scholarly journals Magnetic-Plasmonic Heterodimer Nanoparticles: Designing Contemporarily Features for Emerging Biomedical Diagnosis and Treatments

Nanomaterials ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 97 ◽  
Author(s):  
S. Shams ◽  
Mohammad Ghazanfari ◽  
Carolin Schmitz-Antoniak
Keyword(s):  
Drug Delivery ◽  
Photothermal Therapy ◽  
Biomedical Applications ◽  
Recent Progress ◽  
Magnetic Hyperthermia ◽  
Future Research ◽  
Critical Properties ◽  
Interfacial Morphology ◽  
Biomedical Diagnosis ◽  
And Performance

Magnetic-plasmonic heterodimer nanostructures synergistically present excellent magnetic and plasmonic characteristics in a unique platform as a multipurpose medium for recently invented biomedical applications, such as magnetic hyperthermia, photothermal therapy, drug delivery, bioimaging, and biosensing. In this review, we briefly outline the less-known aspects of heterodimers, including electronic composition, interfacial morphology, critical properties, and present concrete examples of recent progress in synthesis and applications. With a focus on emerging features and performance of heterodimers in biomedical applications, this review provides a comprehensive perspective of novel achievements and suggests a fruitful framework for future research.

scholarly journals Recent Advances of Conducting Polymers and Their Composites for Electrochemical Biosensing Applications

2020 ◽  
Vol 11 (4) ◽  
pp. 71 ◽  
Author(s):  
John H. T. Luong ◽  
Tarun Narayan ◽  
Shipra Solanki ◽  
Bansi D. Malhotra
Keyword(s):  
Drug Delivery ◽  
Conducting Polymers ◽  
Biomedical Applications ◽  
Carbon Materials ◽  
Functional Materials ◽  
Glucose Sensing ◽  
Research Trends ◽  
Future Research ◽  
Electrochemical Biosensing ◽  
And Performance

Conducting polymers (CPs) have been at the center of research owing to their metal-like electrochemical properties and polymer-like dispersion nature. CPs and their composites serve as ideal functional materials for diversified biomedical applications like drug delivery, tissue engineering, and diagnostics. There have also been numerous biosensing platforms based on polyaniline (PANI), polypyrrole (PPY), polythiophene (PTP), and their composites. Based on their unique properties and extensive use in biosensing matrices, updated information on novel CPs and their role is appealing. This review focuses on the properties and performance of biosensing matrices based on CPs reported in the last three years. The salient features of CPs like PANI, PPY, PTP, and their composites with nanoparticles, carbon materials, etc. are outlined along with respective examples. A description of mediator conjugated biosensor designs and enzymeless CPs based glucose sensing has also been included. The future research trends with required improvements to improve the analytical performance of CP-biosensing devices have also been addressed.

Lanthanide-doped upconversion nanoparticles complexed with nano-oxide graphene used for upconversion fluorescence imaging and photothermal therapy

2018 ◽  
Vol 6 (4) ◽  
pp. 877-884 ◽  
Author(s):  
Po Li ◽  
Yue Yan ◽  
Binlong Chen ◽  
Pan Zhang ◽  
Siling Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Fluorescence Imaging ◽  
Photothermal Therapy ◽  
Biomedical Applications ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Research Interest ◽  
Upconversion Nanoparticles ◽  
Multifunctional Nanoparticles ◽  
Nano Oxide

In recent years, multifunctional nanoparticles have attracted much research interest in various biomedical applications such as biosensors, diagnosis, and drug delivery systems.

Magnetic Nano-Systems in Drug Delivery and Biomedical Applications

2021 ◽  
pp. 663-695
Author(s):  
Saritha R. Shetty ◽  
Archana Upadhya
Keyword(s):  
Magnetic Field ◽  
Drug Delivery ◽  
Targeted Delivery ◽  
Biomedical Applications ◽  
Magnetic Hyperthermia ◽  
Effective Utilization ◽  
Engineering Sciences ◽  
Nanoscale Science ◽  
The Magnetic Field ◽  
Unique Ability

Nanotechnology is that sphere of technology that involves the participation of biology, chemistry, physics, and engineering sciences. Nanoscale science defines the chemistry and physics of structures lying in the range of 1-100 nm. Among the nanosystems researched, magnetic nanosystems are highlighted due their unique ability, which enables their targeting to specific locations on application of an external magnetic field. The exhibited property of these magnetic nanosystems being super-paramagnetism, there is no retention of magnetic property on removal of the magnetic field, thus enabling a reversion of the targeting process. For effective utilization of these nanosystems, they should be reduced to nanosizes, layered with biocompatible entities, stabilized, and functionalized. In the chapter, synthesis and functionalization and stabilization are elucidated. The biomedical applications such as targeted delivery, MRI, magnetic hyperthermia, tissue engineering, gene delivery, magnetic immunotherapy, magnetic detoxification, and nanomagnetic actuation are discussed.

Multiple gold nanorods@hierarchically porous silica nanospheres for efficient multi-drug delivery and photothermal therapy

2017 ◽  
Vol 5 (8) ◽  
pp. 1642-1649 ◽  
Author(s):  
Nan Li ◽  
Dechao Niu ◽  
Xiaobo Jia ◽  
Jianping He ◽  
Yu Jiang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Gold Nanorods ◽  
Photothermal Therapy ◽  
Biomedical Applications ◽  
Porous Silica ◽  
Photothermal Effect ◽  
Silica Nanospheres ◽  
Hierarchically Porous ◽  
Silica Nanocomposites ◽  
Hierarchically Porous Structure

Gold-based silica nanocomposites with hierarchically porous structure, as well as excellent photothermal effect, have shown great potentials in biomedical applications.

scholarly journals Agricultural and Biomedical Applications of Chitosan-Based Nanomaterials

Nanomaterials ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 1903 ◽  
Author(s):  
Subhani Bandara ◽  
Hongbo Du ◽  
Laura Carson ◽  
Debra Bradford ◽  
Raghava Kommalapati
Keyword(s):  
Foodborne Pathogens ◽  
Water Availability ◽  
Photothermal Therapy ◽  
Biomedical Applications ◽  
Chitosan Nanoparticles ◽  
Agricultural Practices ◽  
Mechanisms Of Action ◽  
Future Research ◽  
Limited Attention ◽  
Sustainable Agricultural Practices

Chitosan has emerged as a biodegradable, nontoxic polymer with multiple beneficial applications in the agricultural and biomedical sectors. As nanotechnology has evolved as a promising field, researchers have incorporated chitosan-based nanomaterials in a variety of products to enhance their efficacy and biocompatibility. Moreover, due to its inherent antimicrobial and chelating properties, and the availability of modifiable functional groups, chitosan nanoparticles were also directly used in a variety of applications. In this review, the use of chitosan-based nanomaterials in agricultural and biomedical fields related to the management of abiotic stress in plants, water availability for crops, controlling foodborne pathogens, and cancer photothermal therapy is discussed, with some insights into the possible mechanisms of action. Additionally, the toxicity arising from the accumulation of these nanomaterials in biological systems and future research avenues that had gained limited attention from the scientific community are discussed here. Overall, chitosan-based nanomaterials show promising characteristics for sustainable agricultural practices and effective healthcare in an eco-friendly manner.

RECENT ADVANCES IN GRAPHENE-BASED NANOMATERIALS FOR BIOMEDICAL APPLICATIONS

Nano LIFE ◽  
2012 ◽  
Vol 02 (01) ◽  
pp. 1230001 ◽  
Author(s):  
HONGQIAN BAO ◽  
YONGZHENG PAN ◽  
LIN LI
Keyword(s):  
Drug Delivery ◽  
Gene Delivery ◽  
Physicochemical Properties ◽  
Biomedical Applications ◽  
Recent Progress ◽  
Cancer Therapies ◽  
Two Dimensional ◽  
Potential Applications ◽  
First Time ◽  
Potential Cancer

Graphene, a two-dimensional nanomaterial reported for the first time in 2004, has been widely investigated for its novel physicochemical properties and potential applications. This review selectively summarizes the recent progress in using graphene-based nanomaterials for various biomedical applications. In particular, graphene-based sensors and biosensors, which are classified according to different sensing mechanisms and targets, are thoroughly discussed. Next, the utilization of graphene as nanocarriers for drug delivery, gene delivery and nanomedicine are demonstrated for potential cancer therapies. Finally, other graphene-based matrices, nanoscaffolds, and composites, which are used in bioapplications, are presented, followed by conclusions and perspective.

Bioadhesive Films AS Drug Delivery Systems

2020 ◽  
Vol 10 ◽  
Author(s):  
Inderbir Singh ◽  
Debabrata Ghosh Dastidar ◽  
Dipanjan Ghosh ◽  
Abhijit Sengupta ◽  
Tolulope O. Ajala ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Transdermal Delivery ◽  
Dosage Forms ◽  
Future Research ◽  
Basic Principles ◽  
Drug Molecules ◽  
And Performance ◽  
Current Area ◽  
Product Outcome ◽  
Novel Drug

: Bioadhesive films are considered as a novel drug delivery system which provides improved therapy and better patient compliance than conventional dosage forms. The type and concentration of polymer or the blend of polymers used are important factors influencing the properties of bioadhesive films and influencingthe product outcome and performance. But the modification of available polymers to synthesize polymers with improved properties is the current area of research. Furthermore, addressing the challenges in formulating bioadhesive films for transdermal delivery of a variety of different classes of drug molecules is the frontier for future research. With the advancement of synthetic chemistry and the development of newer technology like 3D printing, more and more studies are going on bioadhesive films that have opened up a bunch of opportunities in this field of research. This article reviews the current advancements in developingbio-adhesive films and provides basic principles that will be helpful to overcome the difficulties that are associated with the design of formulation.

scholarly journals Alginate Modification and Lectin-Conjugation Approach to Synthesize the Mucoadhesive Matrix

2021 ◽  
Vol 11 (24) ◽  
pp. 11818
Author(s):  
Arlina Prima Putri ◽  
Francesco Picchioni ◽  
Sri Harjanto ◽  
Mochamad Chalid
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Biomedical Applications ◽  
Enzymatic Degradation ◽  
Recent Progress ◽  
Graft Copolymerization ◽  
Specific Site ◽  
3D Bioprinting ◽  
Future Studies ◽  
New Perspective

Alginates are natural anionic polyelectrolytes investigated in various biomedical applications, such as drug delivery, tissue engineering, and 3D bioprinting. Functionalization of alginates is one possible way to provide a broad range of requirements for those applications. A range of techniques, including esterification, amidation, acetylation, phosphorylation, sulfation, graft copolymerization, and oxidation and reduction, have been implemented for this purpose. The rationale behind these investigations is often the combination of such modified alginates with different molecules. Particularly promising are lectin conjugate macromolecules for lectin-mediated drug delivery, which enhance the bioavailability of active ingredients on a specific site. Most interesting for such application are alginate derivatives, because these macromolecules are more resistant to acidic and enzymatic degradation. This review will report recent progress in alginate modification and conjugation, focusing on alginate-lectin conjugation, which is proposed as a matrix for mucoadhesive drug delivery and provides a new perspective for future studies with these conjugation methods.

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