scholarly journals A New Electrochemical Platform for Dasatinib Anticancer Drug Sensing Using Fe3O4-SWCNTs/Ionic Liquid Paste Sensor

Micromachines ◽  
2021 ◽  
Vol 12 (4) ◽  
pp. 437
Author(s):  
Ali Moghaddam ◽  
Hassan Ali Zamani ◽  
Hassan Karimi-Maleh
Keyword(s):  
Optimal Condition ◽  
Anticancer Drug ◽  
Dynamic Range ◽  
Oxidation Potential ◽  
Analytical Tool ◽  
Electrochemical Investigation ◽  
Linear Dynamic Range ◽  
Linear Dynamic ◽  
Oxidation Current ◽  
Paste Electrode

A new electrochemical platform was suggested for the sensing of the dasatinib (DA) anticancer drug based on paste electrode modification (PE) amplified with Fe3O4-SWCNTs nanocomposite and 1-hexyl-3-methylimidazolium tetrafluoroborate (mim-BF4−). The new platform showed a linear dynamic range from 0.001–220 µM with a detection limit of 0.7 nM to determine DA at optimal condition. Electrochemical investigation showed that the redox reaction of DA is relative to changing the pH of solution. Moreover, Fe3O4-SWCNTs/mim-BF4−/PE has improved the oxidation current of DA about 5.58 times which reduced its oxidation potential by about 120 mV at optimal condition. In the final step, Fe3O4-SWCNTs/mim-BF4−/PE was used as an analytical platform to determine the DA in tablets and a dextrose saline spike sample, and the results showed recovery data 99.58–103.6% which confirm the powerful ability of the sensor as an analytical tool to determine the DA in real samples.

A New Nanostructure Square Wave Voltammetric Platform for Determination of Tert-butylhydroxyanisole in Food Samples

2019 ◽  
Vol 15 (2) ◽  
pp. 172-176 ◽  
Author(s):  
Fatemeh Karimi ◽  
Majede Bijad ◽  
Mohammad Farsi ◽  
Amir Vahid ◽  
Hesam Asari-Bami ◽  
...  
Keyword(s):  
Dynamic Range ◽  
Food Samples ◽  
Linear Dynamic Range ◽  
Carbon Paste ◽  
Square Wave ◽  
Linear Dynamic ◽  
Electro Oxidation ◽  
Paste Electrode

Background: Antioxidants are one of the important additives in food samples due to their role in protecting human cells against the effects of free radicals. The analysis of antioxidants is essential due to the role of antioxidants in improving body health. Objective: A square wave voltammetric sensor was fabricated for the determination of tert-butylhydroxyanisole (TBHA) based on the application of CdO/SWCNTs and 1-methyl-3-butylimidazolium chloride as mediators for the modification of carbon paste electrode (MBCl/CdO/SWCNTs/CPE). The MBCl/CdO/SWCNTs/CPE improved the sensitivity of TBHA ~ 6.7 times and showed a linear dynamic range 0.07-600 µM with detection limit 0.02 µA for the analysis of TBHA. The pH investigation confirmed that electro-oxidation of TBHA occurred by exchanging two electrons and two protons. In addition, the MBCl/CdO/SWCNTs/CPE was used for determination of TBHA in food samples.

scholarly journals First Report for Determination of d-Penicillamine in the Presence of Tryptophan Using a 2-Chlorobenzoyl Ferrocene/Ag-Supported ZnO Nanoplate–Modified Carbon Paste Electrode

2018 ◽  
Vol 101 (1) ◽  
pp. 208-215 ◽  
Author(s):  
Hadi Beitollahi ◽  
Abbas Gholami ◽  
Mohammad Reza Ganjali
Keyword(s):  
Carbon Paste Electrode ◽  
High Selectivity ◽  
Dynamic Range ◽  
Modified Carbon Paste Electrode ◽  
Linear Dynamic Range ◽  
Carbon Paste ◽  
Linear Dynamic ◽  
Wide Linear Dynamic Range ◽  
Paste Electrode

Abstract In this work, a carbon paste electrode modified with Ag-ZnO nanoplates and 2-chlorobenzoyl ferrocene was prepared and applied for the determination of d-penicillamine in the presence of tryptophan. The morphologies of Ag-ZnO nanoplates were examined by scanning electron microscopy. It was found that under an optimum condition (pH 7.0), the oxidation of d-penicillamine at the surface of such an electrode occurs at a potential about 165 mV less positive than that of an unmodified carbon paste electrode. The diffusion coefficient (D = 7.6 × 10−6 cm2/s) and the electron transfer coefficient (α = 0.54) for d-penicillamine oxidation were also determined. The proposed method exhibited a wide linear dynamic range of 0.03–250.0 µM, with an LOD (S/N = 3) of 0.015 µM. Moreover, the modified electrode exhibited good reproducibility and high selectivity, demonstrating its feasibility for the analytical purpose. Lastly, this new sensor was used for the determination of d-penicillamine and tryptophan in real samples.

Convenient Fiber-Optic-Based Sample Cell for Shpol'skii and Low-Temperature Phosphorescence Spectrometry

1989 ◽  
Vol 43 (3) ◽  
pp. 422-425 ◽  
Author(s):  
Richard T. Madison ◽  
Mary K. Carroll ◽  
Gary M. Hieftje
Keyword(s):  
Low Temperature ◽  
Fiber Optic ◽  
Dynamic Range ◽  
Detection Limits ◽  
Linear Dynamic Range ◽  
Sample Cell ◽  
Linear Dynamic ◽  
Light Guides

A sample cell for observing the Shpol'skii effect at 77 K is described and analytically assessed. The cell employs fiber-optic light guides to transport excitation and emission radiation. The system is compact, inexpensive, and simple to construct from commercially available laboratory components, and it alleviates several problems inherent in conventional refrigerated-cell designs. Detection limits for anthracene, coronene, and pyrene obtained with the sample cell are 8.8 × 10−8 M, 8.4 × 10−7 M, and 3.5 × 10−7 M, respectively. The linear dynamic range for each compound is 2 to 3 orders of magnitude.

scholarly journals Single particle inductively coupled plasma mass spectrometry: investigating nonlinear response observed in pulse counting mode and extending the linear dynamic range by compensating for dead time related count losses on a microsecond timescale

2020 ◽  
Vol 35 (1) ◽  
pp. 84-99 ◽  
Author(s):  
Ingo Strenge ◽  
Carsten Engelhard
Keyword(s):  
Inductively Coupled Plasma ◽  
Nonlinear Response ◽  
Dynamic Range ◽  
Dead Time ◽  
Linear Dynamic Range ◽  
Pulse Counting ◽  
Inductively Coupled ◽  
Linear Dynamic ◽  
Order Of Magnitude ◽  
Plasma Mass Spectrometry

Sampling of the pulse-counting signal with μs time-resolution provided a functional compensation for dead-time related count losses in spICP-MS, ultimately improving the linear dynamic range by one order of magnitude towards higher count rates.

A study on the quick measuring method of linear dynamic range of receiver

Measurement ◽  
2015 ◽  
Vol 59 ◽  
pp. 237-240 ◽  
Author(s):  
Jinbao Yao ◽  
Baoping Tang ◽  
Jie Zhao
Keyword(s):  
Dynamic Range ◽  
Measuring Method ◽  
Linear Dynamic Range ◽  
Linear Dynamic
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