scholarly journals Recent Progress Concerning the N-arylation of Indoles

Molecules ◽  
2021 ◽  
Vol 26 (16) ◽  
pp. 5079
Author(s):  
Petr Oeser ◽  
Jakub Koudelka ◽  
Artem Petrenko ◽  
Tomáš Tobrman
Keyword(s):  
Transition Metal ◽  
Recent Progress ◽  
Final Section ◽  
State Of The Art ◽  
Biologically Active ◽  
Short Introduction ◽  
Metal Free ◽  
Current State ◽  
Palladium Catalyzed

This review summarizes the current state-of-the-art procedures in terms of the preparation of N-arylindoles. After a short introduction, the transition-metal-free procedures available for the N-arylation of indoles are briefly discussed. Then, the nickel-catalyzed and palladium-catalyzed N-arylation of indoles are both discussed. In the next section, copper-catalyzed procedures for the N-arylation of indoles are described. The final section focuses on recent findings in the field of biologically active N-arylindoles.

Five-Membered Hetarene N-Oxides: Recent Advances in Synthesis and Reactivity

Synthesis ◽  
2021 ◽  
Author(s):  
Leonid Fershtat ◽  
Fedor Teslenko
Keyword(s):  
Transition Metal ◽  
Medicinal Chemistry ◽  
Materials Science ◽  
State Of The Art ◽  
Short Review ◽  
Advanced Materials ◽  
Metal Free ◽  
Recent Advances ◽  
Application Potential ◽  
Metal Catalyzed

Five-membered heterocyclic N-oxides attracted special attention due to their strong application potential in medicinal chemistry and advanced materials science. In this regard, novel methods for their synthesis and functionalization are constantly required. In this short review, recent state-of-the-art achievements in the chemistry of isoxazoline N-oxides, 1,2,3-triazole 1-oxides and 1,2,5-oxadiazole 2-oxides are briefly summarized. Main routes to transition-metal-catalyzed and metal-free functionalization protocols along with mechanistic considerations are outlined. Transformation patterns of the hetarene N-oxide rings as precursors to other nitrogen heterocyclic systems are also presented.

Metal-Free Catalytic Aromatic C–H Borylation

Synlett ◽  
2020 ◽  
Vol 31 (19) ◽  
pp. 1857-1861
Author(s):  
Hua Zhang ◽  
Li Wang
Keyword(s):  
Transition Metal ◽  
Recent Progress ◽  
Rapid Development ◽  
Transition Metal Catalysis ◽  
Mechanistic Studies ◽  
Metal Catalysis ◽  
Promising Alternative ◽  
Metal Free ◽  
History Of ◽  
Near Future

In recent decades, C–H borylation has undergone rapid development and has become one of the most important and efficient methods for the synthesis of organoboron compounds. Although transition-metal catalysis dominates C–H borylation, the metal-free approach has emerged as a promising alternative strategy. This article briefly summarizes the history of metal-free aromatic C–H borylation, including early reports on electrophilic C–H borylation and recent progress in metal-free catalytic intermolecular C–H borylation; it also highlights our recent work on BF3·Et2O-catalyzed C2–H borylation of hetarenes. Despite these recent advances, comprehensive mechanistic studies on various metal-free catalytic aromatic C–H borylations and novel processes with a wider substrate scope are eagerly expected in the near future.

scholarly journals Recent progress in transition-metal-free functionalization of allenamides

RSC Advances ◽  
2020 ◽  
Vol 10 (60) ◽  
pp. 36818-36827
Author(s):  
Xiaoxiao Li ◽  
Yongchun Liu ◽  
Na Ding ◽  
Xiaoju Tan ◽  
Zhigang Zhao
Keyword(s):  
Transition Metal ◽  
Recent Progress ◽  
Complex Molecules ◽  
Metal Free ◽  
Powerful Approach

Recent progress in transition-metal-free functionalization of allenamides is reviewed, providing a powerful approach to rapidly access complex molecules.

The Survey on Applications of Information Hiding Technology in E-Commerce Security

2013 ◽  
Vol 433-435 ◽  
pp. 1866-1870
Author(s):  
Yan Mei Chai ◽  
Su Wen Zhu ◽  
Wen Ying Han
Keyword(s):  
Information Security ◽  
Research And Development ◽  
Information Hiding ◽  
Recent Progress ◽  
State Of The Art ◽  
Development Trends ◽  
Security Sector ◽  
Basic Model ◽  
Current State

The booming e-commerce industry is suffering from serious information security problems. As a potential and effective security solution, information hiding technology has been widely applied in many fields and drawn unprecedented attention. Based on our research, this paper provides a survey on the current state of the art information hiding technology, mainly covering the fundamental concepts, basic model, the recent progress of information hiding methods and its applications in e-commerce security sector. At last, possible research and development trends of information hiding technology are discussed.

State-of-the-art catechol porphyrin COF catalyst for chemical fixation of carbon dioxide via cyclic carbonates and oxazolidinones

2016 ◽  
Vol 6 (15) ◽  
pp. 6152-6158 ◽  
Author(s):  
Vitthal Saptal ◽  
Digambar Balaji Shinde ◽  
Rahul Banerjee ◽  
Bhalchandra M. Bhanage
Keyword(s):  
Carbon Dioxide ◽  
Transition Metal ◽  
State Of The Art ◽  
Value Added ◽  
Chemical Fixation ◽  
Cyclic Carbonates ◽  
Metal Free ◽  
Highly Porous ◽  
Fixation Of Carbon Dioxide

A highly porous, crystalline catechol porphyrin COF was synthesized and applied as an organocatalyst for the fixation of carbon dioxide to synthesize value-added chemicals such as cyclic carbonates and oxazolidinones under solvent and transition-metal-free conditions.

scholarly journals Ensuring Confidentiality of Geocoded Health Data: Assessing Geographic Masking Strategies for Individual-Level Data

2014 ◽  
Vol 2014 ◽  
pp. 1-14 ◽  
Author(s):  
Paul A. Zandbergen
Keyword(s):  
Public Health ◽  
Recent Progress ◽  
State Of The Art ◽  
Random Perturbation ◽  
Health Data ◽  
The Other ◽  
Individual Level ◽  
Current State ◽  
Level Data ◽  
Geocoded Data

Public health datasets increasingly use geographic identifiers such as an individual’s address. Geocoding these addresses often provides new insights since it becomes possible to examine spatial patterns and associations. Address information is typically considered confidential and is therefore not released or shared with others. Publishing maps with the locations of individuals, however, may also breach confidentiality since addresses and associated identities can be discovered through reverse geocoding. One commonly used technique to protect confidentiality when releasing individual-level geocoded data is geographic masking. This typically consists of applying a certain amount of random perturbation in a systematic manner to reduce the risk of reidentification. A number of geographic masking techniques have been developed as well as methods to quantity the risk of reidentification associated with a particular masking method. This paper presents a review of the current state-of-the-art in geographic masking, summarizing the various methods and their strengths and weaknesses. Despite recent progress, no universally accepted or endorsed geographic masking technique has emerged. Researchers on the other hand are publishing maps using geographic masking of confidential locations. Any researcher publishing such maps is advised to become familiar with the different masking techniques available and their associated reidentification risks.

Synergy between experimental and theoretical methods in the exploration of homogeneous transition metal catalysis

2014 ◽  
Vol 43 (29) ◽  
pp. 11093-11105 ◽  
Author(s):  
D. Lupp ◽  
N. J. Christensen ◽  
P. Fristrup
Keyword(s):  
Transition Metal ◽  
Reaction Mechanisms ◽  
State Of The Art ◽  
Transition Metal Catalysis ◽  
Metal Catalysis ◽  
Theoretical Methods ◽  
Current State

In this Perspective, we will focus on the use of both experimental and theoretical methods in the exploration of reaction mechanisms in homogeneous transition metal catalysis. The current state-of-the-art is highlighted using examples from the literature with particular focus on the synergy between experiment and theory.

Uncovering Multifaceted Iodonium Ylides: Versatile Reactivity Enables Cyclization of Simple Arylamines

Synlett ◽  
2018 ◽  
Vol 29 (18) ◽  
pp. 2337-2341 ◽  
Author(s):  
Yao Wang ◽  
Liang Zhang
Keyword(s):  
Transition Metal ◽  
Recent Progress ◽  
Chemical Properties ◽  
Historical Background ◽  
Chemical Transformations ◽  
Metal Free ◽  
Reaction Discovery ◽  
Iodonium Ylides

Iodonium ylides can undergo cyclization with a simple tertiary arylamine to afford N-heterocyclic products in a transition-metal-free approach in the absence of an additional initiator/oxidant. The ­inherent reactivity uncovered in this transformation is fundamentally different from known chemical properties of iodonium ylide compounds, thus providing a new opportunity for the further exploration of iodonium ylide-based chemical transformations. This Synpacts article describes the historical background of iodonium ylide chemistry and highlights recent progress disclosed by our work.1 Introduction2 The Strategy for New Reaction Discovery3 Application to Cyclization of Tertiary Arylamines4 Conclusion and Perspectives

Sign in / Sign up

Export Citation Format

Share Document