scholarly journals Micro-Fabrication of Components for a High-Density Sub-Retinal Visual Prosthesis

Micromachines ◽  
2020 ◽  
Vol 11 (10) ◽  
pp. 944 ◽  
Author(s):  
Douglas Shire ◽  
Marcus Gingerich ◽  
Patricia Wong ◽  
Michael Skvarla ◽  
Stuart Cogan ◽  
...  
Keyword(s):  
High Density ◽  
Visual Prosthesis ◽  
Massachusetts Institute Of Technology ◽  
Electrode Arrays ◽  
Retinal Implant ◽  
Micro Fabrication ◽  
Bionic Eye ◽  
Startup Company ◽  
Problems And Solutions ◽  
Institute Of Technology

We present a retrospective of unique micro-fabrication problems and solutions that were encountered through over 10 years of retinal prosthesis product development, first for the Boston Retinal Implant Project initiated at the Massachusetts Institute of Technology and at Harvard Medical School’s teaching hospital, the Massachusetts Eye and Ear—and later at the startup company Bionic Eye Technologies, by some of the same personnel. These efforts culminated in the fabrication and assembly of 256+ channel visual prosthesis devices having flexible multi-electrode arrays that were successfully implanted sub-retinally in mini-pig animal models as part of our pre-clinical testing program. We report on the processing of the flexible multi-layered, planar and penetrating high-density electrode arrays, surgical tools for sub-retinal implantation, and other parts such as coil supports that facilitated the implantation of the peri-ocular device components. We begin with an overview of the implantable portion of our visual prosthesis system design, and describe in detail the micro-fabrication methods for creating the parts of our system that were assembled outside of our hermetically-sealed electronics package. We also note the unique surgical challenges that sub-retinal implantation of our micro-fabricated components presented, and how some of those issues were addressed through design, materials selection, and fabrication approaches.

Applying the Anderson-Darling Test to Suicide Clusters

Crisis ◽  
2013 ◽  
Vol 34 (6) ◽  
pp. 434-437 ◽  
Author(s):  
Donald W. MacKenzie
Keyword(s):  
Poisson Process ◽  
Goodness Of Fit ◽  
Small Samples ◽  
Massachusetts Institute Of Technology ◽  
Homogeneous Poisson Process ◽  
Cornell University ◽  
The Difference ◽  
Suicide Clusters ◽  
Institute Of Technology ◽  
Anderson Darling

Background: Suicide clusters at Cornell University and the Massachusetts Institute of Technology (MIT) prompted popular and expert speculation of suicide contagion. However, some clustering is to be expected in any random process. Aim: This work tested whether suicide clusters at these two universities differed significantly from those expected under a homogeneous Poisson process, in which suicides occur randomly and independently of one another. Method: Suicide dates were collected for MIT and Cornell for 1990–2012. The Anderson-Darling statistic was used to test the goodness-of-fit of the intervals between suicides to distribution expected under the Poisson process. Results: Suicides at MIT were consistent with the homogeneous Poisson process, while those at Cornell showed clustering inconsistent with such a process (p = .05). Conclusions: The Anderson-Darling test provides a statistically powerful means to identify suicide clustering in small samples. Practitioners can use this method to test for clustering in relevant communities. The difference in clustering behavior between the two institutions suggests that more institutions should be studied to determine the prevalence of suicide clustering in universities and its causes.

Editorial: Advancing the Debate on Architecture, Planning, and Built Environment Research

2015 ◽  
Vol 9 (2) ◽  
Author(s):  
Ashraf M. Salama
Keyword(s):  
Learning Styles ◽  
Cultural Values ◽  
Urban Studies ◽  
Wide Spectrum ◽  
Journal Ranking ◽  
Massachusetts Institute Of Technology ◽  
Open Access Journals ◽  
Practice Based Research ◽  
Institute Of Technology ◽  
Number Of Citations

With an acceptance rate that does not exceed 25% of the total papers and articles submitted to the journal, IJAR – International Journal of Architectural Research is moving forward to position itself among the leading journals in architecture and urban studies worldwide. As this is the case since the beginning of volume 5, issue 1, March 2011, one must note that the journal has been covered by several data and index bases since its inception including Avery Index to Architectural Periodicals, EBSCO-Current Abstracts-Art and Architecture, INTUTE, Directory of Open Access Journals, Pro-Quest, Scopus-Elsevier and many university library databases across the globe. This is coupled with IJAR being an integral part of the archives and a featured collection of ArchNet and the Aga Khan Documentation Centre at MIT: Massachusetts Institute of Technology, Cambridge, MA.In 2014, IJAR was included in Quartile 2 / Q2 list of Journals both in ‘Architecture’ and ‘Urban Studies.’ As of May 2015, IJAR is ranked 23 out of 83 journals in ‘Architecture’ and 59 out of 119 in ‘Urban Studies.’ Rankings are based on the SJR (SCImago Journal Ranking); an Elsevier- SCOPUS indicator that measures the scientific influence of the average article in a journal. SJR is a measure of scientific influence of scholarly journals that accounts for both the number of citations received by a journal and the importance or prestige of the journals where such citations come from. See here for more information (http://www.scimagojr.com/index.php) and (http://www.journalmetrics.com/sjr.php). While the journal is now on top of many of the distinguished journals in Elsevier- SCOPUS database, we will keep aspiring to sustain our position and move forward to Q1 group list and eventually in the top 10 journal list in the field. However, this requires sustained efforts and conscious endeavours that give attention to quality submissions through a rigorous review process. This edition of IJAR: volume 9, issue 2, July 2015 includes debates on a wide spectrum of issues, explorations and investigations in various settings. The issue encompasses sixteen papers addressing cities, settlements, and projects in Europe, South East Asia, and the Middle East. Papers involve international collaborations evidenced by joint contributions and come from scholars in universities, academic institutions, and practices in Belgium; Egypt; Greece; Italy; Jordan; Malaysia; Palestine; Qatar; Saudi Arabia; Serbia; Spain; Turkey; and the United Kingdom. In this editorial I briefly outline the key issues presented in these papers, which include topics relevant to social housing, multigenerational dwelling, practice-based research, sustainable design and biomimetic models, learning environments and learning styles, realism and the post modern condition, development and planning, urban identity, contemporary landscapes, and cultural values and traditions.

XX Rudi Dombusch, Keys to Prosperity. Free Markets, Sound Money, and bit of Luck The MIT Press 2000 Londres

2009 ◽  
Vol 33 (130) ◽  
Author(s):  
GERARDO REYES GUZMÁN
Keyword(s):  
Massachusetts Institute ◽  
Massachusetts Institute Of Technology ◽  
Free Markets ◽  
Institute Of Technology

Rudiger Dornbusch, destacado economista del Massachusetts Institute of Technology (MIT), analiza en esta trascendental obra tópicos como inflación, deuda, tipos de cambio, política externa y mercados emergentes. El marco conceptual descansa en la corriente de la escuela de Chicago, la cual parte del principio de que el mercado es el mecanismo que garantiza la creación del progreso en contraste con el Estado, que en su afán por encontrar soluciones perfectas, fracasa regularmente en sus cometidos.

Life sciences intellectual property licensing at the Massachusetts Institute of Technology

2021 ◽  
Vol 39 (3) ◽  
pp. 293-301
Author(s):  
Samuel Huang ◽  
Kien Wei Siah ◽  
Detelina Vasileva ◽  
Shirley Chen ◽  
Lita Nelsen ◽  
...  
Keyword(s):  
Intellectual Property ◽  
Life Sciences ◽  
Massachusetts Institute ◽  
Massachusetts Institute Of Technology ◽  
Institute Of Technology
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