scholarly journals Recent Advances in the Addition of Amide/Sulfonamide Bonds to Alkynes

Molecules ◽  
2019 ◽  
Vol 24 (1) ◽  
pp. 164 ◽  
Author(s):  
Fei Zhao ◽  
Pinyi Li ◽  
Xiaoyan Liu ◽  
Xiuwen Jia ◽  
Jiang Wang ◽  
...  
Keyword(s):  
Transition Metal ◽  
Present Review ◽  
Reaction Conditions ◽  
Metal Free ◽  
Triple Bonds ◽  
Recent Advances ◽  
Direct Functionalization ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

The addition of amide/sulfonamide bonds to alkynes is not only one of the most important strategies for the direct functionalization of carbon–carbon triple bonds, but also a powerful tool for the downstream transformations of amides/sulfonamides. The present review provides a comprehensive summary of amide/sulfonamide bond addition to alkynes, including direct and metal-free aminoacylation, based-promoted aminoacylation, transition-metal-catalyzed aminoacylation, organocatalytic aminoacylation and transition-metal-catalyzed aminosulfonylation of alkynes up to December 2018. The reaction conditions, regio- and stereoselectivities, and mechanisms are discussed and summarized in detail.

Transition-metal-catalyzed direct β-functionalization of simple carbonyl compounds

2014 ◽  
Vol 1 (7) ◽  
pp. 838-842 ◽  
Author(s):  
Guobing Yan ◽  
Arun Jyoti Borah
Keyword(s):  
Transition Metal ◽  
Carbonyl Compounds ◽  
Bond Activation ◽  
Active Area ◽  
Synthetic Chemistry ◽  
Chemical Transformations ◽  
Recent Advances ◽  
Direct Functionalization ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

Chemical transformations via catalytic C–H bond activation have been established as one of the most powerful tools in organic synthetic chemistry. Transition-metal-catalyzed direct functionalization of β-C(sp3)–H bonds of carbonyl compounds has been developed in recent years. This highlight will focus on recent advances in this active area and their mechanisms are also discussed.

Formal nucleophilic borylation and borylative cyclization of organic halides

2017 ◽  
Vol 15 (2) ◽  
pp. 285-300 ◽  
Author(s):  
K. Kubota ◽  
H. Iwamoto ◽  
H. Ito
Keyword(s):  
Transition Metal ◽  
Metal Free ◽  
Recent Advances ◽  
Organic Halides ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

Recent advances in borylations of organic halides, including both transition-metal-catalyzed and metal-free methods are summarized. Borylative cyclization is also discussed.

Recent Advances in Direct C–H Functionalization of Pyrimidines

Synthesis ◽  
2017 ◽  
Vol 50 (02) ◽  
pp. 193-210 ◽  
Author(s):  
Egor Verbitskiy ◽  
Gennady Rusinov ◽  
Oleg Chupakhin ◽  
Valery Charushin
Keyword(s):  
Transition Metal ◽  
Pyrimidine Derivatives ◽  
Metal Free ◽  
Recent Advances ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

Data spanning the period 2000–2017 on the direct C–H functionalization of pyrimidines are collected and discussed in this review. This demonstrates the surge of interest and creativity that this field of chemistry has experienced during the last two decades. Plausible applications of highly functionalized pyrimidines are also discussed.1 Introduction2 Transition-Metal-Catalyzed C–H Functionalization of Pyrimidine Derivatives3 Transition-Metal-Free Direct C–H Functionalization of Pyrimidine Derivatives4 Deprotonative Metalation of Pyrimidine Derivatives5 Conclusions

Recent advances in the functionalization of polyfluoro(aza)aromatics via C–C coupling strategies

2021 ◽  
Author(s):  
Timofey D. Moseev ◽  
Mikhail V. Varaksin ◽  
Denis A. Gorlov ◽  
Valery N. Charushin ◽  
Oleg N. Chupakhin
Keyword(s):  
Transition Metal ◽  
Coupling Reactions ◽  
Metal Free ◽  
Recent Advances ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed ◽  
Coupling Strategies

This review highlights the recent advances in the functionalization of polyfluoro(aza)aromatics via both transition metal-catalyzed and metal-free C–C coupling reactions for the period from 2006 to the beginning of 2021.

scholarly journals Recent advances on the transition-metal-catalyzed synthesis of imidazopyridines: an updated coverage

2019 ◽  
Vol 15 ◽  
pp. 1612-1704 ◽  
Author(s):  
Gagandeep Kour Reen ◽  
Ashok Kumar ◽  
Pratibha Sharma
Keyword(s):  
Transition Metal ◽  
Transition Metals ◽  
Method Development ◽  
Deep Understanding ◽  
Catalyst Loading ◽  
Coupling Reactions ◽  
Reaction Conditions ◽  
Recent Advances ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

A comprehensive account of recent advances in the synthesis of imidazopyridines, assisted through transition-metal-catalyzed multicomponent reactions, C–H activation/functionalization and coupling reactions are highlighted in this review article. The basic illustration of this review comprises of schemes with concise account of explanatory text. The schemes depict the reaction conditions along with a quick look into the mechanism involved to render a deep understanding of the catalytic role. At some instances optimizations of certain features have been illustrated through tables, i.e., selectivity of catalyst, loading of the catalyst and percentage yield with different substrates. Each of the reported examples has been rigorously analyzed for reacting substrates, reaction conditions and transition metals used as the catalyst. This review will be helpful to the chemists in understanding the challenges associated with the reported methods as well as the future possibilities, both in the choice of substrates and catalysts. This review would be quite appealing to a wider range of organic chemists in academia and industrial R&D sectors working in the field of heterocyclic syntheses. In a nutshell, this review will be a guiding torch to envisage: (i) the role of various transition metals in the domain dedicated towards method development and (ii) for the modifications needed thereof in the R&D sector.

ChemInform Abstract: Recent Advances in Metal Free- and Late Transition Metal-Catalyzed Hydroamination of Unactivated Alkenes

ChemInform ◽  
2015 ◽  
Vol 46 (23) ◽  
pp. no-no
Author(s):  
Elise Bernoud ◽  
Clement Lepori ◽  
Mohamed Mellah ◽  
Emmanuelle Schulz ◽  
Jerome Hannedouche
Keyword(s):  
Transition Metal ◽  
Late Transition Metal ◽  
Metal Free ◽  
Recent Advances ◽  
Transition Metal Catalyzed ◽  
Late Transition ◽  
Metal Catalyzed

Chelation-assisted transition metal-catalysed C–H chalcogenylations

2020 ◽  
Vol 7 (8) ◽  
pp. 1022-1060 ◽  
Author(s):  
Wenbo Ma ◽  
Nikolaos Kaplaneris ◽  
Xinyue Fang ◽  
Linghui Gu ◽  
Ruhuai Mei ◽  
...  
Keyword(s):  
Transition Metal ◽  
Recent Advances ◽  
Site Selectivity ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

This review summarizes recent advances in C–S and C–Se formations via transition metal-catalyzed C–H functionalization utilizing directing groups to control the site-selectivity.

Recent advances in transition metal-catalyzed asymmetric electrocatalysis

2021 ◽  
Vol 444 ◽  
pp. 214065
Author(s):  
Priyanka Chakraborty ◽  
Rajib Mandal ◽  
Nidhi Garg ◽  
Basker Sundararaju
Keyword(s):  
Transition Metal ◽  
Recent Advances ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

scholarly journals Transition metal-catalyzed synthesis of spirooxindoles

RSC Advances ◽  
2021 ◽  
Vol 11 (13) ◽  
pp. 7146-7179
Author(s):  
P. V. Saranya ◽  
Mohan Neetha ◽  
Thaipparambil Aneeja ◽  
Gopinathan Anilkumar
Keyword(s):  
Transition Metal ◽  
Transition Metals ◽  
Antimicrobial Agents ◽  
Recent Advances ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

Spirooxindoles are used as anticancer-, antiviral-, antimicrobial agents etc. The use of transition metals as catalysts for the synthesis of spirooxindoles is advancing rapidly. Here, we focus on recent advances in transition metal-catalyzed synthesis of spirooxindoles.

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