scholarly journals Role of the Proportional Intake of Fortified Mother’s Own Milk in the Weight Gain Pattern of Their Very-Preterm-Born Infants

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1571
Author(s):  
Anna Petrova ◽  
Shannon Eccles ◽  
Rajeev Mehta
Keyword(s):  
Weight Gain ◽  
Preterm Infants ◽  
Average Weight ◽  
Very Preterm ◽  
Feeding Parameters ◽  
Immunological Factors ◽  
Preterm Born ◽  
Mother’S Own Milk ◽  
Challenging Question

Breastfeeding has been recommended for preterm infants as the optimal diet from nutritional, gastrointestinal, immunological, and developmental perspectives. However, the relevance of differing intakes of fortified mother’s own milk (MOM) on the growth of their preterm infants is a challenging question because of the potential risk of extrauterine growth impairment, apart from its essential role in the provision of biological and immunological factors, and the reduction of serious morbidities. We aimed to identify the weight gain pattern in very-preterm-born infants with respect to their proportional intake of fortified MOM. The daily and average weight gain, dietary volume, calories, and proportional intake of fortified MOM were studied in a cohort of 84 very-preterm-born infants during the first 2 weeks post initiation of full enteral feeds. Groups 1, 2, and 3 were comprised of infants with a proportional fortified MOM intake of 85% or more, 35% to 84.9%, and 0 to 34.9%, respectively. Data analysis included regression models and a group-based comparison of the number of infants with weight gain that would be considered minimally acceptable for normal intrauterine growth. The infants’ weight gain was not found to be associated with the proportional intake of fortified MOM or other feeding parameters. Overall, the intergroup variability in the proportion of infants with weight gain less than the lower limit of normal fetal growth was insignificant. During the first 2 weeks post initiation of full enteral feeds, the weight gain pattern of the studied very-preterm-born infants was not significantly dependent on the proportional intake of fortified maternal milk.

scholarly journals Role of probiotics in preterm infants: a randomized controlled trial

2017 ◽  
Vol 4 (2) ◽  
pp. 447 ◽  
Author(s):  
Sukanyaa S. ◽  
Vinoth S. ◽  
Ramesh S.
Keyword(s):  
Weight Gain ◽  
Preterm Infants ◽  
Controlled Trial ◽  
Health Benefit ◽  
Control Group ◽  
P Value ◽  
Average Weight ◽  
Preterm Babies ◽  
Average Weight Gain

Background: Probiotics are live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. Probiotics are proposed to aid in the quicker colonisation of the preterm gut by various mechanisms thereby providing innumerable health benefits to the preterm infants. Hence we conducted a study to analyse the role of probiotics in preterm babies. Our primary aim was to compare the weight gain pattern among preterm infants: those receiving probiotic and those who did not receive the probiotic.Methods: Preterm/VLBW babies were selected, randomized and placed into two groups. One group was given the chosen probiotic and the other was kept as control. The weight gain pattern and the duration of hospital stay among the two groups was compared at the end of one month of age.Results: The average weight gain in the probiotic group was higher than the control group which was statistically significant. (mean difference: 0.230 + 0.11 95% CI: -0.796 to -0.251 p value <0.000).Conclusions: Our study was yet another evidence proving the utility of probiotics in the field of neonatalogy.

Managing mother’s own milk for very preterm infants in neonatal units in 11 European countries

2020 ◽  
Vol 110 (1) ◽  
pp. 123-126
Author(s):  
Carina Rodrigues ◽  
Jennifer Zeitlin ◽  
Emilija Wilson ◽  
Liis Toome ◽  
Marina Cuttini ◽  
...  
Keyword(s):  
Preterm Infants ◽  
European Countries ◽  
Very Preterm Infants ◽  
Very Preterm ◽  
Mother’S Own Milk

scholarly journals Role of beta-2-microglobulin as a biomarker in very preterm and extremely preterm infants with CNS inflammation

PLoS ONE ◽  
2019 ◽  
Vol 14 (5) ◽  
pp. e0216498
Author(s):  
Albert Batista Muñoz ◽  
Stephanie Hadley ◽  
Marti Iriondo Sanz ◽  
Thais Agut Quijano ◽  
Marta Camprubí Camprubí
Keyword(s):  
Preterm Infants ◽  
Cns Inflammation ◽  
Very Preterm ◽  
Extremely Preterm ◽  
Extremely Preterm Infants ◽  
Beta 2 ◽  
Beta 2 Microglobulin

Body Composition in Very Preterm Infants: Role of Neonatal Characteristics and Nutrition in Achieving Growth Similar to Term Infants

Neonatology ◽  
2016 ◽  
Vol 111 (3) ◽  
pp. 214-221 ◽  
Author(s):  
Geneviève Tremblay ◽  
Christine Boudreau ◽  
Sylvie Bélanger ◽  
Odette St-Onge ◽  
Etienne Pronovost ◽  
...  
Keyword(s):  
Body Composition ◽  
Preterm Infants ◽  
Term Infants ◽  
Very Preterm Infants ◽  
Very Preterm

scholarly journals Lack of Effect of L-Carnitine Supplementation on Weight Gain in Very Preterm Infants

2005 ◽  
Vol 25 (7) ◽  
pp. 470-477 ◽  
Author(s):  
Sumati Pande ◽  
Luc P Brion ◽  
Deborah E Campbell ◽  
Yvonne Gayle ◽  
Nora V Esteban-Cruciani
Keyword(s):  
Weight Gain ◽  
Preterm Infants ◽  
Carnitine Supplementation ◽  
Very Preterm Infants ◽  
Very Preterm

Effect Of Early Caffeine Therapy On Weight Gain In Very Preterm Infants

2019 ◽  
Author(s):  
Srinivasan Mani ◽  
Fernanda Kupferman ◽  
Roger Kim
Keyword(s):  
Weight Gain ◽  
Preterm Infants ◽  
Premature Infants ◽  
Repeated Measures ◽  
Analysis Of Covariance ◽  
Very Preterm Infants ◽  
Very Preterm ◽  
Repeated Measures Analysis ◽  
Practical Impact ◽  
Poor Weight Gain

Abstract Background: Premature infants were observed to have poor weight gain for the first 3 weeks after initiating caffeine therapy. The practical impact of this adverse effect in the era of prophylactic (early) caffeine therapy in very preterm infants have not been analyzed well.Methods: A retrospective cohort study was conducted including preterm infants born at < 31 weeks gestation between June 2013 and June 2016. Infants were divided into 2 groups based on the timing of caffeine initiation: less than the 48 hours after birth (early) and 48 or more hours after birth (late). The outcome was weight in grams at the end of 3rd week of life. Independent t-test and repeated-measures analysis of covariance (ANCOVA) were used for analysis. Results: Thirty-nine (84.6%) out of 46 infants born < 31 weeks gestation with a birth weight < 1250 grams were included in the study. Of the 39 infants, 22 received early caffeine therapy and 17 received late caffeine therapy. On comparing the weight at 3 weeks of age between the two groups, the early caffeine group had a significantly better weight gain with a mean weight at 3 weeks being 1140 grams vs 985 grams (p=0.03). Conclusion: In very preterm infants, early caffeine therapy was associated with better weight gain in the first 3 weeks of life.

scholarly journals Importance of Early Postnatal Weight Gain for Normal Retinal Angiogenesis in Very Preterm Infants

2012 ◽  
Vol 130 (8) ◽  
Author(s):  
Carolyn Wu ◽  
Chatarina Löfqvist ◽  
Lois E. H. Smith ◽  
Deborah K. VanderVeen ◽  
Ann Hellström ◽  
...  
Keyword(s):  
Weight Gain ◽  
Preterm Infants ◽  
Very Preterm Infants ◽  
Very Preterm ◽  
Retinal Angiogenesis ◽  
Postnatal Weight Gain

scholarly journals Maturation of Corpus Callosum Anterior Midbody Is Associated with Neonatal Motor Function in Eight Preterm-Born Infants

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Preethi Mathew ◽  
Kerstin Pannek ◽  
Pamela Snow ◽  
M. Giulia D'Acunto ◽  
Andrea Guzzetta ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Preterm Infants ◽  
Motor Function ◽  
Gestational Age ◽  
Diffusion Tensor ◽  
Mean Diffusivity ◽  
Motor Impairments ◽  
Very Preterm Infants ◽  
Very Preterm ◽  
Preterm Born

Background. The etiology of motor impairments in preterm infants is multifactorial and incompletely understood. Whether corpus callosum development is related to impaired motor function is unclear. Potential associations between motor-related measures and diffusion tensor imaging (DTI) of the corpus callosum in preterm infants were explored.Methods. Eight very preterm infants (gestational age of 28–32 weeks) underwent the Hammersmith neonatal neurological examination and DTI assessments at gestational age of 42 weeks. The total Hammersmith score and a motor-specific score (sum of Hammersmith motor subcategories) were calculated. Six corpus callosum regions of interest were defined on the mid-sagittal DTI slice—genu, rostral body, anterior midbody, posterior midbody, isthmus, and splenium. The fractional anisotropy (FA) and mean diffusivity (MD) of these regions were computed, and correlations between these and Hammersmith measures were sought.Results. Anterior midbody FA measures correlated positively with total Hammersmith (rho=0.929,P=0.001) and motor-specific scores (rho=0.857,P=0.007). Total Hammersmith scores also negatively correlated with anterior midbody MD measures (rho=−0.714,P=0.047).Discussion. These results suggest the integrity of corpus callosum axons, particularly anterior midbody axons, is important in mediating neurological functions. Greater callosal maturation was associated with greater motor function. Corpus callosum DTI may prove to be a valuable screening or prognostic marker.

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