scholarly journals Development, Physicochemical Characterization and In Vitro Anti-Inflammatory Activity of Solid Dispersions of α,β Amyrin Isolated from Protium Oilresin

Molecules ◽  
2017 ◽  
Vol 22 (9) ◽  
pp. 1512 ◽  
Author(s):  
Walter da Silva Júnior ◽  
Jonas Pinheiro ◽  
Danielle de Menezes ◽  
Natan e Silva ◽  
Patrícia de Almeida ◽  
...  
Keyword(s):  
Solid Dispersions ◽  
Physicochemical Characterization ◽  
Inflammatory Activity ◽  
Anti Inflammatory

scholarly journals Inclusion Complexes of β and HPβ-Cyclodextrin with α, β Amyrin and In Vitro Anti-Inflammatory Activity

Biomolecules ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. 241 ◽  
Author(s):  
Walter Ferreira da Silva Júnior ◽  
Danielle Lima Bezerra de Menezes ◽  
Luana Carvalho de Oliveira ◽  
Letícia Scherer Koester ◽  
Patrícia Danielle Oliveira de Almeida ◽  
...  
Keyword(s):  
Inclusion Complexes ◽  
Biological Activities ◽  
Physicochemical Characterization ◽  
Inflammatory Activity ◽  
Scanning Calorimetry ◽  
Promising Alternative ◽  
Wide Range ◽  
Natural Mixture ◽  
Anti Inflammatory

α, β amyrin (ABAM) is a natural mixture of pentacyclic triterpenes that has a wide range of biological activities. ABAM is isolated from the species of the Burseraceae family, in which the species Protium is commonly found in the Amazon region of Brazil. The aim of this work was to develop inclusion complexes (ICs) of ABAM and β-cyclodextrin (βCD) and hydroxypropyl-β-cyclodextrin (HPβCD) by physical mixing (PM) and kneading (KN) methods. Interactions between ABAM and the CD’s as well as the formation of ICs were confirmed by physicochemical characterization in the solid state by Fourier transform infrared (FTIR), scanning electron microscopy (SEM), X-ray diffraction (XRD), thermogravimetry (TG) and differential scanning calorimetry (DSC). Physicochemical characterization indicated the formation of ICs with both βCD and HPβCD. Such ICs were able to induce changes in the physicochemical properties of ABAM. In addition, the formation of ICs with cyclodextrins showed to be an effective and promising alternative to enhance the anti-inflammatory activity and safety of ABAM.

In vitro anti-inflammatory activity of extracts from seeds of some Nigella species

Planta Medica ◽  
2007 ◽  
Vol 73 (09) ◽  
Author(s):  
P Landa ◽  
P Marsik ◽  
T Vanek ◽  
L Kokoska
Keyword(s):  
Inflammatory Activity ◽  
Anti Inflammatory

In Vitro Anti-inflammatory Activity of Selected Japanese Higher Basidiomycetes Mushrooms

2008 ◽  
Vol 10 (1) ◽  
pp. 49-53 ◽  
Author(s):  
Nitaro Maekawa ◽  
Esameldin E. Elgorashi ◽  
Hiroshi Satoh
Keyword(s):  
Inflammatory Activity ◽  
Anti Inflammatory

Synthesis and anti-inflammatory activity of novel steroidal chalcones with 3β-pregnenolone ester derivatives in RAW 264.7 cells in vitro

Steroids ◽  
2021 ◽  
pp. 108830
Author(s):  
Xiaorui Cai ◽  
Fei Sha ◽  
Chuanyi Zhao ◽  
Zhiwei Zheng ◽  
Shulin Zhao ◽  
...  
Keyword(s):  
Inflammatory Activity ◽  
Raw 264.7 Cells ◽  
Raw 264.7 ◽  
Anti Inflammatory

scholarly journals Seasonal dynamics of the phenolic constituents of the cones and leaves of oriental Thuja (Platycladus orientalis L.) reveal their anti-inflammatory biomarkers

RSC Advances ◽  
2021 ◽  
Vol 11 (40) ◽  
pp. 24624-24635
Author(s):  
Reham S. Darwish ◽  
Hala M. Hammoda ◽  
Doaa A. Ghareeb ◽  
Ali S. A. Abdelhamid ◽  
Fathallah M. Harraz ◽  
...  
Keyword(s):  
Seasonal Dynamics ◽  
Inflammatory Biomarkers ◽  
Inflammatory Activity ◽  
Platycladus Orientalis ◽  
Phenolic Constituents ◽  
Anti Inflammatory

In this study, the seasonal dynamics of the flavonoids in the cones and leaves of oriental Thuja (Platycladus orientalis L. Franco) as well as the in vitro anti-inflammatory activity of their extracts were investigated.

scholarly journals Phytochemical Analysis, Antioxidant and Anti-Inflammatory Activity of Calyces from Physalis peruviana

2014 ◽  
Vol 9 (11) ◽  
pp. 1934578X1400901 ◽  
Author(s):  
Reina M. Toro ◽  
Diana M. Aragón ◽  
Luis F. Ospina ◽  
Freddy A. Ramos ◽  
Leonardo Castellanos
Keyword(s):  
Antioxidant Activities ◽  
Folk Medicine ◽  
Ethanolic Extract ◽  
Inflammatory Activity ◽  
Phytochemical Analysis ◽  
Physalis Peruviana ◽  
Edema Model ◽  
Anti Inflammatory ◽  
Bio Assay

Physalis peruviana calyces are used extensively in folk medicine. The crude ethanolic extract and some fractions of calyces were evaluated in order to explore antioxidant and anti-inflammatory activities. The anti-inflammatory activity was evaluated by the TPA-induced ear edema model. The antioxidant in vitro activity was measured by means of the superoxide and nitric oxide scavenging activity of the extracts and fractions. The butanolic fraction was found to be promising due to its anti-inflammatory and antioxidant activities. Therefore, a bio-assay guided approach was employed to isolate and identify rutin (1) and nicotoflorin (2) from their NMR spectroscopic and MS data. The identification of rutin in calyces of P. peruviana supports the possible use of this waste material for phytotherapeutic, nutraceutical and cosmetic preparations.

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