scholarly journals Review of Ethnomedicinal Uses, Phytochemistry and Pharmacological Properties of Euclea natalensis A.DC.

Molecules ◽  
2017 ◽  
Vol 22 (12) ◽  
pp. 2128 ◽  
Author(s):  
Alfred Maroyi
2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Félicien Mushagalusa Kasali ◽  
Jonans Tusiimire ◽  
Justin Ntokamunda Kadima ◽  
Amon Ganafa Agaba

Abstract Background The Chenopodium genus is a plant family widely spread worldwide that includes various plant species reputed to possess several medicinal virtues in folk medicines. Chenopodium ambrosioides L. is among the most used plants in traditional medicines worldwide. This review aimed to highlight ethnomedicinal uses, phytochemical status, and pharmacological properties of C. ambrosioides L. Main body of the abstract The analysis of relevant data highlights various ethnomedicinal uses against human and veterinary diseases in forty countries. Most indications consisted of gastrointestinal tract dysfunctioning troubles and worms parasitemia. Around 330 chemical compounds have been identified in different plant parts, especially in its essential oil fractions (59.84%). However, only a few compounds—mainly monoterpenes and glycosides—have been isolated and characterized. Experimental pharmacological studies validated a large scale of significant health benefits. It appeared that many monoterpenes are antioxidant, insecticidal, trypanocidal, analgesic, antifungal, anti-inflammatory, anti-arthritic, acaricidal, amoebicidal, anthelmintic, anticancer, antibacterial, antidiabetic, antidiarrheal, antifertility, antifungal, anti-leishmanial, antimalarial, antipyretic, antisickling, antischistosomal, antiulcer, anxiolytic, immunomodulatory, molluscicidal, and vasorelaxant agents. Short conclusion Thus, the Chenopodium ambrosioides species necessitates further chemical studies to isolate and characterize new bioactive secondary metabolites and pharmacological investigations to precise the mechanisms of action before clinical trials.


Author(s):  
Alfred Maroyi

Lannea discolor is an important component of the traditional, complementary, and alternative medicine health-care systems in several countries. This study is aimed at reviewing the botany, ethnomedicinal uses, phytochemical and biological activities of L. discolor. Information on its botany, medicinal uses, chemistry and pharmacological properties was undertaken using electronic databases such as Pubmed, SCOPUS, Medline, SciFinder, ScienceDirect, Google Scholar, EThOS, ProQuest, OATD and Open-thesis. Pre-electronic literature was sourced from the University Library. The species is used as herbal medicine for 24 human diseases. The major diseases and ailments treated using concoctions prepared from L. discolor include gastrointestinal problems, gonorrhea, infertility in women, convulsions, dizziness, injury, and wounds. Different aqueous and organic extracts of L. discolor exhibited anthelmintic, antibacterial, antimycobacterial, antifungal, antioxidant, antiplasmodial, and nematicidal activities. Detailed studies on the phytochemistry, pharmacological, and toxicological properties of L. discolor are required to correlate the medicinal uses of the species with its phytochemistry and pharmacological properties.


2017 ◽  
Vol 55 (1) ◽  
pp. 1093-1113 ◽  
Author(s):  
Ihsan N. Zulkipli ◽  
Rajan Rajabalaya ◽  
Adi Idris ◽  
Nurul Atiqah Sulaiman ◽  
Sheba R. David

Molecules ◽  
2019 ◽  
Vol 24 (4) ◽  
pp. 732 ◽  
Author(s):  
Alfred Maroyi

Lannea schweinfurthii is a valuable medicinal plant species among different ethnic groups in tropical Africa. The aim of the current study was to review existing literature on the ethnomedicinal uses, phytochemistry and pharmacological properties of L. schweinfurthii in an effort to evaluate the therapeutic potential of the species. The relevant information on the ethnomedicinal uses, phytochemistry and pharmacological properties of L. schweinfurthii was generated from several sources including books, book chapters, theses, scientific reports and journal articles obtained from the library and internet sources such as SciFinder, Wiley, Web of Science, American Chemical Society publications, PubMed, BMC, Elsevier, Science Direct, Scielo and Scopus. Traditionally, L. schweinfurthii is used against reproductive system disorders, respiratory disorders, injuries, headache, blood system disorders, infections or infestations and gastro-intestinal disorders. The phytochemical compounds that have been isolated from L. schweinfurthii include alkaloids, anthocyanins, flavonoids, glycosides, phenols, saponins, steroids, tannins and terpenoids. The in vitro and animal studies carried out so far from the crude extracts and compounds isolated from the species exhibited acetylcholinesterase inhibitory, anti-apoptotic, antibacterial, antiviral, anti-giardial, anti-inflammatory, antioxidant, antiplasmodial, antitrypanosomal, hepatoprotective, larvicidal and cytotoxicity activities. Detailed ethnopharmacological studies emphasizing clinical and toxicological evaluations are needed to assess efficacy and safety of the species as herbal medicine.


2021 ◽  
Vol 12 (3) ◽  
pp. 147-156
Author(s):  
Shailja Choudhary ◽  
Gitika Chaudhary ◽  
Hemlata Kaurav

Aegle marmelos is considered as the most sacred or holy plant which is grown by the sides of Hindu temples. This plant is dedicated to Lord Shiva and is also believed that Lord Shiva resides under the Bael tree. Besides this, the plant is associated with a great medicinal value whose medicinal description is also mentioned in the ancient treatise like Vedas, Puranas, Charaka Samhita and Brihat Samhita and has also been portrayed in the paintings of Ajanta caves. Every part of the Bael plant is used to treat various diseases. In Ayurveda, the plant is used in Panchang form to treat diarrhea, dysentery and ulcer. In folklore, the plant parts are used to treat diabetes, skin diseases and typhoid, wound healing, ulcer, stomachache, jaundice, high BP, malaria, cancer and other diseases. The fruit of the plant is edible and carries great medicinal value because of the presence of vitamins, minerals and various antioxidants. The pulp of the fruit is aromatic, sweet, pale orange and resinous. The unripe fruit pulp of the plant is used to prepare murabba, pudding and juice. The plant is associated with ethnomedicinal uses and possesses various therapeutic and pharmacological properties including antioxidant, anti-diabetic, antihistamine, radio protective, antiulcer, anticancer, cardio-protective, antidiarrheal, antibacterial, antimicrobial, hepatoprotective, anti-inflammatory and antiviral. In this review article, attempts have been made to summarize the phytochemistry, ethnomedicinal, Ayurvedic and pharmacological view of the Bael plant.


Molecules ◽  
2020 ◽  
Vol 25 (17) ◽  
pp. 4019
Author(s):  
Douglas Kemboi ◽  
Xolani Peter ◽  
Moses Langat ◽  
Jacqueline Tembu

The genus Euphorbia is one of the largest genera in the spurge family, with diversity in range, distribution, and morphology. The plant species in this genus are widely used in traditional medicine for the treatment of diseases, ranging from respirational infections, body and skin irritations, digestion complaints, inflammatory infections, body pain, microbial illness, snake or scorpion bites, pregnancy, as well as sensory disorders. Their successes have been attributed to the presence of diverse phytochemicals like polycyclic and macrocyclic diterpenes with various pharmacological properties. As a result, Euphorbia diterpenes are of interest to chemists and biochemists with regard to drug discovery from natural products due to their diverse therapeutic applications as well as their great structural diversity. Other chemical constituents such as triterpenoids have also been reported to possess various pharmacological properties, thus supporting the traditional uses of the Euphorbia species. These triterpenoids can provide potential leads that can be developed into pharmaceutical compounds for a wide range of medicinal applications. However, there are scattered scientific reports about the anticancer activities of these constituents. Harnessing such information could provide a database of bioactive pharmacopeia or targeted scaffolds for drug discovery. Therefore, this review presents an updated and comprehensive summary of the ethnomedicinal uses, phytochemistry, and the anticancer activities of the triterpenoids of Euphorbia species. Most of the reported triterpenoids in this review belong to tirucallane, cycloartanes, lupane, oleanane, ursane, and taraxane subclass. Their anticancer activities varied distinctly with the majority of them exhibiting significant cytotoxic and anticancer activities in vitro. It is, therefore, envisaged that the report on Euphorbia triterpenoids with interesting anticancer activities will form a database of potential leads or scaffolds that could be advanced into the clinical trials with regard to drug discovery.


Author(s):  
Alfred Maroyi

Dicoma anomala is used as herbal medicine to treat and manage fever, coughs, colds, sore throats, abdominal pain, diarrhea, dysentery, constipation, intestinal worms, and sexually transmitted infections in tropical Africa. The aim of this study was to summarize the research that has been done on the ethnomedicinal uses, phytochemistry, and pharmacological properties of D. anomala in tropical Africa. The literature search for information on ethnomedicinal uses and pharmacological activities of D. anomala was undertaken using databases such as Web of Science, Scopus, Google Scholar, Science Direct, BioMed Central, PubMed, and Springer link. Other relevant literature sources included books, book chapters, websites, theses, conference papers, and other scientific publications. This study showed that D. anomala is used as herbal medicine in 57.1% of the countries in tropical Africa where it is indigenous. The species is used to treat 66 and five human and animal diseases, respectively. Several classes of secondary metabolites including acetylenic compounds, diterpene, flavonoids, phenols, phytosterols, saponins, sesquiterpenes, tannins and triterpenes have been isolated from D. anomala. Different aqueous and organic extracts of D. anomala exhibited anthelmintic, anticancer, antihyperglycemic, anti-inflammatory, antimicrobial, antioxidant, antiplasmodial, and hepatoprotective activities. The documented information on the botany, ethnomedicinal uses, phytochemistry, and pharmacological properties of D. anomala provide baseline data required for further ethnopharmacological studies on the species.


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