scholarly journals Age-Related Changes in Zinc, Copper and Selenium Levels in the Human Prostate

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1403
Author(s):  
Adam Daragó ◽  
Michał Klimczak ◽  
Joanna Stragierowicz ◽  
Mateusz Jobczyk ◽  
Anna Kilanowicz
Keyword(s):  
Prostate Gland ◽  
Essential Elements ◽  
Prostatic Hyperplasia ◽  
Peripheral Part ◽  
Age Related ◽  
Aas Method ◽  
Spectrofluorometric Method ◽  
Low Levels ◽  
Different Parts ◽  
Age Related Changes

Pathophysiological changes in the prostate gland—benign prostatic hyperplasia (BPH) and prostatic adenocarcinoma (PCa)—are closely related to the age of men. In the prostate gland, zinc is of particular importance for its proper functioning, especially with regard to the effects of hormonal disorders. The aim of this study was to evaluate zinc, copper and selenium concentrations in different parts of the prostate gland in relation to age and the nature of pathological changes. Zinc and copper were determined by the AAS method and selenium by the spectrofluorometric method. The concentration of zinc in the central part of the prostate increases with age, and in patients over 36 years it is twice as high as in the peripheral part, where no increase in the level of this element was observed with the age of patients. The above data confirm a possible influence of zinc on the formation of PCa (located mostly in the peripheral part of the prostate, with low levels of zinc) and BPH in the central part where the levels of this element are the highest. The results apparently confirm the disturbed homeostasis of zinc and other essential elements in the etiology of BPH and PCa.

scholarly journals Age-related changes in the innervation of the prostate gland

Organogenesis ◽  
2013 ◽  
Vol 9 (3) ◽  
pp. 206-215 ◽  
Author(s):  
Carl W White ◽  
Jin Han Xie ◽  
Sabatino Ventura
Keyword(s):  
Prostate Gland ◽  
Age Related ◽  
Age Related Changes

Age-related changes in mechanisms accounting for low levels of polyclonally induced immunoglobulin secretion in humans

1985 ◽  
Vol 35 (2) ◽  
pp. 191-199 ◽  
Author(s):  
Demetrios Skias ◽  
Anthony T. Reder ◽  
Margaret Brown Bania ◽  
Jack P. Antel
Keyword(s):  
Immunoglobulin Secretion ◽  
Age Related ◽  
Low Levels ◽  
Age Related Changes

Age-Related Changes of Histological Composition in Established Benign Prostatic Hyperplasia

1996 ◽  
Vol 29 (1) ◽  
pp. 85-89 ◽  
Author(s):  
Manabu Ishigooka ◽  
Shinsuke Hayami ◽  
Yasuhiro Suzuki ◽  
Tohru Hashimoto ◽  
Isoji Sasagawa ◽  
...  
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Prostatic Hyperplasia ◽  
Age Related ◽  
Age Related Changes

scholarly journals The intensity of changes in the activity of enzymes in the tissues of the colon in piglets in different phases of postnatal ontogenesis

2020 ◽  
Vol 194 (3) ◽  
pp. 66-75
Author(s):  
Mayya Terenteva ◽  
Nataliya Mardareva
Keyword(s):  
Colorimetric Method ◽  
Postnatal Period ◽  
Gamma Glutamyl Transferase ◽  
Large White ◽  
Age Related ◽  
White Breed ◽  
Activity Of Enzymes ◽  
Glutamyl Transferase ◽  
Different Parts ◽  
Age Related Changes

Annotation. The purpose is сlarification of patterns of age-related changes in the activity of aspartate aminotransferase (AsAT), alanine aminotransferase (AlAT), gamma-glutamyltransferase (GGT), α-amylase, alkaline phosphatase (AlP) and acid phosphatase (AP ) in tissues of different parts of the cecum in piglets of large white breed, in different phases of nutrition of the early postnatal period of systemic genesis of pig. Methods. Enzyme activities were determined spectrophotometrically (UV-1800) and using a set of reagents from the OJSC Vital Development Corporation, St. Petersburg. The activity of the enzymes AsAT and AlAT was determined by the method of Wrightman and Frenkel, GGT – by the unified colorimetric method at the “end point”. The α-amylase activity was measured by the method of Karavei. The level of AP, AlP was determined by the Bessey – Lowry – Brock method. Results. The degree of structural and chemical changes in the tissues of the cecum in piglets is high in the early phases of the postnatal period, during the first four months of life. They are especially pronounced in transitional phases of nutrition. The most intense age-related changes in metabolic processes in the tissues of the cecum in piglets were revealed between the milk and colostrum and first milk, between the first and second milk, between the third milk and milk-definitive, as well as between the first and second definitive phases. The timing of stabilization of the activity of individual enzymes in the tissues of the cecum is determined. They are detected in piglets in the later phases of feeding. The scientific novelty of the study lies in the fact that the nature and intensity of age-related changes in the activity of aspartate and alanine aminotransferases, gamma-glutamyl transferase, α-amylase, acidic and alkaline phosphatases in tissues of different parts of the cecum in growing piglets were revealed.

Age-related changes of the prostate gland in the senescence-accelerated mouse

The Prostate ◽  
1994 ◽  
Vol 24 (1) ◽  
pp. 24-32 ◽  
Author(s):  
Yoshiki Sugimura ◽  
Masaki Sakurai ◽  
Norio Hayashi ◽  
Atsushi Yamashita ◽  
Juichi Kawamura
Keyword(s):  
Prostate Gland ◽  
Age Related ◽  
Senescence Accelerated Mouse ◽  
Age Related Changes

scholarly journals AGE RELATED CHANGES IN HUMAN PROSTATE GLAND: A MICROSCOPIC STUDY

2016 ◽  
Vol 5 (75) ◽  
pp. 5558-5563
Author(s):  
Lathi Kumari Kalyanikutty Amma ◽  
Usha Devi Keezhathil Bhargavi ◽  
Ammu Sreeparvathi ◽  
Nandagopan S
Keyword(s):  
Microscopic Study ◽  
Prostate Gland ◽  
Human Prostate ◽  
Age Related ◽  
Age Related Changes

AGE-RELATED CHANGES OF ADRENAL ANDROGEN AND ESTROGEN LEVELS IN THE PROSTATIC TISSUE WITH BENIGN PROSTATIC HYPERPLASIA

2009 ◽  
Vol 181 (4S) ◽  
pp. 504-504
Author(s):  
Seiji Arai ◽  
Yasuhiro Shibata ◽  
Yoshimichi Miyashiro ◽  
Bunzo Kashiwagi ◽  
Yukio Tomaru ◽  
...  
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Prostatic Hyperplasia ◽  
Prostatic Tissue ◽  
Adrenal Androgen ◽  
Age Related ◽  
Age Related Changes
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