scholarly journals Associations of Dietary Intake on Biological Markers of Inflammation in Children and Adolescents: A Systematic Review

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 356
Author(s):  
Melissa Bujtor ◽  
Anne Turner ◽  
Susan Torres ◽  
Laura Esteban-Gonzalo ◽  
Carmine Pariante ◽  
...  
Keyword(s):  
Systematic Review ◽  
Dietary Intake ◽  
Children And Adolescents ◽  
Biological Markers ◽  
Inflammatory Biomarkers ◽  
Low Grade ◽  
Food Groups ◽  
Markers Of Inflammation ◽  
Promising Therapeutic Approach ◽  
Low Grade Inflammation

Background: In children and adolescents, chronic low-grade inflammation has been implicated in the pathogenesis of co- and multi-morbid conditions to mental health disorders. Diet quality is a potential mechanism of action that can exacerbate or ameliorate low-grade inflammation; however, the exact way dietary intake can regulate the immune response in children and adolescents is still to be fully understood. Methods: Studies that measured dietary intake (patterns of diet, indices, food groups, nutrients) and any inflammatory biomarkers in children and adolescents aged 2 to19 years and published until November 2020 were included in this systematic review, and were selected in line with PRISMA guidelines through the following databases: Academic Search Complete, CINAHL, Global Health, Medline COMPLETE and Web of Science–Core Collection. A total of 53 articles were identified. Results: Results show that adequate adherence to healthful dietary patterns such as the Mediterranean diet, or food groups such as vegetables and fruit, or macro/micro nutrients such as fibre or vitamin C and E, are associated with decreased levels of pro-inflammatory biomarkers, mainly c-reactive protein (CRP), interleukin-6 (IL-6) and tumour necrosis factor-alpha (TNF-α), whereas adherence to a Western dietary pattern, as well as intake of food groups such as added sugars, macro-nutrients such as saturated fatty acids or ultra-processed foods, is associated with higher levels of the same pro-inflammatory biomarkers. Conclusions: This is the first systematic review examining dietary intake and biological markers of inflammation in both children and adolescents. A good quality diet, high in vegetable and fruit intake, wholegrains, fibre and healthy fats ameliorates low-grade inflammation, and therefore represents a promising therapeutic approach, as well as an important element for disease prevention in both children and adolescents.

scholarly journals Associations of Dietary Intake on Biological Markers of Inflammation in Children and Adolescents: A Systematic Review

2021 ◽  
Vol 131 ◽  
pp. 105459
Author(s):  
Melissa Bujtor ◽  
Anne I Turner ◽  
Susan J Torres ◽  
Laura Esteban-Gonzalo ◽  
Carmine M. Pariante ◽  
...  
Keyword(s):  
Systematic Review ◽  
Dietary Intake ◽  
Children And Adolescents ◽  
Biological Markers ◽  
Markers Of Inflammation

scholarly journals The Role of Circulating Lycopene in Low-Grade Chronic Inflammation: A Systematic Review of the Literature

Molecules ◽  
2020 ◽  
Vol 25 (19) ◽  
pp. 4378
Author(s):  
Hidde P. van Steenwijk ◽  
Aalt Bast ◽  
Alie de Boer
Keyword(s):  
Systematic Review ◽  
Chronic Inflammation ◽  
Intervention Studies ◽  
Low Grade ◽  
Inclusion Criteria ◽  
Cross Sectional ◽  
Markers Of Inflammation ◽  
The Impact ◽  
Low Grade Inflammation

Background and aims: In recent years, it has become clear that low-grade chronic inflammation is involved in the onset and progression of many non-communicable diseases. Many studies have investigated the association between inflammation and lycopene, however, results have been inconsistent. This systematic review aims to determine the impact of circulating lycopene on inflammation and to investigate the effect of consuming tomato products and/or lycopene supplements on markers of inflammation. Methods: Eligible studies, published before March 2020, were identified from PubMed, EBSCOhost and ScienceDirect. Human studies published in English, that evaluated the effect of circulating lycopene in relation to inflammation biomarkers were screened and included. Studies assessing lycopene intake or general intake of carotenoids/antioxidants without measuring circulating lycopene, as well as those not reporting inflammation biomarkers as outcomes, were excluded. Results: Out of 80 publications identified and screened, 35 met the inclusion criteria. Results from 18 cross-sectional studies suggest that lycopene levels are adversely affected during inflammation and homeostatic imbalance. Most of the 17 included intervention studies reported increased circulating lycopene levels after tomato/lycopene supplementation, but almost no changes in inflammation biomarkers were observed. Conclusions: There is little evidence that increasing tomato intake or lycopene supplementation diminuates this inflammation. However, depletion of lycopene may be one of the first signs of low-grade inflammation. The available data thereby imply that it is beneficial to consume lycopene-rich foods occasionally to stay healthy and keep circulating lycopene at a basal level.

scholarly journals SARS-CoV-2 and Obesity: “CoVesity”—a Pandemic Within a Pandemic

2021 ◽  
Author(s):  
Kimberley Zakka ◽  
◽  
Swathikan Chidambaram ◽  
Sami Mansour ◽  
Kamal Mahawar ◽  
...  
Keyword(s):  
Systematic Review ◽  
Risk Factor ◽  
Viral Load ◽  
Respiratory Failure ◽  
Health Outcomes ◽  
Severe Disease ◽  
Vulnerable Population ◽  
Low Grade ◽  
Obesity Management ◽  
Low Grade Inflammation

AbstractIndividuals who are overweight or suffering from obesity are in a chronic state of low-grade inflammation, making them particularly susceptible to developing severe forms of respiratory failure. Studies conducted in past pandemics link obesity with worse health outcomes. This population is thus of particular concern within the context of the COVID-19 pandemic, considering the cessation of obesity management services. This systematic review highlights [1] the reciprocal link between the obesity and COVID-19 pandemics, [2] obesity as a risk factor for more severe disease in past pandemics, [3] potential mechanisms that make individual’s suffering from obesity more susceptible to severe disease and higher viral load, and [4] the need to safely resume bariatric services as recommended by expert guidelines, in order to mitigate the health outcomes of an already vulnerable population.

Relative validity of FFQ to assess food items, energy, macronutrient and micronutrient intake in children and adolescents: a systematic review with meta-analysis

2020 ◽  
pp. 1-27 ◽  
Author(s):  
Luisa Saravia ◽  
Maria L. Miguel-Berges ◽  
Iris Iglesia ◽  
Marcus V. Nascimento-Ferreira ◽  
Guillermo Perdomo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Dietary Intake ◽  
Children And Adolescents ◽  
Meta Analysis ◽  
Dietary Assessment ◽  
Assessment Method ◽  
Nutritional Epidemiology ◽  
Healthy Children ◽  
Relative Validity ◽  
Dietary Assessment Method

Abstract FFQ are one of the most widely used tools of research into nutritional epidemiology, and many studies have been conducted in several countries using this dietary assessment method. The present study aimed to evaluate the relative validity of FFQ, in comparison with other methods, in assessing dietary intake of children and adolescents, through a systematic review. Four electronic databases (Embase, PubMed, Scopus and Web of Science) found sixty-seven articles, which met the inclusion criteria (healthy children and adolescents from 3 to 18 years of age; journal articles written in English, Spanish and Portuguese between 1988 and March 2019; results showing the comparison between the FFQ with other methods of assessment of dietary intake). The articles were analysed by two independent reviewers. A meta-analysis was conducted using correlation coefficients as estimate effects between the FFQ and the reference standard method. Subgroup analysis and meta-regression were performed to identify the probable source of heterogeneity. In fifty-five of the sixty-seven studies, a single dietary assessment method was used to evaluate the FFQ; nine combined the two methods and three used three reference methods. The most widely used reference method was the 24-h recall, followed by the food record. The overall relative validity of the FFQ to estimate energy, macronutrient, certain micronutrient and certain food item intakes in children and adolescents may be considered weak. The study protocol was registered in PROSPERO under number CRD42016038706.

Systematic Review on Dietary Intake and Metabolic Syndrome in Children and Adolescents

2012 ◽  
Vol 3 (6) ◽  
pp. 162-168
Author(s):  
Mojgan Nourian ◽  
◽  
Zaitun Yassin ◽  
Mohd Nasir Mohd Taib ◽  
Fahimeh Haghighatdoost ◽  
...  
Keyword(s):  
Systematic Review ◽  
Metabolic Syndrome ◽  
Dietary Intake ◽  
Children And Adolescents

scholarly journals Dietary Pattern and Macronutrients Profile on the Variation of Inflammatory Biomarkers: Scientific Update

2018 ◽  
Vol 2018 ◽  
pp. 1-18 ◽  
Author(s):  
Brenda Kelly Souza Silveira ◽  
Thatianne Moreira Silva Oliveira ◽  
Patrícia Amaro Andrade ◽  
Helen Hermana Miranda Hermsdorff ◽  
Carla de Oliveira Barbosa Rosa ◽  
...  
Keyword(s):  
Dietary Pattern ◽  
Saturated Fat ◽  
Inflammatory Biomarkers ◽  
Low Grade ◽  
Omega 3 ◽  
Cross Sectional ◽  
Positive Effects ◽  
Inflammatory State ◽  
Fat Diets ◽  
Low Grade Inflammation

It is known that the dietary pattern and macronutrients profile may influence the expression and secretion of inflammatory biomarkers, and the low-grade inflammation is associated with the manifestation of noncommunicable chronic diseases. Therefore, this review aimed to present and discuss the role of dietary patterns and macronutrients on the variation of inflammatory markers related to NCD risk. Scientific evidences within the last five years based on clinical trials, case-controls, cohorts, and cross-sectional studies indicate that normocaloric, carbohydrate-moderated, low-glycemic index, protein-moderated, monounsaturated and polyunsaturated fatty acid-rich, omega-3, and low-saturated fat diets display positive effects on the inflammatory state, both in healthy individuals and in those with cardiovascular risk, although the second group seems to benefit more from changes in the dietary profile.

scholarly journals Association of Common Variants of UCP2 Gene With Low-Grade Inflammation in Swedish Children and Adolescents; The European Youth Heart Study

2009 ◽  
Vol 66 (3) ◽  
pp. 350-354 ◽  
Author(s):  
Idoia Labayen ◽  
Francisco B Ortega ◽  
Michael Sjöström ◽  
Torbjörn K Nilsson ◽  
Lovisa A Olsson ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Low Grade ◽  
Common Variants ◽  
Heart Study ◽  
Ucp2 Gene ◽  
European Youth Heart Study ◽  
Low Grade Inflammation ◽  
European Youth

T- wave axis deviation is associated with biomarkers of low-grade inflammation

2015 ◽  
Vol 114 (12) ◽  
pp. 1199-1206 ◽  
Author(s):  
Marialaura Bonaccio ◽  
Augusto Di Castelnuovo ◽  
Livia Rago ◽  
Amalia De Curtis ◽  
Deodato Assanelli ◽  
...  
Keyword(s):  
Low Grade ◽  
Axis Deviation ◽  
C Reactive Protein ◽  
Cvd Risk ◽  
Cross Sectional ◽  
Reactive Protein ◽  
T Wave ◽  
Markers Of Inflammation ◽  
T Wave Axis ◽  
Low Grade Inflammation

SummaryT-wave axis deviation (TDev) may help identifying subjects at risk for major cardiac events and mortality, but the pathogenesis of TDev is not well established; in particular, the possible association between TDev and inflammation is unexplored and unknown. We aimed at investigating the association between low-grade inflammation and TDev abnormalities by conducting a cross-sectional analysis on 17,507 subjects apparently free from coronary heart and haematological diseases enrolled in the MOLI-SANI study. TDev was measured from a standard 12-lead resting electrocardiogram. High sensitivity (Hs) C-reactive protein (CRP), leukocyte (WBC) and platelet counts, neutrophil or granulocyte to lymphocyte ratios were used as markers of inflammation. In multivariable model subjects reporting high CRP levels had higher odds of having borderline and abnormal TDev (OR=1.70; 95 %CI: 1.53–1.90 and OR=1.72; 95 %CI: 1.23–2.41, respectively); the association was still significant, although reduced, after controlling for body mass index (OR=1.17; 95 %CI: 1.05–1.32, for borderline and OR=1.46; 95 %CI: 1.03–2.08, for abnormal). Similarly, higher neutrophil or granulocyte to lymphocyte ratios were associated with increased odds of having abnormal TDev. Neither platelet nor leukocyte counts were associated with abnormal TDev. The relationship between CRP with TDev abnormalities was significantly stronger in men, in non- obese or normotensive individuals, and in those without metabolic syndrome. In conclusion, C-reactive protein and some cellular biomarkers of inflammation such as granulocyte or neutrophil to lymphocyte ratios were independently associated with abnormal TDev, especially in subjects at low CVD risk. These results suggest that a low-grade inflammation likely contributes to the pathogenesis of T- wave axis deviation.

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