scholarly journals Extrusion-Based 3D Printing of Microfluidic Devices for Chemical and Biomedical Applications: A Topical Review

Micromachines ◽  
2018 ◽  
Vol 9 (8) ◽  
pp. 374 ◽  
Author(s):  
Daniela Pranzo ◽  
Piero Larizza ◽  
Daniel Filippini ◽  
Gianluca Percoco

One of the most widespread additive manufacturing (AM) technologies is fused deposition modelling (FDM), also known as fused filament fabrication (FFF) or extrusion-based AM. The main reasons for its success are low costs, very simple machine structure, and a wide variety of available materials. However, one of the main limitations of the process is its accuracy and finishing. In spite of this, FDM is finding more and more applications, including in the world of micro-components. In this world, one of the most interesting topics is represented by microfluidic reactors for chemical and biomedical applications. The present review focusses on this research topic from a process point of view, describing at first the platforms and materials and then deepening the most relevant applications.

2016 ◽  
Vol 22 (1) ◽  
pp. 123-143 ◽  
Author(s):  
Sunpreet Singh ◽  
Rupinder Singh

Purpose – This paper aims to review the industrial and biomedical applications of state-of-the-art fused deposition modelling (FDM)-assisted investment casting (FDMAIC). Brief literature survey of methodologies, ideas, techniques and approaches used by various researchers is highlighted and use of hybrid feedstock filament-based pattern to produce metal matrix composite is duly discussed. Design/methodology/approach – Pattern replica required for investment casting (IC) of biomedical implant, machine parts, dentistry and other industrial components can be directly produced by using FDM process is presented. Relevant studies and examples explaining the suitability of FDMAIC for various applications are also presented. Findings – Researches to optimize the conventional IC with FDM solutions and develop new hybrid feedstock filament of FDM done by researchers worldwide are also discussed. The review highlights the benefit of FDMAIC to surgeons, engineers and manufacturing organizations. Research limitations/implications – The research related to this survey is limited to the suitability and applicability of FDMAIC. Originality/value – This review presents the information regarding potential IC application, which facilitates the society, engineers and manufacturing organizations by providing variety of components for assisting FDM. The information reported in this paper will serve doctors, researchers, organizations and academicians to explore the new options in the field of FDMAIC.


Author(s):  
Zicheng Zhu ◽  
Vimal Dhokia ◽  
Stephen T Newman

The manufacture of highly complex and accurate part geometries with reduced costs has led to the emergence of hybrid manufacturing technologies where varied manufacturing operations are carried out in either parallel or serial manner. One such hybrid process being currently developed is the iAtractive process, which combines additive (i.e. fused filament fabrication, which is sometimes called fused deposition modelling. However, the latter term is trademarked by Stratasys Inc. and cannot be used publicly without authorisation from Stratasys) and subtractive (i.e. computer numerical control machining) processes. In the iAtractive process production, operation sequencing of additive and subtractive operations is essential. This requires accurate estimation of production time, in which the fused filament fabrication build time is the determining factor. There have been some estimators developed for fused deposition modelling. However, these estimators are not applicable to hybrid manufacturing, particularly in process planning, which is a vital stage. This article addresses the characteristics of fused filament fabrication technologies and develops a novel and rigorous method for predicting build times. An analytical model was first created to theoretically analyse the factors that affect the part build time and was subsequently used to facilitate the design of test parts and experiments. The experimental results indicate that part volume, interaction of volume and porosity and interaction of height and intermittent factor have significant effects on build times. Finally, the estimation algorithm has been developed, which was subsequently evaluated and validated by applying a wide range of identified influential factors. The major advantage of the new proposed algorithm is its ability to estimate the build time based on simple geometrical parameters of a given part. The key factors that drive the algorithm can be directly obtained from part dimensions/drawings, providing an efficient and accurate way for fused filament fabrication time estimation. Test part evaluations and analysis have clearly demonstrated that estimation errors range from 0.1% to 13.5%, showing the validity, capability and significance of the developed algorithm and its applications to hybrid manufacture.


2020 ◽  
Vol 29 ◽  
pp. 228-232 ◽  
Author(s):  
N.A.S. Mohd Pu'ad ◽  
R.H. Abdul Haq ◽  
H. Mohd Noh ◽  
H.Z. Abdullah ◽  
M.I. Idris ◽  
...  

Author(s):  
Sunpreet Singh ◽  
Rupinder Singh

Investment casting process is known to its capability of producing clear net shape, high-dimensional accuracy and intricate design. Consistent research effort has been made by various researchers with an objective to explore the world of investment casting. Literature review revealed the effect of processing parameters on output parameters of cast specimen. This article highlights the advancements made and proposed at each step of investment casting and its hybridization with other process. Besides, investment casting has always been known to manufacture parts such as weapons, jewellery item, idols and statues of god and goddess since 3000 BC; this article reviews the present applications and trends in combination of rapid prototyping technique as integrated investment casting to serve in medical science. Advancements in shell moulding with incorporation of fibre and polymer, development of alternative feedstock filament to fused deposition modelling are duly discussed. The aim of this review article is to present state of art review of investment casting since 3200 BC. This article is organized as follows: in section ‘Introduction’, introduction to investment casting steps is given along with researches undertaken at each step; in section ‘Rapid prototyping technique’, background is given on the concept of rapid prototyping technique by examining the various approaches taken in the literature for defining rapid prototyping technique; section ‘Biomedical applications of RPT’ presents the medicine or biomedical applications of investment casting and rapid prototyping technique; section ‘Future trends’ provides some perspectives on future research and section ‘Conclusion’ closes the article by offering conclusions.


2017 ◽  
Vol 887 ◽  
pp. 128-132 ◽  
Author(s):  
Shaheryar Atta Khan ◽  
Bilal Ahmed Siddiqui ◽  
Muhammad Fahad ◽  
Maqsood Ahmed Khan

Additive manufacturing has stepped down from the world of Sci-Fi into reality. Since its conception in the 1980s the technology has come a long way. May variants of the technology are now available to the consumer. With the advent of custom built (open source) Fused Deposition Modeling based printing technology Fused Filament Fabrication (FFF), FDM/FFF has become the most used Additive Manufacturing technology. The effects of the different infill patterns of FDM/FFF on the mechanical properties of a specimen made from ABS are studied in this paper. It is shown that due to changes in internal structures, the tensile strength of the specimen changes. The study also investigate the effect of infill pattern on the build time of the specimen. Extensive testing yielded the optimal infill pattern for FDM/FFF. An open source Arduino based RepRap printer was used for the preparation of specimen and showed promising results for rapid prototyping of custom built parts to bear high loads. The study can help with the increase in the use of additive manufacturing for the manufacturing of mechanically functioning parts such as prosthetics


Abstract. Ultrasonic waves, either bulk waves or guided waves, are commonly used for non-destructive evaluation, for example in structural health monitoring. Traditional sensors for detecting ultrasonic waves include metallic strain gauges and piezoelectric ceramics. Recently piezoresistive nanocomposites have emerged as a promising sensor with high sensing range. In this paper, a constriction-resistive based sensor made from a graphene reinforced PLA filament is developed using a fused deposition modelling 3D printing approach as a novel type of ultrasonic sensor for structural health monitoring purposes. The sensor is made of very low-cost and recyclable thermoplastic material, which is lightweight and can be either directly printed onto the surface of various engineering structures, or embedded into the interior of a structure via fused filament fabrication 3D printing. These characteristics make this sensor a promising candidate compared to the traditional sensors in detecting ultrasonic waves for structural health monitoring. The printed sensors can detect ultrasonic signals with frequencies around 200 kHz, with good signal-to-noise ratio and sensitivity. When deployed between two adjacent printed tracks , and exploiting a novel kissing-bond mechanism, the sensor is capable of detecting ultrasonic waves. Several confirmatory experiments were carried out on this printed sensor to validate the capability of the printed sensor for structural health monitoring.


2019 ◽  
Vol XXII (1) ◽  
pp. 261-268
Author(s):  
Vasilescu M. D.

The scope of this research is to analyse the economic aspects of the 3D printing parts for making parts and functional sub-assemblies for different machinery. The author intends in this work to make a clarification on the economic approaches of processing FDM (Fused Deposition Modelling) and DLP (Digital Light Processing) materials which can be used for generating mechanically required items. The paper it is structured in 5 chapters. In the first chapter, there is an ordering of the materials based on the literature, but also from its own experience in generating parts by 3D printing. Synthesis is made both in terms of physical and mechanical properties, but also from the point of view of economic as well. It should be shown that the comparison will also be made from the point of view of 3D printing generation since two different printing processes are used both as the principle of generation and the way of obtaining the 3D parts. For generating, two printers will be used, which both constructively and functionally will be analysed, both as functionality and as component design possibilities. The second chapter affected to the ordering of technological parameters of 3D generation by printing the parts with defining the main technical parameters of generation of the parts. This step is important both to ensure the assembly conditions of the components, but also to the fact that the materials used to make the parts produce different comportment after the three directions in terms of contractions and the variation of the dimensions. The third chapter analyses the main ways of generating the parts with the presentation of some of the domain-specific elements generated by 3D printing with FDM and DLP. In the fourth chapter is presented the economic calculation program made with practical applications related to the parts generated in the previous chapter. The last chapter is allocated to the conclusions and comparisons from the technologicaleconomical point of view compared to other specific technologies for generating the analysed parts.


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