingsha Cheng ◽  
Hongjian Shi ◽  
Igbe Tobore ◽  
...  

Non-invasive blood glucose monitoring at microwave frequencies is generally thought to be unreliable in terms of reproducibility of measurements. The failure to reproduce a blood glucose measurement from one experiment to another is in major part due to the unwanted interaction of leaky waves between the ambient environment and the blood glucose measuring device. In this work, we have overcome this problem by simply eliminating the leaky modes through the use of surface electromagnetic waves from a curved Goubau line. In the proposed methodology, a fixed volume of blood-filled skin tissue was first formed by vacuum suction and partially wound with a curved Goubau line which was coated with a 3 mm thick layer of gelatin/glycerin composite. Blood glucose levels were non-invasively determined using a network analyzer. At 4.5 GHz, a near-linear correlation exists between the measured S12 parameters and the blood glucose levels. The measured correlation was highly reproducible and consistent with the measurements obtained using the conventional invasive lancing approach. The findings of this work suggest the feasibility of non-invasive detection of left and right imbalances in the body.


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