scholarly journals Biocompatible and Implantable Optical Fibers and Waveguides for Biomedicine

Materials ◽  
2018 ◽  
Vol 11 (8) ◽  
pp. 1283 ◽  
Author(s):  
Roya Nazempour ◽  
Qianyi Zhang ◽  
Ruxing Fu ◽  
Xing Sheng

Optical fibers and waveguides in general effectively control and modulate light propagation, and these tools have been extensively used in communication, lighting and sensing. Recently, they have received increasing attention in biomedical applications. By delivering light into deep tissue via these devices, novel applications including biological sensing, stimulation and therapy can be realized. Therefore, implantable fibers and waveguides in biocompatible formats with versatile functionalities are highly desirable. In this review, we provide an overview of recent progress in the exploration of advanced optical fibers and waveguides for biomedical applications. Specifically, we highlight novel materials design and fabrication strategies to form implantable fibers and waveguides. Furthermore, their applications in various biomedical fields such as light therapy, optogenetics, fluorescence sensing and imaging are discussed. We believe that these newly developed fiber and waveguide based devices play a crucial role in advanced optical biointerfaces.

2017 ◽  
Vol 5 (7) ◽  
pp. 1204-1229 ◽  
Author(s):  
Rahila Batul ◽  
Tasnuva Tamanna ◽  
Abdul Khaliq ◽  
Aimin Yu

An overview of polydopamine derived nanostructures; PDA NPs, capsules, core-shell nanostructures and PDA coatings as well as their application in various biomedical fields.


2014 ◽  
Vol 2 (22) ◽  
pp. 3413-3426 ◽  
Author(s):  
Cheng-Cheng Song ◽  
Fu-Sheng Du ◽  
Zi-Chen Li

This article summarizes recent progress in the design and synthesis of various oxidation-responsive polymers and their application in biomedical fields.


2019 ◽  
Vol 26 (38) ◽  
pp. 6834-6850 ◽  
Author(s):  
Mohammad Omaish Ansari ◽  
Kalamegam Gauthaman ◽  
Abdurahman Essa ◽  
Sidi A. Bencherif ◽  
Adnan Memic

: Nanobiotechnology has huge potential in the field of regenerative medicine. One of the main drivers has been the development of novel nanomaterials. One developing class of materials is graphene and its derivatives recognized for their novel properties present on the nanoscale. In particular, graphene and graphene-based nanomaterials have been shown to have excellent electrical, mechanical, optical and thermal properties. Due to these unique properties coupled with the ability to tune their biocompatibility, these nanomaterials have been propelled for various applications. Most recently, these two-dimensional nanomaterials have been widely recognized for their utility in biomedical research. In this review, a brief overview of the strategies to synthesize graphene and its derivatives are discussed. Next, the biocompatibility profile of these nanomaterials as a precursor to their biomedical application is reviewed. Finally, recent applications of graphene-based nanomaterials in various biomedical fields including tissue engineering, drug and gene delivery, biosensing and bioimaging as well as other biorelated studies are highlighted.


Nanomaterials ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 906
Author(s):  
Le Minh Tu Phan ◽  
Thuy Anh Thu Vo ◽  
Thi Xoan Hoang ◽  
Sungbo Cho

Recently, photothermal therapy (PTT) has emerged as one of the most promising biomedical strategies for different areas in the biomedical field owing to its superior advantages, such as being noninvasive, target-specific and having fewer side effects. Graphene-based hydrogels (GGels), which have excellent mechanical and optical properties, high light-to-heat conversion efficiency and good biocompatibility, have been intensively exploited as potential photothermal conversion materials. This comprehensive review summarizes the current development of graphene-integrated hydrogel composites and their application in photothermal biomedicine. The latest advances in the synthesis strategies, unique properties and potential applications of photothermal-responsive GGel nanocomposites in biomedical fields are introduced in detail. This review aims to provide a better understanding of the current progress in GGel material fabrication, photothermal properties and potential PTT-based biomedical applications, thereby aiding in more research efforts to facilitate the further advancement of photothermal biomedicine.


Author(s):  
Deming He ◽  
Minmin Yan ◽  
Pengjuan Sun ◽  
Yuanqiang Sun ◽  
Lingbo Qu ◽  
...  

2021 ◽  
Author(s):  
Yu Fu ◽  
Lei Yang ◽  
Jianhua Zhang ◽  
Junfei Hu ◽  
Gaigai Duan ◽  
...  

This review focuses on the recent progress in polydopamine antibacterial materials, including their structural and functional features, preparation strategies, antibacterial mechanisms, and their biomedical applications.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Esteban Gonzalez-Valencia ◽  
Ignacio Del Villar ◽  
Pedro Torres

AbstractWith the goal of ultimate control over the light propagation, photonic crystals currently represent the primary building blocks for novel nanophotonic devices. Bloch surface waves (BSWs) in periodic dielectric multilayer structures with a surface defect is a well-known phenomenon, which implies new opportunities for controlling the light propagation and has many applications in the physical and biological science. However, most of the reported structures based on BSWs require depositing a large number of alternating layers or exploiting a large refractive index (RI) contrast between the materials constituting the multilayer structure, thereby increasing the complexity and costs of manufacturing. The combination of fiber–optic-based platforms with nanotechnology is opening the opportunity for the development of high-performance photonic devices that enhance the light-matter interaction in a strong way compared to other optical platforms. Here, we report a BSW-supporting platform that uses geometrically modified commercial optical fibers such as D-shaped optical fibers, where a few-layer structure is deposited on its flat surface using metal oxides with a moderate difference in RI. In this novel fiber optic platform, BSWs are excited through the evanescent field of the core-guided fundamental mode, which indicates that the structure proposed here can be used as a sensing probe, along with other intrinsic properties of fiber optic sensors, as lightness, multiplexing capacity and easiness of integration in an optical network. As a demonstration, fiber optic BSW excitation is shown to be suitable for measuring RI variations. The designed structure is easy to manufacture and could be adapted to a wide range of applications in the fields of telecommunications, environment, health, and material characterization.


Sensors ◽  
2021 ◽  
Vol 21 (3) ◽  
pp. 703
Author(s):  
Sung-Gu Kang ◽  
Min-Su Song ◽  
Joon-Woo Kim ◽  
Jung Woo Lee ◽  
Jeonghyun Kim

Near-field communication (NFC) is a low-power wireless communication technology used in contemporary daily life. This technology contributes not only to user identification and payment methods, but also to various biomedical fields such as healthcare and disease monitoring. This paper focuses on biomedical applications among the diverse applications of NFC. It addresses the benefits of combining traditional and new sensors (temperature, pressure, electrophysiology, blood flow, sweat, etc.) with NFC technology. Specifically, this report describes how NFC technology, which is simply applied in everyday life, can be combined with sensors to present vision and opportunities to modern people.


2021 ◽  
Author(s):  
Jie Liu ◽  
Jun Huang ◽  
Peikun Xin ◽  
Guiting Liu ◽  
Jun Wu

Spurred by the structure, metabolism, and derivatives of methionine, this review systematically summarizes its recent progress in functional modification, cancer treatment, liver disease therapy.


Materials ◽  
2021 ◽  
Vol 14 (8) ◽  
pp. 1972
Author(s):  
Agnieszka Gierej ◽  
Thomas Geernaert ◽  
Sandra Van Vlierberghe ◽  
Peter Dubruel ◽  
Hugo Thienpont ◽  
...  

The limited penetration depth of visible light in biological tissues has encouraged researchers to develop novel implantable light-guiding devices. Optical fibers and waveguides that are made from biocompatible and biodegradable materials offer a straightforward but effective approach to overcome this issue. In the last decade, various optically transparent biomaterials, as well as different fabrication techniques, have been investigated for this purpose, and in view of obtaining fully fledged optical fibers. This article reviews the state-of-the-art in the development of biocompatible and biodegradable optical fibers. Whilst several reviews that focus on the chemical properties of the biomaterials from which these optical waveguides can be made have been published, a systematic review about the actual optical fibers made from these materials and the different fabrication processes is not available yet. This prompted us to investigate the essential properties of these biomaterials, in view of fabricating optical fibers, and in particular to look into the issues related to fabrication techniques, and also to discuss the challenges in the use and operation of these optical fibers. We close our review with a summary and an outline of the applications that may benefit from these novel optical waveguides.


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