Empowering microfluidics by micro-3D printing and solution-based mineral coating

Soft Matter ◽  
2020 ◽  
Vol 16 (29) ◽  
pp. 6841-6849
Author(s):  
Hongxia Li ◽  
Aikifa Raza ◽  
Qiaoyu Ge ◽  
Jin-You Lu ◽  
TieJun Zhang
Keyword(s):  
3D Printing ◽  
Microfluidic Devices ◽  
Environmental Applications ◽  
New Approach

This work presents a new approach to additively fabricate functional porous microfluidic devices, by micro-3D printing and solution-based mineral coating, for energy and environmental applications.

scholarly journals Freeform Perfusable Microfluidics Embedded in Hydrogel Matrices

Materials ◽  
2018 ◽  
Vol 11 (12) ◽  
pp. 2529 ◽  
Author(s):  
Gabriela Štumberger ◽  
Boštjan Vihar
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Rapid Prototyping ◽  
Xanthan Gum ◽  
Vascular Grafts ◽  
Microfluidic Devices ◽  
Simple Method ◽  
New Approach ◽  
Hydrogel Matrix ◽  
Printing Method

We report a modification of the freeform reversible embedding of suspended hydrogels (FRESH) 3D printing method for the fabrication of freeform perfusable microfluidics inside a hydrogel matrix. Xanthan gum is deposited into a CaCl2 infused gelatine slurry to form filaments, which are consequently rinsed to produce hollow channels. This provides a simple method for rapid prototyping of microfluidic devices based on biopolymers and potentially a new approach to the construction of vascular grafts for tissue engineering.

scholarly journals Freeform Perfusable Microfluidics Embedded in Hydrogel Matrices

2018 ◽  
Author(s):  
Gabriela Štumberger ◽  
Boštjan Vihar
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Rapid Prototyping ◽  
Xanthan Gum ◽  
Vascular Grafts ◽  
Microfluidic Devices ◽  
Simple Method ◽  
New Approach ◽  
Hydrogel Matrix ◽  
Printing Method

We report a modification of the freeform reversible embedding of suspended hydrogels (FRESH) 3D printing method for the fabrication of freeform perfusable microfluidics inside a hydrogel matrix. Xanthan gum is deposited into a CaCl2 infused gelatin slurry to form filaments, which are consequently rinsed to produce hollow channels. This provides a simple method for rapid prototyping of microfluidic devices based on biopolymers and potentially a new approach to the construction of vascular grafts for tissue engineering.

Understanding and improving FDM 3D printing to fabricate high-resolution and optically transparent microfluidic devices

Lab on a Chip ◽  
2021 ◽  
Author(s):  
Reverson Fernandes Quero ◽  
Gessica Domingos Silveira ◽  
Jose Alberto Fracassi da Silva ◽  
Dosil Pereira de Jesus
Keyword(s):  
High Resolution ◽  
3D Printing ◽  
Fused Deposition Modeling ◽  
Microfluidic Devices ◽  
Fused Deposition ◽  
Optically Transparent ◽  
Deposition Modeling

The fabrication of microfluidic devices through Fused Deposition Modeling (FDM) 3D printing has faced several challenges, mainly regarding obtaining microchannels with suitable transparency and sizes. Thus, the use of this...

Simplified fabrication of integrated microfluidic devices using fused deposition modeling 3D printing

2017 ◽  
Vol 242 ◽  
pp. 35-40 ◽  
Author(s):  
Gabriel Gaal ◽  
Melissa Mendes ◽  
Tiago P. de Almeida ◽  
Maria H.O. Piazzetta ◽  
Ângelo L. Gobbi ◽  
...  
Keyword(s):  
3D Printing ◽  
Fused Deposition Modeling ◽  
Microfluidic Devices ◽  
Fused Deposition ◽  
Deposition Modeling

scholarly journals Dual Sacrificial Molding: Fabricating 3D Microchannels with Overhang and Helical Features

Micromachines ◽  
2018 ◽  
Vol 9 (10) ◽  
pp. 523 ◽  
Author(s):  
Wei Goh ◽  
Michinao Hashimoto
Keyword(s):  
3D Printing ◽  
Fused Deposition Modeling ◽  
Microfluidic Devices ◽  
High Impact ◽  
3D Printer ◽  
Original Design ◽  
Fused Deposition ◽  
Deposition Modeling ◽  
Indispensable Tool ◽  
Single Material

Fused deposition modeling (FDM) has become an indispensable tool for 3D printing of molds used for sacrificial molding to fabricate microfluidic devices. The freedom of design of a mold is, however, restricted to the capabilities of the 3D printer and associated materials. Although FDM has been used to create a sacrificial mold made with polyvinyl alcohol (PVA) to produce 3D microchannels, microchannels with free-hanging geometries are still difficult to achieve. Herein, dual sacrificial molding was devised to fabricate microchannels with overhang or helical features in PDMS using two complementary materials. The method uses an FDM 3D printer equipped with two extruders and filaments made of high- impact polystyrene (HIPS) and PVA. HIPS was initially removed in limonene to reveal the PVA mold harboring the design of microchannels. The PVA mold was embedded in PDMS and subsequently removed in water to create microchannels with 3D geometries such as dual helices and multilayer pyramidal networks. The complementary pairing of the HIPS and PVA filaments during printing facilitated the support of suspended features of the PVA mold. The PVA mold was robust and retained the original design after the exposure to limonene. The resilience of the technique demonstrated here allows us to create microchannels with geometries not attainable with sacrificial molding with a mold printed with a single material.

scholarly journals Fabrication of unconventional inertial microfluidic channels using wax 3D printing

Soft Matter ◽  
2020 ◽  
Vol 16 (10) ◽  
pp. 2448-2459 ◽  
Author(s):  
Mohammad Amin Raoufi ◽  
Sajad Razavi Bazaz ◽  
Hamid Niazmand ◽  
Omid Rouhi ◽  
Mohsen Asadnia ◽  
...  
Keyword(s):  
3D Printing ◽  
Microfluidic Devices ◽  
Microfluidic Channels ◽  
Printing Method

A novel workflow for the fabrication of inertial microfluidic devices based on the wax 3D printing method.

Fabrication of integrated microfluidic devices by direct ink writing (DIW) 3D printing

2019 ◽  
Vol 297 ◽  
pp. 126609 ◽  
Author(s):  
Terry Ching ◽  
Yingying Li ◽  
Rahul Karyappa ◽  
Akihiro Ohno ◽  
Yi-Chin Toh ◽  
...  
Keyword(s):  
3D Printing ◽  
Microfluidic Devices ◽  
Direct Ink Writing

scholarly journals Rapid and Inexpensive Fabrication of Multi-Depth Microfluidic Device using High-Resolution LCD Stereolithographic 3D Printing

2019 ◽  
Vol 3 (1) ◽  
pp. 26 ◽  
Author(s):  
Mohamed Mohamed ◽  
Hitendra Kumar ◽  
Zongjie Wang ◽  
Nicholas Martin ◽  
Barry Mills ◽  
...  
Keyword(s):  
High Resolution ◽  
3D Printing ◽  
Soft Lithography ◽  
Liquid Crystal Display ◽  
Three Dimensional ◽  
Microfluidic Devices ◽  
Single Step ◽  
Droplet Generator ◽  
Rapid Fabrication ◽  
Printing System

With the dramatic increment of complexity, more microfluidic devices require 3D structures, such as multi-depth and -layer channels. The traditional multi-step photolithography is time-consuming and labor-intensive and also requires precise alignment during the fabrication of microfluidic devices. Here, we present an inexpensive, single-step, and rapid fabrication method for multi-depth microfluidic devices using a high-resolution liquid crystal display (LCD) stereolithographic (SLA) three-dimensional (3D) printing system. With the pixel size down to 47.25 μm, the feature resolutions in the horizontal and vertical directions are 150 μm and 50 μm, respectively. The multi-depth molds were successfully printed at the same time and the multi-depth features were transferred properly to the polydimethylsiloxane (PDMS) having multi-depth channels via soft lithography. A flow-focusing droplet generator with a multi-depth channel was fabricated using the presented 3D printing method. Experimental results show that the multi-depth channel could manipulate the morphology and size of droplets, which is desired for many engineering applications. Taken together, LCD SLA 3D printing is an excellent alternative method to the multi-step photolithography for the fabrication of multi-depth microfluidic devices. Taking the advantages of its controllability, cost-effectiveness, and acceptable resolution, LCD SLA 3D printing can have a great potential to fabricate 3D microfluidic devices.

scholarly journals Highly Fluorinated Methacrylates for Optical 3D Printing of Microfluidic Devices

Micromachines ◽  
2018 ◽  
Vol 9 (3) ◽  
pp. 115 ◽  
Author(s):  
Frederik Kotz ◽  
Patrick Risch ◽  
Dorothea Helmer ◽  
Bastian Rapp
Keyword(s):  
3D Printing ◽  
Microfluidic Devices
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