scholarly journals Heterogeneity of Associations between Total and Types of Fish Intake and the Incidence of Type 2 Diabetes: Federated Meta-Analysis of 28 Prospective Studies Including 956,122 Participants

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1223
Author(s):  
Silvia Pastorino ◽  
Tom Bishop ◽  
Stephen J. Sharp ◽  
Matthew Pearce ◽  
Tasnime Akbaraly ◽  
...  

The association between fish consumption and new-onset type 2 diabetes is inconsistent and differs according to geographical location. We examined the association between the total and types of fish consumption and type 2 diabetes using individual participant data from 28 prospective cohort studies from the Americas (6), Europe (15), the Western Pacific (6), and the Eastern Mediterranean (1) comprising 956,122 participants and 48,084 cases of incident type 2 diabetes. Incidence rate ratios (IRRs) for associations of total fish, shellfish, fatty, lean, fried, freshwater, and saltwater fish intake and type 2 diabetes were derived for each study, adjusting for a consistent set of confounders and combined across studies using random-effects meta-analysis. We stratified all analyses by sex due to observed interaction (p = 0.002) on the association between fish and type 2 diabetes. In women, for each 100 g/week higher intake the IRRs (95% CIs) of type 2 diabetes were 1.02 (1.01–1.03, I2 = 61%) for total fish, 1.04 (1.01–1.07, I2 = 46%) for fatty fish, and 1.02 (1.00–1.04, I2 = 33%) for lean fish. In men, all associations were null. In women, we observed variation by geographical location: IRRs for total fish were 1.03 (1.02–1.04, I2 = 0%) in the Americas and null in other regions. In conclusion, we found evidence of a neutral association between total fish intake and type 2 diabetes in men, but there was a modest positive association among women with heterogeneity across studies, which was partly explained by geographical location and types of fish intake. Future research should investigate the role of cooking methods, accompanying foods and environmental pollutants, but meanwhile, existing dietary regional, national, or international guidelines should continue to guide fish consumption within overall healthy dietary patterns.

2020 ◽  
Vol 46 (5) ◽  
pp. 345-352 ◽  
Author(s):  
Xiu Yang ◽  
Yuqian Li ◽  
Chongjian Wang ◽  
Zhenxing Mao ◽  
Wen Zhou ◽  
...  

2015 ◽  
Vol 56 (2) ◽  
pp. 843-852 ◽  
Author(s):  
Alice Wallin ◽  
Daniela Di Giuseppe ◽  
Nicola Orsini ◽  
Agneta Åkesson ◽  
Nita G. Forouhi ◽  
...  

FACETS ◽  
2017 ◽  
Vol 2 (2) ◽  
pp. 795-818 ◽  
Author(s):  
Lesya Marushka ◽  
Malek Batal ◽  
Donald Sharp ◽  
Harold Schwartz ◽  
Amy Ing ◽  
...  

Consumption of fish and n-3 fatty acids (n-3 FAs) has been postulated to prevent type 2 diabetes (T2D).Objective: To explore the association between self-reported T2D and fish consumption, dietary n-3 FAs, and persistent organic pollutants (POP) intake in a regionally representative sample of First Nations (FNs) in Manitoba.Design: Data from the cross-sectional First Nations Food, Nutrition and Environment Study (FNFNES) collected from 706 members of 8 Manitoba FNs in 2010 were used. Household interviews were used to collect social and lifestyle data. The consumption of fish was estimated using a traditional food frequency questionnaire. Fish samples were analyzed for the presence of POP. Multiple logistic regression models adjusted for potential risk factors for T2D were developed.Results: A negative, dose–response relationship was found between fish intake and self-reported T2D. Fish consumptions of 2–3 portions per month and ≥1/week were inversely associated with T2D with odds ratio (OR) values of 0.51 (95% CI: 0.28–0.91) and 0.40 (95% CI: 0.19–0.82), respectively, compared with no fish intake. Similarly, intake of n-3 FAs was negatively associated with T2D (OR = 0.48 (95% CI: 0.30–0.77). Dietary POP intake was not associated with T2D.Conclusion: These findings suggest that the consumption of traditionally harvested fish may have a beneficial effect on T2D in Manitoba FNs.


Diabetes Care ◽  
2012 ◽  
Vol 35 (4) ◽  
pp. 918-929 ◽  
Author(s):  
A. Wallin ◽  
D. Di Giuseppe ◽  
N. Orsini ◽  
P. S. Patel ◽  
N. G. Forouhi ◽  
...  

2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Mingling Chen ◽  
Gebresilasea Ukke ◽  
Surbhi Sood ◽  
Christie Bennett ◽  
Mahnaz Khomami ◽  
...  

Abstract Background The risk of type 2 diabetes varies by ethnicity, but ethnic differences in response to lifestyle interventions for diabetes prevention remain unclear. This systematic review and meta-analysis aimed to assess differences in the effects of lifestyle interventions on diabetes incidence, glycemic outcomes and anthropometric measures between ethnic groups. Methods MEDLINE, EMBASE, Pubmed, CINAHL, PsycInfo and EBM Reviews were searched (to June 2020) with no language restriction for randomized and non-randomized controlled trials on lifestyle interventions involving diet and/or physical activity in adults at risk of type 2 diabetes. Ethnicity was categorized into European, South Asian, Other Asian, Middle Eastern, Latin American and African groups based on the World Bank regions. Risk ratios for diabetes incidence and mean differences for glycemic outcomes (fasting glucose, 2-h glucose, HbA1c) and anthropometric measures (weight, BMI, waist circumference) were pooled using random-effects meta-analysis. Results Sixty articles representing 43 studies (18,691 participants) were included in meta-analyses. Overall, lifestyle interventions resulted in significant improvement in diabetes incidence, glycemic outcomes and anthropometric measures compared with controls (all P<0.01). Significant subgroup differences by ethnicity were found for 2-h glucose, weight, BMI and waist circumference (all P<0.05) but not for diabetes incidence, fasting glucose and HbA1c (all P>0.05). Conclusions Lifestyle interventions are similarly effective in reducing diabetes incidence, fasting glucose and HbA1c for all ethnic groups, however, 2-h glucose and anthropometric outcomes should be optimized in certain ethnic groups. Key messages Lifestyle intervention is likely effective in preventing the progression to type 2 diabetes equally across all ethnic groups.


2011 ◽  
Vol 40 (3) ◽  
pp. 804-818 ◽  
Author(s):  
E. Agardh ◽  
P. Allebeck ◽  
J. Hallqvist ◽  
T. Moradi ◽  
A. Sidorchuk

2014 ◽  
Vol 40 (6) ◽  
pp. 731-744 ◽  
Author(s):  
Lisa L. Sumlin ◽  
Theresa J. Garcia ◽  
Sharon A. Brown ◽  
Mary A. Winter ◽  
Alexandra A. García ◽  
...  

Purpose Depression affects millions of people worldwide and is prevalent among those with diabetes. The purpose of this review was to synthesize recent research on depression and adherence to dietary and physical activity recommendations in persons with type 2 diabetes (T2DM). Methods This systematic review is a subanalysis of an NIH-funded model-testing meta-analysis. Thirteen electronic databases were searched using terms: depression, adherence, T2DM, diabetes. Selected studies: were reported in English between 2000 and 2012, focused on adults with T2DM, and measured depression and dietary and/or physical activity adherence. Results Twenty-seven studies involving 7266 participants were selected; participants were 54% female and 62 years of age, on average. When reported, depression prevalence in study samples ranged from 4.5% to 74%. Six intervention studies targeted diabetes treatment, with or without depression treatment; no studies focused solely on treating depression. Twenty-one descriptive studies examined relationships between depression and diet/physical activity adherence, finding a negative association. Only 2 of the 6 intervention studies examined this relationship; findings were inconsistent. Conclusion Depression was associated with lower adherence to diabetes self-care, as evidenced primarily by descriptive studies; results of intervention studies were conflicting. Future research should focus on the effects of treating depression on diabetes health outcomes.


2011 ◽  
Vol 96 (6) ◽  
pp. 1654-1663 ◽  
Author(s):  
Robert H. Eckel ◽  
Steven E. Kahn ◽  
Ele Ferrannini ◽  
Allison B. Goldfine ◽  
David M. Nathan ◽  
...  

Objective: This report examines what is known about the relationship between obesity and type 2 diabetes and how future research in these areas might be directed to benefit prevention, interventions, and overall patient care. Research Design and Methods: An international working group of 32 experts in the pathophysiology, genetics, clinical trials, and clinical care of obesity and/or type 2 diabetes participated in a conference held on 6–7 January 2011 and cosponsored by The Endocrine Society, the American Diabetes Association, and the European Association for the Study of Diabetes. A writing group comprising eight participants subsequently prepared this summary and recommendations. Participants reviewed and discussed published literature and their own unpublished data. Results: The writing group unanimously supported the summary and recommendations as representing the working group's majority or unanimous opinions. Conclusions: The major questions linking obesity to type 2 diabetes that need to be addressed by combined basic, clinical, and population-based scientific approaches include the following: 1) Why do not all patients with obesity develop type 2 diabetes? 2) Through what mechanisms do obesity and insulin resistance contribute to β-cell decompensation, and if/when obesity prevention ensues, how much reduction in type 2 diabetes incidence will follow? 3) How does the duration of type 2 diabetes relate to the benefits of weight reduction by lifestyle, weight-loss drugs, and/or bariatric surgery on β-cell function and glycemia? 4) What is necessary for regulatory approval of medications and possibly surgical approaches for preventing type 2 diabetes in patients with obesity? Improved understanding of how obesity relates to type 2 diabetes may help advance effective and cost-effective interventions for both conditions, including more tailored therapy. To expedite this process, we recommend further investigation into the pathogenesis of these coexistent conditions and innovative approaches to their pharmacological and surgical management.


2020 ◽  
Vol 3 ◽  
pp. 1-16
Author(s):  
Ozge Olbeci ◽  
Aycan Celik ◽  
Russell Jone

Background: Type 2 diabetes mellitus (T2DM) is among the leading causes of serious mortality and health burden globally. Exercise is one of the commonly suggested preventions/ interventions for T2DM. However, many adults with T2DM are not achieving the recommended levels of physical activity. The objective of this systematic review is to investigate the barriers and facilitators to physical activity among people living with type 2 diabetes. Methods/Design: This review will be undertaken using the Preferred Reporting Items and Meta-analysis (PRISMA). The database search will be performed in MEDLINE, CINAHL, PubMed, and Web of Science. Studies included will report primary data (qualitative and quantitative) on people with T2DM (18 and over years of age). The review will be limited in English published between 2009 and 2020. A study design describing reasons for barriers, facilitators or both of physical activity among people with T2DM will be included. The risk of bias will be evaluated with Mixed-Methods Appraisal Tool (MMAT). Data synthesis will be conducted with narrative synthesis for quantitative studies, and thematic synthesis for qualitative studies followed by a mix-method synthesis to combine the previous synthesis. Discussion: This review will provide evidence for better understanding the facilitators and barriers to physical activity among people with T2DM. This information will also guide future research and support the development of the intervention to expand and increase facilitator factors determined by people with T2DM.    


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