Novel Anthranilamide-Based FXa Inhibitors: Drug Design, Synthesis and Biological Evaluation

Wenzhi Wang; Jing Yuan; Xiaoli Fu; Fancui Meng; Shijun Zhang; Weiren Xu; Yongnan Xu; Changjiang Huang

doi:10.3390/molecules21040491

Novel Anthranilamide-Based FXa Inhibitors: Drug Design, Synthesis and Biological Evaluation

Molecules ◽

10.3390/molecules21040491 ◽

2016 ◽

Vol 21 (4) ◽

pp. 491 ◽

Cited By ~ 6

Author(s):

Wenzhi Wang ◽

Jing Yuan ◽

Xiaoli Fu ◽

Fancui Meng ◽

Shijun Zhang ◽

...

Keyword(s):

Drug Design ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Corrigendum to “Thioether benzenesulfonamide inhibitors of carbonic anhydrases II and IV: Structure-based drug design, synthesis, and biological evaluation” [Bioorg. Med. Chem. 18 (2010) 3307]

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2010.08.015 ◽

2010 ◽

Vol 18 (19) ◽

pp. 7144 ◽

Cited By ~ 2

Author(s):

William F. Vernier ◽

Wesley K.M. Chong ◽

David A. Rewolinski ◽

Samantha E. Greasley ◽

Thomas A. Pauly ◽

...

Keyword(s):

Drug Design ◽

Biological Evaluation ◽

Carbonic Anhydrases ◽

Structure Based Drug Design ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Rational drug design, synthesis, and biological evaluation of novel chiral tetrahydronaphthalene-fused spirooxindole as MDM2-CDK4 dual inhibitor against glioblastoma

Acta Pharmaceutica Sinica B ◽

10.1016/j.apsb.2019.12.013 ◽

2020 ◽

Vol 10 (8) ◽

pp. 1492-1510 ◽

Cited By ~ 2

Author(s):

Biao Wang ◽

Fu Peng ◽

Wei Huang ◽

Jin Zhou ◽

Nan Zhang ◽

...

Keyword(s):

Drug Design ◽

Biological Evaluation ◽

Rational Drug Design ◽

Dual Inhibitor ◽

Design Synthesis ◽

Rational Drug ◽

Synthesis And Biological Evaluation

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Rational drug design, synthesis and biological evaluation of dihydrofolate reductase inhibitors as antituberculosis agents

Future Medicinal Chemistry ◽

10.4155/fmc.15.48 ◽

2015 ◽

Vol 7 (8) ◽

pp. 979-988 ◽

Cited By ~ 8

Author(s):

Nilesh R Tawari ◽

Seema Bag ◽

Archana Raju ◽

Arundhati C Lele ◽

Ranjeet Bairwa ◽

...

Keyword(s):

Drug Design ◽

Dihydrofolate Reductase ◽

Biological Evaluation ◽

Rational Drug Design ◽

Design Synthesis ◽

Reductase Inhibitors ◽

Rational Drug ◽

Synthesis And Biological Evaluation ◽

Dihydrofolate Reductase Inhibitors

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Identification of novel PARP-1 inhibitors: Drug design, synthesis and biological evaluation

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2015.08.060 ◽

2015 ◽

Vol 25 (20) ◽

pp. 4557-4561 ◽

Cited By ~ 12

Author(s):

Zhouling Xie ◽

Youli Zhou ◽

Wei Zhao ◽

He Jiao ◽

Yu Chen ◽

...

Keyword(s):

Drug Design ◽

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Parp 1

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Structure-based drug design: Synthesis and biological evaluation of quinazolin-4-amine derivatives as selective Aurora A kinase inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2018.08.053 ◽

2018 ◽

Vol 157 ◽

pp. 1361-1375 ◽

Cited By ~ 2

Author(s):

Liang Long ◽

Yong-Heng Wang ◽

Jun-Xiao Zhuo ◽

Zheng-Chao Tu ◽

Ruibo Wu ◽

...

Keyword(s):

Drug Design ◽

Kinase Inhibitors ◽

Biological Evaluation ◽

Aurora A Kinase ◽

Aurora A ◽

Structure Based Drug Design ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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Design, Synthesis and Biological Evaluation of Cyclic Angiotensin II Analogues with 3,5 Side-Chain Bridges: Role of C-Terminal Aromatic Residue and Ring Cluster for Activity and Implications in the Drug Design of AT1 Non-peptide Antagonists.

ChemInform ◽

10.1002/chin.200306177 ◽

2003 ◽

Vol 34 (6) ◽

Author(s):

Thomas Mavromoustakos ◽

et al. et al.

Keyword(s):

Angiotensin Ii ◽

Drug Design ◽

Biological Evaluation ◽

Side Chain ◽

Design Synthesis ◽

Aromatic Residue ◽

Angiotensin Ii Analogues ◽

Synthesis And Biological Evaluation

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Novel aminoarylthiazole derivatives as correctors of the chloride transport defect in cystic fibrosis: computer assisted drug design, synthesis and biological evaluation

Postdoc Journal ◽

10.14304/ffc2016proceedings.05 ◽

2016 ◽

Author(s):

Liessi N et al

Keyword(s):

Cystic Fibrosis ◽

Drug Design ◽

Chloride Transport ◽

Biological Evaluation ◽

Computer Assisted ◽

Design Synthesis ◽

Transport Defect ◽

Synthesis And Biological Evaluation

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Identification of anthranilamide derivatives as potential factor Xa inhibitors: Drug design, synthesis and biological evaluation

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2015.03.052 ◽

2015 ◽

Vol 95 ◽

pp. 388-399 ◽

Cited By ~ 15

Author(s):

Junhao Xing ◽

Lingyun Yang ◽

Hui Li ◽

Qing Li ◽

Leilei Zhao ◽

...

Keyword(s):

Drug Design ◽

Factor Xa ◽

Biological Evaluation ◽

Factor Xa Inhibitors ◽

Design Synthesis ◽

Potential Factor ◽

Synthesis And Biological Evaluation

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ChemInform Abstract: Computer-Based Drug Design, Synthesis and Biological Evaluation of New Pyrimidinone Derivatives Linked to Arylpiperazine and 2′-Carbethoxy-biphenylmethyl Moieties as α1-Adrenoceptor Antagonists and Angiotensin II AT1 Receptor Antagoni

ChemInform ◽

10.1002/chin.201109171 ◽

2011 ◽

Vol 42 (9) ◽

pp. no-no

Author(s):

M. A. H. Ismail ◽

D. A. Abou El Ella ◽

K. A. M. Abouzid ◽

G. H. A. Al-Ansary

Keyword(s):

Angiotensin Ii ◽

Drug Design ◽

Biological Evaluation ◽

At1 Receptor ◽

Design Synthesis ◽

Computer Based ◽

Synthesis And Biological Evaluation

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Thioether benzenesulfonamide inhibitors of carbonic anhydrases II and IV: Structure-based drug design, synthesis, and biological evaluation

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2010.03.014 ◽

2010 ◽

Vol 18 (9) ◽

pp. 3307-3319 ◽

Cited By ~ 27

Author(s):

William Vernier ◽

Wesley Chong ◽

David Rewolinski ◽

Samantha Greasley ◽

Thomas Pauly ◽

...

Keyword(s):

Drug Design ◽

Biological Evaluation ◽

Carbonic Anhydrases ◽

Structure Based Drug Design ◽

Design Synthesis ◽

Synthesis And Biological Evaluation

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