scholarly journals Phytochemical Profile and Biological Activities of Satureja hortensis L.: A Review of the Last Decade

Molecules ◽  
2018 ◽  
Vol 23 (10) ◽  
pp. 2458 ◽  
Author(s):  
Irina Fierascu ◽  
Cristina Elena Dinu-Pirvu ◽  
Radu Claudiu Fierascu ◽  
Bruno Stefan Velescu ◽  
Valentina Anuta ◽  
...  

Satureja hortensis L. (summer savory) is an annual herbaceous crop, native to Europe and in our days spread and used all over the world. Although its use as spice and medicinal plant is known since ancient times, peer-reviewed studies presenting the scientific data are scarce. The natural products obtained from summer savory (extracts and essential oil) are dominated by polyphenols and flavonoids, responsible for their antioxidant, antimicrobial, antiparasitic, pesticidal, anti-inflammatory, analgesic, hepatoprotective and anticancer properties, among others. The current study presents the progress made in the last decade regarding the potential applications of summer savory, being the first review study focused on S. hortensis, in the same time suggesting future research opportunities, as they appear from the properties of other Satureja species. The available data presenting the properties of summer savory represents a scientific support for application in industry, for developing “clean label” food products.

2023 ◽  
Vol 55 (1) ◽  
pp. 1-39
Author(s):  
Thanh Tuan Nguyen ◽  
Thanh Phuong Nguyen

Representing dynamic textures (DTs) plays an important role in many real implementations in the computer vision community. Due to the turbulent and non-directional motions of DTs along with the negative impacts of different factors (e.g., environmental changes, noise, illumination, etc.), efficiently analyzing DTs has raised considerable challenges for the state-of-the-art approaches. For 20 years, many different techniques have been introduced to handle the above well-known issues for enhancing the performance. Those methods have shown valuable contributions, but the problems have been incompletely dealt with, particularly recognizing DTs on large-scale datasets. In this article, we present a comprehensive taxonomy of DT representation in order to purposefully give a thorough overview of the existing methods along with overall evaluations of their obtained performances. Accordingly, we arrange the methods into six canonical categories. Each of them is then taken in a brief presentation of its principal methodology stream and various related variants. The effectiveness levels of the state-of-the-art methods are then investigated and thoroughly discussed with respect to quantitative and qualitative evaluations in classifying DTs on benchmark datasets. Finally, we point out several potential applications and the remaining challenges that should be addressed in further directions. In comparison with two existing shallow DT surveys (i.e., the first one is out of date as it was made in 2005, while the newer one (published in 2016) is an inadequate overview), we believe that our proposed comprehensive taxonomy not only provides a better view of DT representation for the target readers but also stimulates future research activities.


Planta Medica ◽  
2018 ◽  
Vol 84 (09/10) ◽  
pp. 627-637 ◽  
Author(s):  
Rosa Tundis ◽  
Monica Loizzo

AbstractThe genus Santolina is a taxonomically complex group of plant species widely distributed in the Mediterranean flora and used in traditional medicine since ancient times for their biological properties, including antimicrobial, anti-inflammatory, antispasmodic, digestive, and analgesic activities. Phytochemical investigations of Santolina species have revealed the presence of terpenoids as the main bioactive constituents of the genus. Coumarins and flavonoids were also identified. This review deals, for the first time, with information on the traditional uses, chemical profile, and biological properties of plants of the genus Santolina in order to provide input for future research prospects.


2019 ◽  
Vol 6 (4) ◽  
pp. 373-382 ◽  
Author(s):  
Fazal Ullah ◽  
Asma Ayaz ◽  
Saddam Saqib ◽  
Wajid Zaman ◽  
Maryam Akram Butt ◽  
...  

Silene conoidea L. is a weed commonly grown in subtropical and temperate zone of western Eurasia, and some part of Himalaya. S. conoidea is a small herb height from 20 to 40cm mostly grow as weed in different crops like wheat, barley, mustard, roquette and lentil pea. This is the first attempt to gather utmost information about the species distribution, taxonomy, ethno-medicines, phytochemical analysis, biological activity etc. of Silene conoidea. The present review aim was to collect fragmented information about the species in addition to explore its therapeutic importance in future research opportunities. A total of 100 research articles were reviewed using different sources like; Scopus, web of science, Science direct, google scholar and PubMed. The species are used as multipurpose in different biological activities against microbes, bacteria and as insecticidal. Silene is also important due to high contents of various chemicals compounds. Chemical extracts contain flavones, glycosides, saponins, sterols and glycosides. A research study shows that S. conoidea can be used as an indicator species of gold. Traditional therapeutic values of the species for treating respiratory, antioxidant, anti-diabetic and anticancer are needed to be validated through more research. Ethno-pharmacological and clinical trial research can be subjected for future studies.


2020 ◽  
Vol 23 (7) ◽  
pp. 624-648
Author(s):  
Kamal Kant ◽  
Uma R. Lal ◽  
Ravi Rawat ◽  
Anoop Kumar ◽  
Manik Ghosh

Background: The Arisaema (Araceae) is a genus of approximately 180 perennial herbs widely distributed in the evergreen and deciduous forests. This genus (Arisaema) has been used as a medicinal agent since ancient times. Experimental investigations have shown a promising positive correlation with its folklore claim and this encourages us to report updated medicinal review (genus Arisaema) for future research. Objective: This review aimed to summarize the ethnobotany, folklore uses, chemistry and biological activities. Conclusion: The comprehensive literature on genus Arisaema indicates the presence of terpenoids, flavonoids, and glycosphingolipids as the principal chemical constituents. Additionally, phytosterols, alkaloids, carboline derivatives and miscellaneous compounds were documented in plants of genus Arisaema. Biological investigations led to the credentials of antioxidant, anticancer, insecticidal, antimicrobial, anthelmintic and hepatoprotective activities. Following, several plant species are promising candidates for the treatment of cancer, parasitic diseases and microbial infection complications. Though, a lot of facets of this genus like phytoconstituents identification, mechanistic profile, adverse effects and clinical studies are still quite limited. Thus, this systematic review may act as a powerful tool in future studies for promoting health benefits against various health hazards.


2014 ◽  
Vol 6 (4) ◽  
pp. 395-398 ◽  
Author(s):  
Anestis KARKANIS ◽  
Evangelos VELLIOS ◽  
Thomas THOMAIDIS ◽  
Dimitrios BILALIS ◽  
Aspasia EFTHIMIADOU ◽  
...  

Great burnet (Sanguisorba officinalis L.) and small burnet (Sansguisorba minor Scop.) are edible, perennial weeds widely distributed in the world. These are the most widespread Sanguisorba species. The bioactive components of Sanguisorba plants include phenolics (phenolic acids, flavonoids and neolignans) and terpenoids. Large potential exists to use burnets as medicinal plants. Sanguisorba species are known to show anticancer properties, antioxidative, antimicrobial and antiviral activities. Also, Sanguisorba extracts show anti-Alzheimer and anti-inflammatory properties. Small burnet extracts could also be a useful alternative to synthetic fungicides for crop production. This review focuses on biological activities of Sanguisorba extracts and emphasizing their potential applications in pharmaceutical areas.


2021 ◽  
Vol 15 (1) ◽  
pp. 50
Author(s):  
Łukasz Świątek ◽  
Elwira Sieniawska ◽  
Mohamad Fawzi Mahomoodally ◽  
Nabeelah Bibi Sadeer ◽  
Krzysztof Kamil Wojtanowski ◽  
...  

This study presents the evaluation of biological activities and chemical profiling of Oenanthe aquatica (L.) Poir. and Oenanthe silaifolia M. Bieb. The phytochemical profile, antioxidant, enzyme inhibitory, cytotoxic and antiviral activities of the methanolic and aqueous extracts were investigated. The aqueous extract of O. aquatica possessing the highest content of phenolics (60.85 mg gallic acid equivalent/g extract), also exhibited the strongest radical scavenging potential against 2,2-diphenyl-1-picrylhydrazyl and 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (79.46 and 148.66 mg Trolox equivalent/g extract, respectively), the highest reducing ability (207.59 and 107.27 mg Trolox equivalent/g extract, for cupric reducing antioxidant capacity and ferric reducing antioxidant activity, respectively), metal chelating potential (33.91 mg ethylenediaminetetraacetic acid equivalent/g extract) and total antioxidant ability (1.60 mmol Trolox equivalent/g extract). Liquid chromatography-electrospray ionization-quadrupole time-of-flight-mass spectrometry (LC-ESI-QTOF-MS/MS) permitted tentative identification of compounds from simple organic acids, phenolic acids, coumarins, flavonoids and their glycosides in O. aquatica and O. silaifolia extracts. The methanolic extract of O. aquatica substantially depressed acetylcholinesterase (3.67 mg galantamine equivalent/g extract), tyrosinase (126.66 mg kojic acid equivalent/g extract), and α-amylase (0.83 mmol acarbose equivalent/g extract) enzymes. The methanolic extract of O. silaifolia showed highest enzymatic inhibitory property against butyrylcholinesterase, and its aqueous extract depressed α-glucosidase activity (0.26 mmol acarbose equivalent/g extract). All tested extracts exerted selective toxicity towards cancer cell lines, and the highest anticancer potential was found for O. aquatica aqueous extract on FaDu and HeLa cells with CC50 of 57.36 and 47.16 µg/mL, respectively. Significant antiviral activity against HSV-1 (HHV-1) was found for both aqueous extracts in concentrations of 1000 µg/mL, which inhibited the HSV-1 cytopathic effect (CPE) in virus infected VERO cells and reduced the virus infective titer by more than 3 log (logCCID50/mL). This study has produced critical scientific data on O. aquatica and O. silaifolia, which are potential contenders for the development of novel phyto-pharmaceuticals.


Marine Drugs ◽  
2021 ◽  
Vol 19 (9) ◽  
pp. 511
Author(s):  
Sarah Giovanna Montenegro Lima ◽  
Marjorie Caroline Liberato Cavalcanti Freire ◽  
Verônica da Silva Oliveira ◽  
Carlo Solisio ◽  
Attilio Converti ◽  
...  

Astaxanthin (AST) is a biomolecule known for its powerful antioxidant effect, which is considered of great importance in biochemical research and has great potential for application in cosmetics, as well as food products that are beneficial to human health and medicines. Unfortunately, its poor solubility in water, chemical instability, and low oral bioavailability make its applications in the cosmetic and pharmaceutical field a major challenge for the development of new products. To favor the search for alternatives to enhance and make possible the use of AST in formulations, this article aimed to review the scientific data on its application in delivery systems. The search was made in databases without time restriction, using keywords such as astaxanthin, delivery systems, skin, cosmetic, topical, and dermal. All delivery systems found, such as liposomes, particulate systems, inclusion complexes, emulsions, and films, presented peculiar advantages able to enhance AST properties, among which are stability, antioxidant potential, biological activities, and drug release. This survey showed that further studies are needed for the industrial development of new AST-containing cosmetics and topical formulations.


2021 ◽  
Vol 2021 ◽  
pp. 1-18
Author(s):  
Luiz Renan Ramos da Silva ◽  
Oberdan Oliveira Ferreira ◽  
Jorddy Nevez Cruz ◽  
Celeste de Jesus Pereira Franco ◽  
Tainá Oliveira dos Anjos ◽  
...  

Medicinal and aromatic plants present important active compounds that have potential for use in food, pharmaceutical, and agriculture industries. In this sense, the present work aimed to conduct a literature review on the potential applications of essential oils from Lamiaceae species. Antioxidant, anti-inflammatory, and antimicrobial activities were evaluated. The importance of this study is demonstrated as a way to theoretically provide information on the use of different plants belonging to the Lamiaceae family, especially with regard to the physical, chemical, and biological properties of its essential oils.


2020 ◽  
Author(s):  
Yunzhong Wang ◽  
Saixing Tang ◽  
Yating Wen ◽  
Shuyuan Zheng ◽  
Bing Yang ◽  
...  

<div>Persistent room-temperature phosphorescence (p-RTP) from pure organics is attractive </div><div>due to its fundamental importance and potential applications in molecular imaging, </div><div>sensing, encryption, anticounterfeiting, etc.1-4 Recently, efforts have been also made in </div><div>obtaining color-tunable p-RTP in aromatic phosphors5 and nonconjugated polymers6,7. </div><div>The origin of color-tunable p-RTP and the rational design of such luminogens, </div><div>particularly those with explicit structure and molecular packing, remain challenging. </div><div>Noteworthily, nonconventional luminophores without significant conjugations generally </div><div>possess excitation-dependent photoluminescence (PL) because of the coexistence of </div><div>diverse clustered chromophores6,8, which strongly implicates the possibility to achieve </div><div>color-tunable p-RTP from their molecular crystals assisted by effective intermolecular </div><div>interactions. Here, inspirited by the highly stable double-helix structure and multiple </div><div>hydrogen bonds in DNA, we reported a series of nonconventional luminophores based on </div><div>hydantoin (HA), which demonstrate excitation-dependent PL and color-tunable p-RTP </div><div>from sky-blue to yellowish-green, accompanying unprecedentedly high PL and p-RTP </div><div>efficiencies of up to 87.5% and 21.8%, respectively. Meanwhile, the p-RTP emissions are </div><div>resistant to vigorous mechanical grinding, with lifetimes of up to 1.74 s. Such robust, </div><div>color-tunable and highly efficient p-RTP render the luminophores promising for varying </div><div>applications. These findings provide mechanism insights into the origin of color-tunable </div><div>p-RTP, and surely advance the exploitation of efficient nonconventional luminophores.</div>


2020 ◽  
Vol 27 (35) ◽  
pp. 5970-6014 ◽  
Author(s):  
Md. Jawaid Akhtar ◽  
Mohammad Shahar Yar ◽  
Vinod Kumar Sharma ◽  
Ahsan Ahmed Khan ◽  
Zulphikar Ali ◽  
...  

This review presents the detailed account of factors leading to cancer and design strategy for the synthesis of benzimidazole derivatives as anticancer agents. The recent survey for cancer treatment in Cancer facts and figures 2017 American Chemical Society has shown progressive development in fighting cancer. Researchers all over the world in both developed and developing countries are in a continuous effort to tackle this serious concern. Benzimidazole and its derivatives showed a broad range of biological activities due to their resemblance with naturally occurring nitrogenous base i.e. purine. The review discussed benzimidazole derivatives showing anticancer properties through a different mechanism viz. intercalation, alkylating agents, topoisomerases, DHFR enzymes, and tubulin inhibitors. Benzimidazole derivatives act through a different mechanism and the substituents reported from the earlier and recent research articles are prerequisites for the synthesis of targeted based benzimidazole derivatives as anticancer agents. The review focuses on an easy comparison of the substituent essential for potency and selectivity through SAR presented in figures. This will further provide a better outlook or fulfills the challenges faced in the development of novel benzimidazole derivatives as anticancer.


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