Managing mother’s own milk for very preterm infants in neonatal units in 11 European countries

2020 ◽  
Vol 110 (1) ◽  
pp. 123-126
Author(s):  
Carina Rodrigues ◽  
Jennifer Zeitlin ◽  
Emilija Wilson ◽  
Liis Toome ◽  
Marina Cuttini ◽  
...  
Author(s):  
Christina Volder ◽  
Benedicte Juul Work ◽  
Silje Vermedal Hoegh ◽  
Maria-Christina Eckhardt ◽  
Gitte Zachariassen

2014 ◽  
Vol 9 (1) ◽  
pp. 47-48 ◽  
Author(s):  
Mercedes Bonet ◽  
Mélanie Durox ◽  
Béatrice Blondel ◽  
Pascal Boileau ◽  
Véronique Pierrat ◽  
...  

2021 ◽  
Vol 47 (1) ◽  
Author(s):  
Carlo Dani ◽  
Caterina Coviello ◽  
Fiorenza Panin ◽  
Saverio Frosini ◽  
Simonetta Costa ◽  
...  

AbstractObjectiveNon-negligible differences in retinopathy of prematurity (ROP) and its risk factors between different neonatal intensive care units (NICUs) are reported. Our aim was to assess the incidence and risk factors for ROP development in a large cohort of very preterm infants who were assisted in two Italian NICUs.MethodsPreterm infants with gestational age between 23+ 0and 29+ 6weeks were stratified into subgroups of infants who developed ROP and those who did not; their clinical characteristics were compared with univariate and multivariable logistic regression analyses.ResultsWe studied a total of 178 infants of whom 67 (38%) developed ROP (stage 1:n = 12; stage 2:n = 41; stage 3:n = 14). Regression analysis demonstrated that maternal milk (OR 0.979, 95% Cl 0.961–0.998) decreased the risk of developing ROP, while intraventricular hemorrhage (IVH) (OR 2.055, 95% Cl 1.120–3.772) increased it. Moreover, maternal milk was found to decrease (OR 0.981, 95% Cl 0.964–0.997) the risk of ROP at discharge, while RBC transfusion increased it (OR 1.522, 95% Cl 1.208–1.916).ConclusionsIn our cohort the occurrence of ROP was similar to that previously reported. Strategies for promoting the use of mother’s own milk, preventing IVH, and standardizing the approach to RBC transfusions could contribute to decreasing the risk of ROP in very preterm infants.


2017 ◽  
Vol 106 (9) ◽  
pp. 1447-1455 ◽  
Author(s):  
Jennifer Zeitlin ◽  
Anna-Karin Edstedt Bonamy ◽  
Aurelie Piedvache ◽  
Marina Cuttini ◽  
Henrique Barros ◽  
...  

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
C Rodrigues ◽  
J Zeitlin ◽  
E Wilson ◽  
L Toome ◽  
M Cuttini ◽  
...  

Abstract Background There is an ongoing debate about the best practices to handle mother's own milk (MOM) for infants born very preterm (VPT, ≤32 weeks of gestation), specifically to prevent the human cytomegalovirus (HCMV) transmission and bacterial contamination of expressed MOM. Thus, we aimed to compare practices for managing MOM for VPT infants in European neonatal intensive care units (NICUs). Methods Data were collected as part of the EPICE (Effective Perinatal Intensive Care in Europe) study which explored the use of evidence-based practices for the care of VPT infants in 11 European countries. Structured questionnaires were sent to the head of all participating NICUs with at least 10 VPT admissions. Of the eligible 135 NICUs, 134 replied. Results A written protocol for breastfeeding/human milk use was available in 91% of the NICUs. Overall, 34% used human bank milk for all VPT infants whose mothers did not express and 56% reported using fresh MOM without restrictions regarding minimum gestational age, birth weight or risk of HCMV transmission (country range: 0-100%). In 22% of units all VPT infants received MOM pasteurized (country range: 0-73%). HCMV serology on all mothers who express their milk was not required in 71% of units (country range: 7-100%). Among NICUs that performed HCMV serology, 3% provided untreated fresh MOM and 23.5% formula in the case of positive mothers. Systematic bacteriological analyses of MOM were not performed in 76% NICUs (country range: 29-100%) while less than 10% did it for the first milk feeding, 7% every week and 8% with another frequency. Conclusions There are large variations in managing MOM across countries, which could reflect differences in regulations or guidelines, and among the same country NICUs, revealing that different options can operate locally. This variability suggests substantial differences in attitudes about what constitutes best practices among European neonatologists. Key messages We found significant differences across and within European countries for managing MOM for VPT infants suggesting lack of strong recommendations at the international and national level. There is wide variation in what European neonatologists consider best practices. To guide practice and not jeopardise VPT infants from MOM we need strong evidence-based data.


2003 ◽  
Vol 92 (5) ◽  
pp. 1-1 ◽  
Author(s):  
GMSJ Stoelhorst ◽  
SE Martens ◽  
M Rijken ◽  
van Zwieten PHT ◽  
AH Zwinderman ◽  
...  

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