scholarly journals Challenges and Opportunities of Centrifugal Microfluidics for Extreme Point-of-Care Testing

Micromachines ◽  
2016 ◽  
Vol 7 (2) ◽  
pp. 32 ◽  
Author(s):  
Issac Michael ◽  
Tae-Hyeong Kim ◽  
Vijaya Sunkara ◽  
Yoon-Kyoung Cho
Keyword(s):  
Extreme Point ◽  
Point Of Care ◽  
Centrifugal Microfluidics ◽  
Point Of Care Testing ◽  
Challenges And Opportunities

scholarly journals Point-of-care testing with high-sensitivity cardiac troponin assays: the challenges and opportunities

2022 ◽  
pp. emermed-2021-211907
Author(s):  
Louise Cullen ◽  
Paul O Collinson ◽  
Evangelos Giannitsis
Keyword(s):  
Acute Coronary Syndrome ◽  
Clinical Practice ◽  
Cardiac Troponin ◽  
Point Of Care ◽  
High Sensitivity ◽  
Point Of Care Testing ◽  
Coronary Syndrome ◽  
Low Concentrations ◽  
Challenges And Opportunities ◽  
Assessment Strategies

Methods to improve the safety, accuracy and efficiency of assessment of patients with suspected acute coronary symptoms have occupied decades of study and have supported significant changes in clinical practice. Much of the progress is reliant on results of laboratory-based high-sensitivity cardiac troponin assays that can detect low concentrations with high precision. Until recently, point-of-care (POC) platforms were unable to perform with similar analytical precision as laboratory-based assays, and recommendations for their use in accelerated assessment strategies for patients with suspected acute coronary syndrome has been limited. As POC assays can provide troponin results within 20 min, and can be used proximate to patient care, improvements in the efficiency of assessment of patients with suspected acute coronary syndrome is possible, particularly with new high-sensitivity assays.

Magnetic Digital Microfluidics for Point-of-Care Testing: Where Are We Now?

2020 ◽  
Vol 27 ◽  
Author(s):  
Yi Zhang
Keyword(s):  
System Integration ◽  
Diagnostic Tests ◽  
Point Of Care ◽  
Digital Microfluidics ◽  
Controlled Environment ◽  
Point Of Care Testing ◽  
Microfluidic Platforms ◽  
Interface System ◽  
Technical Issues ◽  
Sample System

: Point-of-care (POC) testing decentralizes the diagnostic tests to the sites near the patient. Many POC tests rely microfluidic platforms for sample-to-answer analysis. Compared to other microfluidic systems, magnetic digital microfluidics demonstrate compelling advantages for POC diagnostics. In this review, we have examined the capability of magnetic digital microfluidics-based POC diagnostic platforms. More importantly, we have categorized POC settings into three classes based on “where is the point”, “who to care” and “how to test”, and evaluated the suitability of magnetic digital microfluidics in various POC settings. Furthermore, we have addressed other technical issues associated with POC testing such as controlled environment, sample-system interface, system integration and information connectivity. We hope this review would provide a guideline for the future development of magnetic digital microfluidics-based platforms for POC testing.

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