scholarly journals Ethyl 1-butyl-2-(2-hydroxy-4-methoxyphenyl)-1H-benzo[d]imidazole-5-carboxylate

Molbank ◽  
10.3390/m1192 ◽  
2021 ◽  
Vol 2021 (1) ◽  
pp. M1192
Author(s):  
Reshma Sathyanarayana ◽  
Boja Poojary
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Molecular Electrostatic Potential ◽  
Emission Spectra ◽  
Sodium Dithionite ◽  
Proton Nuclear Magnetic Resonance ◽  
One Pot ◽  
Ft Ir ◽  
Fourier Transfer Infrared Spectroscopy ◽  
Nuclear Magnetic

Ethyl 4-(butylamino)-3-nitrobenzoate upon “one-pot” nitro-reductive cyclization using sodium dithionite and substituted aldehyde in dimethyl sulphoxide affords ethyl 1-butyl-2-(2-hydroxy-4-methoxyphenyl)-1H-benzo[d]imidazole-5-carboxylate in an 87% yield. The structural characterization was determined by Fourier-transfer infrared spectroscopy (FT-IR), Proton nuclear magnetic resonance (1H-NMR) , Carbon-13 nuclear magnetic resonance (13C-NMR), mass spectrometry, Ultraviolet-visible(UV-Vis), photoluminescence (PL), thin-film solid emission spectra, cyclic voltammetry (CV) and thermogravimetric (TGA) analysis. Molecular electrostatic potential (MEP) was studied to determine the reactive sites of the molecule.

scholarly journals One-Pot Synthesis of 7, 7-Dimethyl-4-Phenyl-2-Thioxo-2,3,4,6,7, 8-Hexahydro-1H-Quinazoline-5-OnesUsing Zinc Ferrite Nanocatalyst and Its Bio Evaluation

Catalysts ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 431
Author(s):  
Tentu Nageswara Rao ◽  
Nalla Krishnarao ◽  
Faheem Ahmed ◽  
Suliman Yousef Alomar ◽  
Fadwa Albalawi ◽  
...  
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Zinc Ferrite ◽  
Large Scale ◽  
Cyano Group ◽  
Proton Nuclear Magnetic Resonance ◽  
Scale Production ◽  
One Pot ◽  
Antibacterial And Antifungal ◽  
Nuclear Magnetic

A simple and highly efficient protocol for the synthesis of derivatives 7, 7-dimethyl-4-phenyl-2-thioxo-2, 3, 4, 6, 7, 8-hexahydro-1H-quinazoline-5-one from 5, 5-dimethyl cyclohexane-1, 3-dione (4a–4h) (dimedone) has been described. The aryl aldehydes were substituted with thiourea in the presence of synthesized zinc ferrite nanocatalyst, which increased the yield under reflux through condensation, followed by cyclization to give desired products. The other advantages are that it is eco-friendly and economically affordable for large-scale production. Structural validation and characterization of all the newly synthesized compounds were evaluated by spectral analysis (mass spectrometry, proton nuclear magnetic resonance (1HNMR), and Carbon-13 nuclear magnetic resonance(13CNMR)spectroscopies. The structure of antibacterial and antifungal assays was performed with the newly synthesized compounds. The antimicrobial activity of title compounds possessing electron-withdrawing groups such as (4e–4h) (Cl, Br, and cyano group) exhibited more active potential than the electron-donating groups, C6H5,4-C6H4, 3-OC2H5-4OH-C6H3, etc., (4a–4d) containing moiety.

scholarly journals Synthesis, Characterization, and Crystal Structures of Imides Condensed with p-Phenylamino(Phenyl) Amine and Fluorescence Property

Materials ◽  
2019 ◽  
Vol 12 (11) ◽  
pp. 1873
Author(s):  
Jing Zhang ◽  
Huaibo Ma
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Fluorescence Emission ◽  
Emission Spectra ◽  
Differential Pulse ◽  
Proton Nuclear Magnetic Resonance ◽  
Cyclic Voltammogram ◽  
Fluorescence Emission Spectra ◽  
Thermal Stabilities ◽  
Nuclear Magnetic

A series of aromatic diimide and monoimide compounds condensed with p-phenylamino(phenyl)amine were synthesized and confirmed by Proton Nuclear Magnetic Resonance (1H NMR), Carbon-13 Nuclear Magnetic Resonance (13C NMR), Fourier Transform Infrared Spectroscopy (FT-IR), Elemental Analysis (EA), and High Resolution Mass Spectroscopy (HRMS). Meanwhile, single crystal X-ray diffraction showed the existence of intermolecular N···O hydrogen bonds, which affected the thermal stabilities of corresponding compounds by the support of Thermalgravimetric Analysis (TGA) curves. The steady-state UV-vis absorption peaks of synthetic compounds 1–6 appeared in the range of 220–380 nm. Fluorescence emission spectra showed peaks in the range of 290–420 nm. Meanwhile, deep-blue or violet-blue emissions for 2, 4, and 5 in THF under excitations of 254 nm and 365 nm, respectively, were observed at room temperature in air. Furthermore, Differential pulse voltammetry (DPV) and cyclic voltammogram CV were conducted within −1.5–+1.5 V to show quasi-reversible behavior for conjugated compounds and irreversible behavior for less conjugated ones.

Residual Hydrogen Determination in Perfluoropolyalkylethers Using Fourier Transform Infrared and Proton Nuclear Magnetic Resonance Spectroscopies

1995 ◽  
Vol 49 (10) ◽  
pp. 1474-1477 ◽  
Author(s):  
Jim Liang ◽  
Mark Roselius ◽  
David W. Johnson
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Fourier Transform ◽  
Magnetic Resonance ◽  
Fourier Transform Infrared ◽  
Proton Nuclear Magnetic Resonance ◽  
Linear Calibration ◽  
Standard Samples ◽  
Residual Hydrogen ◽  
Ft Ir ◽  
Nuclear Magnetic

The residual hydrogen content of several perfluoropolyalkylether base fluids has been determined with the use of proton nuclear magnetic resonance (NMR) and Fourier transform infrared (FT-IR) spectroscopies. The analysis of standard samples gives a linear calibration curve for hydrogen concentrations between 0.5 and 500 ppm for both FT-IR and NMR. The two methods have similar detection limits of about 1 ppm. Analysis of identical samples of Krytox 143 AC and Krytox 143 AZ by both methods gives results which are in excellent agreement. The two methods also provide information about the chemical environment in which the hydrogen is located. In both of the Krytox samples, the hydrogen is located in CFH groups within the polymer chain.

A novel carborane-containing ceramic precursor: Synthesis, characterization, and ceramic conversion mechanism

2018 ◽  
Vol 31 (6) ◽  
pp. 694-706 ◽  
Author(s):  
Dejin Tong ◽  
Haipeng Wang ◽  
Lei Chen ◽  
Lei Wang ◽  
Zhanxiong Li
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Oxidative Stability ◽  
Energy Demand ◽  
Proton Nuclear Magnetic Resonance ◽  
Gas Chromatography Mass Spectrometry ◽  
Linear Polymers ◽  
Model Free ◽  
Ft Ir ◽  
Nuclear Magnetic

Linear carborane-carbosilane-phenylacetylene polymers have been synthesized as precursors for ceramic and characterized by Fourier transform infrared (FT-IR), proton nuclear magnetic resonance (1H-NMR), and carbon-nuclear magnetic resonance (13C-NMR). Novel linear polymers have the advantage of being extremely easy to process and convert into ceramics, since they are either viscous liquids or low melting solids at room temperature and are soluble in most organic solvents. Ceramic conversion reaction of the polymers was studied, and the conversion mechanism using thermogravimetric analyzer, FT-IR, and pyrolysis-gas chromatography-mass spectrometry was proposed. During the early heating period in the mechanism, the precursor polymer is cured and oligomer is formed. Then the degradation of oligomer takes place at higher temperatures with the weak bond cleaved and cross-linked simultaneously. Ceramic yield of the polymer after heating up to 1000°C in nitrogen (N2) was 77.6%. The derived ceramics exhibit excellent thermal and thermo-oxidative stability, whose 5% mass loss temperature was identified to be 650°C in N2 and 665°C in air, respectively. Boron appears to be the key element to achieve the outstanding thermo-oxidative stability. The relevant kinetic data were obtained by two kinds of model-free-kinetic algorithms, differential Friedman and integral Kissinger–Akahira–Sunose. These two methods were combined to give the energy profile, which has been identified to be a function of the transformation degree ( α), since the energy demand at each degradation stage is different depending on α.

scholarly journals Yield and Selectivity Improvement in the Synthesis of Carbonated Linseed Oil by Catalytic Conversion of Carbon Dioxide

Polymers ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 852
Author(s):  
David Alejandro González Martínez ◽  
Enrique Vigueras Santiago ◽  
Susana Hernández López
Keyword(s):  
Carbon Dioxide ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
13C Nmr ◽  
Catalyst Concentration ◽  
Linseed Oil ◽  
Proton Nuclear Magnetic Resonance ◽  
Ft Ir ◽  
Epoxidized Linseed Oil ◽  
Nuclear Magnetic

Carbonation of epoxidized linseed oil (CELO) containing five-membered cyclic carbonate (CC5) groups has been optimized to 95% by reacting epoxidized linseed oil (ELO) with carbon dioxide (CO2) and tetrabutylammonium bromide (TBAB) as catalysts. The effect of reaction variables (temperature, CO2 pressure, and catalyst concentration) on the reaction parameters (conversion, carbonation and selectivity) in an autoclave system was investigated. The reactions were monitored, and the products were characterized by Fourier Transform Infrared Spectroscopy (FT-IR), carbon-13 nuclear magnetic resonance (13C-NMR) and proton nuclear magnetic resonance (1H-NMR) spectroscopies. The results showed that when carrying out the reaction at high temperature (from 90 °C to 120 °C) and CO2 pressure (60–120 psi), the reaction’s conversion improves; however, the selectivity of the reaction decreases due to the promotion of side reactions. Regarding the catalyst, increasing the TBAB concentration from 2.0 to 5.0 w/w% favors selectivity. The presence of a secondary mechanism is based on the formation of a carboxylate ion, which was formed due to the interaction of CO2 with the catalyst and was demonstrated through 13C-NMR and FT-IR. The combination of these factors makes it possible to obtain the largest conversion (96%), carbonation (95%), and selectivity (99%) values reported until now, which are obtained at low temperature (90 °C), low pressure (60 psi) and high catalyst concentration (5.0% TBAB).

The regioselective catalyst-free synthesis of bis-quinoxalines and bis-pyrido[2,3-b]pyrazines by double condensation of 1,4-phenylene-bis-glyoxal with 1,2-diamines

2018 ◽  
Vol 24 (4) ◽  
pp. 193-196 ◽  
Author(s):  
Mehdi Ahmadi Sabegh ◽  
Jabbar Khalafy
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
New Products ◽  
Proton Nuclear Magnetic Resonance ◽  
Efficient Synthesis ◽  
H Nmr ◽  
Ft Ir ◽  
C Nmr ◽  
Nuclear Magnetic

AbstractThe oxidation of 1,4-diacetylbenzene using several oxidizing agents gave 1,4-phenylene-bis-glyoxal in 61–85% yields. A convenient and efficient synthesis of bis-quinoxaline and bis-pyrido[2,3-b]pyrazine derivatives involves the double condensation of 1,2-diamines with 1,4-phenylene-bis-glyoxal in ethanol under reflux conditions. The structures of the new products were defined by proton nuclear magnetic resonance (1H NMR), carbon-13 nuclear magnetic resonance (13C NMR), Fourier-transform infrared spectroscopy (FT-IR) and mass spectrometry (MS).

scholarly journals Design, synthesis and anticancer activity evaluation of aziridine-1,2,3-triazole hybrid derivatives

2018 ◽  
Vol 24 (2) ◽  
pp. 109-112 ◽  
Author(s):  
Hong-Ru Dong ◽  
Jian-Guo Wu
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Proton Nuclear Magnetic Resonance ◽  
Human Leukemia ◽  
Anticancer Activities ◽  
One Pot ◽  
Design Synthesis ◽  
H Nmr ◽  
Highly Active ◽  
Nuclear Magnetic

AbstractNew 1-aryl-4-[(aziridine-1-yl)diarylmethyl]-5-methyl-1H-1,2,3-triazole derivatives7a–iwere synthesized by a one-pot reaction of diaryl-(1-aryl-5-methyl-1H-1,2,3-triazol-4-yl)methanols6a–iderived from 1-aryl-5-methyl-1H-1,2,3-triazole-4-carboxylic acids4a–c. Structures of compounds7a–iwere confirmed by analysis of proton nuclear magnetic resonance (1H NMR) and carbon-13 nuclear magnetic resonance (13C NMR), mass spectrometry (MS) and infrared (IR) data. The structure of compound7fwas studied by X-ray diffraction analysis. The anticancer activities of compounds7a–iagainst human leukemia HL-60 cells and human hepatoma G2 cells were evaluated. Some of the compounds are highly active.

scholarly journals Synthesis of (2Z)-4,6-Diphenyl-N-((2-(Piperidin-1-yl)Ethyl]-2H-1,3-Thiazin-2-Imino Hydrochloride and its Antimicrobial Activities

2019 ◽  
pp. 1-9
Author(s):  
Oluwaseyi Bukky Ovonramwen ◽  
Bodunde Joseph Owolabi ◽  
Amowie Philip Oviawe
Keyword(s):  
Staphylococcus Aureus ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Antimicrobial Activities ◽  
Proton Nuclear Magnetic Resonance ◽  
Methicillin Resistant ◽  
Golden Yellow ◽  
Ft Ir ◽  
Nuclear Magnetic

Aim: The study aims to synthesize, characterize, and screen (2Z)-4,6-diphenyl-N-((2-(piperidin-1-yl)ethyl]-2H-1,3-thiazin-2-imino hydrochloride for microbial activities. Methodology: A (2Z)-4,6-diphenyl-N-((2-(piperidin-1-yl)ethyl]-2H-1,3-thiazin-2-imino hydrochloride was synthesized via two-steps reaction from chalcone using acetophenone and benzaldehyde, further cyclized with thiourea and later N-alkylated with 1-(2-chloroethyl)piperidine hydrochloride, its purity was tested by thin-layer chromatography (TLC) and characterized by Fourier transform infrared spectroscopy (FT-IR), proton nuclear magnetic resonance (NMR) and nuclear magnetic resonance (13C-NMR) and screened against Pseudomonas aeruginosa, Escherichia coli, Bacillus subtilis, methicillin-susceptible Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, and Candida albicans using the standard microbiological method. Results: A golden yellow needle-like crystals (2Z)-4,6-diphenyl-N-((2-(piperidin-1-yl)ethyl]-2H-1,3-thiazin-2-imininium hydrochloride with Rf, 7 EtOAc: 3 Pet (0.75) and MP, 285-287oC was synthesized and the in vitro antimicrobial study of the compound exhibited moderate activities in comparison with standard ciprofloxacin and itraconazole. Conclusion: A new (2Z)-4,6-Diphenyl-N-((2-(piperidin-1-yl)ethyl]-2H-1,3-thiazin-2-imininium hydrochloride was synthesized using Claisen-Schmidt condensation, Michael addition and N-alkylation shows moderate antimicrobial activities against E. coli, B. subtilis, methicillin-susceptible S. aureus, methicillin-resistant S. aureus and C. albicans.

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