scholarly journals Research Progress of M13 Bacteriophage-Based Biosensors

Nanomaterials ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 1448 ◽  
Author(s):  
Moon ◽  
Choi ◽  
Jeong ◽  
Sohn ◽  
Han ◽  
...  
Keyword(s):  
Genetic Engineering ◽  
Self Assembly ◽  
Recent Progress ◽  
Research Progress ◽  
Homogeneous Distribution ◽  
Sensor Systems ◽  
M13 Bacteriophage ◽  
Mild Conditions ◽  
Sensitivity And Selectivity ◽  
Key Features

Recently, new virus-based sensor systems that operate on M13 bacteriophage infrastructure have attracted considerable attention. These systems can detect a range of chemicals with excellent sensitivity and selectivity. Filaments consistent with M13 bacteriophages can be ordered by highly established forms of self-assembly. This allows M13 bacteriophages to build a homogeneous distribution and infiltrate the network structure of nanostructures under mild conditions. Phage display, involving the genetic engineering of M13 bacteriophages, is another strong feature of the M13 bacteriophage as a functional building block. The numerous genetic modification possibilities of M13 bacteriophages are clearly the key features, and far more applications are envisaged. This paper reviews the recent progress in the application of the M13 bacteriophage self-assembly structures through to sensor systems and discusses future M13 bacteriophage technology.

scholarly journals Template-Free Self-Assembly of Two-Dimensional Polymers into Nano/Microstructured Materials

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3310
Author(s):  
Shengda Liu ◽  
Jiayun Xu ◽  
Xiumei Li ◽  
Tengfei Yan ◽  
Shuangjiang Yu ◽  
...  
Keyword(s):  
Self Assembly ◽  
Recent Progress ◽  
Two Dimensional ◽  
Subsequent Removal ◽  
The Past ◽  
2D Polymers ◽  
Template Free ◽  
Self Assembled ◽  
The Relationship ◽  
Polymer Tubes

In the past few decades, enormous efforts have been made to synthesize covalent polymer nano/microstructured materials with specific morphologies, due to the relationship between their structures and functions. Up to now, the formation of most of these structures often requires either templates or preorganization in order to construct a specific structure before, and then the subsequent removal of previous templates to form a desired structure, on account of the lack of “self-error-correcting” properties of reversible interactions in polymers. The above processes are time-consuming and tedious. A template-free, self-assembled strategy as a “bottom-up” route to fabricate well-defined nano/microstructures remains a challenge. Herein, we introduce the recent progress in template-free, self-assembled nano/microstructures formed by covalent two-dimensional (2D) polymers, such as polymer capsules, polymer films, polymer tubes and polymer rings.

scholarly journals M13 Bacteriophage-Based Self-Assembly Structures and Their Functional Capabilities

2015 ◽  
Vol 12 (3) ◽  
pp. 271-281 ◽  
Author(s):  
Jong-Sik Moon ◽  
Won-Geun Kim ◽  
Chuntae Kim ◽  
Geun-Tae Park ◽  
Jeong Heo ◽  
...  
Keyword(s):  
Self Assembly ◽  
M13 Bacteriophage ◽  
Functional Capabilities

scholarly journals Recent progress in periodic patterning fabricated by self-assembly of colloidal spheres for optical applications

2020 ◽  
Vol 63 (8) ◽  
pp. 1418-1437 ◽  
Author(s):  
Jing Liu ◽  
Xingang Zhang ◽  
Wenqing Li ◽  
Changzhong Jiang ◽  
Ziyu Wang ◽  
...  
Keyword(s):  
Self Assembly ◽  
Recent Progress ◽  
Colloidal Spheres ◽  
Optical Applications

scholarly journals The Report of Marine Life Genomic Research

2018 ◽  
Author(s):  
Guangyi Fan ◽  
Jianwei Chen ◽  
Tao Jin ◽  
Chengcheng Shi ◽  
Xiao Du ◽  
...  
Keyword(s):  
Recent Progress ◽  
Ethical Issues ◽  
Marine Invertebrates ◽  
Marine Species ◽  
White Paper ◽  
Genomic Research ◽  
Research Progress ◽  
Biological Research ◽  
Marine Microorganisms ◽  
Genomics Research

With the continuing development of sequencing technology, genomics has been applied in a variety of biological research areas. In particular, the application of genomics to marine species, which boast a high diversity, promises great scientific and industrial potential. Significant progress has been made in marine genomics especially over the past few years. Consequently, BGI, leveraging its prominent contributions in genomics research, established BGI-Qingdao, an institute specifically aimed at exploring marine genomics. In order to accelerate marine genomics research and related applications, BGI-Qingdao initiated the International Conference on Genomics of the Ocean (ICG-Ocean) to develop international collaborations and establish a focused and coherent global research plan. Last year, the first ICG-Ocean conference was held in Qingdao, China, during which 47 scientists in marine genomics from all over the world reported on their research progress to an audience of about 300 attendees. This year, we would like to build on that success, drafting a report on marine genomics to draw global attention to marine genomics. We summarized the recent progress, proposed future directions, and we would like to enable additional profound insights on marine genomics. Similar to the annual report on plant and fungal research by Kew Gardens, and the White Paper of ethical issues on experimental animals, we hope our first report on marine genomics can provide some useful insights for researchers, funding agencies as well as industry, and that future versions will expand upon the foundation established here in both breadth and depth of knowledge.This report summarizes the recent progress in marine genomics in six parts including: marine microorganisms, marine fungi, marine algae and plants, marine invertebrates, marine vertebrates and genomics-based applications.

scholarly journals Mitochondria-Targeted Self-Assembly of Peptide-Based Nanomaterials

2021 ◽  
Vol 9 ◽  
Author(s):  
Zhen Luo ◽  
Yujuan Gao ◽  
Zhongyu Duan ◽  
Yu Yi ◽  
Hao Wang
Keyword(s):  
Clinical Trials ◽  
Cancer Therapy ◽  
Self Assembly ◽  
Recent Progress ◽  
Assembly Systems ◽  
Targeted Cancer Therapy ◽  
Cancer Treatments ◽  
Self Assembling ◽  
Stimuli Response

Mitochondria are well known to serve as the powerhouse for cells and also the initiator for some vital signaling pathways. A variety of diseases are discovered to be associated with the abnormalities of mitochondria, including cancers. Thus, targeting mitochondria and their metabolisms are recognized to be promising for cancer therapy. In recent years, great efforts have been devoted to developing mitochondria-targeted pharmaceuticals, including small molecular drugs, peptides, proteins, and genes, with several molecular drugs and peptides enrolled in clinical trials. Along with the advances of nanotechnology, self-assembled peptide-nanomaterials that integrate the biomarker-targeting, stimuli-response, self-assembly, and therapeutic effect, have been attracted increasing interest in the fields of biotechnology and nanomedicine. Particularly, in situ mitochondria-targeted self-assembling peptides that can assemble on the surface or inside mitochondria have opened another dimension for the mitochondria-targeted cancer therapy. Here, we highlight the recent progress of mitochondria-targeted peptide-nanomaterials, especially those in situ self-assembly systems in mitochondria, and their applications in cancer treatments.

Biomimetic self-assembly of subcellular structures

2020 ◽  
Vol 56 (60) ◽  
pp. 8342-8354
Author(s):  
Shuying Yang ◽  
Lingxiang Jiang
Keyword(s):  
Self Assembly ◽  
Recent Progress ◽  
Isolated Systems

This article summarizes recent progress on biomimetic subcellular structures and discusses integration of these isolated systems.

scholarly journals A New Heterogeneous Catalyst Obtained via Supramolecular Decoration of Graphene with a Pd2+ Azamacrocyclic Complex

Molecules ◽  
2019 ◽  
Vol 24 (15) ◽  
pp. 2714 ◽  
Author(s):  
Matteo Savastano ◽  
Paloma Arranz-Mascarós ◽  
Maria Paz Clares ◽  
Rafael Cuesta ◽  
Maria Luz Godino-Salido ◽  
...  
Keyword(s):  
Heterogeneous Catalyst ◽  
Self Assembly ◽  
Room Temperature ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Assembly Process ◽  
Efficient Catalyst ◽  
Mild Conditions ◽  
Cross Coupling Reaction ◽  
Green Procedure

A new G-(H2L)-Pd heterogeneous catalyst has been prepared via a self-assembly process consisting in the spontaneous adsorption, in water at room temperature, of a macrocyclic H2L ligand on graphene (G) (G + H2L = G-(H2L)), followed by decoration of the macrocycle with Pd2+ ions (G-(H2L) + Pd2+ = G-(H2L)-Pd) under the same mild conditions. This supramolecular approach is a sustainable (green) procedure that preserves the special characteristics of graphene and furnishes an efficient catalyst for the Cu-free Sonogashira cross coupling reaction between iodobenzene and phenylacetylene. Indeed, G-(H2L)-Pd shows an excellent conversion (90%) of reactants into diphenylacetylene under mild conditions (50 °C, water, aerobic atmosphere, 14 h). The catalyst proved to be reusable for at least four cycles, although decreasing yields down to 50% were observed.

Experimental and numerical evaluation of a genetically engineered M13 bacteriophage with high sensitivity and selectivity for 2,4,6-trinitrotoluene

2019 ◽  
Vol 17 (23) ◽  
pp. 5666-5670 ◽  
Author(s):  
Won-Geun Kim ◽  
Chris Zueger ◽  
Chuntae Kim ◽  
Winnie Wong ◽  
Vasanthan Devaraj ◽  
...  
Keyword(s):  
Quantum Mechanics ◽  
Numerical Evaluation ◽  
High Sensitivity ◽  
Genetically Engineered ◽  
Experimental Results ◽  
Sensor System ◽  
M13 Bacteriophage ◽  
Sensitivity And Selectivity

This study includes the experimental results of a sensitive M13 bacteriophage-based sensor system that are well matched with the quantum mechanics calculation.

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