scholarly journals Calcium Silicate-Based Root Canal Sealers: A Narrative Review and Clinical Perspectives

Materials ◽  
2021 ◽  
Vol 14 (14) ◽  
pp. 3965
Author(s):  
Germain Sfeir ◽  
Carla Zogheib ◽  
Shanon Patel ◽  
Thomas Giraud ◽  
Venkateshbabu Nagendrababu ◽  
...  
Keyword(s):  
Root Canal ◽  
Calcium Silicate ◽  
Current Knowledge ◽  
Antimicrobial Properties ◽  
Narrative Review ◽  
Current Evidence ◽  
Short Term ◽  
Root Canal Sealers

Over the last two decades, calcium silicate-based materials have grown in popularity. As root canal sealers, these formulations have been extensively investigated and compared with conventional sealers, such as zinc oxide–eugenol and epoxy resin-based sealers, in in vitro studies that showed their promising properties, especially their biocompatibility, antimicrobial properties, and certain bioactivity. However, the consequence of their higher solubility is a matter of debate and still needs to be clarified, because it may affect their long-term sealing ability. Unlike conventional sealers, those sealers are hydraulic, and their setting is conditioned by the presence of humidity. Current evidence reveals that the properties of calcium silicate-based sealers vary depending on their formulation. To date, only a few short-term investigations addressed the clinical outcome of calcium silicate-based root canal sealers. Their use has been showed to be mainly based on practitioners’ clinical habits rather than manufacturers’ recommendations or available evidence. However, their particular behavior implies modifications of the clinical protocol used for conventional sealers. This narrative review aimed to discuss the properties of calcium silicate-based sealers and their clinical implications, and to propose rational indications for these sealers based on the current knowledge.

scholarly journals Właściwości alkalizujące wybranych krzemianowo-wapniowych uszczelniaczy kanałowych. Badanie in vitro

2018 ◽  
Vol 64 (4) ◽  
Author(s):  
Przemysław Reszka ◽  
Łukasz Kucharski ◽  
Adam Klimowicz ◽  
Mariusz Lipski
Keyword(s):  
Root Canal ◽  
Calcium Silicate ◽  
In Vitro Study ◽  
Root Canal Sealer ◽  
Ph Values ◽  
Water Ph ◽  
Ah Plus ◽  
Ph Level ◽  
Root Canal Sealers

ABSTRACTIntroduction: The aim of this in vitro study was to assess the pH values of selected calcium-silicate root canal sealers in comparison with AH Plus resin-based root canal sealer.Materials and methods: Six root canal sealers were included in this study: BioRoot RCS (Septodont, France), GuttaFlow bioseal (Coltėne/Whaledent, Switzerland), MTA Fillapex (Angelus, Brazil), Total Fill BC Sealer (FKG, Switzerland), Well-Root ST (Vericom, Korea) and AH Plus (Dentsply, DeTrey, Germany). Materials samples (n = 6) were placed in dishes and immersed in 10 mL of distilled water (pH = 6.8). After 1, 3, 24, 48, 72, 168, 336 and 504 hrs, water pH was determined with a pH meter calibrated with a solution of known pH. Data were statistically analyzed using Student-t test (p < 0.05).Results: There were differences in the water pH between the materials tested. The highest water pHs were exhibited by Total Fill BC Sealer, Well-Root ST and BioRoot RCS (pH ~12), followed by GuttaFlow bioseal (pH ~10.5) and MTA Fillapex (pH ~9). The lowest pH was shown by AH Plus (pH ~8).Conclusions: All calcium-silicate root canal sealers studied are able to elevate the pH level, which could have biological and antimicrobial effects. The AH Plus root canal sealer has poor alkalizing properties.

scholarly journals Physical Properties and Biofunctionalities of Bioactive Root Canal Sealers In Vitro

Nanomaterials ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1750
Author(s):  
Seung Bin Jo ◽  
Hyun Kyung Kim ◽  
Hae Nim Lee ◽  
Yu-Jin Kim ◽  
Kapil Dev Patel ◽  
...  
Keyword(s):  
Root Canal ◽  
Calcium Silicate ◽  
Biological Properties ◽  
Ion Release ◽  
Water Contact ◽  
Dimensional Changes ◽  
Sem Image ◽  
Potential Strategy ◽  
Root Canal Sealers

Calcium silicate-based bioactive glass has received significant attention for use in various biomedical applications due to its excellent bioactivity and biocompatibility. However, the bioactivity of calcium silicate nanoparticle-incorporated bioactive dental sealer is not much explored. Herein, three commercially available bioactive root canal sealers (Endoseal MTA (EDS), Well-Root ST (WST), and Nishika Canal Sealer BG (NBG)) were compared with a resin-based control sealer (AH Plus (AHP)) in terms of physical, chemical, and biological properties. EDS and NBG showed 200 to 400 nm and 100 to 200 nm nanoparticle incorporation in the SEM image, respectively, and WST and NBG showed mineral deposition in Hank’s balanced salt solution after 28 days. The flowability and film thickness of all products met the ISO 3107 standard. Water contact angle, linear dimensional changes, and calcium and silicate ion release were significantly different among groups. All bioactive root canal sealers released calcium ions, while NBG released ~10 times more silicon ions than the other bioactive root canal sealers. Under the cytocompatible extraction range, NBG showed prominent cytocompatibility, osteogenecity, and angiogenecity compared to other sealers in vitro. These results indicate that calcium silicate nanoparticle incorporation in dental sealers could be a potential strategy for dental periapical tissue regeneration.

scholarly journals Evaluation of the radiopacity of selected calcium-silicate root canal sealers

2019 ◽  
Vol 65 (4) ◽  
Author(s):  
Przemysław Reszka ◽  
Katarzyna Grocholewicz ◽  
Agnieszka Droździk ◽  
Mariusz Lipski
Keyword(s):  
Root Canal ◽  
Calcium Silicate ◽  
In Vitro Study ◽  
International Standards ◽  
Root Canal Filling ◽  
Filling Materials ◽  
Ah Plus ◽  
Root Canal Sealers

Introduction: International standards require adequate radiopacity of root canal filling materials to distinguish them from natural structures, such as tooth tissues, and to allow evaluation of the quality of the root canal filling.The aim of this in vitro study was to assess the radiopacity of selected calcium-silicate root canal sealers compared with the resin-based AH Plus root canal sealer.Materials and methods: The study included 6 root canal sealers: BioRoot RCS, GuttaFlow bioseal, MTA Fillapex, Total Fill BC Sealer, Well-Root ST and AH Plus. Six disc-shaped samples were prepared from all analysed materials (4 mm in diameter and 1 mm thick) and analysed using a digital radiography technique and aluminium step wedges (1.5–15 mm thick) as a standard reference. The radiopacity was determined using computer image analysis. The data was statistically analysed using a Tukey’s range test.Results: All root canal sealers showed radiopacity at least corresponding to the 3 mm aluminium step wedge. AH Plus (13.23 mm Al) showed the highest radiopacity, followed by Total Fill BC Sealer (7.93 mm Al), Well-Root ST (7.12 mm Al), BioRoot RCS (5.93 mm Al) and GuttaFlow bioseal (5.08 mm Al ). MTA Fillapex (3.02 mm Al) showed the lowest radiopacity.Conclusions: Although the evaluated root canal sealers show different radiopacities, all the materials met the criteria laid down by the International Organization of Standardization.

Perioperative Abstinence from Cigarettes

2006 ◽  
Vol 104 (2) ◽  
pp. 356-367 ◽  
Author(s):  
David O. Warner ◽  
David C. Warltier
Keyword(s):  
Chronic Exposure ◽  
Current Knowledge ◽  
Recovery Process ◽  
Current Evidence ◽  
Perioperative Outcomes ◽  
Short Term ◽  
Healthcare Facilities ◽  
Perioperative Morbidity ◽  
Valuable Adjunct

Chronic exposure to cigarette smoke produces profound changes in physiology that may alter responses to perioperative interventions and contribute to perioperative morbidity. Because of smoke-free policies in healthcare facilities, all smokers undergoing surgery are abstinent from cigarettes for at least some period of time so that all are in various stages of recovery from the effects of smoke. Understanding this recovery process will help perioperative physicians better treat these patients. This review examines current knowledge regarding how both short-term (duration ranging from hours to weeks) and long-term smoking cessation affects selected physiology and pathophysiology of particular relevance to perioperative outcomes and how these changes affect perioperative risk. It will also consider current evidence regarding how nicotine replacement therapy, a valuable adjunct to help patients maintain abstinence, may affect perioperative physiology.

Ultrastructural investigations of MDL 19,660-induced effects on the canine platelet and megakaryocyte

1990 ◽  
Vol 48 (3) ◽  
pp. 374-375
Author(s):  
D.E. Loudy ◽  
J. Sprinkle-Cavallo ◽  
J.T. Yarrington ◽  
F.Y. Thompson ◽  
J.P. Gibson
Keyword(s):  
Antidepressant Drug ◽  
Beagle Dogs ◽  
Long Term Effects ◽  
Short Term ◽  
Platelet Counts ◽  
Toxicological Studies ◽  
Induced Aggregation ◽  
Internal Architecture

Previous short term toxicological studies of one to two weeks duration have demonstrated that MDL 19,660 (5-(4-chlorophenyl)-2,4-dihydro-2,4-dimethyl-3Hl, 2,4-triazole-3-thione), an antidepressant drug, causes a dose-related thrombocytopenia in dogs. Platelet counts started to decline after two days of dosing with 30 mg/kg/day and continued to decrease to their lowest levels by 5-7 days. The loss in platelets was primarily of the small discoid subpopulation. In vitro studies have also indicated that MDL 19,660: does not spontaneously aggregate canine platelets and has moderate antiaggregating properties by inhibiting ADP-induced aggregation. The objectives of the present investigation of MDL 19,660 were to evaluate ultrastructurally long term effects on platelet internal architecture and changes in subpopulations of platelets and megakaryocytes.Nine male and nine female beagle dogs were divided equally into three groups and were administered orally 0, 15, or 30 mg/kg/day of MDL 19,660 for three months. Compared to a control platelet range of 353,000- 452,000/μl, a doserelated thrombocytopenia reached a maximum severity of an average of 135,000/μl for the 15 mg/kg/day dogs after two weeks and 81,000/μl for the 30 mg/kg/day dogs after one week.

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