scholarly journals Deep Hypersaline Anoxic Basins as Untapped Reservoir of Polyextremophilic Prokaryotes of Biotechnological Interest

Marine Drugs ◽  
2020 ◽  
Vol 18 (2) ◽  
pp. 91 ◽  
Author(s):  
Stefano Varrella ◽  
Michael Tangherlini ◽  
Cinzia Corinaldesi
Keyword(s):  
New Species ◽  
Secondary Metabolites ◽  
Deep Sea ◽  
Current Knowledge ◽  
Strong Impact ◽  
Biotechnological Applications ◽  
Prokaryotic Diversity ◽  
Anoxic Basins ◽  
Isolated Species

Deep-sea hypersaline anoxic basins (DHABs) are considered to be among the most extreme ecosystems on our planet, allowing only the life of polyextremophilic organisms. DHABs’ prokaryotes exhibit extraordinary metabolic capabilities, representing a hot topic for microbiologists and biotechnologists. These are a source of enzymes and new secondary metabolites with valuable applications in different biotechnological fields. Here, we review the current knowledge on prokaryotic diversity in DHABs, highlighting the biotechnological applications of identified taxa and isolated species. The discovery of new species and molecules from these ecosystems is expanding our understanding of life limits and is expected to have a strong impact on biotechnological applications.

scholarly journals Marine Fungi: Biotechnological Perspectives from Deep-Hypersaline Anoxic Basins

Diversity ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 113 ◽  
Author(s):  
Barone ◽  
Varrella ◽  
Tangherlini ◽  
Rastelli ◽  
Dell'Anno ◽  
...  
Keyword(s):  
New Species ◽  
Deep Sea ◽  
Marine Fungi ◽  
Bioactive Molecules ◽  
Microbial Biodiversity ◽  
Biotechnological Potential ◽  
Anoxic Basins ◽  
Hostile Environments ◽  
Halophilic Species ◽  
Relevant Component

Deep-sea hypersaline anoxic basins (DHABs) are one of the most hostile environments on Earth. Even though DHABs have hypersaline conditions, anoxia and high hydrostatic pressure, they host incredible microbial biodiversity. Among eukaryotes inhabiting these systems, recent studies demonstrated that fungi are a quantitatively relevant component. Here, fungi can benefit from the accumulation of large amounts of organic material. Marine fungi are also known to produce bioactive molecules. In particular, halophilic and halotolerant fungi are a reservoir of enzymes and secondary metabolites with valuable applications in industrial, pharmaceutical, and environmental biotechnology. Here we report that among the fungal taxa identified from the Mediterranean and Red Sea DHABs, halotolerant halophilic species belonging to the genera Aspergillus and Penicillium can be used or screened for enzymes and bioactive molecules. Fungi living in DHABs can extend our knowledge about the limits of life, and the discovery of new species and molecules from these environments can have high biotechnological potential.

scholarly journals Chemical Elicitors Induce Rare Bioactive Secondary Metabolites in Deep-Sea Bacteria under Laboratory Conditions

Metabolites ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 107
Author(s):  
Rafael de Felício ◽  
Patricia Ballone ◽  
Cristina Freitas Bazzano ◽  
Luiz F. G. Alves ◽  
Renata Sigrist ◽  
...  
Keyword(s):  
Natural Products ◽  
Secondary Metabolites ◽  
Natural Product ◽  
Deep Sea ◽  
Chemical Space ◽  
Bacterial Genome ◽  
Vast Number ◽  
Bacterial Metabolites ◽  
Laboratory Conditions ◽  
Deep Sea Bacteria

Bacterial genome sequencing has revealed a vast number of novel biosynthetic gene clusters (BGC) with potential to produce bioactive natural products. However, the biosynthesis of secondary metabolites by bacteria is often silenced under laboratory conditions, limiting the controlled expression of natural products. Here we describe an integrated methodology for the construction and screening of an elicited and pre-fractionated library of marine bacteria. In this pilot study, chemical elicitors were evaluated to mimic the natural environment and to induce the expression of cryptic BGCs in deep-sea bacteria. By integrating high-resolution untargeted metabolomics with cheminformatics analyses, it was possible to visualize, mine, identify and map the chemical and biological space of the elicited bacterial metabolites. The results show that elicited bacterial metabolites correspond to ~45% of the compounds produced under laboratory conditions. In addition, the elicited chemical space is novel (~70% of the elicited compounds) or concentrated in the chemical space of drugs. Fractionation of the crude extracts further evidenced minor compounds (~90% of the collection) and the detection of biological activity. This pilot work pinpoints strategies for constructing and evaluating chemically diverse bacterial natural product libraries towards the identification of novel bacterial metabolites in natural product-based drug discovery pipelines.

scholarly journals Loose Ends in the Cortinarius Phylogeny: Five New Myxotelamonoid Species Indicate a High Diversity of These Ectomycorrhizal Fungi with South American Nothofagaceae

Life ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 420
Author(s):  
María Eugenia Salgado Salomón ◽  
Carolina Barroetaveña ◽  
Tuula Niskanen ◽  
Kare Liimatainen ◽  
Matthew E. Smith ◽  
...  
Keyword(s):  
New Species ◽  
Current Knowledge ◽  
Phylogenetic Analyses ◽  
Molecular Data ◽  
Global Scale ◽  
South American ◽  
Edible Fungi ◽  
Rdna Its ◽  
Morphological And Molecular Data ◽  
High Diversity

This paper is a contribution to the current knowledge of taxonomy, ecology and distribution of South American Cortinarius (Pers.) Gray. Cortinarius is among the most widely distributed and species-rich basidiomycete genera occurring with South American Nothofagaceae and species are found in many distinct habitats, including shrublands and forests. Due to their ectomycorrhizal role, Cortinarius species are critical for nutrient cycling in forests, especially at higher latitudes. Some species have also been reported as edible fungi with high nutritional quality. Our aim is to unravel the taxonomy of selected Cortinarius belonging to phlegmacioid and myxotelamonioid species based on morphological and molecular data. After widely sampling Cortinarius specimens in Patagonian Nothofagaceae forests and comparing them to reference collections (including holotypes), we propose five new species of Cortinarius in this work. Phylogenetic analyses of concatenated rDNA ITS-LSU and RPB1 sequences failed to place these new species into known Cortinarius sections or lineages. These findings highlight our knowledge gaps regarding the fungal diversity of South American Nothofagaceae forests. Due to the high diversity of endemic Patagonian taxa, it is clear that the South American Cortinarius diversity needs to be discovered and described in order to understand the evolutionary history of Cortinarius on a global scale.

scholarly journals Anabaenopeptins: What We Know So Far

Toxins ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 522
Author(s):  
Patrick Romano Monteiro ◽  
Samuel Cavalcante do Amaral ◽  
Andrei Santos Siqueira ◽  
Luciana Pereira Xavier ◽  
Agenor Valadares Santos
Keyword(s):  
Secondary Metabolites ◽  
Bioactive Compounds ◽  
Inhibitory Activity ◽  
Important Class ◽  
Biotechnological Applications ◽  
Peptide Synthetases ◽  
Ecological Roles ◽  
Cyclic Hexapeptides ◽  
Key Features

Cyanobacteria are microorganisms with photosynthetic mechanisms capable of colonizing several distinct environments worldwide. They can produce a vast spectrum of bioactive compounds with different properties, resulting in an improved adaptative capacity. Their richness in secondary metabolites is related to their unique and diverse metabolic apparatus, such as Non-Ribosomal Peptide Synthetases (NRPSs). One important class of peptides produced by the non-ribosomal pathway is anabaenopeptins. These cyclic hexapeptides demonstrated inhibitory activity towards phosphatases and proteases, which could be related to their toxicity and adaptiveness against zooplankters and crustaceans. Thus, this review aims to identify key features related to anabaenopeptins, including the diversity of their structure, occurrence, the biosynthetic steps for their production, ecological roles, and biotechnological applications.

Whale falls, multiple colonisations of the deep, and the phylogeny of Hesionidae (Annelida)

2015 ◽  
Vol 29 (2) ◽  
pp. 105 ◽  
Author(s):  
Mindi Summers ◽  
Fredrik Pleijel ◽  
Greg W. Rouse
Keyword(s):  
New Species ◽  
Maximum Likelihood ◽  
16S Rrna ◽  
Deep Sea ◽  
Phylogenetic Relationships ◽  
18S Rrna ◽  
Shallow Waters ◽  
28S Rrna ◽  
Mitochondrial Cytochrome ◽  
New Members

Phylogenetic relationships within Hesionidae Grube, 1850 are assessed via maximum parsimony and maximum likelihood analyses of mitochondrial (cytochrome c oxidase subunit I and 16S rRNA) and nuclear (18S rRNA, and 28S rRNA) data. The analyses are based on 42 hesionid species; six of these being new species that are described here. The new species, all from deep (>200 m depth) benthic environments (including whale falls) in the eastern Pacific, are Gyptis shannonae, sp. nov., Neogyptis julii, sp. nov., Sirsoe sirikos, sp. nov., Vrijenhoekia ketea, sp. nov., Vrijenhoekia falenothiras, sp. nov., and Vrijenhoekia ahabi, sp. nov. The molecular divergence among the new members of Vrijenhoekia is pronounced enough to consider them cryptic species, even though we cannot distinguish among them morphologically. Our results also showed that the subfamily Hesioninae Grube, 1850, as traditionally delineated, was paraphyletic. We thus restrict Hesioninae to include only Hesionini Grube, 1850 and refer the remaining members to Psamathinae Pleijel, 1998. The present study increases the number of hesionid species associated with whale falls from one to six and markedly increases the number of described deep-sea hesionid taxa. There appear to have been multiple colonisations of the deep sea from shallow waters by hesionids, though further sampling is warranted.

A new slipper lobster of the genus Petrarctus Holthuis, 2002 (Crustacea, Decapoda, Scyllaridae) from Southwest coast of India

Zootaxa ◽  
2017 ◽  
Vol 4329 (5) ◽  
pp. 477 ◽  
Author(s):  
CHIEN-HUI YANG ◽  
APPUKUTTANNAIR BIJU KUMAR ◽  
TIN-YAM CHAN
Keyword(s):  
New Species ◽  
Deep Sea ◽  
Genetic Information ◽  
Anterior Part ◽  
Molecular Genetic ◽  
Taxonomic Status ◽  
Molecular Genetic Analysis ◽  
Andaman Sea ◽  
Abdominal Somite ◽  
A New Species

A new species of slipper lobster of the genus Petrarctus Holthuis, 2002 was discovered from southwestern India during a survey of deep sea crustaceans. The new species closely resembles P. veliger Holthuis, 2002 from the Andaman Sea and western Pacific but differs mainly in the color marking on abdominal somite I, having a relatively lower cardiac tooth but with better developed tubercles on the abdomen, as well as a differently shaped anterior part of the thoracic sternum. Molecular genetic analysis also confirms the distinct taxonomic status of the new species. To fix the identity of the type species of the genus, a neotype of P. rugosus (H. Milne Edwards, 1837) was selected from a recently collected Indian specimen with color and genetic information. 

Five new deep-sea species of nudibranchs (Gastropoda: Heterobranchia: Cladobranchia) from the Northeast Pacific

Zootaxa ◽  
2018 ◽  
Vol 4526 (4) ◽  
pp. 401 ◽  
Author(s):  
ÁNGEL VALDÉS ◽  
LONNY LUNDSTEN ◽  
NERIDA G. WILSON
Keyword(s):  
Climate Change ◽  
New Species ◽  
Deep Sea ◽  
Undescribed Species ◽  
Invertebrate Community ◽  
Nuclear Markers ◽  
Mitochondrial Coi ◽  
Northeast Pacific ◽  
Northeastern Pacific ◽  
System Information

Increased exploration of northeastern Pacific deep-sea habitats has revealed a diverse and often poorly-known invertebrate community, including a number of undescribed species of nudibranchs studied herein. We used morphology to distinguish several new species from their congeners, and generated data where possible for mitochondrial (COI, 16S) and nuclear markers (H3) to place them in a phylogenetic context. We described here Tritonia nigritigris sp. nov., Dendronotus claguei sp. nov., Ziminella vrijenhoeki sp. nov., Cuthona methana sp. nov., Aeolidia libitinaria sp. nov. and redescribed Zeusia herculea (Bergh, 1894). Another species of Tritonia is described but not named due to the absence of reproductive system information. Although there are difficulties in collection from deep-sea habitats, only two of our new species are known from single specimens. As with many other deep-sea regions, we expect the number of new species from this region to increase with further exploration. Because the deep regions of the northeast Pacific are particularly vulnerable to the effects of decreasing oxygenation due to climate change, we consider that documenting this fauna has some level of urgency. 

Two new species of Cossura (Cossuridae, Annelida) from the terminal lobes of the Congo River deep-sea fan

2017 ◽  
Vol 97 (5) ◽  
pp. 881-888
Author(s):  
Anna Zhadan
Keyword(s):  
New Species ◽  
Deep Sea ◽  
Anterior Margin ◽  
Posterior Part ◽  
Entire Body ◽  
Congo River ◽  
Two New Species ◽  
Dark Pigmentation ◽  
Sea Fan ◽  
Scanning Electron

Two new species of Cossura Webster & Benedict, 1887 were found in material collected during sampling from the terminal lobes of the Congo deep-sea fan. They were described using light and scanning electron microscopy. Cossura platypus sp. nov. has 15–17 thoracic chaetigers, a prostomium longer than it is wide, with a widely rounded anterior margin, an abruptly expanded posterior prostomial ring the same length as the peristomium, without a mid-ventral notch, a branchial filament attached to the midlength of chaetiger 3, and a pygidium with three anal cirri. Cossura platypus sp. nov. is similar to C. brunnea Fauchald, 1972 but differs in the shape of the prostomium, which is widely rounded anteriorly in C. platypus sp. nov. and is broadly triangular in C. brunnea; furthermore, C. platypus sp. nov.is uniformly pale, whereas C. brunnea has dark pigmentation. Cossura candida Hartman, 1955 differs from C. platypus sp. nov. in the conical shape of the prostomium and 24–35 thoracic chaetigers. Cossura flabelligera sp. nov. has 16–19 thoracic chaetigers, a conical prostomium, and a branchial filament arising from the posterior part of chaetiger 2; the entire body, including the chaetae, is covered by a thick mucous sheath similar to the tunic of flabelligerids. Cossura flabelligera sp. nov. resembles C. longocirrata Webster & Benedict, 1887 in the position of the branchial filament, the shape of the prostomium, and the number of thoracic chaetigers; it differs in having a thick mucous sheath. This character seems to be unique for the Cossuridae.

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