scholarly journals Associations of Urinary Phytoestrogen Concentrations with Sleep Disorders and Sleep Duration among Adults

Nutrients ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 2103 ◽  
Author(s):  
Jing Sun ◽  
Hong Jiang ◽  
Weijing Wang ◽  
Xue Dong ◽  
Dongfeng Zhang

Current evidence on the relationship of phytoestrogens with sleep is limited and contradictory. In particular, studies on individual phytoestrogens and sleep have not been reported. Thus, this study aimed to appraise the associations of individual phytoestrogens with sleep disorders and sleep duration. This cross-sectional study comprising 4830 adults utilized data from the National Health and Nutrition Examination Survey 2005–2010. Phytoestrogens were tested in urine specimens. Sleep disorders and sleep duration were based on a self-reported doctor’s diagnosis and usual sleep duration. The main analyses utilized logistic and multinomial logistic regression models and a restricted cubic spline. In the fully adjusted model, compared with tertile 1 (lowest), the odds ratios (95% confidence intervals (CIs)) of sleep disorders for the highest tertile of urinary concentrations of enterolactone, enterodiol, and O-desmethylangolensin were 0.64 (0.41–1.00), 1.54 (1.07–2.21), and 1.89 (1.26–2.85), respectively. Linear inverse, approximatively linear positive, and inverted L-shaped concentration–response relationships were found between enterolactone, enterodiol, and O-desmethylangolensin and sleep disorders, respectively. Compared with normal sleep (7–8 h/night), the relative risk ratio (RRR) (95% CI) of very short sleep for enterolactone was 0.56 (0.36–0.86), and the RRR (95% CI) of long sleep risk for genistein was 0.62 (0.39–0.99). Furthermore, negative associations of genistein with sleep disorders and enterolactone with long sleep risk, as well as positive associations of enterodiol with both long and very short sleep, were observed in the stratified analysis by age or gender. Finally, a notable finding was that urinary O-desmethylangolensin concentration was positively related to sleep disorders in both females aged 40–59 years and non-Hispanic Whites but inversely associated with sleep disorders in both females aged 60 years or over and other Hispanics. Our findings suggested that enterolactone and genistein might be beneficial for preventing sleep disorders or non-normal sleep duration among adults, and enterodiol might be adverse toward this goal. However, the association of O-desmethylangolensin with sleep disorders might be discrepant in different races and females of different ages.

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1475
Author(s):  
Jia Luo ◽  
Honghan Ge ◽  
Jing Sun ◽  
Kangyu Hao ◽  
Wenqin Yao ◽  
...  

The relationship between ω-3 and ω-6 fatty acids consumption and sleep disorders or duration are controversial. Therefore, we used the data of the National Health and Nutrition Examination Survey 2007–2016 in this cross-sectional study to explore their relationships. ω-3 and ω-6 fatty acids consumption was assessed using two 24 h dietary recall interviews. Sleep disorders and sleep duration were based on self-reported data. Logistic regression models and restricted cubic spline analyses were used. Compared with tertile one, the odds ratios (ORs) and 95% confidence intervals (CIs) of sleep disorders for the second tertile of ω-6 fatty acid intake and the highest tertile of ω-6:ω-3 ratio were 1.30 (1.04–1.62) and 1.36 (1.08–1.70), respectively. Inverse U-shaped and linear dose–response relationships were observed between dietary ω-6 fatty acid intake and ω-6:ω-3 ratio and sleep disorders, respectively. In addition, ω-3 fatty acid consumption was adversely related to sleep disorders in men and the OR (95% CI) was 0.68 (0.49–0.95). Compared with normal sleep duration, ω-3 fatty acid consumption was negatively related to very short, short, and long sleep duration risk. The relative risk ratios (RRRs) were 0.53 (0.35–0.81), 0.79 (0.67–0.93), and 0.81 (068–0.98), respectively. The RRR of very short sleep for ω-6 fatty acid consumption was 0.57 (0.45–0.73). Our study indicates that ω-6 fatty acid consumption and the ω-6:ω-3 ratio are positively associated with the risk of sleep disorders, while the negative association between ω-3 fatty acids and sleep disorders may exist only in men. Furthermore, ω-3 and ω-6 fatty acid consumption are negatively related to the risk of non-normal sleep duration.


SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A322-A323
Author(s):  
N P Bowles ◽  
S A Shea

Abstract Introduction Cannabis use is on the rise in the US, and while the cannabis plant and related compounds are considered to have low toxicity, the impact on physiology including sleep remains unclear. Further, the bulk of cannabis research has focused on adolescents and young adults despite growing use among the elderly. Thus, this analysis sought to determine the impact of the frequency of cannabis use on sleep duration and determine if this relationship varies by age. Methods This cross-sectional study used data from the 2016-2018 Behavioral Risk Factor Surveillance System surveys. Multinomial logistic regression was used to evaluate the association between the frequency of cannabis use, 0-30 times over the prior 30 days; and average sleep duration, short (<7 hours); recommended (7-9 hours); and long (>9 hours) sleep. Results The study sample included 235,667 participants (48% male, 43% 18-44 years old and 35% 44-64 years old) of which 14,122 consumed cannabis. The weighted proportion who reported using cannabis 1-4x, 5-15x, or more than 16x/month were 3.1% (95% CI, 3.0%-3.3%), 2.1% (2.0%-2.2%), and 4.4% (4.2%-4.6%) respectively. In an age stratified model adjusted for sociodemographic and clinical characteristics, there were no associations between sleep and cannabis use up to 15x/month. Among those adults who consumed cannabis more than 16x/month: (1) 18-44 year olds were more likely to report either short sleep (risk ratio (RR), 1.21; 95% CI, 1.05-1.39) or long sleep (RR, 1.57; 95% CI, 1.11-2.22) as opposed to the recommended amount of sleep; whereas (2) 44-64 year olds demonstrated an increased risk for long sleep (RR, 1.77; 95% CI, 1.09-2.89); and (3) participants 65 years and older demonstrated an increased risk for short sleep (RR, 1.61; 95% CI, 1.04-2.49). Conclusion We demonstrate that modest cannabis use was not associated with sleep, whereas daily cannabis use is associated with age-dependent sleep duration above and below the recommended amount. Support KL2TR002370, 2R25HL105444-09.


Author(s):  
Lovro Štefan ◽  
Goran Vrgoč ◽  
Tomislav Rupčić ◽  
Goran Sporiš ◽  
Damir Sekulić

The main purpose of the study was to explore the associations of sleep duration and sleep quality with physical activity (PA). In this cross-sectional study, participants were 894 elderly individuals (mean age 80 ± 3 years; 56.0% women) living in nursing homes. PA, sleep duration, and sleep quality (based on the Pittsburgh Sleep Quality Index (PSQI)) were self-reported. The associations of sleep duration and sleep quality with PA at the nursing home level were analyzed using generalized estimating equations with clustering. Participants reporting short sleep duration (<6 h; OR = 0.45; 95% CI 0.25–0.80) were less likely to report sufficient PA, yet those reporting long sleep duration (>9 h; OR = 2.61; 95% CI 1.35–5.02) and good sleep quality (<5 points; OR = 1.59; 95% CI 1.19–2.12) were more likely to report sufficient PA. When sleep duration and sleep quality were entered into the same model, the same associations remained. This study shows that elderly individuals who report short sleep duration are less likely to meet PA guidelines, while those who report long sleep duration and good sleep quality are more likely to meet PA guidelines. Strategies aiming to improve sleep duration and sleep quality are warranted.


2017 ◽  
Vol 45 (3) ◽  
pp. 984-992 ◽  
Author(s):  
Jiang Mohan ◽  
Guo Xiaofan ◽  
Sun Yingxian

Objective To investigate the current situation of sleep status and examine its association with depression among counties in rural areas of Liaoning Province, China. Methods This cross-sectional study was conducted from January 2012 to August 2013 in Northeast China. A total of 11,276 subjects aged ≥35 years were surveyed and completed the Patient Health Questionnaire-9; each participant answered questions about their sleep duration. Results For individuals with a sleep time of ≤6, 6–7, 7–8, 8–9, and ≥9 h, the respective risk of depression was 10.8%, 3.7%, 2.6%, 2.7%, and 5.7% in subjects younger than 65 years old and 15.2%, 5.4%, 3.2%, 6.5%, and 8.6% in those 65 years old or older. Conclusion In the rural population of Liaoning Province, sleep duration and depression are closely related. Both short sleep and long sleep are risk factors for depression. Optimizing sleep status may contribute to good physical and mental health.


2019 ◽  
Vol 8 (10) ◽  
pp. 3334
Author(s):  
AbdulazizA Alrashed ◽  
KholoudA Althakafi ◽  
KhalidI Aljammaz ◽  
IhdaaJ Abdulwahab ◽  
Raghad Hamza ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Juan Luis Romero Cabrera ◽  
Mercedes Sotos-Prieto ◽  
Antonio García Ríos ◽  
Steven Moffatt ◽  
Costas A. Christophi ◽  
...  

IntroductionCardiovascular disease is the leading cause of on-duty fatalities among U.S. firefighters. Research has demonstrated that many modifiable risk factors are contributors to the high prevalence of cardiometabolic risk factors. The current study aimed to assess whether sleep is associated with cardiometabolic risk factors among Indianapolis firefighters. The findings could support improving sleep hygiene in this population.Material and MethodsThis cross-sectional study was conducted from the baseline data of eligible firefighters enrolled in “Feeding America’s Bravest”, a Mediterranean diet lifestyle intervention within the Indiana Fire Departments. Participants’ sleep quality was categorized as “good” (≤ 8 points) or “bad” (&gt;8 points) by a sleep quality questionnaire based on some questions from Pittsburgh Sleep Quality Index. In addition, firefighters’ sleep duration was stratified based on the number of hours slept per night (≤6 as “short sleep” or &gt;6 hours as normal). Linear and logistic regression models were used to examine the association of sleep with cardiometabolic risk factors.ResultsA total of 258 firefighters were included. Bad sleepers had higher weight, greater waist circumference, higher body mass index (BMI), and increased body fat (all p&lt;0.01) compared to good sleepers. Similarly, participants with short sleep duration were heavier (p&lt;0.02), had greater BMI (p&lt;0.02) and increased body fat (p&lt;0.04) compared with participants with normal sleep duration. Both bad and short sleepers had a higher prevalence of hypertension and obesity (p &lt;0.05).ConclusionsOur study supports that both sleep quality and quantity are associated with cardiometabolic risk among firefighters.


2013 ◽  
Author(s):  
Rodrigo M. Carrillo-Larco ◽  
Antonio Bernabé-Ortiz ◽  
J. Jaime Miranda ◽  
Jorge Rey de Castro

Sleep duration, either short or long, has been associated with diseases such as obesity, type-2 diabetes and cardiovascular diseases. Characterizing the prevalence and patterns of sleep duration at the population-level, especially in resource-constrained settings, will provide informative evidence on a potentially modifiable risk factor. The aim of this study was to explore the patterns of sleep duration in the Peruvian adult and adolescent population, together with its socio-demographic profile. This is a cross-sectional study, secondary analysis of the Use of Time National Survey conducted in 2010. Weighted means and proportions were used to describe sleep duration according to socio-demographic variables. Poisson regressions, taking into account the multistage sampling design of the survey, were used to calculate crude and adjusted prevalence ratios (PR) and 95% confidence intervals (95% CI). Main outcomes were short- (<6 hours) and long-sleep duration (≥9 hours). A total of 12,424 observations, mean age 35.8 years (SD ±17.7), 50.6% males, were included in the analysis. On average, Peruvians slept 7.7 hours (95% CI 7.4-8.0) on weekdays and 8.0 hours (95% CI 7.8-8.1) during weekends. The proportions of short- and long-sleep, during weekdays, were 4.3% (95% CI 2.9%-6.3%) and 22.4% (95% CI 14.9%-32.1%), respectively. Regarding urban and rural areas, a much higher proportion of short-sleep was observed in the former. On the multivariable analysis, compared to regular-sleepers (≥6 to <9 hours), short-sleepers were twice more likely to be older and to have higher educational status, and 50% more likely to be currently employed. Similarly, relative to regular-sleep, long-sleepers were more likely to have a lower socioeconomic status as per educational attainment. In this nationally representative sample, the sociodemographic profile of short-sleep contrasts the long-sleep. These scenarios in Peru, as depicted by sleeping duration, differ from patterns reported in other high-income settings and could serve as the basis to inform and to improve sleep habits in the population.


2014 ◽  
Vol 1 (2) ◽  
Author(s):  
Mey Relda Angels

Abstract: Obesity is defined as an abnormal accumulation of body fat in proportion to body size. Obesity is a public health crisis that is very substantial. The prevalence of obesity is increasing rapidly in many industrialized countries around the world and become a pandemic that needs immediate attention. Cause of obesity is more complex than the simple paradigm of energy imbalance, but various mechanisms contribute to obesity, including short sleep duration. The purpose of this study was to describe sleep duration and overweight adolescents and to determine the relationship of sleep duration and overweight. This research is an analytic survey with cross sectional study. Study was conducted in junior and senior high school Pax Christi and Rex Mundi Manado, obtained 32 samples of survey respondents with a body mass index above 23.0. Characteristics of the respondents, namely: Age between 14-16 years ever with 15 people (46.9%); Body mass index between 23 to 29.9 were 19 respondents (59.3%); Age at the start of fat, between the ages of 11-15 years as many as 20 people (62.5%); Data diet, greasy 15 respondents (46.9%); Data bedtime, sleep 5-7 hours a night, 21 respondents (65.6%), length of time between the 30 minute nap - 1 hour and between 1 – 2 hours have 13 respondents (40.6%) each. Based on the results of the study, short sleep pattern at night is associated with obesity among (teenage students) of the respondents. Increase and decrease grehlin / leptin, plays a role in relation to the increase in sleep patterns diets ultimately cause obesity. Keywords: Obesity, short sleep patterns, grehlin, leptin, increased appetite.Abstrak: Obesitas didefinisikan sebagai akumulasi abnormal dari lemak tubuh dibandingkan dengan ukuran tubuh normal. Obesitas merupakan krisis kesehatan masyarakat yang sangat substansial. Prevalensi obesitas meningkat dengan cepat di sejumlah negara industri di seluruh dunia dan menjadi pandemik yang memerlukan perhatian segera. Penyebab obesitas lebih kompleks daripada paradigma sederhana ketidakseimbangan energi, namun berbagai mekanisme turut berperan didalamnya, termasuk durasi tidur yang singkat. Tujuan penelitian ini adalah untuk mengetahui gambaran durasi tidur pada remaja dengan kelebihan berat badan dan untuk mengetahui hubungan durasi tidur pada remaja dengan kelebihan berat badan. Penelitian ini bersifat survey analitik dengan study cross sectional. Penelitian dilakukan di SMP Pax Christi dan SMA Rex Mundi Manado, diperoleh 32 sampel responden penelitian dengan indeks massa tubuh diatas 23,0. Karakteristik responden yaitu: Umur terbanyak antara 14-16 tahun yaitu 15 orang (46,9 %); Indeks massa tubuh antara 23-29,9 sebanyak 19 responden (59,3 %); Umur saat mulai gemuk, antara umur 11-15 tahun yaitu sebanyak 20 orang (62,5 %); Data pola makan, makanan berminyak 15 responden (46,9 %); Data waktu tidur, tidur malam 5-7 jam, 21 responden (65,6 %); Lama waktu tidur siang antara 30 menit-1 jam dan antara 1-2 jam yaitu masing-masing 13 responden (40,6 %). Berdasarkan hasil penelitian kesimpulannya, pola tidur yang singkat pada malam hari berhubungan dengan peningkatan berat badan dari responden.Peningkatan grehlin dan penurunan leptin, memegang peranan dalam hubungan pola tidur dengan peningkatan pola makan yang pada akhirnya menyebabkan kegemukan.Kata kunci: Obesitas, pola tidur singkat, grehlin, leptin, peningkatan nafsu makan.


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