scholarly journals Potential Role of Olive Oil Phenolic Compounds in the Prevention of Neurodegenerative Diseases

Molecules ◽  
2015 ◽  
Vol 20 (3) ◽  
pp. 4655-4680 ◽  
Author(s):  
Jose Rodríguez-Morató ◽  
Laura Xicota ◽  
Montse Fitó ◽  
Magí Farré ◽  
Mara Dierssen ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Neurodegenerative Diseases ◽  
Olive Oil ◽  
Potential Role

The potential role of olive oil-derived MUFA in insulin sensitivity

2007 ◽  
Vol 51 (10) ◽  
pp. 1235-1248 ◽  
Author(s):  
Audrey C. Tierney ◽  
Helen M. Roche
Keyword(s):  
Insulin Sensitivity ◽  
Olive Oil ◽  
Potential Role

scholarly journals Retinal microvascular network alterations: potential biomarkers of cerebrovascular and neural diseases

2017 ◽  
Vol 312 (2) ◽  
pp. H201-H212 ◽  
Author(s):  
Delia Cabrera DeBuc ◽  
Gabor Mark Somfai ◽  
Akos Koller
Keyword(s):  
Neurodegenerative Diseases ◽  
Potential Role ◽  
Risk Identification ◽  
Imaging Biomarkers ◽  
Microvascular Network ◽  
Brain Microvessels ◽  
Retinal Microcirculation ◽  
Neural Diseases ◽  
Microvascular Imaging

Increasing evidence suggests that the conditions of retinal microvessels are indicators to a variety of cerebrovascular, neurodegenerative, psychiatric, and developmental diseases. Thus noninvasive visualization of the human retinal microcirculation offers an exceptional opportunity for the investigation of not only the retinal but also cerebral microvasculature. In this review, we show how the conditions of the retinal microvessels could be used to assess the conditions of brain microvessels because the microvascular network of the retina and brain share, in many aspects, standard features in development, morphology, function, and pathophysiology. Recent techniques and imaging modalities, such as optical coherence tomography (OCT), allow more precise visualization of various layers of the retina and its microcirculation, providing a “microscope” to brain microvessels. We also review the potential role of retinal microvessels in the risk identification of cerebrovascular and neurodegenerative diseases. The association between vision problems and cerebrovascular and neurodegenerative diseases, as well as the possible role of retinal microvascular imaging biomarkers in cerebrovascular and neurodegenerative screening, their potentials, and limitations, are also discussed.

scholarly journals Mitophagy Regulates Neurodegenerative Diseases

Cells ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 1876
Author(s):  
Xufeng Cen ◽  
Manke Zhang ◽  
Mengxin Zhou ◽  
Lingzhi Ye ◽  
Hongguang Xia
Keyword(s):  
Neurodegenerative Diseases ◽  
Signaling Pathways ◽  
Neurodegenerative Disorders ◽  
Essential Role ◽  
Molecular Mechanisms ◽  
Potential Role ◽  
Treatment Strategies ◽  
Metabolic Process ◽  
Recent Advances

Mitochondria play an essential role in supplying energy for the health and survival of neurons. Mitophagy is a metabolic process that removes dysfunctional or redundant mitochondria. This process preserves mitochondrial health. However, defective mitophagy triggers the accumulation of damaged mitochondria, causing major neurodegenerative disorders. This review introduces molecular mechanisms and signaling pathways behind mitophagy regulation. Furthermore, we focus on the recent advances in understanding the potential role of mitophagy in the pathogenesis of major neurodegenerative diseases (Parkinson’s, Alzheimer’s, Huntington’s, etc.) and aging. The findings will help identify the potential interventions of mitophagy regulation and treatment strategies of neurodegenerative diseases.

scholarly journals The potential role of phenolic compounds on modulating gut microbiota in obesity

2020 ◽  
Vol 28 (2) ◽  
pp. 195-205
Author(s):  
Gow-Chin Yen ◽  
Hsin-Lin Cheng ◽  
Li-Yu Lin ◽  
Chin Lin Hsu
Keyword(s):  
Phenolic Compounds ◽  
Gut Microbiota ◽  
Potential Role
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