Age-related changes of the prostate gland in the senescence-accelerated mouse

The Prostate ◽  
1994 ◽  
Vol 24 (1) ◽  
pp. 24-32 ◽  
Author(s):  
Yoshiki Sugimura ◽  
Masaki Sakurai ◽  
Norio Hayashi ◽  
Atsushi Yamashita ◽  
Juichi Kawamura
Keyword(s):  
Prostate Gland ◽  
Age Related ◽  
Senescence Accelerated Mouse ◽  
Age Related Changes

scholarly journals Age-related changes in the innervation of the prostate gland

Organogenesis ◽  
2013 ◽  
Vol 9 (3) ◽  
pp. 206-215 ◽  
Author(s):  
Carl W White ◽  
Jin Han Xie ◽  
Sabatino Ventura
Keyword(s):  
Prostate Gland ◽  
Age Related ◽  
Age Related Changes

Age-related changes in the brain transfer of blood-borne horseradish peroxidase in the hippocampus of senescence-accelerated mouse

1997 ◽  
Vol 93 (3) ◽  
pp. 233-240 ◽  
Author(s):  
M. Ueno ◽  
Ichiro Akiguchi ◽  
Masanori Hosokawa ◽  
Masahiko Shinnou ◽  
Haruhiko Sakamoto ◽  
...  
Keyword(s):  
Horseradish Peroxidase ◽  
Age Related ◽  
The Brain ◽  
Senescence Accelerated Mouse ◽  
Age Related Changes

Age-related changes in transmitter glutamate and NMDA receptor/channels in the brain of senescence-accelerated mouse

1992 ◽  
Vol 137 (2) ◽  
pp. 169-172 ◽  
Author(s):  
Yoshihisa Kitamura ◽  
Xue-Hui Zhao ◽  
Toshio Ohnuki ◽  
Makiko Takei ◽  
Yasuyuki Nomura
Keyword(s):  
Nmda Receptor ◽  
Age Related ◽  
The Brain ◽  
Senescence Accelerated Mouse ◽  
Transmitter Glutamate ◽  
Age Related Changes

Age-Related Changes in Energy Production in Fresh Senescence-Accelerated Mouse Brain Slices as Revealed by Positron Autoradiography

2001 ◽  
Vol 12 (2) ◽  
pp. 78-84 ◽  
Author(s):  
Naoto Omata ◽  
Tetsuhito Murata ◽  
Yasuhisa Fujibayashi ◽  
Atsuo Waki ◽  
Norihiro Sadato ◽  
...  
Keyword(s):  
Mouse Brain ◽  
Energy Production ◽  
Brain Slices ◽  
Age Related ◽  
Senescence Accelerated Mouse ◽  
Age Related Changes

Age-related changes in the oestrous cycle and reproductive hormones in senescence-accelerated mouse

2005 ◽  
Vol 17 (5) ◽  
pp. 507 ◽  
Author(s):  
Ma Yuan ◽  
Zhou Wen-Xia ◽  
Cheng Jun-Ping ◽  
Zhang Yong-Xiang
Keyword(s):  
Substance P ◽  
Luteinising Hormone ◽  
Reproductive Hormones ◽  
Oestrous Cycle ◽  
Reproductive Hormone ◽  
Hormone Levels ◽  
Age Related ◽  
Samp8 Mice ◽  
Senescence Accelerated Mouse ◽  
Age Related Changes

To investigate age-related changes in the oestrous cycle and reproductive hormone levels in senescence-accelerated mouse (SAM), we examined these parameters in 3-, 5-, 7-, 9- and 11-month-old female SAM-prone/8 (SAMP8) and SAM-resistant/1 (SAMR1) strains. Levels of β-endorphin (β-EP) and substance P (SP) in the hypothalamus were also measured. The oestrous cycle and dioestrus of 9-month-old SAMP8 mice were significantly prolonged compared with age-matched SAMR1 mice. Furthermore, the concentration of serum oestradiol was lower and the level of pituitary luteinising hormone was higher in SAMP8 mice compared with SAMR1 mice. This characterises the hypothalamus–pituitary–ovary (HPO) axis of the SAMP8 strain as hypergonadotropic–hypogonad. The levels of β-EP and SP in the SAMP8 hypothalamus were lower than in the SAMR1 hypothalamus. These results indicate that the function of the HPO axis in SAMP8 mice declines early and this may be attributed, in part, to the decline in β-EP and SP concentrations in the hypothalamus.

Erratum to: Age-related changes in the oestrous cycle and reproductive hormones in senescence-accelerated mouse

2009 ◽  
Vol 21 (4) ◽  
pp. 624
Author(s):  
Ma Yuan ◽  
Zhou Wen-Xia ◽  
Cheng Jun-Ping ◽  
Zhang Yong-Xiang
Keyword(s):  
Substance P ◽  
Luteinising Hormone ◽  
Reproductive Hormones ◽  
Oestrous Cycle ◽  
Reproductive Hormone ◽  
Hormone Levels ◽  
Age Related ◽  
Samp8 Mice ◽  
Senescence Accelerated Mouse ◽  
Age Related Changes

To investigate age-related changes in the oestrous cycle and reproductive hormone levels in senescence-accelerated mouse (SAM), we examined these parameters in 3-, 5-, 7-, 9- and 11-month-old female SAM-prone/8 (SAMP8) and SAM-resistant/1 (SAMR1) strains. Levels of �-endorphin (�-EP) and substance P (SP) in the hypothalamus were also measured. The oestrous cycle and dioestrus of 9-month-old SAMP8 mice were significantly prolonged compared with age-matched SAMR1 mice. Furthermore, the concentration of serum oestradiol was lower and the level of pituitary luteinising hormone was higher in SAMP8 mice compared with SAMR1 mice. This characterises the hypothalamus.pituitary.ovary (HPO) axis of the SAMP8 strain as hypergonadotropic.hypogonad. The levels of �-EP and SP in the SAMP8 hypothalamus were lower than in the SAMR1 hypothalamus. These results indicate that the function of the HPO axis in SAMP8 mice declines early and this may be attributed, in part, to the decline in �-EP and SP concentrations in the hypothalamus.

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