scholarly journals High Bactericidal Self-Assembled Nano-Monolayer of Silver Sulfadiazine on Hydroxylated Material Surfaces

Materials ◽  
2019 ◽  
Vol 12 (17) ◽  
pp. 2761 ◽  
Author(s):  
Angelo Taglietti ◽  
Giacomo Dacarro ◽  
Daniele Barbieri ◽  
Lucia Cucca ◽  
Pietro Grisoli ◽  
...  
Keyword(s):  
Bacterial Adhesion ◽  
High Surface ◽  
Bactericidal Effect ◽  
Silver Sulfadiazine ◽  
Layer By Layer ◽  
Self Assembled Monolayer ◽  
Surface Mass ◽  
Material Surfaces ◽  
Functionalized Materials ◽  
Self Assembled

Anti-infective surfaces are a modern strategy to address the issue of infection related to the clinical use of materials for implants and medical devices. Nanocoatings, with their high surface/mass ratio, lend themselves to being mono-layered on the material surfaces to release antibacterial molecules and prevent bacterial adhesion. Here, a “layer-by-layer” (LbL) approach to achieve a self-assembled monolayer (SAM) with high microbicidal effect on hydroxylated surfaces is presented, exploiting the reaction between a monolayer of thiolic functions on glass/quartz surfaces and a newly synthesized derivative of the well-known antibacterial compound silver sulfadiazine. Using several different techniques, it is demonstrated that a nano-monolayer of silver sulfadiazine is formed on the surfaces. The surface-functionalized materials showed efficient bactericidal effect against both Gram-positive and Gram-negative bacteria. Interestingly, bactericidal self-assembled nano-monolayers of silver sulfadiazine could be achieved on a large variety of materials by simply pre-depositing glass-like SiO2 films on their surfaces.

Performances of Sexithiophene Based Thin-Film Transistor Using Self-Assembled Monolayers

1997 ◽  
Vol 488 ◽  
Author(s):  
J. Collet ◽  
O. Tharaud ◽  
C. Legrand ◽  
A. Chapoton ◽  
D. Vuillaume
Keyword(s):  
Thin Film ◽  
Threshold Voltage ◽  
High Performance ◽  
Film Formation ◽  
Substrate Surface ◽  
High Surface ◽  
Thin Film Transistor ◽  
Subthreshold Slope ◽  
Self Assembled Monolayer ◽  
Self Assembled

AbstractHigh performance thin-film transistors (TFT) made of conducting oligomers are obtained when the organic films are well ordered at a molecular level. Highly ordered films are obtained provided that oligomers have a sufficient mobility on the substrate surface during film formation. One possible way to fulfill such a condition is to evaporate oligomers on heated substrates [1,2]. In this work, we suggest that a high surface mobility is obtained by a chemical functionalization of the silicon dioxide surface, and the corresponding improvements of the TFT performances are evidenced. A self-assembled monolayer of octadecyltrichlorosilane (OTS) was deposited on the SiO2 by chemisorption from solution before the evaporation of sexithiophene film. Room temperature current-voltage measurements indicate that the presence of the OTS monolayer improves TFT performances : threshold voltage is decreased, subthreshold slope is decreased, a high current ratio Ion/Ioff is obtained for a reduced gate voltage excursion, the fieldeffect mobility is slightly increased. We have also fabricated and characterized a nanometer scale organic FET (gate length = 50 nm) made of 6T films and only with a self-assembled monolayer as the insulating film between the degenerated silicon substrate (gate) and the conducting channel (no thick SiO2, we call it « oxide-free » organic FET). Performances of this nanometer size organic FETs are the following : subthreshold slope of 0.35V/dec, threshold voltage of −1.3V, effective mobility of 2×10−4 cm2/V.s.

scholarly journals High surface coverage of a self-assembled monolayer by in situ synthesis of palladium nanodeposits

Nanoscale ◽  
2017 ◽  
Vol 9 (35) ◽  
pp. 13281-13290 ◽  
Author(s):  
Lucía Herrer ◽  
Victor Sebastian ◽  
Santiago Martín ◽  
Alejandro González-Orive ◽  
Francesc Pérez-Murano ◽  
...  
Keyword(s):  
Surface Coverage ◽  
High Surface ◽  
In Situ Synthesis ◽  
Self Assembled Monolayer ◽  
Confined Growth ◽  
Growth Method ◽  
Self Assembled

Nascent metal|monolayer|metal devices have been fabricated by depositing palladium, by growing palladium nanodeposits through a CO-confined growth method.

scholarly journals Electron-Transfer Properties of Phenyleneethynylene Linkers Bound to Gold via a Self-Assembled Monolayer of Molecular Tripod

Molecules ◽  
2018 ◽  
Vol 23 (11) ◽  
pp. 2893 ◽  
Author(s):  
Toshikazu Kitagawa ◽  
Takashi Kawano ◽  
Takahiro Hase ◽  
Ikuma Hayakawa ◽  
Katsuyuki Hirai ◽  
...  
Keyword(s):  
Electron Transfer ◽  
High Surface ◽  
Gold Surface ◽  
Solid Surfaces ◽  
Self Assembled Monolayers ◽  
Self Assembled Monolayer ◽  
Assembled Monolayers ◽  
Self Assembled ◽  
Electron Transfer Properties ◽  
Transfer Properties

The three-point adsorption of tripod-shaped molecules enables the formation of robust self-assembled monolayers (SAMs) on solid surfaces, where the component molecules are fixed in a strictly upright orientation. In the present study, SAMs of a rigid molecular tripod consisting of an adamantane core and three CH2SH groups were employed to arrange ferrocene on a gold surface through oligo(p-phenyleneethynylene) linkers. Cyclic voltammetry of the monolayers demonstrated high surface coverage of ferrocene, yet the molecular interaction among adjacent ferrocene units was negligible. This was because of the extended intermolecular distance caused by the bulky tripod framework. The rates of electron transfer from the ferrocene to the gold surface through different linker lengths were determined by electrochemical measurements, from which the decay factor for oligo(p-phenyleneethynylene) wire was evaluated.

scholarly journals The Effect of Irradiation with a 405 nm Blue-Violet Laser on the Bacterial Adhesion on the Osteosynthetic Biomaterials

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Chika Terada ◽  
Takahiro Imamura ◽  
Tomoko Ohshima ◽  
Nobuko Maeda ◽  
Seiko Tatehara ◽  
...  
Keyword(s):  
Bacterial Adhesion ◽  
Postoperative Infection ◽  
Major Complication ◽  
Bactericidal Effect ◽  
Alamar Blue ◽  
Effective Prevention ◽  
Material Surfaces ◽  
Significant Difference ◽  
Redox Indicator ◽  
Colony Forming Assay

Delayed postoperative infection is known as a major complication after bone surgeries using osteosynthetic biomaterial such as titanium (Ti) and bioresorbable organic materials. However, the precise cause of this type of infection is still unclear and no effective prevention has been established. The purpose of this study is to investigate the effect of irradiation with a 405 nm blue-violet laser on the bacteria adhered on the Ti and hydroxyapatite-poly-L-lactic acid- (HA-PLLA) based material surfaces and to verify the possibility of its clinical application to prevent the delayed postoperative infection after bone surgeries using osteosynthetic biomaterial. The suspension of Staphylococcus aureus FDA 209P was delivered onto the surface of disks composed of Ti or HA-PLLA. Bacterial adhesion on each disk was observed using a scanning electron microscope (SEM). After thorough washing with distilled water, the growth of bacteria attached to the material surfaces was examined with an alamar blue-based redox indicator. Moreover, a bactericidal effect of 405 nm blue-violet laser irradiation on residual bacteria on both materials was investigated using colony-forming assay. As a result, there was no significant difference in the bacterial adhesion between Ti and HA-PLLA materials. In contrast, 45 J/cm2 of irradiation with 405 nm blue-violet laser inhibited the bacterial growth at approximately 93% on Ti disks and at approximately 99% on HA-PLLA disks. This study clearly demonstrated the possibility that the irradiation with a 405 nm blue-violet laser is useful as an alternative management strategy for the prevention of delayed postoperative infection after bone surgeries using osteosynthetic biomaterials.

An Organic Guest Molecule Induced Ultrafast Breathing of Epitaxially Grown Metal-Organic Framework on Self-Assembled Monolayer

2021 ◽  
Author(s):  
Purna Chandra Rao ◽  
Mani Prabu ◽  
Younghu Son ◽  
Jiyun Kim ◽  
Minyoung Yoon
Keyword(s):  
Thin Films ◽  
Guest Molecule ◽  
Metal Organic Framework ◽  
Layer By Layer ◽  
Epitaxial Thin Films ◽  
Two Dimensional ◽  
Self Assembled Monolayer ◽  
Metal Organic ◽  
Self Assembled ◽  
Organic Framework

We report epitaxially grown new two-dimensional metal-organic framework (MOF) thin films on self-assembled monolayer (SAM). We fabricated these epitaxial thin-films using the stepwise layer-by-layer seeding followed by solvothermal treatment. The...

scholarly journals Preparation and Antifouling Property of Polyurethane Film Modified by PHMG and HA Using Layer-by-Layer Assembly

Polymers ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 934
Author(s):  
Huihui Yuan ◽  
Chenli Xue ◽  
Jiaqian Zhu ◽  
Zhaogang Yang ◽  
Minbo Lan
Keyword(s):  
Protein Adsorption ◽  
Bacterial Adhesion ◽  
Attenuated Total Reflection ◽  
Layer By Layer ◽  
Water Contact ◽  
Antibacterial Performance ◽  
Atomic Force ◽  
Polyurethane Film ◽  
Self Assembled ◽  
Self Assembled Layer

To reduce the possibility of bacterial infection and implant-related complications, surface modification on polyurethane (PU) film is an ideal solution to endow hydrophobic PU with antibacterial and antifouling properties. In this work, a variety of polyhexamethylene guanidine/ hyaluronic acid (PHMG/HA) multilayer films were self-assembled layer-by-layer on PU films using polyanions, carboxyl-activated HA, and polycations PHMG by controlling the concentration of these polyelectrolytes as well as the number of layers self-assembled. Attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) spectra, water contact angle (WCA), and A Atomic force microscope (AFM) of PU and modified PU films were studied. Protein adsorption and bacterial adhesion as well as the cytotoxicity against L929 of the film on selected PU-(PHMG/HA)5/5-5 were estimated. The results showed that PU-(PHMG/HA)5/5-5 had the best hydrophilicity among all the prepared films, possessing the lowest level of protein adsorption. Meanwhile, this film showed efficient broad-spectrum antibacterial performance as well as significant resistance of bacterial adhesion of more than a 99.9% drop for the selected bacteria. Moreover, almost no influence on cell viability of L929 enhanced the biocompatibility of film. Therefore, the modified PU films with admirable protein absorption resistance, antimicrobial performance, and biocompatibility would have promising applications in biomedical aspect.

Self-Assembled Fluid Phase Floating Membranes with Tuneable Water Interlayers

2019 ◽  
Author(s):  
Luke Clifton ◽  
Nicoló Paracini ◽  
Arwel V. Hughes ◽  
Jeremy H. Lakey ◽  
Nina-Juliane Seinke ◽  
...  
Keyword(s):  
Fluid Phase ◽  
Interlayer Thickness ◽  
Supported Bilayers ◽  
Self Assembled Monolayer ◽  
High Coverage ◽  
Nano Technology ◽  
Surface Distance ◽  
Potential Applications ◽  
Self Assembled ◽  
Coated Surfaces

<p>We present a reliable method for the fabrication of fluid phase unsaturated bilayers which are readily self-assembled on charged self-assembled monolayer (SAM) surfaces producing high coverage floating supported bilayers where the membrane to surface distance could be controlled with nanometer precision. Vesicle fusion was used to deposit the bilayers onto anionic SAM coated surfaces. Upon assembly the bilayer to SAM solution interlayer thickness was 7-10 Å with evidence suggesting that this layer was present due to SAM hydration repulsion of the bilayer from the surface. This distance could be increased using low concentrations of salts which caused the interlayer thickness to enlarge to ~33 Å. Reducing the salt concentration resulted in a return to a shorter bilayer to surface distance. These accessible and controllable membrane models are well suited to a range of potential applications in biophysical studies, bio-sensors and Nano-technology.</p><br>

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