scholarly journals Synthesis and Characterization of Chitosan/Reduced Graphene Oxide Hybrid Composites

Materials ◽  
2019 ◽  
Vol 12 (13) ◽  
pp. 2077 ◽  
Author(s):  
Karolina Kosowska ◽  
Patrycja Domalik-Pyzik ◽  
Małgorzata Krok-Borkowicz ◽  
Jan Chłopek
Keyword(s):  
Tissue Engineering ◽  
Graphene Oxide ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Reduced Graphene Oxide ◽  
Hybrid Composites ◽  
X Ray ◽  
Reduced Graphene ◽  
Wide Range ◽  
Composite Formation

Graphene family materials (GFM) are currently considered to be one of the most interesting nanomaterials with a wide range of application. They can also be used as modifiers of polymer matrices to develop composite materials with favorable properties. In this study, hybrid nanocomposites based on chitosan (CS) and reduced graphene oxide (rGO) were fabricated for potential use in bone tissue engineering. CS/rGO hydrogels were prepared by simultaneous reduction and composite formation in acetic acid or lactic acid and crosslinked with a natural agent—tannic acid (TAc). A broad spectrum of research methods was applied in order to thoroughly characterize both the components and the composite systems, i.e., X-ray Photoelectron Spectroscopy, X-ray Diffractometry, Attenuated Total Reflection Fourier-Transform Infrared Spectroscopy, Scanning Electron Microscopy, ninhydrin assay, mechanical testing, in vitro degradation and bioactivity study, wettability, and, finally, cytocompatibility. The composites formed through the self-assembly of CS chains and exfoliated rGO sheets. Obtained results allowed also to conclude that the type of solvent used impacts the polymer structure and its ability to interact with rGO sheets and the mechanical properties of the composites. Both rGO and TAc acted as crosslinkers of the polymer chains. This study shows that the developed materials demonstrate the potential for use in bone tissue engineering. The next step should be their detailed biological examinations.

scholarly journals Reduced graphene oxide: osteogenic potential for bone tissue engineering

2019 ◽  
Vol 13 (7) ◽  
pp. 720-725 ◽  
Author(s):  
Mohammad Hadi Norahan ◽  
Masoud Amroon ◽  
Ramin Ghahremanzadeh ◽  
Navid Rabiee ◽  
Nafiseh Baheiraei
Keyword(s):  
Tissue Engineering ◽  
Graphene Oxide ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Reduced Graphene Oxide ◽  
Osteogenic Potential ◽  
Reduced Graphene

scholarly journals Facile Fabrication of CeO2/Electrochemically Reduced Graphene Oxide Nanocomposites for Vanillin Detection in Commercial Food Products

Nanomaterials ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 1356 ◽  
Author(s):  
Xue Nie ◽  
Rui Zhang ◽  
Zheng Tang ◽  
Haiyan Wang ◽  
Peihong Deng ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Linear Sweep Voltammetry ◽  
X Ray ◽  
Transmission Electron ◽  
Reduced Graphene ◽  
Electrochemically Reduced Graphene Oxide ◽  
Wide Range ◽  
Facile Fabrication

In this paper, CeO2 nanoparticles were synthesized by the solvothermal method and dispersed uniformly in graphene oxide (GO) aqueous solution by ultrasonication. The homogeneous CeO2-GO dispersion was coated on the surface of a glassy carbon electrode (GCE), and the CeO2/electrochemically reduced graphene oxide modified electrode (CeO2/ERGO/GCE) was obtained by potentiostatic reduction. The results of X-ray diffraction (XRD), energy dispersive X-ray spectroscopy (EDS), scanning electron microscopy (SEM), and transmission electron microscopy (TEM) showed that CeO2 nanocrystals were uniformly coated by gossamer like ERGO nanosheets. The electrochemical behavior of vanillin on the CeO2/ERGO/GCE was studied by cyclic voltammetry (CV). It was found that the CeO2/ERGO/GCE has high electrocatalytic activity and good electrochemical performance for vanillin oxidation. Using the second derivative linear sweep voltammetry (SDLSV), the CeO2/ERGO/GCE provides a wide range of 0.04–20 µM and 20 µM–100 µM for vanillin detection, and the detection limit is estimated to be 0.01 µM after 120 s accumulation. This method has been successfully applied to the vanillin detection in some commercial foods.

scholarly journals Antibacterial Performance of a Mussel-Inspired Polydopamine-Treated Ag/Graphene Nanocomposite Material

Materials ◽  
2019 ◽  
Vol 12 (20) ◽  
pp. 3360
Author(s):  
Jianming Liao ◽  
Shuaiming He ◽  
Shasha Guo ◽  
Pengcheng Luan ◽  
Lihuan Mo ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Antibacterial Properties ◽  
Great Promise ◽  
X Ray ◽  
Antibacterial Performance ◽  
Reduced Graphene ◽  
Wide Range ◽  
Graphene Nanocomposite

Graphene-based nanocomposites have attracted tremendous attention in recent years. In this study, a facile yet effective approach was developed to synthesize reduced graphene oxide and an Ag–graphene nanocomposite. The basic strategy involved in the preparation of reduced graphene oxide includes reducing graphene oxide with dopamine, followed by in situ syntheses of the Ag-PDA-reducing graphene oxide (RGO) nanocomposite through adding AgNO3 solution and a small amount of dopamine. The nanocomposite was characterized by transmission electron microscopy (TEM), atomic force microscopy (AFM), X-ray diffraction (XRD), FTIR spectra, Raman spectra, ultraviolet-visible (UV-vis), and X-ray photoelectron spectroscopy (XPS), results indicated that a uniform PDA film is formed on the surface of the GO and GO is successfully reduced. Besides, the in situ synthesized Ag nanoparticles (AgNPs) were evenly distributed on the RGO surface. To investigate antibacterial properties Ag-PDA-RGO, different dosages were selected for evaluating the antibacterial activity against Gram-positive bacteria Staphylococcus aureus and Gram-negative bacteria Escherichia coli. The Ag-PDA-RGO nanocomposites displayed excellent antibacterial property. The antibacterial ratio reached 99.9% against S. aureus and 90.9% against E. coli when the dosage of 100 mg/L Ag-PDA-RGO nanocomposites was 100 μL. The novel Ag-PDA-RGO nanocomposite prepared by a facile yet effective, environmentally friendly, and low-cost method holds great promise in a wide range of modern biomedical applications.

scholarly journals Oxygen Plasma Technology-Assisted Preparation of Three-Dimensional Reduced Graphene Oxide/Polypyrrole/Strontium Composite Scaffold for Repair of Bone Defects Caused by Osteoporosis

Molecules ◽  
2021 ◽  
Vol 26 (15) ◽  
pp. 4451
Author(s):  
Xiaoxue Mai ◽  
Zebiao Kang ◽  
Na Wang ◽  
Xiaoli Qin ◽  
Weibo Xie ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Graphene Oxide ◽  
Bone Tissue Engineering ◽  
Reduced Graphene Oxide ◽  
Oxygen Plasma ◽  
Composite Scaffold ◽  
Three Dimensional ◽  
Bone Defects ◽  
Plasma Technology ◽  
Reduced Graphene

Repairs of bone defects caused by osteoporosis have always relied on bone tissue engineering. However, the preparation of composite tissue engineering scaffolds with a three-dimensional (3D) macroporous structure poses huge challenges in achieving osteoconduction and osteoinduction for repairing bone defects caused by osteoporosis. In the current study, a three-dimensional macroporous (150–300 μm) reduced graphene oxide/polypyrrole composite scaffold modified by strontium (Sr) (3D rGO/PPY/Sr) was successfully prepared using the oxygen plasma technology-assisted method, which is simple, safe, and inexpensive. The findings of the MTT assay and AO/EB fluorescence double staining showed that 3D rGO/PPY/Sr has a good biocompatibility and effectively promoted MC3T3-E1 cell proliferation. Furthermore, the ALP assay and alizarin red staining showed that 3D rGO/PPY/Sr increased the expression levels of ALP activity and the formation of calcified nodules. The desirable biocompatibility, osteoconduction, and osteoinduction abilities, assure that the 3D macroporous rGO/PPY/Sr composite scaffold offers promising potential for use in the repair of bone defects caused by osteoporosis in bone tissue engineering.

Facile one pot microbe-mediated in situ synthesis and antibacterial activity of reduced graphene oxide-silver nanocomposite

2021 ◽  
Author(s):  
Ashwini Patil
Keyword(s):  
Antibacterial Activity ◽  
Graphene Oxide ◽  
Zeta Potential ◽  
Reduced Graphene Oxide ◽  
In Vitro Dissolution ◽  
Size Analysis ◽  
X Ray ◽  
Reduced Graphene

Abstract The present research deals with the development of a novel bioinspired in situ fabrication of reduced graphene oxide (rGO)-silver nanoparticle (AgNPs) nanocomposite (rGO@AgNCs) using microbes namely Pseudomonas aeruginosa (PA) and Staphylococcus aureus (SA). The fabricated rGO@AgNCs were characterized using Ultraviolet-visible (UV) spectroscopy, Fourier-transform infrared spectroscopy (FTIR), particle size analysis, polydispersity index (PDI), zeta potential analysis, energy dispersive X-ray analysis (EDAX), Raman spectroscopy, powder X-ray diffraction (PXRD), high-resolution transmission electron microscopy (HR-TEM) analysis, etc. Furthermore, the rGO@AgNCs-PA and rGO@AgNCs-SA interaction with serum protein, pH stability study, and in vitro dissolution of AgNPs were also performed. The research findings of the proposed study demonstrated the simultaneous reduction of graphene oxide (GO) and AgNPs and the formation of rGO@AgNCs in the presence of microbes. The in vitro dissolution studies of rGO@AgNCs composites showed better AgNPs dissolution with controlled release and offered remarkable matrix integrity throughout the dissolution period. The size and stability of rGO@AgNCs-PA and rGO@AgNCs-SA had no significant changes at physiological pH 7.4. A minimal decrease in the zeta potential of rGO@AgNCs was observed, which may be due to the weak interaction of nanocomposites and albumin. The antibacterial application of the synthesized nanocomposite was evaluated against a pathogenic mastitis-forming bacterium. The obtained results suggested an admirable antibacterial activity of synthesized nanocomposites against the tested microbes. This knowledge will assist the scientific fraternity in designing novel antibacterial agents with enhanced antibacterial activity against various veterinary pathogens in near future.

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