scholarly journals The Role of Zinc in Selected Female Reproductive System Disorders

Nutrients ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2464
Author(s):  
Marzenna Nasiadek ◽  
Joanna Stragierowicz ◽  
Michał Klimczak ◽  
Anna Kilanowicz
Keyword(s):  
Reproductive System ◽  
Zinc Supplementation ◽  
Polycystic Ovary ◽  
Immunological Response ◽  
The Body ◽  
Female Reproductive System ◽  
Randomized Controlled Studies ◽  
Potential Impact ◽  
Post Menopausal

Zinc is an essential microelement that plays many important functions in the body. It is crucial for the regulation of cell growth, hormone release, immunological response and reproduction. This review focuses on its importance in the reproductive system of women of reproductive and postmenopausal ages, not including its well described role in pregnancy. Only recently, attention has been drawn to the potential role of zinc in polycystic ovary syndrome (PCOS), dysmenorrhea, or endometriosis. This review is mainly based on 36 randomized, controlled studies on reproductive, pre- and post-menopausal populations of women and on research trying to explain the potential impact of zinc and its supplementation in the etiology of selected female reproductive system disorders. In women with PCOS, zinc supplementation has a positive effect on many parameters, especially those related to insulin resistance and lipid balance. In primary dysmenorrhea, zinc supplementation before and during each menstrual cycle seems to be an important factor reducing the intensity of menstrual pain. On the other hand, little is known of the role of zinc in endometriosis and in postmenopausal women. Therefore, further studies explaining the potential impact of zinc and its supplementation on female reproductive system would be highly advisable and valuable.

ROLE OF ULTRASOUND IN THE DETECTION OF RECURRENT OVARIAN CANCER

2020 ◽  
Vol 6 (1) ◽  
pp. 23-31
Author(s):  
M. Alisherova ◽  
◽  
M. Ismailova
Keyword(s):  
Ovarian Cancer ◽  
Surgical Treatment ◽  
Reproductive System ◽  
Malignant Tumors ◽  
Recurrent Ovarian Cancer ◽  
Primary Diagnosis ◽  
Female Reproductive System

Currently, there are no standard approaches to monitoring patients with ovarian cancer (OC). While the role of ultrasound (US) has been identified in the primary diagnosis of OS, it is still controversial during the subsequent surgical treatment of OC. In world statistics, ovarian cancer is consistently among the four main localizations of malignant tumors of the female reproductive system, along with tumors of the breast, body and cervix.

scholarly journals Species Comparison of the Role of p38 MAP Kinase in the Female Reproductive System

2009 ◽  
Vol 22 (2) ◽  
pp. 109-124 ◽  
Author(s):  
Zaher A. Radi ◽  
Rosemary A. Marusak ◽  
Dale L. Morris
Keyword(s):  
Map Kinase ◽  
Reproductive System ◽  
P38 Map Kinase ◽  
Female Reproductive System ◽  
Species Comparison

scholarly journals Bitter Taste Receptors Expression in Human Granulosa and Cumulus Cells: New Perspectives in Female Fertility

Cells ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 3127
Author(s):  
Bianca Semplici ◽  
Francesca Paola Luongo ◽  
Sofia Passaponti ◽  
Claudia Landi ◽  
Laura Governini ◽  
...  
Keyword(s):  
Reproductive System ◽  
Bitter Taste ◽  
Receptor Activation ◽  
Female Fertility ◽  
Human Reproduction ◽  
Receptor Subtype ◽  
Taste Receptors ◽  
Female Reproductive System ◽  
Bitter Taste Receptors

Bitter taste receptors (TAS2RS) expression is not restricted to the oral cavity and the presence of these receptors in the male reproductive system and sperm provides insights into their possible role in human reproduction. To elucidate the potential role of TAS2Rs in the female reproductive system, we investigated the expression and localization of bitter taste receptors and the components of signal transduction cascade involved in the pathway of taste receptors in somatic follicular cells obtained from women undergoing assisted reproductive techniques. We found that TAS2R genes are expressed in both cumulus (CCs) and granulosa (GCs) cells, with TAS2R14 being the most highly expressed bitter receptor subtype. Interestingly, a slight increase in the expression of TAS2R14 and TAS2R43 was shown in both GCs and CCs in young women (p < 0.05), while a negative correlation may be established between the number of oocytes collected at the pickup and the expression of TAS2R43. Regarding α-gustducin and α-transducin, two Gα subunits expressed in the taste buds on the tongue, we provide evidence for their expression in CCs and GCs, with α-gustducin showing two additional isoforms in GCs. Finally, we shed light on the possible downstream transduction pathway initiated by taste receptor activation in the female reproductive system. Our study, showing for the first time the expression of taste receptors in the somatic ovarian follicle cells, significantly extends the current knowledge of the biological role of TAS2Rs for human female fertility.

scholarly journals Aromatase P450 activity in the natural menstrual cycle and during controlled ovarian stimulation

2017 ◽  
Vol 66 (5) ◽  
pp. 46-55 ◽  
Author(s):  
Pavel P. Yakovlev
Keyword(s):  
Reproductive System ◽  
Oocyte Quality ◽  
Aromatase Activity ◽  
Female Reproductive System ◽  
Vitro Fertilization ◽  
P450 Enzyme ◽  
Follicular Response ◽  
P450 Activity

The Aim of the study was to assess modern considerations about the role of aromatase P450 enzyme in female reproductive system and the effect of its activity on the protocols of in vitro fertilization (IVF). Materials: foreign and Russian literature data from 1978 to 2016. Methods:review and synthesis of publications has been performed. Conclusions: Ovarian aromatase is the key steroidogenesis enzyme of the female reproductive system. Its activity depends on many factors, both of intraovarian and extragonadal origin. The ovarian follicular response and oocyte quality in IVF may depend on aromatase activity.

scholarly journals The Role of Apelin in the Functioning of the Reproductive System

2019 ◽  
Vol 4 (3) ◽  
pp. 7-17
Author(s):  
A. O. Shpakov ◽  
K. V. Derkach
Keyword(s):  
Reproductive System ◽  
Animal Studies ◽  
Polycystic Ovary ◽  
Signaling Cascades ◽  
Cancer Information ◽  
Target Cells ◽  
Follicular Cells ◽  
Ovary Syndrome ◽  
Wide Range

Adipokine apelin through the apelin receptors activates a wide range of signaling cascades in the target cells and controls their growth, differentiation, apoptosis, and energy metabolism. In the recent years, the evidence has been obtained that all components of the hypothalamic-pituitary-gonad axis, in which apelin and its receptor are expressed, are targets of apelin. In the hypothalamus, apelin modulates the activity of the melanocortin and ghrelin systems and indirectly affects the production of gonadoliberin. In the ovaries, it controls the growth and maturation of the follicles, stimulates the angiogenesis, and affects the basal and stimulated by the other factors steroidogenic activity in follicular cells. The changes in the apelin signaling system are closely associated with dysfunctions of the female reproductive system, such as polycystic ovary syndrome, endometriosis, and cancer. Information on the regulation of the male reproductive system by apelin is limited to animal studies showing the effect of apelin on the hypothalamic components of the gonad axis. The participation of apelin in the regulation of the reproductive system opens up the broad opportunities for the development of new approaches for the correction of abnormalities in this system and for the treatment of infertility.

Non-steroidal anti-inflammatory drugs for the prevention of post-endoscopic retrograde cholangiography pancreatitis Short title: Post-ERCP pancreatitis prevention

2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Mirghani HO
Keyword(s):  
Diclofenac Sodium ◽  
Route Of Administration ◽  
The Body ◽  
Endoscopic Retrograde ◽  
Randomized Controlled Studies ◽  
Conflicting Objectives ◽  
The Usa ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Background: Post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) is a serious disease. The role of nonsteroidal anti-inflammatory drugs (NSAIDs) in the prevention of PEP is conflicting. Objectives: This review aimed to assess the preventive role of NSAIDs in PEP with special emphasis on the dose and route of administration. Methods: We searched PubMed and Google Scholar for relevant observational studies published in English during the period from January 2010 to January 2020. The terms post-ERCP pancreatitis, diclofenac sodium, indomethacin, NSAIDs, dose, route of administration were used. Results: Of the 179 identified, 19 full texts were screened and included in the review. Ten studies were from Europe, seven from Asia and two were published in the USA, the studies showed that NSAIDs were effective in preventing PEP when used rectally or intramuscularly, higher doses are more efficacious and the combination with stents was not superior, careful patients selection is needed in particular regarding the body mass index. Conclusion: NSAIDs were effective in PEP prevention; however, the evidence is weak due to the observational nature and the different methods used in the included studies. Randomized controlled studies are needed to solve the issue.

Memoirs: The Origin and Nature of the Egg Membranes in Chirocephalus Diaphanus

1938 ◽  
Vol s2-80 (320) ◽  
pp. 553-565
Author(s):  
MARY L. MAWSON ◽  
C. M. YONGE
Keyword(s):  
Reproductive System ◽  
Duct Cell ◽  
The Body ◽  
Female Reproductive System ◽  
Inner Membrane ◽  
Especial Reference ◽  
Gland Cells ◽  
Egg Case ◽  
Chirocephalus Diaphanus ◽  
Uterine Glands

1. The anatomy of the female reproductive system in Chirocephalus diaphanus is described with especial reference to the paired anterior and posterior masses of uterine glands. 2. The gland-cells are arranged in pairs surrounded by a common membrane and served by a single duct formed by a separate duct-cell, representing possibly an ingrowth of the uterine epithelium. 3. The glands increase greatly in size during development owing to the formation of a granular secretion which is apparently formed in the nucleus and gradually displaces the original cytoplasm. 4. The egg-case consists of an inner membrane which is chitinous and is formed by the oviducal epithelium, and an outer thicker, rugose membrane which is non-chitinous and is secreted by the uterine glands. 5. Attention is drawn to the close resemblance to conditions in the Decapoda. The inner membrane in both cases is chitinous and formed in the oviduct, while the uterine secretion has much in common with the secretion of the cement glands, but is concerned with protection only and not also with attachment to the body of the female.

The Role of Social Desirability, Negative Affectivity, and Female Reproductive System Symptoms in Differences in Reporting Symptoms by Men and Women

1999 ◽  
Vol 85 (1) ◽  
pp. 54-62 ◽  
Author(s):  
Charles L. Sheridan ◽  
Moira A. Mulhern ◽  
Dawn Martin
Keyword(s):  
Health Status ◽  
Social Desirability ◽  
Reproductive System ◽  
Emotional Health ◽  
Negative Affectivity ◽  
Female Reproductive System ◽  
Men And Women ◽  
Emotional Component ◽  
Almost All

52 women and 38 men completed the Inventory of Health Status, Version 2, a measure of somatic health, and the Cornell Medical Index which provided separate scores for somatic and emotional health. The Personal Style Inventory was given, from which measures of Social Desirability and Negative Affectivity were utilized. Multiple regressions were done separately with scores on the Inventory of Health Status and the Cornell Emotional component, and scores on Social Desirability, Negative Affectivity, and sex as predictors. Scores on Social Desirability and Negative Affectivity were forced into the equation first. For the Inventory of Health Status, sex alone contributed significantly to the final equation. For scores on the Cornell Index's emotional component both sex and scores on negative affectivity had significant beta weights. Analysis of items from the Inventory of Health Status was done to examine the role of symptoms pertaining to women's reproductive system, and almost all the items that differed by sex were either clearly or possibly specific female reproductive items, e.g., “Abnormal menstruation.” Similar analyses were not possible for the organic component of the Cornell Index, which has different items for reproductive systems of men and women. The complexity of the female reproductive system may play a central role in sex differences in symptom reporting and perhaps of emotional distress, but other interpretations are discussed.

Studies on the morphology of Macrolaimus arboreus Truskova & Eroshenko, 1977 (Rhabditida: Chambersiellidae) from Iran

Nematology ◽  
2018 ◽  
Vol 20 (5) ◽  
pp. 441-447 ◽  
Author(s):  
Ebrahim Shokoohi ◽  
Hadi Panahi ◽  
Hendrika Fourie ◽  
Joaquín Abolafia
Keyword(s):  
Body Length ◽  
Excretory Pore ◽  
Reproductive System ◽  
Tail Length ◽  
The Body ◽  
Female Reproductive System ◽  
Female Tail ◽  
Length Measurements

Summary A population of Macrolaimus arboreus was collected from the rhizosphere of pine in Iran. This population of M. arboreus is characterised by the body length, 800-1010 μm in females, lip region with six seta-like papillae directed anteriad, stoma nearly as long as wide (9-11 × 7 μm), with cheilostom slightly longer than gymnostom and cheilorhabdia and gymnorhabdia well-developed, pharyngeal corpus 1.8-2.0 times the isthmus length, with slightly swollen metacorpus, excretory pore located at isthmus level, female reproductive system monodelphic-prodelphic reflexed with short post-vulval uterine sac, female tail conical (57-67 μm, c = 13.7-15.0, c′ = 3.5-3.8), ending in an acute tip which is weakly curved dorsad, and phasmids at 54-60% of tail length. Measurements and illustrations, including SEM, are provided.

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