scholarly journals Novel Concept of Micro Patterned Micro Titer Plates Fabricated via UV-NIL for Automated Neuronal Cell Assay Read-Out

Nanomaterials ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 902
Author(s):  
Mirko Lohse ◽  
Manuel W. Thesen ◽  
Anja Haase ◽  
Martin Smolka ◽  
Nerea Briz Iceta ◽  
...  
Keyword(s):  
Nanoimprint Lithography ◽  
Open Channel ◽  
Neuronal Cell ◽  
Microfluidic System ◽  
Deep Insight ◽  
Uv Curable ◽  
Cell Compatibility ◽  
Novel Concept ◽  
The Given ◽  
Insight Into

The UV-nanoimprint lithography(UV-NIL) fabrication of a novel network of micron-sized channels, forming an open channel microfluidic system is described. Details about the complete manufacturing process, from mastering to fabrication in small batches and in high throughput with up to 1200 micro titer plates per hour is presented. Deep insight into the evaluation of a suitable UV-curable material, mr-UVCur26SF is given, presenting cytotoxic evaluation, cell compatibility tests and finally a neuronal assay. The results indicate how the given pattern, in combination with the resist, paves the way to faster, cheaper, and more reliable drug screening.

Mobile-Friendly Dashboards to Display Associations Between Cited-by and Similar Journals on Mobile Health Research: A Bibliometric Study (Preprint)

2018 ◽  
Author(s):  
Tsair-Wei Chien ◽  
Hsien-Yi Wang ◽  
Yang Shao ◽  
Willy Chou
Keyword(s):  
Social Network ◽  
Mobile Health ◽  
Health Research ◽  
Similarity Criteria ◽  
Network Density ◽  
Deep Insight ◽  
Density Indices ◽  
The Subject ◽  
The Given ◽  
Insight Into

BACKGROUND Researchers often spend a great deal of time and effort retrieving related journals for their studies and submissions. Authors often designate one article and then retrieve other articles that are related to the given one using PubMed’s service for finding cited-by or similar articles. However, to date, none present the association between cited-by and similar journals related to a given journal. Authors need one effective and efficient way to find related journals on the topic of mobile health research. OBJECTIVE This study aims (1) to show the related journals for a given journal by both cited-by and similarity criteria; (2) to present the association between cited-by and similarity journals related to a given journal; (3) to inspect the patterns of network density indices among clusters classified by social network analysis (SNA); (4) to investigate the feature of Kendall's coefficient(W) of concordance. METHODS We obtained 676 abstracts since 2013 from Medline based on the keywords of ("JMIR mHealth and uHealth"[Journal]) on June 30, 2018, and plotted the clusters of related journals on Google Maps by using MS Excel modules. The features of network density indices were examined. The Kendall coefficient (W) was used to assess the concordance of clusters across indices. RESULTS This study found that (1) the journals related to JMIR mHealth and uHealth are easily presented on dashboards; (2) a mild association(=0.14) exists between cited-by and similar journals related to JMIR mHealth and uHealth; (3) the median Impact Factor were 3.37 and 2.183 based on the representatives of top ten clusters grouped by the cited-by and similar journals, respectively; (4) all Kendall’s coefficients(i.e., 0.82, 0.89, 0.92, and 0.75) for the four sets of density centrality have a statistically significant concordance (p < 0.05). CONCLUSIONS SNA provides deep insight into the relationships of related journals to a given journal. The results of this research can provide readers with a knowledge and concept diagram to use with future submissions to a given journal in the subject category of Mobile Health Research. CLINICALTRIAL Not available

scholarly journals Constitutional Dilemma of Pakistan: 1947 -1956

2018 ◽  
Vol III (I) ◽  
pp. 1-9
Author(s):  
Muhammad Rizwan ◽  
Manzoor Ahmad ◽  
Syed Asif Anwar Bukhari
Keyword(s):  
Human Rights ◽  
Political Leadership ◽  
Deep Insight ◽  
Constitutional Development ◽  
The World ◽  
Refugee Problem ◽  
The Right ◽  
The Given ◽  
The Relationship ◽  
Insight Into

Soon after its creation, Pakistan confronted many issues including refugee problem, scarcity of able political leadership, absence of mutual consensus between both wings of the country and confusing nature of the relationship between Islam and state etc. took almost nine years to frame the permanent constitution for Pakistan. Constitution, the basic document of a state, determines the shape of its laws, structure of governance and system of rights and duties. The effectiveness of a constitution is judged by its practicability in the given area where it is enforced by the state machinery. Although, all civilized states of the world do possess a constitution, yet a good constitution is one which must protect the basic human rights by ensuring the independence of judiciary. Due to countless hurdles at the beginning of its journey, Pakistan’s constitutional development in the right direction could not take place. The main objective of the present study is to provide deep insight into the events and factors causing a delay in the constitution-making for the newly created state of Pakistan. The various events which took place from 1947 to 1956 have been analyzed in a subtle way.

A Data Visualization Dashboard like a Game to Show Associations Between Cited-by and Similar Journals related to JMIR Serious Games: A Bibliometric Study (Preprint)

2018 ◽  
Author(s):  
Tsair-Wei Chien ◽  
Hsien-Yi Wang ◽  
Yang Shao ◽  
Willy Chou
Keyword(s):  
Social Network ◽  
Social Network Analysis ◽  
Network Analysis ◽  
Serious Games ◽  
Deep Insight ◽  
The Past ◽  
The Given ◽  
Strength Of Association ◽  
Insight Into ◽  
The U.S

BACKGROUND Over 47,703 articles were found on Pubmed.com by searching for the keyword “association between[Title]” in the past. However, to date, none present the association between cited-by and similar journals related to a given journal. Authors need one effective and efficient way to find journals related to a specific journal. The strength of association between cited-by and similar journals for a given journal is required to report. OBJECTIVE This study aims (1) to present the feature of a given journal about their keyword topics and international author collaborations; (2) to show the cited-by and similar journals related to the given journal; (3) to investigate the association between their cited-by and similar journals. METHODS We obtained 85 abstracts since 2013 from Medline based on the keywords of ("JMIR Serious Games[Journal]) on June 30, 2018, and plotted the clusters, including (i) international author collaborations, (ii) keyword topics, (iii)cited-by and similar journals related to JMIR Serious Games(JSG), and (iv) association between cited-by and similar journals, on Google Maps by using social network analysis(SNA). RESULTS This study found that (1) the most number of papers are from the U.S.( 28, 32.9%) and the U.K. (11,12.9 %), the most frequently used keywords are serious games and video games; (2) the top two journals for cited-by and similar journals, respectively, are (i) JMIR mHealth uHealth(IF=4.541), J Med Internet Res (IF=4.671) and (ii) Games Health J (IF= 2.019), J Med Internet Res (IF=4.671); (3) a mild association(=0.14) exists between cited-by and similar journals related to JSG. CONCLUSIONS SNA provides deep insight into the relationships of related journals to a given journal. The results of this research can provide readers with a knowledge and concept diagram to use with future manuscript submissions to JSG. CLINICALTRIAL Not available

scholarly journals Finding related journals online on Google Maps: a bibliometric study based on PubMed�s service of locating similar articles (Preprint)

2018 ◽  
Author(s):  
Tsair-Wei Chien ◽  
Hsien-Yi Wang ◽  
Yu Chang ◽  
Willy Chou
Keyword(s):  
Internet Research ◽  
Impact Factors ◽  
Network Density ◽  
Journal Online ◽  
Deep Insight ◽  
Google Maps ◽  
Density Indices ◽  
The Subject ◽  
The Given ◽  
Insight Into

BACKGROUND Researchers often spend a great deal of time and effort retrieving related articles for their studies and submissions. Article authors often designate one article and then retrieve other articles that are related to the given one using PubMed’s service for finding similar articles. However, to date, none present the pattern seen in selecting related journals as similar to a given journal. Authors need one effective and efficient way to find similar journals to the designated journal selected for a study. OBJECTIVE The aim of this study is to (1) show the location of related journals for a given journal online using Google Maps; (2) to verify the change in those related journals, along with their respective impact factors; and (3) to inspect the features of network density indices among clusters separated by social network analysis (SNA). METHODS Using downloaded abstracts from the Medline library for the Journal of Medical Internet Research (JMIR) published in 2007 and 2017, we plotted the clusters of related journals on Google Maps by using MS Excel modules, and we compared the features of network density indices. The Kendall coefficient (W) was used to assess the concordance of clusters across indices. RESULTS This study found that (1) the journals related to JMIR are easily presented on Google Maps; (2) no difference was found in the medians of impact factor on related journals between the years of 2007 and 2017 (3.01(2.62–3.40) and 2.55(2.29–2.82), respectively); and (3) All but the ratio indices in 2007 have a statistically significant concordance (p < 0.05). CONCLUSIONS SNA provides deep insight into the relationships of related journals to a given journal. The results of this research can provide readers with a knowledge and concept diagram to use with future submissions to a given journal in the subject category of medical informatics.

Thousands of human sequences provide deep insight into single genomes

Nature ◽  
2020 ◽  
Vol 581 (7809) ◽  
pp. 385-386
Author(s):  
Deanna M. Church
Keyword(s):  
Deep Insight ◽  
Insight Into

Deep insight into the charge transfer interactions in 1,2,4,5-tetracyanobenzene-phenazine cocrystal

2021 ◽  
Author(s):  
Hongnan Wu ◽  
Yajing Sun ◽  
Lingjie Sun ◽  
Liwei Wang ◽  
Xiaotao Zhang ◽  
...  
Keyword(s):  
Charge Transfer ◽  
Deep Insight ◽  
Insight Into

scholarly journals Surface contact behavior of functionally graded thermoelectric materials indented by a conducting punch

2021 ◽  
Author(s):  
Xiaojuan Tian ◽  
Yueting Zhou ◽  
Lihua Wang ◽  
Shenghu Ding
Keyword(s):  
Thermoelectric Materials ◽  
Singular Integral Equations ◽  
Damage Mechanism ◽  
Functionally Graded ◽  
Deep Insight ◽  
Displacement Fields ◽  
Thermoelectric Effects ◽  
Homogeneous Solutions ◽  
The Fourier Transform ◽  
Insight Into

AbstractThe contact problem for thermoelectric materials with functionally graded properties is considered. The material properties, such as the electric conductivity, the thermal conductivity, the shear modulus, and the thermal expansion coefficient, vary in an exponential function. Using the Fourier transform technique, the electro-thermo-elastic problems are transformed into three sets of singular integral equations which are solved numerically in terms of the unknown normal electric current density, the normal energy flux, and the contact pressure. Meanwhile, the complex homogeneous solutions of the displacement fields caused by the gradient parameters are simplified with the help of Euler’s formula. After addressing the non-linearity excited by thermoelectric effects, the particular solutions of the displacement fields can be assessed. The effects of various combinations of material gradient parameters and thermoelectric loads on the contact behaviors of thermoelectric materials are presented. The results give a deep insight into the contact damage mechanism of functionally graded thermoelectric materials (FGTEMs).

A novel concept for evaluation of biofilm adhesion strength by applying tensile force and shear force

1996 ◽  
Vol 34 (5-6) ◽  
pp. 201-211 ◽  
Author(s):  
Akiyoshi Ohashi ◽  
Hideki Harada
Keyword(s):  
Adhesion Strength ◽  
Shear Force ◽  
Growth Stage ◽  
Open Channel ◽  
Tensile Force ◽  
Cavity Formation ◽  
Channel Reactor ◽  
Flat Surfaces ◽  
Novel Concept ◽  
Gravity Test

A novel methodology is proposed in this study to evaluate biofilm adhesion strength in two different ways: by measuring detached biomass caused by tensile force and by shear force. Tensile force was provided by centrifuging biofilm-attached plates installed on rotary tables. Shear force was provided by colliding biofilm-attached plates by gravity. Test biofilms consisting of denitrifiers were formed on the flat surfaces of square (25 cm2) plates that had been submerged in a rectangular open-channel reactor. The detachment tests revealed that, although biofilm adhesion strength was relatively high at the earlier growth stage, it drastically decreased at the later stage. The most weakened location toward biofilm depth was observed at the substratum surface, at which the adhesion strength by tensile force dropped from a several Pa to below 1 Pa as biofilms became aged. The adhesion strength by shear force was all the time more than 100 times as large as that by tensile force, even though having a similar behavior. The proportion of cavity, i.e., biofilm-absent area at the biofilm/substratum interface, increased as biofilms became mature. Cavity formation was strongly responsible for lessening the adhesion strength. It is suggested that biofilm slough-off is caused by the decline of adhesion strength by tensile force rather than by shear force.

Mechanistic insights into the allylic oxidation of aliphatic compounds by tetraamido iron(v) species: A C–H vs. O–H bond activation

2020 ◽  
Vol 44 (44) ◽  
pp. 19103-19112
Author(s):  
Monika ◽  
Azaj Ansari
Keyword(s):  
Comparative Study ◽  
Bond Activation ◽  
Iron Complex ◽  
Catalytic Reactions ◽  
Allylic Oxidation ◽  
Deep Insight ◽  
Aliphatic Compounds ◽  
High Valent ◽  
Insight Into

This work is based on a deep insight into a comparative study of C–H vs. O–H bond activation of allylic compound by the high valent iron complex. Our theoretical findings can help to design catalysts with better efficiency for catalytic reactions.

Conceptualizing Small and Medium-Sized Smart Cities in the Mediterranean Region

2019 ◽  
Vol 8 (4) ◽  
pp. 17-41
Author(s):  
Maria Panagiotopoulou ◽  
Margarita Kokla ◽  
Anastasia Stratigea
Keyword(s):  
Empirical Evidence ◽  
Smart City ◽  
Mediterranean Region ◽  
Smart Cities ◽  
Semantic Interoperability ◽  
Spatial Context ◽  
Deep Insight ◽  
Key Drivers ◽  
The Mediterranean ◽  
Insight Into

Despite the remarkable interest in smart cities, noticed during the last decade, a consistent comprehension of the concept is not yet fully realized. Various definitions, ranging from exclusively technology-oriented perceptions to broader views, have been introduced, establishing a definitional polyphony and causing lack of semantic interoperability. Empirical evidence witnesses the prevalence of technology-pushed smart city initiatives as well as their failure to meet expectations in several urban domains. When planning “smart,” the relevance of ICT and their applications should be in alignment with spatial and other urban peculiarities and sub-systems' interactions, implying the need for getting deep insight into the city's ontology. The paper focuses on the extension/enrichment of an existing smart city ontology, with concepts and relationships stemming from Mediterranean small and medium-sized cities, in an attempt to outline their main key drivers and their interrelationships and fully grasp the smart city concept in the particular spatial context.

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