scholarly journals Effect of Maternal Nutritional Status and Mode of Delivery on Zinc and Iron Stores at Birth

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 860
Author(s):  
Oraporn Dumrongwongsiri ◽  
Pattanee Winichagoon ◽  
Nalinee Chongviriyaphan ◽  
Umaporn Suthutvoravut ◽  
Veit Grote ◽  
...  
Keyword(s):  
Nutritional Status ◽  
Cord Blood ◽  
Mode Of Delivery ◽  
Serum Zinc ◽  
Maternal Blood ◽  
Second Trimester ◽  
Food Frequency ◽  
Iron Stores ◽  
Maternal Nutritional Status ◽  
Blood Zinc

Zinc and iron deficiencies among infants aged under 6 months may be related with nutrient store at birth. This study aimed to investigate the association between zinc and iron stores at birth with maternal nutritional status and intakes during pregnancy. 117 pregnant women were enrolled at the end of second trimester and followed until delivery. Clinical data during pregnancy, including pre-pregnancy body mass index (BMI) and at parturition were collected from medical record. Zinc and iron intakes were estimated from a food frequency questionnaire. Serum zinc and ferritin were determined in maternal blood at enrollment and cord blood. Mean cord blood zinc and ferritin were 10.8 ± 2.6 µmol/L and 176 ± 75.6 µg/L, respectively. Cord blood zinc was associated with pre-pregnancy BMI (adj. ß 0.150; p = 0.023) and serum zinc (adj. ß 0.115; p = 0.023). Cord blood ferritin was associated with pre-pregnancy BMI (adj. ß −5.231; p = 0.009). Cord blood zinc and ferritin were significantly higher among those having vaginal delivery compared to cesarean delivery (adj. ß 1.376; p = 0.007 and 32.959; p = 0.028, respectively). Maternal nutritional status and mode of delivery were significantly associated with zinc and iron stores at birth. Nutrition during preconception and pregnancy should be ensured to build adequate stores of nutrients for infants.

scholarly journals Hubungan indeks massa tubuh (IMT) awal kehamilan dengan luaran maternal neonatal

e-CliniC ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Rut C.F. Weku ◽  
John J.E. Wantania ◽  
Joice M.M Sondakh
Keyword(s):  
Nutritional Status ◽  
Early Pregnancy ◽  
Mode Of Delivery ◽  
Cross Sectional Study ◽  
Neonatal Outcomes ◽  
Sectio Caesarea ◽  
Cross Sectional ◽  
Maternal Nutritional Status ◽  
Maternal And Neonatal Outcomes ◽  
The Relationship

Abstract: Maternal nutritional status is very important for the outcomes of pregnancy. The best indicator for measuring the nutritional status is Body Mass Index (BMI). Abnormal BMI in early pregnancy is associated with various complications for the mother as well as the baby. This study was aimed to obtain the relationship between BMI in early pregnancy and maternal and neonatal outcomes. This was a retrospective analytical study with a cross sectional study. The results showed that there was a siginificant relationship between BMI in early pregnancy and blood pressure (p=0.049), but there was no significant relationship between BMI in early pregnancy and mode of delivery (p=0.067), birth (p=0.100), infant mortality (0.377), and APGAR score (p=0.100). Conclusion: Pregnant woman with BMI ≥25 kg/m2 had a risk of hypertension in pregnancy and a sectio caesarea in delivery; and the baby showed a tendency of low birth weight, risk to death, and asphyxia.Keywords: BMI, pregnancy and maternal neonatal outcomes Abstrak: Status gizi ibu sangat penting terhadap luaran kehamilan. Indikator untuk mengukur status gizi ialah Indeks Massa Tubuh (IMT). Ibu dengan IMT awal kehamilan yang tidak dalam batas normal berkaitan dengan berbagai komplikasi baik terhadap ibu maupun bayi. Penelitian ini bertujuan untuk mengetahui hubungan antara IMT awal kehamilan dengan luaran maternal neonatal. Jenis penelitian ialah analitik-retrospektif dengan desain potong lintang. Hasil penelitian mendapatkan bahwa IMT awal kehamilan berhubungan bermakna dengan tekanan darah (p=0,049), tetapi tidak ditemukan hubungan bermakna antara IMT awal kehamilan dengan cara persalinan (p=0,069), berat badan lahir bayi (p=1,000), kematian bayi (p=0,377), dan APGAR skor (p=1,000). Simpulan: Ibu dengan IMT≥25 kg/m2 berisiko mengalami hipertensi dalam kehamilan, cenderung menjalani persalinan dengan seksio sesarea, dan bayinya cenderung memiliki berat badan lahir rendah, mengalami kematian, dan asfiksia. Kata kunci: IMT, kehamilan dan luaran maternal neonatal.

scholarly journals Comparison of maternal serum and neonatal cord blood levels of zinc in relation to birth weight and period of gestation

2021 ◽  
Vol 8 (8) ◽  
pp. 1349
Author(s):  
Shabbeer Ahmed ◽  
Avula Kanthi Sagar
Keyword(s):  
Birth Weight ◽  
Cord Blood ◽  
Zinc Deficiency ◽  
Serum Zinc ◽  
Maternal Serum ◽  
Blood Levels ◽  
P Value ◽  
Zinc Levels ◽  
Blood Zinc ◽  
Serum Zinc Levels

Background: Women are at increased risk of zinc deficiency during pregnancy because of high fetal requirements for zinc. Severe maternal zinc deficiency has been associated with poor fetal growth, spontaneous abortion and congenital malformations (i.e., anencephaly), whereas milder forms of zinc deficiency have been associated with low birth weight (LBW), intrauterine growth retardation, and preterm delivery. However, the research relating maternal zinc status and birth weight has not produced consistent results. This study has been undertaken to confirm the association between maternal serum zinc concentration and birth weight and period of gestation in setting like India.Methods: A total of 100 new-borns were included and divided into two groups, the ‘study group’ had babies with birth weight <2.5 kg and control group’ with babies >2.5 kg birth weight. Cord blood from the new-borns and serum samples of mothers were collected and the zinc levels were measured.Results: The correlation of cord blood and the maternal serum zinc levels were assessed in relation to birth weight and the gestational age. The results were compared between the two groups. The difference in values between the two groups was statistically significant, maternal serum zinc levels and birth weight (84.78±21.62 vs 66.04±18.66) (‘P’ value 0.04), cord blood zinc levels and birth weight (98.44±22.59 vs 79.78±19.54) (‘P’ value <0.001). The maternal serum and cord blood zinc was compared between the preterm and term; the results were statistically significant.Conclusions: The maternal and cord blood levels of zinc are correlated well with the birth weight and the gestational age at delivery. Supplementation of zinc during gestation might help reduce the incidence of IUGR and the risk of prematurity.

Influence of maternal nutritional status on mode of delivery and asphyxia neonatorum

1992 ◽  
Vol 59 (3) ◽  
pp. 325-329
Author(s):  
N. Thilothammal ◽  
K. G. Kamala ◽  
T. P. Ashok ◽  
S. Ramanujam ◽  
K. Nedunchelian ◽  
...  
Keyword(s):  
Nutritional Status ◽  
Mode Of Delivery ◽  
Asphyxia Neonatorum ◽  
Maternal Nutritional Status

Serum zinc and copper levels in the maternal blood and cord blood of neonates

2001 ◽  
Vol 68 (6) ◽  
pp. 523-526 ◽  
Author(s):  
A. S. M. Iqbal ◽  
Md. Shahidullah ◽  
Md. Nurul Islam ◽  
Sohela Akhter ◽  
Shahanara Banu
Keyword(s):  
Cord Blood ◽  
Serum Zinc ◽  
Maternal Blood

scholarly journals Maternal iron absorption and iron transfer to the fetus during pregnancy in normal- weight and overweight/obese women

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Nicole U. Stoffel ◽  
Michael B. Zimmermann ◽  
Christophe Zeder ◽  
Katharina Quack Loetscher ◽  
Ana Carla Cepeda Lopze ◽  
...  
Keyword(s):  
Cord Blood ◽  
Weight Status ◽  
Iron Absorption ◽  
Maternal Blood ◽  
Normal Weight ◽  
Cord Blood Sample ◽  
Obese Women ◽  
Iron Transfer ◽  
Iron Stores ◽  
Iron Supply

AbstractOverweight/obesity (owob) causes low-grad systemic inflammation and thereby an up-regulation of hepcidin and a reduction in fractional iron absorption (FIA) even with low iron stores. Pregnancy increases iron needs because of the expansion of maternal blood volume and fetal needs. It is unclear to what extent owob pregnancy influences FIA, iron supply of the fetus and risk of iron deficiency. Therefore, the main aim of this study was to determine the effect of maternal owob on iron absorption during pregnancy and on the iron transfer to the fetus. Secondary objectives were to investigate the development of hepcidin, plasma ferritin and inflammatory markers over the course of pregnancy dependent on weight status. In this multicenter case-control study we included 44 normal weight (nw) and 36 owob women around pregnancy week (PW) 12. We administered 57Fe or 58Fe labeled FeSO4 to women during the 2nd and 3rd trimester of pregnancy. We measured FIA determining erythrocyte incorporation of iron stable isotopes 14 days after administration. From PW 12 until PW 36 iron-, inflammation and hepcidin were monitored. Iron transfer to the fetus was determined as iron stable isotope concentration in cord blood. Sample analysis is currently ongoing, all results will be available in October. Subject characteristics in PW 12 for the nw (n = 26) and owob (n = 10) were: mean BMI: 21.4 ± 2.2 and 36.7 ± 6.8 kg/m2, mean hemoglobin: 12.4 ± 1.2 and 12.4 ± 0.9 g/dL and median plasma ferritin: 41.3 (29.6–83.6) and 61.6 (24.3–119.0) μg/L. Preliminary results indicate FIA increased by 2.4 fold in the nw and by 1.3 fold in the owob women between the 2nd and the 3rd trimester of pregnancy. Iron stores decreased in both groups over the course of pregnancy. Hepcidin was still significantly higher in the owob women in the 3rd trimester. Inflammation tended to be higher in owob women throughout pregnancy. Iron isotopes were highly detectable in cord blood. The 58Fe:57Fe-ratio determined in cord blood corresponded to the 58Fe:57Fe-ratio determined in the mother in the 3rd trimester. Thus, in owob women, the increase in FIA throughout pregnancy to support iron needs of mother and fetus is blunted compared to nw women. This is consistent with elevated hepcidin in the 3rd trimester and higher inflammation throughout pregnancy. Thus, even though iron demands are strongly increased, owob may prohibit an adequate iron supply to the expecting mother and the fetus due to persistent subclinical inflammation.

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