scholarly journals Pilot Study Examining the Influence of Potassium Bicarbonate Supplementation on Nitrogen Balance and Whole-Body Ammonia and Urea Turnover Following Short-Term Energy Restriction in Older Men

Nutrients ◽  
2018 ◽  
Vol 10 (5) ◽  
pp. 624
Author(s):  
Lee Margolis ◽  
Lisa Ceglia ◽  
Donato Rivas ◽  
Bess Dawson-Hughes ◽  
Roger Fielding
2021 ◽  
Vol 27 (6) ◽  
pp. S82-S83
Author(s):  
Chinelo C. Okigbo ◽  
Joselyne Tessa Tonleu ◽  
Skand Shekhar ◽  
Helen F. Leka ◽  
Anne E. Kim ◽  
...  

2016 ◽  
Vol 94 (6) ◽  
pp. 2542-2552 ◽  
Author(s):  
P. Moriel ◽  
M. B. Piccolo ◽  
L. F. A. Artioli ◽  
R. S. Marques ◽  
M. H. Poore ◽  
...  

Metabolism ◽  
2007 ◽  
Vol 56 (2) ◽  
pp. 289-295 ◽  
Author(s):  
Lisa A. Kosmiski ◽  
Daniel H. Bessesen ◽  
Sarah A. Stotz ◽  
John R. Koeppe ◽  
Tracy J. Horton

Nutrients ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 386 ◽  
Author(s):  
Edwin Miranda ◽  
Kelly Fuller ◽  
Ryan Perkins ◽  
Paul Beisswenger ◽  
Sarah Farabi ◽  
...  

Advanced glycation end products (AGEs) promote the development of diabetic complications through activation of their receptor (RAGE). Isoforms of soluble RAGE (sRAGE) sequester AGEs and protect against RAGE-mediated diabetic complications. We investigated the effect of an overnight fast on circulating metabolic substrates, hormones, AGEs, and sRAGE isoforms in 26 individuals with type 1 diabetes (T1DM). Blood was collected from 26 young (18–30 years) T1DM patients on insulin pumps before and after an overnight fast. Circulating AGEs were measured via LC-MS/MS and sRAGE isoforms were analyzed via ELISA. Glucose, insulin, glucagon, and eGFRcystatin-c decreased while cortisol increased following the overnight fast (p < 0.05). AGEs (CML, CEL, 3DG-H, MG-H1, and G-H1) decreased (21–58%, p < 0.0001) while total sRAGE, cleaved RAGE (cRAGE), and endogenous secretory RAGE (esRAGE) increased (22–24%, p < 0.0001) following the overnight fast. The changes in sRAGE isoforms were inversely related to MG-H1 (rho = −0.493 to −0.589, p < 0.05) and the change in esRAGE was inversely related to the change in G-H1 (rho = −0.474, p < 0.05). Multiple regression analyses revealed a 1 pg/mL increase in total sRAGE, cRAGE, or esRAGE independently predicted a 0.42–0.52 nmol/L decrease in MG-H1. Short-term energy restriction via an overnight fast resulted in increased sRAGE isoforms and may be protective against AGE accumulation.


2014 ◽  
Vol 145 (2) ◽  
pp. 246-252 ◽  
Author(s):  
Amy J Hector ◽  
George R Marcotte ◽  
Tyler A Churchward-Venne ◽  
Caoileann H Murphy ◽  
Leigh Breen ◽  
...  

Obesity ◽  
2006 ◽  
Vol 14 (5) ◽  
pp. 838-846 ◽  
Author(s):  
Wendy A. M. Blom ◽  
Monica Mars ◽  
Henk F. J. Hendriks ◽  
Lisette C.P.G.M. de Groot ◽  
Annette Stafleu ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Humberto Nicastro ◽  
Nelo Eidy Zanchi ◽  
Claudia Ribeiro da Luz ◽  
Daniela Fojo Seixas Chaves ◽  
Antonio Herbert Lancha

This study aimed to develop an equipment and system of resistance exercise (RE), based on squat-type exercise for rodents, with control of training variables. We developed an operant conditioning system composed of sound, light and feeding devices that allowed optimized RE performance by the animal. With this system, it is not necessary to impose fasting or electric shock for the animal to perform the task proposed (muscle contraction). Furthermore, it is possible to perform muscle function testsin vivowithin the context of the exercise proposed and control variables such as intensity, volume (sets and repetitions), and exercise session length, rest interval between sets and repetitions, and concentric strength. Based on the experiments conducted, we demonstrated that the model proposed is able to perform more specific control of other RE variables, especially rest interval between sets and repetitions, and encourages the animal to exercise through short-term energy restriction and “disturbing” stimulus that do not promote alterations in body weight. Therefore, despite experimental limitations, we believe that this RE apparatus is closer to the physiological context observed in humans.


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