scholarly journals The Effects of Time Restricted Feeding on Overweight, Older Adults: A Pilot Study

Nutrients ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1500 ◽  
Author(s):  
Stephen D. Anton ◽  
Stephanie A. Lee ◽  
William T. Donahoo ◽  
Christian McLaren ◽  
Todd Manini ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Older Adults ◽  
Weight Loss ◽  
Pilot Study ◽  
Adverse Events ◽  
Muscle Mass ◽  
Intermittent Fasting ◽  
Restricted Feeding ◽  
Eating Pattern

A growing body of evidence indicates that time restricted feeding (TRF), a popular form of intermittent fasting, can activate similar biological pathways as caloric restriction, the only intervention consistently found to extend healthy lifespan in a variety of species. Thus, TRF may have the potential to also improve function in older adults. Given the challenges many individuals have in following calorie restriction regimens over long-time periods, evaluation of alternative approaches that may produce weight loss and improve function in overweight, older adults is important. Ten overweight, sedentary older adults (≥65 years) at risk for, or with mobility impairments, defined by slow gait speed (<1.0 m/s) participated in this trial. All participants received the intervention and were instructed to fast for approximately 16 h per day over the entire four-week intervention. Outcomes included changes in body weight, waist circumference, cognitive and physical function, health-related quality of life, and adverse events. Adherence levels were high (mean = 84%) based on days goal was met, and mean weight loss was 2.6 kg (p < 0.01). Since body composition was not measured in this study, it is unclear if the observed weight loss was due to loss of fat mass, muscle mass, or the combination of fat and muscle mass. There were no significant changes in other outcomes; however, there were clinically meaningful changes in walking speed and improvements in quality of life, with few reported adverse events. The findings of this pilot study suggest that time restricted feeding is an acceptable and feasible eating pattern for overweight, sedentary older adults to follow.

scholarly journals Determinants of Adherence in Time-Restricted Feeding in Older Adults: Lessons from a Pilot Study

Nutrients ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 874 ◽  
Author(s):  
Stephanie A. Lee ◽  
Caroline Sypniewski ◽  
Benjamin A. Bensadon ◽  
Christian McLaren ◽  
William T. Donahoo ◽  
...  
Keyword(s):  
Older Adults ◽  
Adverse Events ◽  
Pilot Trial ◽  
Target Range ◽  
Intermittent Fasting ◽  
Activity Levels ◽  
Restricted Feeding ◽  
Eating Pattern ◽  
Eating Time ◽  
Baseline Visit

Time-restricted feeding (TRF) is a type of intermittent fasting in which no calories are commonly consumed for approximately 12–18 hours on a daily basis. The health benefits of this eating pattern have been shown in overweight adults, with improvements in cardiometabolic risk factors as well as the preservation of lean mass during weight loss. Although TRF has been well studied in younger and middle-aged adults, few studies have evaluated the effects of TRF in older adults. Thus, the goal of this study was to evaluate older-adult perspectives regarding the real-world advantages, disadvantages, and challenges to adopting a TRF eating pattern among participants aged 65 and over. A four-week single-arm pre- and post-test design was used for this clinical pilot trial TRF intervention study. Participants were instructed to fast for approximately 16 h per day with the daily target range between 14 and 18 h. Participants were provided with the TRF protocol at a baseline visit, along with a pictorial guide that depicted food items and beverages that were allowed and not allowed during fasting windows to reinforce that calorie-containing items were to be avoided. The trial interventionist called each participant weekly to promote adherence, review the protocol, monitor for adverse events, and provide support and guidance for any challenges faced during the intervention. Participants were instructed to complete daily eating time logs by recording the times at which they first consumed calories and when they stopped consuming calories. At the end of the intervention, participants completed an exit interview and a study-specific Diet Satisfaction Survey (Table 1) to assess their satisfaction, feasibility, and overall experience with the study intervention. Of the 10 participants who commenced the study (mean age = 77.1 y; 6 women, 4 men), nine completed the entire protocol. Seven of the ten participants reported easy adjustment to a 16-hour fast and rated the difference from normal eating patterns as minimal. Eight participants reported no decrease in energy during fasting periods, with greater self-reported activity levels in yardwork and light exercise. Adverse events were rare, and included transient headaches, which dissipated with increased water intake, and dizziness in one participant, which subsided with a small snack. The findings of the current trial suggest that TRF is an eating approach that is well tolerated by most older adults. Six participants, however, did not fully understand the requirements of the fasting regimen, despite being provided with specific instructions and a pictorial guide at a baseline visit. This suggests that more instruction and/or participant contact is needed in the early stages of a TRF intervention to promote adherence.

scholarly journals Association of Physical Activity, Muscle Mass, Strength, and Function to Quality of Life in Older Adults

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 185-186
Author(s):  
Murad Taani ◽  
Chi Cho ◽  
Julie Ellis
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Older Adults ◽  
Muscle Mass ◽  
Handgrip Strength ◽  
Community Dwelling ◽  
Steps Per Day ◽  
Mental Hrqol ◽  
And Function

Abstract Physical inactivity and loss of muscle mass, strength, and function are associated with negative outcomes including disability and a decline in health-related quality of life (HRQoL) among older adults. Older adults living in continuing care retirement communities (CCRCs) are at greater risk for declining physical activity and muscle outcomes compared to community-dwelling older adults. Few researchers studying the association of muscle and physical activity have examined the distinction between physical and mental HRQoL. Understanding the differential association of physical and mental HRQoL to physical activity and muscle outcomes can inform the development of useful interventions. The aim of this study was to examine the relationships between physical activity, muscle mass, strength, function and physical and mental HRQoL. Using a descriptive, correlational design, 105 older adults living in CCRCs were recruited. Light physical activity (LPA), moderate physical activity (MPA), sedentary behavior, and steps per day were assessed using ActiGraph GT3X. Appendicular skeletal muscle mass (ASMM) was assessed with bioelectrical impedance spectroscopy, handgrip strength with JAMAR Smart Hand Dynamometer, muscle function with the Short Physical Performance Battery (SPPB) test, and physical and mental HRQoL with the SF-36 questionnaire. The mean age of participants was 83 (SD=7.4). Using multiple regression models adjusted for sex and age, steps per day and SPPB score explained 38.4 % of the variance in physical HRQoL. Handgrip strength explained 8 % of the variance in mental HRQoL. These findings suggest that QoL improvement programs should include components to improve physical activity, muscle strength and function.

Impact of Participation in a Theatre Programme on Quality of Life among Older Adults with Chronic Conditions: A Pilot Study

2011 ◽  
Vol 18 (4) ◽  
pp. 201-208 ◽  
Author(s):  
Hon Keung Yuen ◽  
Kris Mueller ◽  
Ellise Mayor ◽  
Andres Azuero
Keyword(s):  
Quality Of Life ◽  
Older Adults ◽  
Pilot Study ◽  
Chronic Conditions

scholarly journals Effect of weight loss, exercise, or both on cognition and quality of life in obese older adults

2014 ◽  
Vol 100 (1) ◽  
pp. 189-198 ◽  
Author(s):  
Nicola Napoli ◽  
Krupa Shah ◽  
Debra L Waters ◽  
David R Sinacore ◽  
Clifford Qualls ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Older Adults ◽  
Weight Loss

scholarly journals Multidimensional Benefits of Weight Management in Old Age: The Mobility and Vitality Lifestyle Program

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 840-840
Author(s):  
Steven Albert ◽  
Elizabeth Venditti ◽  
Barbara Nicklas
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Older Adults ◽  
Weight Loss ◽  
Weight Management ◽  
Health Related Quality ◽  
Lifestyle Program ◽  
Related Quality ◽  
Health Related

Abstract The high prevalence of overweight or obesity in older adults is a public health concern because obesity is associated with risk of mobility disability. The benefits of brief community-based lifestyle interventions that promote modest weight loss and increased physical activity are unclear. We assessed the impact of a 13-month lifestyle intervention, the Mobility and Vitality Lifestyle Program (MOVE UP), delivered by community health workers (CHW), on a variety of outcomes, including weight loss, performance-based lower extremity function (Short Physical Performance Battery, SPPB), activity, diet, and health-related quality of life (CDC U48 DP005001). The 32-session behavioral weight management intervention enrolled 303 community-dwelling adults (90.4% of those eligible), who were followed for 12 months (2015-19). Participants completed the program at 26 sites led by 22 CHWs. Participants were age (sd) 67.7 (4.1) and were mostly female (87%). 22.7% were racial minorities. The mean (sd) BMI at baseline was 34.7 (4.7). Median weight loss in the sample was 5% of baseline body weight. SPPB total scores improved by +0.31 units (p &lt; .006), gait speed by +0.04 m/sec (p &lt; .0001), and time to complete chair stands by -0.95 sec (p &lt; .0001). Presenters will assess the effect of MOVE UP on activity, diet, fatigue, and health-related quality of life. A final paper examines implementation of MOVE UP and how site and CHW factors affected outcomes. Findings suggest that promoting healthier eating, weight loss, and physical activity in a community setting is an effective strategy for reducing risk of disability in older adults.

scholarly journals Improvisational Movement to Improve Quality of Life in Older Adults With Early-Stage Dementia: A Pilot Study

2022 ◽  
Vol 3 ◽  
Author(s):  
Deepthi Thumuluri ◽  
Robert Lyday ◽  
Phyllis Babcock ◽  
Edward H. Ip ◽  
Robert A. Kraft ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Older Adults ◽  
Clinical Trial ◽  
Pilot Study ◽  
Social Engagement ◽  
Early Stage ◽  
Brain Network ◽  
Dance Intervention

Alzheimer's disease has profound effects on quality of life, affecting not only cognition, but mobility and opportunities for social engagement. Dance is a form of movement that may be uniquely suited to help maintain quality of life for older adults, including those with dementia, because it inherently incorporates movement, social engagement, and cognitive stimulation. Here, we describe the methods and results of the pilot study for the IMOVE trial (NCT03333837, www.clinicaltrials.gov), a clinical trial designed to use improvisational dance classes to test the effects of movement and social engagement in people with mild cognitive impairment (MCI) or early-stage dementia. The pilot study was an 8-week investigation into the feasibility and potential effects of an improvisational dance intervention on people with MCI or early-stage dementia (PWD/MCI) and their caregivers (CG). The pilot aimed to assess changes in quality of life, balance, mood, and functional brain networks in PWD/MCI and their CG. Participants were recruited as dyads (pairs) that included one PWD/MCI and one CG. Ten total dyads were enrolled in the pilot study with five dyads assigned to the usual care control group and five dyads participating in the dance intervention. The intervention arm met twice weekly for 60 min for 8 weeks. Attendance and quality of life assessed with the Quality of Life in Alzheimer's disease (QoL-AD) questionnaire were the primary outcomes. Secondary outcomes included balance, mood and brain network connectivity assessed through graph theory analysis of functional magnetic resonance imaging (fMRI). Class attendance was 96% and qualitative feedback reflected participants felt socially connected to the group. Increases in quality of life and balance were observed, but not mood. Brain imaging analysis showed increases in multiple brain network characteristics, including global efficiency and modularity. Further investigation into the positive effects of this dance intervention on both imaging and non-imaging metrics will be carried out on the full clinical trial data. Results from the trial are expected in the summer of 2022.

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