scholarly journals Ferulago nodosa Subsp. geniculata (Guss.) Troia & Raimondo from Sicily (Italy): Isolation of Essential Oil and Evaluation of Its Bioactivity

Molecules ◽  
2020 ◽  
Vol 25 (14) ◽  
pp. 3249 ◽  
Author(s):  
Natale Badalamenti ◽  
Vincenzo Ilardi ◽  
Sergio Rosselli ◽  
Maurizio Bruno ◽  
Filippo Maggi ◽  
...  

Ferulago nodosa (L.) Boiss. (Apiaceae) is a species occurring in the Balkan-Tyrrhenian area. The object of the present study is Sicilian F. nodosa subsp. geniculata (Guss.) Troia & Raimondo, classified as an endemic F. nodosa subspecies. Aerial parts of this plant species were subjected to hydrodistillation to obtain an essential oil. A total of 93 compounds were identified with 2,3,6-trimethyl benzaldehyde (19.0%), spathulenol (9.0%), (E)-caryophyllene (5.4%), and caryophyllene oxide (5.4%) as the main components. The biological activities of F. nodosa essential oil were also investigated. This oil showed an interesting antioxidant potential in a 2,2′-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) test (IC50 of 14.05 μg/mL). Additionally, hypoglycemic and antilipidemic effects were evaluated. Lipase enzyme was inhibited with an IC50 value of 41.99 μg/mL. Obtained data demonstrated that F. nodosa could be considered a promising source of bioactive compounds useful for the treatment and management of obesity.

Agronomy ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 399 ◽  
Author(s):  
Abdulaziz Assaeed ◽  
Abdelsamed Elshamy ◽  
Abd El-Nasser El Gendy ◽  
Basharat Dar ◽  
Saud Al-Rowaily ◽  
...  

Pulicaria genus (fleabane) is characterized by its fragrant odor due to the presence of essential oil (EO). According to the literature reviews, the EO of Pulicaria somalensis O.Hoffm. (Shie) is still unexplored. For the first time, 71 compounds were characterized in EO derived from above-ground parts of P. somalensis collected from Saudi Arabia. Sesquiterpenes represented the main components (91.8%), along with minor amounts of mono-, diterpenes, and hydrocarbons. Juniper camphor (24.7%), α-sinensal (7.7%), 6-epi-shyobunol (6.6%), α-zingiberene (5.8%), α-bisabolol (5.3%), and T-muurolol (4.7%) were characterized as main constituents. The correlation analysis between different Pulicaria species showed that P. somalensis has a specific chemical pattern of the EO, thereby no correlation was observed with other reported Pulicaria species. The EO showed significant allelopathic activity against the weeds of Dactyloctenium aegyptium (L.) Willd. (crowfoot grass) and Bidens pilosa L. (hairy beggarticks). The IC50 value on the germination of D. aegyptium was double that of B. pilosa. The IC50 values on the root growth of B. pilosa and D. aegyptium were 0.6 mg mL−1 each, while the shoot growths were 1.0 and 0.7 mg mL−1, respectively. This variation in the activity could be attributed to the genetic characteristics of the weeds. Moreover, the EO exhibited significant antioxidant effects compared to ascorbic acid. Further studies are necessary to verify if these biological activities of the EO could be attributable to its major compounds.


2016 ◽  
Vol 71 (11-12) ◽  
pp. 403-408 ◽  
Author(s):  
Mohaddese Mahboubi ◽  
Elaheh Mahdizadeh ◽  
Rezvan Heidary Tabar

Abstract The purpose of our study was to compare the chemical compositions and antimicrobial and antioxidant activities of Pycnocycla spinosa and Pycnocycla flabellifolia essential oils. cis-Asarone (62.5%) and widdra-2,4(14)-diene (9%) were the main components of P. spinosa aerial part essential oil, while elemicin (60.1%) and caryophyllene oxide (9.8%) were the main components of P. spinosa seed essential oil. α-Phellandrene (25.5%), p-cymene (15.3%), and limonene (13.3%) were found in P. flabellifolia essential oil. The inhibition zone diameters for P. flabellifolia essential oil were significantly higher than for the two other essential oils from P. spinosa (p<0.05). In broth dilution assay (µL/mL), the sensitive microorganism to Pycnocycla sp. (P. spinosa, P. flabellifolia) was Aspergillus niger, followed by Candida albicans. In 2,2-diphenyl-1-picrylhydrazyl (DPPH) system, P. spinosa aerial parts essential oil (IC50=548 µg/mL) had higher antioxidant activity than that of two other essential oils.


2013 ◽  
Vol 8 (1) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
Emilia Mancini ◽  
Laura De Martino ◽  
Hanna Malova ◽  
Vincenzo De Feo

The chemical composition of the essential oil from aerial parts of Calamintha nepeta (L.) Savi, collected in the Campania Region, was obtained by hydrodistillation and analyzed by GC and GC-MS. In all, 42 compounds were identified. The oil was characterized by a prevalence of the sesquiterpenic fraction (80.8%). The main components were 1,10-di- epi-cubenol (18.5%), allo-aromadendrene epoxide (11.4%) and cadalene (5.7%). The essential oil was evaluated for its in vitro potential phytotoxic activity against germination and initial radical growth of Raphanus sativus L., Lepidium sativum L., Sinapis arvensis L., Triticum durum L. and Phalaris canariensis L. seeds. The essential oil showed no antioxidant activity.


Foods ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 1784
Author(s):  
Yuanpeng Hao ◽  
Jiamu Kang ◽  
Xiaoqi Guo ◽  
Rui Yang ◽  
Yuliang Chen ◽  
...  

Fennel and dill are widely used as food additives owing to their various biological activities, such as antioxidants, antimicrobials, food-preservatives, and seasoning capacities. Herein, the nutritional composition and essential oil (EO) chemical profiles of fruits, umbels, stalks, and roots from one dill and two fennel cultivars were evaluated. The fruits had the highest content of crude protein (≥ 15%), crude fat (≥ 8%), and phosphorus (≥ 0.5%), and exhibited the highest total energy (≥ 20 MJ/kg) and EO yield (≥ 2%). Moreover, estragole (86.56% in Fdf), anethole (71.17% in Fhf), fenchone (16.74% in Fhf), limonene (50.19% in Agf), and carvone (42.41% in Agf) were the main components of the EOs generated from the fruits. The chemical profiles of EOs in the roots were significantly different from those of the aerial parts of the fennel and dill; thus, the roots and aerial parts could be distinguished based on myristicin (Variable Importance in Projection (VIP) = 1.90399) and apiol (VIP = 1.85922). The EO components of the aerial parts varied remarkably, and the chemical markers for differentiating these three cultivars were anethole (VIP = 1.36571), estragole (VIP = 1.30292), and carvone (VIP = 1.11947). Overall, our results provide a noteworthy chemical basis for further development of fennel and dill, especially as food additives.


2011 ◽  
Vol 6 (1) ◽  
pp. 1934578X1100600 ◽  
Author(s):  
Nabila Bouderdara ◽  
Abdelhakim Elomri ◽  
Lakhdar Djarri ◽  
Kamel Medjroubi ◽  
Elisabeth Seguin ◽  
...  

The essential oil of aerial parts of Cachrys libanotis L. (Apiaceae) from east Algeria was extracted by hydrodistillation and analyzed by GC-FID and GC-MS. Thirty-one compounds were identified, the main components being germacrene-D (18.0%), γ-terpinene (6.4%), p-cymene (5.5%), caryophyllene oxide (5.1%), and limonene (5.1%).


Molecules ◽  
2019 ◽  
Vol 24 (1) ◽  
pp. 204 ◽  
Author(s):  
Charaf Eddine Watheq Malti ◽  
Clémentine Baccati ◽  
Magali Mariani ◽  
Faiçal Hassani ◽  
Brahim Babali ◽  
...  

The chemical composition of 18 oil samples of Santolina africana isolated from aerial parts at full flowering, collected in three locations in eastern Algeria was determined by GC(RI), GC/MS and 13C-NMR analysis. The major components were: germacrene D, myrcene, spathulenol, α-bisabolol, β-pinene, 1,8-cineole, cis-chrysanthenol, capillene, santolina alcohol, camphor, terpinen-4-ol and lyratol. The chemical composition appeared homogeneous and characterized by the occurrence of four derivatives which exhibited a conjugated alkene dialkyne moiety. They were identified for the first time in an essential oil from S. africana. The collective oil sample exhibited moderate antimicrobial and antioxidant activities whereas the anti-inflammatory activity presented a real potential. IC50 value of Santolina africana essential oil (0.065 ± 0.004 mg/mL) is 5-fold higher than IC50 value of NDGA used as positive control.


2014 ◽  
Vol 9 (11) ◽  
pp. 1934578X1400901 ◽  
Author(s):  
Simona Casiglia ◽  
Maurizio Bruno ◽  
Felice Senatore

The chemical composition of the essential oil from aerial parts of L. nepetaefolia (L.) R. Br. collected in Nicaragua was evaluated by GC and GC-MS. The main components were ( Z)-phytol (22.8%), caryophyllene oxide (18.9%) and hexahydrofarnesylacetone (9.0%). The antibacterial activity against several Gram + and Gram - bacteria, including Bacillus cereus and B. subtilis, both infesting historical cellulosic material, was also determined. B. cereus, B. subtilis and Staphylococcus epidermis were the most affected by the action of the oil.


2014 ◽  
Vol 9 (9) ◽  
pp. 1934578X1400900
Author(s):  
Antonella Maggio ◽  
Luana Riccobono ◽  
Svetlana Bancheva ◽  
Maurizio Bruno ◽  
Felice Senatore

In the present study the chemical compositions of the essential oils from aerial parts of Centaurea davidovii Urum. and C. parilica Stoj. & Stef., both endemic to Bulgaria, were evaluated by GC and GC-MS. The main components of C. davidovii were β-eudesmol (13.9%), spathulenol (13.3%), caryophyllene oxide (10.1%) and ( Z)-phytol (5.4%). The main components of C parilica were hexadecanoic acid (39.2%), ( Z, Z)-9,12-octadecadienoic acid (11.9%), caryophyllene oxide (6.8%) and spathulenol (6.6%). In order to compare the essential oils composition of these taxa and of related species a PCA analysis was carried out.


2021 ◽  
Vol 10 (8) ◽  
pp. e37410817440
Author(s):  
Antonia Tavares Barbosa ◽  
Vitor Hugo Neves da Silva ◽  
Bruna Yuka Koide da Silva ◽  
Aniele da Silva Neves Lopes ◽  
Isabel Reis Guesdon ◽  
...  

The Vismia Vand. genus encompasses many species indigenous to the Amazon rain forest where they are popularly known as “Lacre” bark and leaves are widely employed by locals to treat dermatophytoses. The aim of this study was to investigate the chemical composition of essential oils (EOs) extracted from the aerial parts of the species Vismia guianensis (Aubl.) Choisy and Vismia cayennensis (Jacq.) Pers. and to assess their antimicrobial activity against the bacteria Staphylococcus aureus Rosenbach 1884 and Escherichia coli (Migula 1895) Castellani and Chalmers 1919 as well as the fungi Candida albicans (C.P. Robin) Berkhout 1923 and Candida parapsilosis (Ashford) Langeron & Talice 1932. The analysis of the chemical composition of the essential oil extracted from V. guianensis leaves (EOVg) indicated 46 components, of which three sesquiterpenes predominated, namely: (E)-caryophyllene (10.40%), α-copaene (29.45%), and (E)-nerolidol (24.06%). As to the essential oil from V. cayennensis leaves (EOVc), 61 components were identified, of which two oxygenated sesquiterpenes stood out as the main components, namely, germacrone (25.42%) and curzerene (25.29%). EOVg exhibited Minimum Inhibitory Concentration (MIC) of 1.56 µg/mL against the yeast C. parapsilosis whereas EOVc was active against the bacteria E. coli and S. aureus as well as the yeast C. parapsilosis. The results obtained in this study strongly recommend further research on the essential oils in question with a view to isolating and identifying the components responsible for their observed antimicrobial activities.


Molecules ◽  
2020 ◽  
Vol 25 (3) ◽  
pp. 595 ◽  
Author(s):  
Daniela Gruľová ◽  
Lucia Caputo ◽  
Hazem S. Elshafie ◽  
Beáta Baranová ◽  
Laura De Martino ◽  
...  

Searching for new bio-based herbicides is crucial for decreasing chemical pollution, protecting the environment, and sustaining biodiversity. Origanum vulgare is considered a promising source of essential oil with herbicidal effect. The mode of action is not known. The present study focused on (1) comparison of phytotoxic activity of Origanum vulgare EO on monocot (Triticum aestivum and Hordeum vulgare) and dicot species (Lepidium sativum and Sinapis alba); (2) and evaluating other antimicrobial biological activities against phytopatogen bacteria (Clavibacter michiganensis, Pseudomonas syringae pv. phaseolicola, Pseudomonas savastanoi, and Xanthomonas campestris); antifungal activity against Monilinia fructicola, Aspergillus niger, Penicillium expansum, and Botrytis cinerea; cytotoxic activity and antioxidant activity. According to the GC/MS analyses, the EO belongs to the thymol chemotype O. vulgare with its high content of thymol (76%). Germination of all four species was not influenced by EO. The phytotoxic effect was statistically significant in the monocot species, while in the dicot species the opposite was observed—a stimulation effect, which was also statistically significant. Strong biological activity of O. vulgare EO was noted on all phytopatogen bacteria and fungi in the highest dose. Cytotoxic activity showed an IC50 = 50.5 μg/mL. Antioxidant activity showed an IC50 = 106.6 μg/mL after 45 min experimental time. Based on the presented results, it is possible to conclude that thymol chemotype O. vulgare essential oil could be potentially used as a herbicide with selective effects on monocot plant species.


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