scholarly journals Freeform Perfusable Microfluidics Embedded in Hydrogel Matrices

Materials ◽  
2018 ◽  
Vol 11 (12) ◽  
pp. 2529 ◽  
Author(s):  
Gabriela Štumberger ◽  
Boštjan Vihar
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Rapid Prototyping ◽  
Xanthan Gum ◽  
Vascular Grafts ◽  
Microfluidic Devices ◽  
Simple Method ◽  
New Approach ◽  
Hydrogel Matrix ◽  
Printing Method

We report a modification of the freeform reversible embedding of suspended hydrogels (FRESH) 3D printing method for the fabrication of freeform perfusable microfluidics inside a hydrogel matrix. Xanthan gum is deposited into a CaCl2 infused gelatine slurry to form filaments, which are consequently rinsed to produce hollow channels. This provides a simple method for rapid prototyping of microfluidic devices based on biopolymers and potentially a new approach to the construction of vascular grafts for tissue engineering.

scholarly journals Freeform Perfusable Microfluidics Embedded in Hydrogel Matrices

2018 ◽  
Author(s):  
Gabriela Štumberger ◽  
Boštjan Vihar
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Rapid Prototyping ◽  
Xanthan Gum ◽  
Vascular Grafts ◽  
Microfluidic Devices ◽  
Simple Method ◽  
New Approach ◽  
Hydrogel Matrix ◽  
Printing Method

We report a modification of the freeform reversible embedding of suspended hydrogels (FRESH) 3D printing method for the fabrication of freeform perfusable microfluidics inside a hydrogel matrix. Xanthan gum is deposited into a CaCl2 infused gelatin slurry to form filaments, which are consequently rinsed to produce hollow channels. This provides a simple method for rapid prototyping of microfluidic devices based on biopolymers and potentially a new approach to the construction of vascular grafts for tissue engineering.

scholarly journals Fabrication of unconventional inertial microfluidic channels using wax 3D printing

Soft Matter ◽  
2020 ◽  
Vol 16 (10) ◽  
pp. 2448-2459 ◽  
Author(s):  
Mohammad Amin Raoufi ◽  
Sajad Razavi Bazaz ◽  
Hamid Niazmand ◽  
Omid Rouhi ◽  
Mohsen Asadnia ◽  
...  
Keyword(s):  
3D Printing ◽  
Microfluidic Devices ◽  
Microfluidic Channels ◽  
Printing Method

A novel workflow for the fabrication of inertial microfluidic devices based on the wax 3D printing method.

Empowering microfluidics by micro-3D printing and solution-based mineral coating

Soft Matter ◽  
2020 ◽  
Vol 16 (29) ◽  
pp. 6841-6849
Author(s):  
Hongxia Li ◽  
Aikifa Raza ◽  
Qiaoyu Ge ◽  
Jin-You Lu ◽  
TieJun Zhang
Keyword(s):  
3D Printing ◽  
Microfluidic Devices ◽  
Environmental Applications ◽  
New Approach

This work presents a new approach to additively fabricate functional porous microfluidic devices, by micro-3D printing and solution-based mineral coating, for energy and environmental applications.

Characterization and preparation of bio-tubular scaffolds for fabricating artificial vascular grafts by combining electrospinning and a 3D printing system

2015 ◽  
Vol 17 (5) ◽  
pp. 2996-2999 ◽  
Author(s):  
Sang Jin Lee ◽  
Dong Nyoung Heo ◽  
Ji Sun Park ◽  
Seong Keun Kwon ◽  
Jin Ho Lee ◽  
...  
Keyword(s):  
3D Printing ◽  
Rapid Prototyping ◽  
Blood Vessels ◽  
Vascular Grafts ◽  
Artificial Blood ◽  
System P ◽  
Artificial Blood Vessels ◽  
Printing System

This study describes the design and fabrication of artificial blood vessels composed of a blend of CTS and PCL ENs and coated with PCL strands using rapid prototyping technology.

The Use of Rapid Prototyping to Fabricate Liver Tissue Engineering Scaffold

2011 ◽  
Vol 328-330 ◽  
pp. 658-661
Author(s):  
Singare Sekou ◽  
Shou Yan Zhong ◽  
Zhen Zhong Sun
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Rapid Prototyping ◽  
Glycolic Acid ◽  
Tissue Engineering Scaffold ◽  
Liver Tissue Engineering ◽  
Biodegradable Poly ◽  
Future Direction ◽  
Silicone Mould ◽  
Printing Machine

In this papers, the authors described a rapid prototyping method to produce vascularized tissue such liver scaffold for tissue engineering applications. A scaffold with interconnected channel was designed using CAD environment. The data were transferred to a Polyjet 3D Printing machine (Eden 250, Object, Israel) to generate the models. Based on the 3D Printing model, a PDMS (polydimethyl-silicone) mould was created which can be used to cast the biodegradable poly (L-lactic-co-glycolic acid) (PLGA )material. The advantages and limitations of Rapid Prototyping (RP) techniques as well as the future direction of RP development in tissue engineering scaffold fabrication were reviewed.

Desarrollo de un Sistema de Cultivo Tisular Híbrido y Multicomponente Usando Polímeros de Soporte Impresos 3D

2021 ◽  
Author(s):  
◽  
C. A. Romero Zepeda
Keyword(s):  
Tissue Engineering ◽  
Pharmaceutical Industry ◽  
3D Printing ◽  
Low Cost ◽  
Three Dimensional ◽  
Alternative Methods ◽  
Structural Elements ◽  
Different Types ◽  
Organ On A Chip ◽  
Printing Method

The development of different types of Organ on a Chip has attract the attention of pharmaceutical industry to develop alternative methods for ensuring the efficiency of drugs before approval. A dual bioprinting-culturing system was developed to construct the needed elements needed for creating three dimensional tissues including the corresponding instrumented device that may keep the environment conditions that may reinforce the cells´ growth. The proposed 3D printing platform considering the principles of an Organ on a Chip for the creation of a hybrid system of scaffolds for tissue engineering using polylactic acid. The usage of the 3D printing method allows the modification and creation of a flexible platform with different structures to a low cost, including the possibility of introducing the structural elements to create multi component tissues. The developed system was tested using a traditional fibroblasts culture.

Microfluidic Devices and 3D Printing for Synthesis and Screening of Drugs and Tissue Engineering

2019 ◽  
Vol 59 (9) ◽  
pp. 3794-3810 ◽  
Author(s):  
Harrson S. Santana ◽  
Mauri S. A. Palma ◽  
Mariana G. M. Lopes ◽  
Johmar Souza ◽  
Giovanni A. S. Lima ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Microfluidic Devices

3D printing enables the rapid prototyping of modular microfluidic devices for particle conjugation

2020 ◽  
Vol 20 ◽  
pp. 100726 ◽  
Author(s):  
Steven A. Vasilescu ◽  
Sajad Razavi Bazaz ◽  
Dayong Jin ◽  
Olga Shimoni ◽  
Majid Ebrahimi Warkiani
Keyword(s):  
3D Printing ◽  
Rapid Prototyping ◽  
Microfluidic Devices

scholarly journals Rapid Prototyping of Cell Culture Microdevices Using Parylene-Coated 3D Prints

Lab on a Chip ◽  
2021 ◽  
Author(s):  
Brian O'Grady ◽  
Michael Geuy ◽  
Hyosung Kim ◽  
Kylie Balotin ◽  
Everett Allchin ◽  
...  
Keyword(s):  
Cell Culture ◽  
3D Printing ◽  
Rapid Prototyping ◽  
Microfluidic Devices ◽  
Cost Effective ◽  
Specialized Training ◽  
Complex Features

Fabrication of microfluidic devices by photolithography generally requires specialized training and access to a cleanroom. As an alternative, 3D printing enables cost-effective fabrication of microdevices with complex features that would...

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