scholarly journals Optical Resolution of Rimantadine

Molecules ◽  
2019 ◽  
Vol 24 (9) ◽  
pp. 1828 ◽  
Author(s):  
Jianlin Han ◽  
Ryosuke Takeda ◽  
Tatsunori Sato ◽  
Hiroki Moriwaki ◽  
Hidenori Abe ◽  
...  
Keyword(s):  
Low Cost ◽  
Optical Resolution ◽  
Cost Structure ◽  
Enantiomerically Pure ◽  
Rimantadine Hydrochloride ◽  
Synthetic Studies

This work discloses a new procedure for the resolution of commercially available racemic rimantadine hydrochloride to enantiomerically pure (S)-rimantadine using (R)-phenoxypropionic acid as a recyclable resolving reagent. Good chemical yields, operational ease, and low-cost structure underscore the preparative value of this method for the production of enantiomerically pure rimantadine for medicinal or synthetic studies.

Synthetic studies on the key component of the new generation of quinolonecarboxylic acid, DU-6859. 1. Synthesis of (1R,2S)-2-fluorocyclopropylamine by the use of optical resolution

Tetrahedron ◽  
1994 ◽  
Vol 50 (13) ◽  
pp. 3889-3904 ◽  
Author(s):  
Osamu Tamura ◽  
Masaru Hashimoto ◽  
Yuko Kobayashi ◽  
Tadashi Katoh ◽  
Kazuhiko Nakatani ◽  
...  
Keyword(s):  
Optical Resolution ◽  
Synthetic Studies ◽  
New Generation

Small Footbridges: 2 Contexts, 2 Responses

2021 ◽  
Author(s):  
Vincent Servais ◽  
Christophe Peigneux
Keyword(s):  
Reinforced Concrete ◽  
High Performance ◽  
Low Cost ◽  
Cost Structure ◽  
Urban Site ◽  
Weathering Steel ◽  
Fibre Reinforced Concrete ◽  
Design Technique ◽  
High Performance Fibre ◽  
Minimalist Conception

<p>This paper presents the design of two small footbridges in two different sites and economical contexts. The first footbridge, located in an urban site, is an arch made of Ultra-High-Performance Fibre-Reinforced Concrete (UHPFRC). The design technique combines the use of a contemporary material with the reappropriation of ancestral methods. The second footbridge, located in a remarkable natural site and made of weathering steel, presents both a tie-arch and truss structure. This minimalist conception leads to a “low- cost” structure.</p>

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