scholarly journals Nicotinamide Riboside—The Current State of Research and Therapeutic Uses

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1616 ◽  
Author(s):  
Mario Mehmel ◽  
Nina Jovanović ◽  
Urs Spitz
Keyword(s):  
Health Benefits ◽  
Modern Society ◽  
Nutritional Supplement ◽  
The Body ◽  
Potential Health ◽  
Nicotinamide Riboside ◽  
Current State ◽  
Therapeutic Uses ◽  
State Of Research ◽  
Published Research

Nicotinamide riboside (NR) has recently become one of the most studied nicotinamide adenine dinucleotide (NAD+) precursors, due to its numerous potential health benefits mediated via elevated NAD+ content in the body. NAD+ is an essential coenzyme that plays important roles in various metabolic pathways and increasing its overall content has been confirmed as a valuable strategy for treating a wide variety of pathophysiological conditions. Accumulating evidence on NRs’ health benefits has validated its efficiency across numerous animal and human studies for the treatment of a number of cardiovascular, neurodegenerative, and metabolic disorders. As the prevalence and morbidity of these conditions increases in modern society, the great necessity has arisen for a rapid translation of NR to therapeutic use and further establishment of its availability as a nutritional supplement. Here, we summarize currently available data on NR effects on metabolism, and several neurodegenerative and cardiovascular disorders, through to its application as a treatment for specific pathophysiological conditions. In addition, we have reviewed newly published research on the application of NR as a potential therapy against infections with several pathogens, including SARS-CoV-2. Additionally, to support rapid NR translation to therapeutics, the challenges related to its bioavailability and safety are addressed, together with the advantages of NR to other NAD+ precursors.

scholarly journals Nutraceutical potentials of synergic foods: a systematic review

2019 ◽  
Vol 6 (1) ◽  
Author(s):  
Tharani Devi Natarajan ◽  
Janci Rani Ramasamy ◽  
Kirthika Palanisamy
Keyword(s):  
Chronic Diseases ◽  
Health Benefits ◽  
Nutrient Deficiency ◽  
Value Added ◽  
Well Being ◽  
Active Role ◽  
The Body ◽  
Health Food ◽  
Potential Health ◽  
Nutrition Research

AbstractFood synergy is a concept of linking foods to health. Food consists of mixtures of nutrients, serving as a fuel for the body. When synergistic foods are put together, the evidence for potential health benefits becomes stronger than individual foods. Nutrient deficiency is a known phenomenon in many individuals, and synergy plays a very important role in combating the nutritional deficiency. Today’s consumer expresses high interest to build knowledge on the active role of food in their well-being, as well as in the prevention of non-transmissible chronic diseases. Functional foods and their active compounds play a vital role in preventing chronic diseases, improving immunity, and decreasing infections. The concept of synergy is an overthinking in nutrition research which can enhance effective dietary planning value added to the forthcoming nutrition research. This paper gives an overview of various synergic combinations of food components and their interactions within the food and with the human system to attain ideal health benefits.

Wearable Power Assist Robot Driven with Pneumatic Rubber Artificial Muscles

2016 ◽  
pp. 235-250 ◽  
Author(s):  
Toshiro Noritsugu
Keyword(s):  
Research And Development ◽  
Nursing Care ◽  
Soft Power ◽  
Social Needs ◽  
The Body ◽  
Care Work ◽  
Lower Limbs ◽  
Artificial Muscles ◽  
Current State ◽  
State Of Research

Recently, the attention has been focused on developing a wearable power assist robot by installing an actuator, such as motors, in the body and assisting and enhancing muscular power; there has been a considerable increase in research and development in some institutes and companies worldwide. Various types of wearable power assist robots have been proposed to support the upper and lower limbs, waist, and so on, which are to be used for the operational support of elderly and disabled people, nursing care work, and heavy lifting work in production sites. Some of them have been commercialized and their promotions have been advanced. Their social needs are extremely high, and there is an expectation of further improvements of assisting effect, installation performance, safety and convenience and affordability. In this paper, after the current state of research and development of this kind of robot is outlined, and our researches on pneumatic rubber artificial muscles, exoskeleton type standing motion assist devices, and wearable, lightweight, and soft power assist robots without an exoskeleton are introduced.

scholarly journals The Dharmaputrikā Saṃhitā: Preliminary Notes on an Early Text on Yoga

2020 ◽  
Vol 3 ◽  
pp. 5-76
Author(s):  
Christèle Barois ◽  
Keyword(s):  
The Body ◽  
Empirical Knowledge ◽  
Yoga Practice ◽  
Ancient Text ◽  
Current State ◽  
History Of ◽  
Early Text ◽  
State Of Research ◽  
High Level ◽  
Indian Medicine

This essay aims to present the current state of research on the Dharmaputrikā Saṃhitā, an ancient text on yoga which describes, with an exceptional depth of detail and a high level of bodily technicality, internal yogic practices. The study of the Dharmaputrikā Saṃhitā was initiated as part of the ERC-funded AyurYog project, which was led by Dagmar Wujastyk (2015–2020), whose central aim was to examine the link between yoga and classical Indian medicine, two distinct fields of knowledge in the Sanskrit tradition. Not only does chapter Ten (called yogacikitsā) of the Dharmaputrikā Saṃhitā describe “therapy in the context of yoga practice,” but it also appears to integrate within its discourse the practice’s physical and mental effects on the body at each stage of the yoga process, thus reflecting an empirical knowledge of physiology. This essay introduces the dating, authorship, textual history, and reception of the text. It provides preliminary research on parallel passages in other works, and proposes that the Dharmaputrikā Saṃhitā is a textual testimony of ancient yoga practices referred to as the “yoga of Hiraṇyagarbha.” On the basis of the critical edition, which is yet to be published, it offers the reader an annotated and detailed summary of the work’s content, along with various discussions of important questions raised by broader considerations on the history of ancient yoga.

scholarly journals Antinutrients in Plant-based Foods: A Review

2019 ◽  
Vol 13 (1) ◽  
pp. 68-76 ◽  
Author(s):  
Aneta Popova ◽  
Dasha Mihaylova
Keyword(s):  
Human Health ◽  
Healthy Lifestyle ◽  
Modern Society ◽  
Negative Influence ◽  
The Body ◽  
Nutritional Deficiencies ◽  
Easy Access ◽  
Positive Effects ◽  
Food Content ◽  
Published Research

Modern society has easy access to a vast informational database. The pursuit of sustainable green and healthy lifestyle leads to a series of food choices. Therefore, it is of importance to provide reliable, comprehensive and up-to-date information about food content including both nutritional and antinutritional elements. Nutrients are associated with positive effects on human health. Antinutrients, on the other hand, are far less popular for the contemporary man. They are highly bioactive, capable of deleterious effects as well as some beneficial health effects in man, and vastly available in plant-based foods. These compounds are of natural or synthetic origin, interfere with the absorption of nutrients, and can be responsible for some mischievous effects related to the nutrient absorption. Some of the common symptoms exhibited by a large amount of antinutrients in the body can be nausea, bloating, headaches, rashes, nutritional deficiencies, etc. Phytates, oxalates, and lectins are few of the well-known antinutrients. Science has acknowledged several ways in order to alter the negative influence antinutrients exhibiting on human health. Mechanical, thermal and biochemical approaches act synergistically to provide food with lower antinutritional levels. The purpose of this review was to synthesize the availability of antinutrients, clear their effect on the human body, and commemorate possible paths to disable them. This review provides links to the available literature as well as enables a systematic view of the recently published research on the topic of plant-based antinutrients.

scholarly journals Bioactive components of two species of locally grown nuts: Their potential health benefits and implications for healthy living

2021 ◽  
Vol 4 (12) ◽  
pp. 301
Author(s):  
Ayomadewa Mercy Olatunya
Keyword(s):  
Phenolic Compounds ◽  
Bioactive Compounds ◽  
Research Work ◽  
Health Benefits ◽  
The Body ◽  
Bioactive Components ◽  
Potential Health ◽  
High Burden ◽  
Cashew Nut ◽  
Locally Grown

Background: Bioactive compounds are naturally occurring compounds in plants and animal products. They are known to have a variety of physiological functions in the body system such as: promoting general body development and prevention of the occurrence of some deadly diseases. The high burden of treatment of some deadly diseases like cancer, high blood pressure, and cardiovascular diseases has raised the need for scientists to generate empirical evidence on preventing these diseases using a dietary approach. Nuts have been identified as plants with potential to improve human health and prevent diseases when consumed adequately because of their rich constituents. This research work was conducted to evaluate and elucidate the bioactive components of locally grown nuts and their potential health benefits. Methods: The Phenolic compounds, phytosterols, tocopherols, and tocotrienols contents of the nuts were analyzed using standard methods.  Results: Fourteen phenolic compounds were detected in the two nuts with cinnamic and gallic acids detected in appreciable amounts in groundnuts and caffeic acid in cashew nut. The total amount of tocopherols in cashew nut was 14.08 mg/100g and 37.95 mg/100g in groundnut and the total tocotrienol was 0.85 and 4.00 × 10-3 mg/100g for cashew nut and groundnut respectively. Both samples have high quantity of sistosterol (251.36mg/100g and 238.95 mg/ 100g for cashew nut and groundnut respectively) with cashew nut having significantly higher amount. Conclusion: The results showed that the nuts are rich in bioactive compounds and could be considered as natural sources of bioactive compounds that can be obtained from diets rich in these nuts to prevent the occurrence of certain deadly human diseases that are of high burden worldwide.      Keywords: Phenolic Compounds, Tocopherols, Groundnuts, Cashew nuts

scholarly journals Infectious hepatitis in dogs (state of the problem)

2019 ◽  
pp. 16-21
Author(s):  
G. Zon ◽  
L. Ivanovska ◽  
I. Zon
Keyword(s):  
Clinical Signs ◽  
Infectious Hepatitis ◽  
Study Data ◽  
The Body ◽  
Regional Lymph Nodes ◽  
Current State ◽  
Myocardial Dystrophy ◽  
Multiple Blood ◽  
State Of Research ◽  
Test Use

The paper contains data regarding current state of research and author opinion on realization of diagnostics and therapy improvement in case of infectious hepatitis in dogs based on the form of the disease. A study of worldwide practice and a summary of personal experience of the aspects of clinical manifestation, diagnostics and treatment methods for canine hepatitis have been performed. According to our research canine infectious hepatitis in Sumy region is usually found in dogs at 1-3 (44%) years of age, less of ten at 5-8 (28%) years. The quantity of cases at 3-8 y.o. is 17% and in animals younger than  1 year – 11%. After being introduced into the body, the virus replicates in the regional lymph nodes then appears in the blood (viremia), after 2-3 days it forms masses of core inclusions (Rubart’s bodies) – big, round, acidophilic masses in capillary and vein endothelium in all the organs, especially liver and spleen. As a result liver dystrophy occurs and general body intoxication follows. Further development of the process results in renal and myocardial dystrophy,appearance of multiple blood effusions on mucous and serous membranes. After the neural centers of the brain and spine are being affected the locomotion disorders are observed.At the stage of acute clinical signs the virus is present in blood and all the exudates, while being observed only in kidneys and urine later. The incubation period of spontaneous hepatitis lasts about 6 to 9 days. Currently there are some cases of an acute and peracute course but chronic and latent courses are prevalent. The organ lesions depend on the severity and course of the disease. Infectious hepatitis is being diagnosed based on epizootological, clinical, pathological and laboratory study data as well as virological research and biological test. Use of a treatment regimen including polyvalent serum, anfluron, cobactan, difeniramine, metoclopramide, furosemide, hepavikel, and crystalline IV solutions allowed shorteningofthe treatment period in comparison to average.

scholarly journals Moringa oleifera is a Prominent Source of Nutrients with Potential Health Benefits

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Zahidul Islam ◽  
S. M. Rashadul Islam ◽  
Faruk Hossen ◽  
Kazi Mahtab-ul-Islam ◽  
Md. Rakibul Hasan ◽  
...  
Keyword(s):  
Natural Products ◽  
Moringa Oleifera ◽  
Health Benefits ◽  
The Body ◽  
Plant Origin ◽  
Normal Functioning ◽  
Potential Health ◽  
Therapeutic Properties ◽  
Macro And Micronutrients ◽  
Almost All

Nowadays, the socioeconomic status has been changed a lot, so people are now more concerned about their life style and health. They have knowledge about the detrimental effects of synthetic products. That is why they are interested in natural products. Utilization of natural products of plant origin having fewer side effects has gained popularity over the years. There is immense scope for natural products that can intimate health benefits beyond traditional nutrients. Moringa oleifera is one such tree having tremendous nutritional and medicinal benefits. It is rich in macro- and micronutrients and other bioactive compounds which are important for normal functioning of the body and prevention of certain diseases. Leaves, flowers, seeds, and almost all parts of this tree are edible and have immense therapeutic properties including antidiabetic, anticancer, antiulcer, antimicrobial, and antioxidant. Most of the recent studies suggested that Moringa should be used as a functional ingredient in food. The aim of this review is to focus the use of Moringa oleifera as a potential ingredient in food products.

Music and Emotion: Themes and Development

2011 ◽  
Vol 15 (2) ◽  
pp. 139-145
Author(s):  
Alexandra Lamont ◽  
Tuomas Eerola
Keyword(s):  
Special Issue ◽  
International Conference ◽  
Current State ◽  
Scientific Approach ◽  
Psychology Of Music ◽  
State Of Research ◽  
Published Research ◽  
Music And Emotion ◽  
Selection Of

This special issue draws on a selection of papers presented at the inaugural International Conference on Music and Emotion in Durham in 2009, focusing on the scientific approach to understanding music and emotions. In this editorial we consider the current state of research into music and emotion, drawing comparisons with the earlier special issue of this journal published ten years ago and between the two edited collections which mark progress in this period. We consider issues of theory and methodology in relation to the wider field of psychology of music as illustrated by the papers in this volume and other recently published research, considering some of the barriers towards progress and some of the areas where new insights have been gained.

scholarly journals Therapeutic Perspectives on Chia Seed and Its Oil: A Review

Planta Medica ◽  
2018 ◽  
Vol 84 (09/10) ◽  
pp. 606-612 ◽  
Author(s):  
John Parker ◽  
Amanda Schellenberger ◽  
Amy Roe ◽  
Hellen Oketch-Rabah ◽  
Angela Calderón
Keyword(s):  
Linolenic Acid ◽  
Large Scale ◽  
Health Benefits ◽  
The Body ◽  
Distance Runners ◽  
Potential Health ◽  
Novel Foods ◽  
Related Risk ◽  
Chia Seed ◽  
Overweight Adults

AbstractThe attraction of novel foods proceeds alongside epidemic cardiovascular disease, diabetes, obesity, and related risk factors. Dieticians have identified chia (Salvia hispanica) as a product with a catalog of potential health benefits relating to these detriments. Chia is currently consumed not only as seeds, but also as oil, which brings about similar effects. Chia seeds and chia seed oil are used mainly as a food commodity and the oil is also used popularly as a dietary ingredient used in various dietary supplements available in the U. S. market. Chia seed is rich in α-linolenic acid, the biological precursor to eicosapentaenoic acid, a polyunsaturated fatty acid, and docosahexaenoic acid. Because the body cannot synthesize α-linolenic acid, chia has a newfound and instrumental role in diet. However, the inconclusive nature of the scientific communityʼs understanding of its safety warrants further research and appropriate testing. The focus of this work is to summarize dietary health benefits of S. hispanica seed and oil to acknowledge concerns of adverse events from its ingestion, to assess current research in the field, and to highlight the importance of quality compendial standards to support safe use. To achieve this end, a large-scale literature search was partaken on the two well-known databases, PubMed and SciFinder. Hundreds of articles detailing such benefits as decreased blood glucose, decreased waist circumference and weight in overweight adults, and improvements in pruritic skin and endurance in distance runners have been recorded. These benefits must be considered within the appropriate circumstances.

scholarly journals Myocardial Regeneration via Progenitor Cell-Derived Exosomes

2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Janita A. Maring ◽  
Christien M. Beez ◽  
Volkmar Falk ◽  
Martina Seifert ◽  
Christof Stamm
Keyword(s):  
Clinical Application ◽  
Heart Diseases ◽  
Point Of Care ◽  
The Body ◽  
Experimental Therapy ◽  
Delivery Mode ◽  
Significant Heterogeneity ◽  
Mediated Effects ◽  
Current State ◽  
State Of Research

In the past 20 years, a variety of cell products has been evaluated in terms of their capacity to treat patients with acute myocardial infarction and chronic heart failure. Despite initial enthusiasm, therapeutic efficacy has overall been disappointing, and clinical application is costly and complex. Recently, a subset of small extracellular vesicles (EVs), commonly referred to as “exosomes,” was shown to confer cardioprotective and regenerative signals at a magnitude similar to that of their donor cells. The conceptual advantage is that they may be produced in industrial quantities and stored at the point-of-care for off-the-shelf application, ideally without eliciting a relevant recipient immune response or other adverse effects associated with viable cells. The body of evidence on beneficial exosome-mediated effects in animal models of heart diseases is rapidly growing. However, there is significant heterogeneity in terms of exosome source cells, isolation process, therapeutic dosage, and delivery mode. This review summarizes the current state of research on exosomes as experimental therapy of heart diseases and seeks to identify roadblocks that need to be overcome prior to clinical application.

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