scholarly journals Health Effects of Grape Seed and Skin Extracts and Their Influence on Biochemical Markers

Molecules ◽  
2020 ◽  
Vol 25 (22) ◽  
pp. 5311
Author(s):  
Lenka Sochorova ◽  
Bozena Prusova ◽  
Martina Cebova ◽  
Tunde Jurikova ◽  
Jiri Mlcek ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Biochemical Markers ◽  
Neuroprotective Effect ◽  
Grape Seed ◽  
Seed Extract ◽  
Vitis Vinifera L ◽  
Skin Extract ◽  
High Biological Activity ◽  
High Concentrations ◽  
Health Complications

This review is focused on the study of the effects of grape seed and skin extract (GSSE) on human health. GSSE contains high concentrations of important polyphenolic substances with high biological activity. This review is a summary of studies that investigate the effects of GSSE on diabetes mellitus, cardiovascular disease and cancer, its neuroprotective effect, and its effects on the gastrointestinal tract and other health complications related to these diseases. The results of the studies confirm that the anti-inflammatory, antiapoptotic, and pro-proliferative effects of “Vitis vinifera L.” seed extract reduce the level of oxidative stress and improve the overall lipid metabolism.

Neuroprotective effect of grape seed and skin extract on lithium-induced oxidative stress in healthy rat brain

2017 ◽  
Vol 11 (1) ◽  
pp. 85-94 ◽  
Author(s):  
Ali Mezni ◽  
Hanène Aoua ◽  
Ferid Limam ◽  
Ezzedine Aouani
Keyword(s):  
Oxidative Stress ◽  
Rat Brain ◽  
Neuroprotective Effect ◽  
Grape Seed ◽  
Skin Extract

scholarly journals Application of Advanced Drying Technologies for Obtaining Bioactive Beer Yeast and Grape Seed Extract Powders

1970 ◽  
Vol 66 (2) ◽  
Author(s):  
Alina NICULA ◽  
Alexandru. T. NICULA ◽  
Carmen SOCACIU ◽  
Pierre DuBREUCQ
Keyword(s):  
Bioactive Compound ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Seed Extract ◽  
Outlet Temperature ◽  
Drying Process ◽  
Fluid Bed ◽  
High Concentrations ◽  
Beer Yeast

As the food industry is interested to recuperate the valuable waste such as beer yeast (Saccharomyces cervisiae) and grape seed (Vitis vinifera), both with high nutritional and health promotion effects, new products and processes are expected to be released on the market. The new modern drying technologies used to process natural compounds and extracts aim a protected evaporation under controlled temperatures and immobilization on matrices, in order to keep high concentrations of bioactive compound in the final products. One of the most important technological parameter during the drying process is the Inlet and Outlet Temperature Using Spray Drying (SD) and Fluid Bed Drying (FBD) optimized technologies we obtained beer yeast (BY) and the grape seed extract (GSE) solid forms, demonstrating that functionality is well preserved (by determination of vitamins B and phenolics, respectively) in the final products comparing with the initial, genuine extracts. Beer yeast and grape seed concentrated forms (stabilized powders and granulated formulas) have emerging consequences in this context and attract the modern consumer for their positive action on health.

scholarly journals Noise Exposure Decreases the Number of Spermatozoa in Male Mice (Mus musculus L.) Even With Grape Seed Extract (Vitis vinifera L.) Administration

2020 ◽  
Vol 5 (2) ◽  
pp. 70-75
Author(s):  
Ghestiara Siregar
Keyword(s):  
Treatment Group ◽  
Mus Musculus ◽  
Noise Exposure ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Seed Extract ◽  
Control Group ◽  
Vitis Vinifera L ◽  
Not Given ◽  
Male Mice

  Excessive continuous noises exposure changes the male hormone system which leads to formation of oxidative stress and results in disrupt of semen quality. This condition can be reduced by the use of antioxidants. Grape seed is one of the antioxidants that contains phenol components that have Resveratrol compounds. This research aimed to observe the effect of noise exposure on the number of spermatozoa of male mice given grape seed extract. The method of the research was a post-test only control group design with research subjects of 30 male Mus musculus L. (Swiss Webster) mice divided into 5 groups: group A (treatment control) was not given noise exposure and grape seed extract, group B (negative control) was not given noise exposure and was given grape seed extract, groups C, D, E (treatment group) were given noise exposure with sequential intensities of 65 dB, 85 dB, 105 dB. The treatment was given for 33 days. The results showed that noise exposure with different intensities of 65 dB, 85 dB, 105 dB reduced the spermatozoa count of male Swiss Webster mice even with the administration of grape seed extract. One Way Anova test was used to analyze the data with p-value of 0.001. Conclusion: There were differences in spermatozoa count between the control group and the treatment group. Provision of noise exposure with a value above the threshold limit reduces the number of male Swiss Webster mice spermatozoa given with grape seed extract. Keywords: Number of Spermatozoa, Grape Seed Extract, Noise exposure  

scholarly journals Protective effect of grape seed and skin extract on high dosage garlic-induced renal oxidative stress

2012 ◽  
Vol 7 (2) ◽  
Author(s):  
Sonia Hamlaoui ◽  
Oumayma Samti ◽  
Meherzia Mokni ◽  
Nadia Limam ◽  
Alice Carrier ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Protective Effect ◽  
Grape Seed ◽  
Skin Extract

Grape seed and skin extract alleviates high-fat diet-induced renal lipotoxicity and prevents copper depletion in rat

2013 ◽  
Vol 38 (3) ◽  
pp. 259-267 ◽  
Author(s):  
Kamel Charradi ◽  
Salem Elkahoui ◽  
Ines Karkouch ◽  
Ferid Limam ◽  
Ghaith Hamdaoui ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
High Fat Diet ◽  
Public Health Problem ◽  
Grape Seed ◽  
Standard Diet ◽  
Skin Extract ◽  
High Fat ◽  
Oxidative Stress Status ◽  
Almost All ◽  
Copper Depletion

Obesity is a public health problem that contributes to morbidity and mortality from diabetes, heart disease, stroke, and cancers. The purpose of this investigation was to analyse the link between obesity-induced oxidative stress, renal steatosis, and kidney dysfunction, as well as the protective effect of grape seed and skin extract. Rats were fed a standard diet or a high-fat diet for 6 weeks and were either treated or not treated with grape seed and skin extract. Fat-induced oxidative stress was evaluated in the kidney with a special emphasis on transition metals. High-fat diet induced triglyceride deposition and disturbances in kidney function parameters, which are linked to an oxidative stress status and depletion of copper from the kidney. Grape seed and skin extract abrogated almost all fat-induced kidney disturbances. Grape seed and skin extract exerted potential protection against fat-induced kidney lipotoxicity and should find potential application in other kidney-related diseases.

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