scholarly journals Insecticidal Activity and Free Radical Scavenging Properties of Isolated Phytoconstituents from the Saudi Plant Nuxia oppositifolia (Hochst.)

Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 914
Author(s):  
Shaza M. Al-Massarani ◽  
Ali A. El-Gamal ◽  
Adnan J. Al-Rehaily ◽  
Ebtesam S. Al-Sheddi ◽  
Mai M. Al-Oqail ◽  
...  
Keyword(s):  
Free Radical ◽  
Insecticidal Activity ◽  
Radical Scavenging ◽  
Positive Control ◽  
Free Radical Scavenging ◽  
Alcoholic Extract ◽  
Chemical Structures ◽  
Aerial Parts ◽  
Radical Scavenging Properties ◽  
Promising Source

Chromatographic purification of the alcoholic extract from the aerial parts of the Saudi plant Nuxia oppositifolia (Hochst.), Benth., resulted in five isolated phenolic compounds. Two flavones, hispidulin (1) and jaceosidin (2), and the phenylethanoid glycosides, verbascoside (3), isoverbascoside (4), and conandroside (5), were identified and their chemical structures were determined by spectroscopic analyses. The insecticidal activity of compounds 1 and 2, in addition to 11 compounds isolated in a previous research (6–16), was evaluated against the Yellow Fever mosquito, Aedes aegypti. Four compounds displayed adulticidal activity with LD50 values of 2–2.3 μg/mosquito. Free radical scavenging properties of the plant extracts and compounds (1–5) were evaluated by measuring the 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) and 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonate radical cation (ABTS•+) scavenging activity. All compounds exhibited notable activity, compared with the positive control, l-Ascorbic acid. This study suggests that N. oppositifolia could be a promising source of secondary metabolites, some with lethal adulticidal effect against Ae. aegypti.

scholarly journals Antibacterial and free-radical-scavenging properties of Stachys schtschegleevii (Lamiaceae)

2010 ◽  
Vol 62 (4) ◽  
pp. 941-945 ◽  
Author(s):  
Malvika Abichandani ◽  
Lutfun Nahar ◽  
Poonam Singh ◽  
Rohit Chitnis ◽  
H. Nazemiyeh ◽  
...  
Keyword(s):  
Free Radical ◽  
Bacterial Infections ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Positive Control ◽  
Free Radical Scavenging ◽  
Meoh Extract ◽  
Inflammatory Conditions ◽  
Iranian Traditional Medicine ◽  
Radical Scavenging Properties

Stachys schtschegleevii Sosn. (Lamiaceae alt. Labiatae) is one of 34 Stachys species found in Iran, and is morphologically similar to Stachys inflata. This plant has been used in the Iranian traditional medicine as a remedy for bacterial infections, rheumatic fever and other inflammatory conditions. The n-hexane, dichloromethane (DCM) and methanol (MeOH) extracts of the non-flowering aerial parts of this plant were assessed for their antibacterial and freeradical- scavenging activities using the micro-titer-based antimicrobial assay incorporating resazurin as an indicator of cell growth and the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, respectively. While the n-hexane extract did not show any free-radical-scavenging activity, the MeOH extract showed the highest level of activity with a RC50 value of 2.94 x 10-2 mg/mL, which was about ten-fold less active than the positive control Trolox? (RC50 = 2.60 x 10-3 mg/mL). None of the extracts showed any antibacterial property against Bacillus cereus and B. subtilis at test concentrations. However, all extracts were active against ampicillin-resistant Escherichia coli and Staphylococcus aureus. The MeOH extract was the most potent (MIC range 1.56-6.25 mg/mL) among the extracts and was most active against ampicillin-resistant E. coli (MIC = 1.56 mg/mL).

scholarly journals Chemical Analysis, Toxicity Study, and Free-Radical Scavenging and Iron-Binding Assays Involving Coffee (Coffea arabica) Extracts

Molecules ◽  
2021 ◽  
Vol 26 (14) ◽  
pp. 4169
Author(s):  
Nuntouchaporn Hutachok ◽  
Pimpisid Koonyosying ◽  
Tanachai Pankasemsuk ◽  
Pongsak Angkasith ◽  
Chaiwat Chumpun ◽  
...  
Keyword(s):  
Free Radical ◽  
Mononuclear Cells ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Chemical Compositions ◽  
Coffee Bean ◽  
Dependent Manner ◽  
Roasted Coffee ◽  
Instant Coffee ◽  
Radical Scavenging Properties

We aimed to analyze the chemical compositions in Arabica coffee bean extracts, assess the relevant antioxidant and iron-chelating activities in coffee extracts and instant coffee, and evaluate the toxicity in roasted coffee. Coffee beans were extracted using boiling, drip-filtered and espresso brewing methods. Certain phenolics were investigated including trigonelline, caffeic acid and their derivatives, gallic acid, epicatechin, chlorogenic acid (CGA) and their derivatives, p-coumaroylquinic acid, p-coumaroyl glucoside, the rutin and syringic acid that exist in green and roasted coffee extracts, along with dimethoxycinnamic acid, caffeoylarbutin and cymaroside that may be present in green coffee bean extracts. Different phytochemicals were also detected in all of the coffee extracts. Roasted coffee extracts and instant coffees exhibited free-radical scavenging properties in a dose-dependent manner, for which drip coffee was observed to be the most effective (p < 0.05). All coffee extracts, instant coffee varieties and CGA could effectively bind ferric ion in a concentration-dependent manner resulting in an iron-bound complex. Roasted coffee extracts were neither toxic to normal mononuclear cells nor breast cancer cells. The findings indicate that phenolics, particularly CGA, could effectively contribute to the iron-chelating and free-radical scavenging properties observed in coffee brews. Thus, coffee may possess high pharmacological value and could be utilized as a health beverage.

Free radical scavenging properties and phenolic characterization of some edible plants

2009 ◽  
Vol 114 (1) ◽  
pp. 276-281 ◽  
Author(s):  
Ilkay Orhan ◽  
Murat Kartal ◽  
Mahmoud Abu-Asaker ◽  
F. Sezer Şenol ◽  
Gülderen Yilmaz ◽  
...  
Keyword(s):  
Free Radical ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Edible Plants ◽  
Radical Scavenging Properties

Antihypertensive and free radical scavenging properties of enzymatic rapeseed protein hydrolysates

2013 ◽  
Vol 141 (1) ◽  
pp. 153-159 ◽  
Author(s):  
Rong He ◽  
Adeola Alashi ◽  
Sunday A. Malomo ◽  
Abraham T. Girgih ◽  
Dongfang Chao ◽  
...  
Keyword(s):  
Free Radical ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Protein Hydrolysates ◽  
Rapeseed Protein ◽  
Rapeseed Protein Hydrolysates ◽  
Radical Scavenging Properties

scholarly journals EVALUATION OF ANTIOXIDANT AND FREE RADICAL SCAVENGING ACTIVITIES OF DIFFERENT SOLVENT EXTRACTS OF LEAVES OF PIPER UMBELLATUM

2017 ◽  
Vol 10 (2) ◽  
pp. 274
Author(s):  
Sethupandian Geetha ◽  
Kokkaiah Irulandi ◽  
Palanichamy Mehalingam
Keyword(s):  
Antioxidant Activity ◽  
Free Radical ◽  
Ethyl Acetate ◽  
Methanol Extract ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Free Radical Scavenging ◽  
Frap Assay ◽  
Radical Scavenging Properties

Objective: This study was designed to determine the Total phenol, flavonoid content, antioxidant and free radical scavenging properties of different solvent extracts of Piper umbellatum.  Methods: Different solvent extracts evaluated with DPPH radical scavenging activity and Reducing power activity.Results: The presence of phenol and flavonoid showed highly in the methanol extracts than ethyl acetate and acetone extracts. All the extracts have various level of antioxidant activity. Methanol solvent extract have good extraction and show significant antioxidant activity. The effect of reducing power of methanol extract revealed good antioxidant activity compare with other tested extracts.Conclusion: On the basis of the above results we concluded that methanol extract of Piper umbellatum whole plant extracts shows significant antioxidant activity than ethyl acetate and acetone extracts.Keywords: Piper umbellatum, Antioxidant, DPPH, FRAP assay, Polar, Non polar solvents

Synthesis, Characterization and Free Radical Scavenging Properties of Rosmarinic Acid Fatty Esters

2010 ◽  
Vol 87 (6) ◽  
pp. 615-620 ◽  
Author(s):  
Jérôme Lecomte ◽  
Luis Javier López Giraldo ◽  
Mickaël Laguerre ◽  
Bruno Baréa ◽  
Pierre Villeneuve
Keyword(s):  
Free Radical ◽  
Rosmarinic Acid ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Fatty Esters ◽  
Radical Scavenging Properties
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