scholarly journals Microfluidics in Haemostasis: A Review

Molecules ◽  
2020 ◽  
Vol 25 (4) ◽  
pp. 833 ◽  
Author(s):  
Heta Jigar Panchal ◽  
Nigel J Kent ◽  
Andrew J S Knox ◽  
Leanne F Harris

Haemostatic disorders are both complex and costly in relation to both their treatment and subsequent management. As leading causes of mortality worldwide, there is an ever-increasing drive to improve the diagnosis and prevention of haemostatic disorders. The field of microfluidic and Lab on a Chip (LOC) technologies is rapidly advancing and the important role of miniaturised diagnostics is becoming more evident in the healthcare system, with particular importance in near patient testing (NPT) and point of care (POC) settings. Microfluidic technologies present innovative solutions to diagnostic and clinical challenges which have the knock-on effect of improving health care and quality of life. In this review, both advanced microfluidic devices (R&D) and commercially available devices for the diagnosis and monitoring of haemostasis-related disorders and antithrombotic therapies, respectively, are discussed. Innovative design specifications, fabrication techniques, and modes of detection in addition to the materials used in developing micro-channels are reviewed in the context of application to the field of haemostasis.

2010 ◽  
Vol 34 (1) ◽  
pp. 41 ◽  
Author(s):  
Diane Deshong ◽  
Amanda Henderson

With increasing pressures on the skilled nursing workforce, strategies need to be developed to maximise the value of the existing workforce without impacting on the quality of care delivery. This paper reports on the introduction of a Commonwealth and State subsidised program for assistants-in-nursing (AINs) to assist in addressing the global nursing shortage. The program – which has included education sessions with registered nurses about the role of the AIN, delegation and supervision, and has also sustained support to the participants throughout the duration of their employment – has delivered benefits locally to the Princess Alexandra Hospital (PAH) and, broadly, to the nursing profession. Most of the participants completing the program have chosen to continue their employment at PAH or pursue further studies in nursing. What is known about the topic?The shortage of skilled nurses means there is a need for innovative solutions to support the existing workforce. What does this paper add?The development of an assistant-in-nursing role was seen as a successful development for a Queensland hospital. What are the implications for practitioners?The trained assistants have largely remained employed in the area and 68% have gone on to further nursing education.


Author(s):  
Ferruccio Ceriotti

Abstract The classical role of the clinical laboratory, seen as the central place where the samples converge and from where the results are distributed, will be challenged by the development of digital health, the application of information technology (big data) and genomics to health care. When the development of disruptive new technologies will allow the production of accurate results outside the laboratory, its role will dramatically change. However, several factors are slowing down these evolutions. The quality of the existing data is relatively poor: lack of standardization of results, different units, different reference intervals, etc. The lab-on-a-chip technology is still relatively far from broad range application and the costs are higher than the traditional methods. There is the need for regulations of direct to consumer approaches that are posing big ethical problems. In the future, the clinical laboratory will maintain part of the “classical” role in the areas of research education and services. The large production will continue, favored by consolidation and reduction of the number of laboratories. The specialists of laboratory medicine have the task of collaborating with the national scientific societies and with the industry for improving harmonization of all the production phases, thus allowing the production of meaningful big data. Clinical laboratories have the role of implementing translational medicine. The new point-of-care (POC) technologies still need validation, the clinical laboratory is the place to do it. The advisory role toward clinicians and patients has to be improved, and a role in validating laboratory data interpretation apps and in controlling and supervising the functionality and the quality of the POC devices has to be developed.


Author(s):  
Awab Elsayed ◽  
Mohammed Elamin

This review article aims to deliver a full and comprehensive understanding of the different types of coils including their limitations and methods of improvement. The efficient design of coils has a significant impact on enhancing the quality of the poor formability alloys. This study further discusses the role of the most important parameters that play a vital role in coils design. The scope of this review includes the modern design of coils that are used in several industries alongside their most suitable applications and end products. Moreover, based on the findings of some important studies in the literature, a detailed review on the numerous methods to evaluate coils performance and how to improve coils quality is provided.


Author(s):  
O. Oleshko ◽  
◽  
Yu. Petrovska ◽  

This study sheds light on the concept of phytodesign and its tasks, outlines its main functions, as well as the role of landscape design in the formation of the subject environment. The modern trends in landscaping of urban areas, the main directions and means of landscaping are revealed, in particular the function of plants in the city environment. In view of the increasing population density, the increase in the number of vehicles, there is a constant search for innovative solutions in the organization of urban greening. Phytodesign has long gone beyond the premises and is actively penetrating the streets of the city, complementing small architectural forms, street furniture, fences and elements of city infrastructure. The role of landscaping, as a systemof conservation, extension and improvement of plantations in cities and villages, is becoming increasingly important, especially in the area of sanitation. Specialists of various profiles work in this direction: ecologists, botanists, chemists, physicians, landscape designers, agronomists and many others, offering innovative solutions for technologies of both plant cultivation and space management. In view of the increasing population density, the increase in the number of vehicles, there is a constant search for innovative solutions in the organization of urban greening. The work of a modern designer with plants in general is manifested in several directions: landscape design, green construction, phytodesign. If landscape design and green construction are large-scaled and sometimes dominate the formation of the spatial environment of a city or a separate local area,then the phytodesign is less extensive and complements the elements of the spatial environment. Today, researchers are increasingly focusing onthe aesthetic properties of phytodesign. It becomes an element of the general concept of creating a new natural and anthropogenic environment with the most comfortable living conditions; energy source for bioclimatization and greening of indoor and outdoor environments.An important factor affecting the mental comfort of the urban resident is the level of quality of the environment -a sufficient level of landscaping a favorable ecological state, maintaining human connection with nature. As a result of urbanization, human beings have become contaminated in the local environment, therefore urgent measures are needed to restore the quality of the air environment based on the natural mechanisms of ecological metabolism involving plants. Vegetation as an environment –the restorative system provides and regulates the composition of the air, the degree of its pollution, the climatic characteristics of the territories, reduces the influence of the noise factor and is a source of aesthetic recreation, which in turnensures the comfort of living in the city. Landscaping aims to increase the flow of oxygen and reduce the level of pollution of the atmosphere of the city, in addition, landscaping affects the formation of aesthetic appearance of the environment. The workof a modern designer with plants in general is manifested in several directions: landscape design, green construction, phytodesign. If landscape design and green construction are large-scaled and sometimes dominate the formation of the spatial environmentof a city or a separate local area, then the phytodesign is less extensive and complements the elements of the spatial environment. Once phytodesign was exclusively for the interior, nowadays its active appearance in the urban environment is absolutely normal in both public spaces and in addition to small architectural forms, street furniture, fences, infrastructure and protective structures.


Author(s):  
I Gusti Ayu Putu Sukmarani

Cosmetics are a preparation or product for women and men that are used on the outside of the human body. The cosmetic industry implements an operational system in producing cosmetics by ensuring the quality and safety of cosmetic products to be produced. A cosmetic industry in producing cosmetics must comply with the standard requirements for the quality of cosmetic products that have been determined in accordance with the CPKB (Good C Manufacturing Practices). CPKB is a basic feasibility guideline according to the requirements aimed at making a cosmetic industry produce safe, useful and quality products. Pharmacists who work as QA (Quality Assurance) in the pharmaceutical industry for quality assurance of cosmetic products. The benefit of this article is the role of pharmacists in quality assurance of cosmetic products according to GCMP provisions in the cosmetic pharmaceutical industry. The purpose of this article is to determine the role of pharmacists in the quality assurance of cosmetic products contained in the GCMP. The method in this article is literature study using sources, guidelines, references regarding the main duties and functions of a pharmacist. Quality Assurance (QA) functions to ensure that product quality remains during the shelf-life to distribution processes, ensures that self-inspection or quality audits are in accordance with procedures, ensures suppliers of the starting materials used and the packaging are evaluated in accordance with the provisions in order to meet quality requirements. The task of pharmacists as quality assurance is to regulate the design, manufacture and development of products in accordance with applicable regulations, implement the product manufacturing process to comply with the provisions, ensure that the supply of materials, use of starting materials, manufacture and packaging are correct.  


2011 ◽  
Vol 135 (11) ◽  
pp. 1405-1414 ◽  
Author(s):  
Kent Lewandrowski ◽  
Kimberly Gregory ◽  
Donna Macmillan

Context.—Managing the quality of point-of-care testing (POCT) is a continuing challenge. Advances in testing technologies and the development of specialized informatics for POCT have greatly improved the ability of hospitals to manage their POCT program. Objectives.—To present the evolving role of technology improvement, informatics, and program management as the key developments to ensure the quality of POCT. Data Sources.—This presentation is based on a review of the literature and on our experiences with POCT at the Massachusetts General Hospital (Boston). Conclusions.—Federal and state regulations, along with accreditation standards developed by the College of American Pathologists and The Joint Commission, have established guidelines for the performance of POCT and have provided a strong incentive to improve the quality of testing. Many instruments for POCT have incorporated advanced design features to prevent analytic and operator errors. This, along with the development of connectivity standards and specialized data management software, has enabled remote review of test data and electronic flow of information to hospital information systems. However, documentation of manually performed, visually read tests remains problematic and some POCT devices do not have adequate safeguards to prevent significant errors. In the past 2 decades the structure of a successful POCT management program has been defined, emphasizing the role of POCT managers working in conjunction with a pathology-based medical director. The critical skill set of POCT managers has also been identified. The POCT manager is now recognized as a true specialist in laboratory medicine.


Author(s):  
Muhammad A. Javed ◽  
Muhammad Afzal ◽  
Shazia Sajid ◽  
Amjad Ali ◽  
Muhammad E. Safdar ◽  
...  

This study aimed at assessing the role of water users’ associations (WUAs) in conflicts resolution among water users. A sample of 100 executive members of WUAs was selected purposefully from twenty randomly selected registered and improved watercourses. The data was collected through a detailed, validated and pre-tested interview schedule and analysed through SPSS. Findings showed that social conflicts (x̄=2.00), repair and maintenances of watercourse (x̄=1.91) and disputes on watercourse design, route and section to be lined (x̄=1.81) were the top most causes of conflicts among the water users. Uprooting of trees (86.0%), payment of farmers’ share (79.0%), quality of materials used (73.0%), section of watercourses to be lined (71.0%), working of farmers’ labor (70.0%) and provision of labour (69.0%) were the important reasons for differences among water users. Satisfaction level of water users regarding contribution of WUAs in conflict resolution (x̄=3.98) was lying between medium to high tending towards high while, effectiveness of WUAs in conflict resolution (x̄=4.17) was lying between high and very high tending towards very high. There exist a stronger association between the role of WUAs as dependent and strategy to resolve the conflicts as independent variables while, the role of WUAs was strongly dependent on their response to the complaints and it was also dependent on determining the causes of these conflicts. Thus, WUAs must be promoted at every level for enhancing their role for conflicts resolution through regular trainings to improve their conflicts resolution abilities on modern lines and must be made more powerful in terms of authority to decide common conflicts at the spot.


2021 ◽  
Vol 3 (1) ◽  
pp. 60-66
Author(s):  
Ewa Parkita

The purpose of this article is to present various solutions concerning music education aided by computer technologies. The article applies public music education. The author attempts to provide an answer to questions concerning the role of music teachers working with new media , which requires them to constantly improve and expand their skills. How are they able to utilise new technological achievements while at the same time blending them with well-proven, traditional methods of music teaching/learning, without falling prey to the dangers of modern media ? Any attempts at using innovative solutions are bound to cause numerous challenges for students, teachers, and the entire education system. However, the effects of such actions could contribute to the improvement of the quality of music education in society, which justifies the efforts. The intention of the author is attempt to look into the future on the basis of the existing data sources, analyses and global pedagogical trends and to search for theoretical and practical solutions, which may influence the formulation of the paradigms in modern music teaching.


2020 ◽  
Author(s):  
Olga Florea ◽  
Jean Charles Dufour ◽  
Chloe Magnin ◽  
Philippe Brouqui ◽  
Sophia Boudjema

ABSTRACTBackgroundAdverse events are serious and frequent complications most often linked to the quality of nursing care.PurposeWe evaluated the compliance to traceability of nursing care at bedside using the Patient Smart Reader®, a personal digital assistant with a barcode.MethodsWe compared paper record forms, specific computer software in the hospital information system and the Patient Smart Reader®.ResultsThe Patient Smart Reader enhanced the recording of 90% of nursing care surveyed. Regarding the insertion of blood catheters, compliance rates increased from 44.19 % to 100%, and blood catheter monitoring has risen from 29.64% to 80.74%. Urinary catheter monitoring and insertion recording increased from 10.23% to 55.43% and from 16.67% to 100 % respectively.ConclusionsProviding to caregivers a nursing record system using barcoded implements at the point of care in real time significantly improved traceability of the nursing care.


2017 ◽  
Vol 3 (2) ◽  
pp. 140 ◽  
Author(s):  
Radek Pudil ◽  

Cardiovascular (CV) disease and cancer remain the two most common causes of mortality in developed countries; however, progress in the treatment of malignant diseases significantly improved survival of oncological patients. Similarly, there is an increased number of the patients with malignancy who have a history of CV disease or an increased CV risk. Rates of CV problems from cancer-related therapeutics are high, and cardiotoxicity is the second most common cause of morbidity and mortality in cancer survivors. Therefore, there is a need for the development of an efficient programme to manage the problem of cardiotoxicity with the aim to decrease morbidity and mortality in patients and to improve their quality of life. For this purpose, cardio-oncological clinics should be an essential part of the strategy.


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