scholarly journals Detection and Control of Dermatophytosis in Wild European Hedgehogs (Erinaceus europaeus) Admitted to a French Wildlife Rehabilitation Centre

2021 ◽  
Vol 7 (2) ◽  
pp. 74
Author(s):  
Cécile Le Barzic ◽  
Adela Cmokova ◽  
Chloé Denaes ◽  
Pascal Arné ◽  
Vit Hubka ◽  
...  
Keyword(s):  
Trichophyton Mentagrophytes ◽  
Skin Lesions ◽  
Fungal Culture ◽  
Prevention Measures ◽  
Rehabilitation Centre ◽  
Erinaceus Europaeus ◽  
Asymptomatic Carriers ◽  
Wildlife Rehabilitation ◽  
Trichophyton Erinacei ◽  
And Control

The rising number of European hedgehogs (Erinaceus europaeus) admitted every year to wildlife rehabilitation centres might be a source of concern to animal and public health since transmissible diseases, such as dermatophytosis, can be easily disseminated. This study seeks to evaluate the frequency of dermatophyte detection in hedgehogs admitted to a wildlife rehabilitation centre located near Paris, France, and to assess the risk of contamination in the centre in order to adapt prevention measures. A longitudinal cohort study was performed on 412 hedgehogs hosted at the Wildlife Animal Hospital of the Veterinary College of Alfort from January to December 2016. Animals were sampled once a month for fungal culture. Dermatophyte colonies were obtained from 174 out of 686 skin samples (25.4%). Besides Trichophyton erinacei, Trichophyton mentagrophytes and Nannizzia gypsea were also found. Dermatophyte detection seemed to be associated with the presence of skin lesions, while more than one-third of T. erinacei-positive animals were asymptomatic carriers. Healing required several months of treatment with topical and systemic azoles, but dermatophytosis did not seem to reduce the probability of release. Daily disinfection procedures and early detection and treatment of infected and asymptomatic carriers succeeded in limiting dermatophyte transmission between hedgehogs and humans.

scholarly journals European Hedgehogs (Erinaceus europaeus L.) as a Reservoir of Dermatophytes in Poland

2021 ◽  
Author(s):  
Sebastian Gnat ◽  
Dominik Łagowski ◽  
Mariusz Dyląg ◽  
Aneta Nowakiewicz
Keyword(s):  
Human Life ◽  
Primary Source ◽  
Trichophyton Mentagrophytes ◽  
Antifungal Drugs ◽  
Microsporum Canis ◽  
Missense Mutations ◽  
Erinaceus Europaeus ◽  
Trichophyton Erinacei ◽  
Trichophyton Benhamiae ◽  
European Hedgehog

AbstractThe European hedgehog (Erinaceus europaeus Linnaeus) frequently colonises areas located close to human life in cities, as these are more suitable nest sites offering an abundance of food and allowing avoidance of predators. However, urbanisation has a significant impact on the epidemiology of infectious diseases, including dermatophytoses, the primary source of which are wild animals. In this study, we determined the spectrum of dermatophytes isolated from the European hedgehog and assessed their susceptibility profile to antifungal drugs. Symptomatic and asymptomatic dermatophyte infections were observed in 7.7% and 8% of the 182 examined free-living hedgehogs, respectively. In the pool of the isolated dermatophyte strains, Trichophyton erinacei was dominant (29.9%), followed by Trichophyton mentagrophytes (17.9%), Trichophyton benhamiae (13.4%), Nannizzia gypsea (11.9%), Microsporum canis (10.4%), Nannizzia nana (7.5%), Paraphyton cookei (6.0%), and Nannizzia fulva (3.0%). Susceptibility tests revealed the highest activity of luliconazole and the lowest of activity fluconazole among the azole drugs applied. Although terbinafine generally exhibited high efficacy, two Trichophyton mentagrophytes isolates showed resistance to this drug (MIC = 2 µg/ml) resulting from missense mutations in the SQLE gene corresponding to the amino acid substitution Leu393Phe. Summarising, our study has also revealed that such wildlife animals as hedgehogs can be a reservoir of pathogenic human dermatophytes, including harmful strains resistant to commonly used antifungal drugs. Graphical Abstract

scholarly journals OSTEOMYELITIS ON THE CERVICAL VERTEBRAS OF A FREE-LIVING EUROPEAN HEDGEHOG (Erinaceus europaeus) BY Paeniclostridium sordellii

2021 ◽  
Vol 58 (3) ◽  
Author(s):  
Andreia Garcês ◽  
Vanessa Soeiro ◽  
Sara Lóio ◽  
Filipe Silva ◽  
Isabel Pires
Keyword(s):  
Body Condition ◽  
Adult Female ◽  
Post Mortem ◽  
Rehabilitation Centre ◽  
Erinaceus Europaeus ◽  
Free Living ◽  
Wildlife Rehabilitation ◽  
European Hedgehog ◽  
First Time

A free-living European hedgehog (Erinaceus europaeus) adult female was admitted to the Wildlife Rehabilitation Centre of Parque Biológico de Gaia (Portugal), with severe breathing distress and poor body condition. Its neck was displaced 60 degrees caudally. During the post- mortem exam, an abscess in the cervical vertebras was observed. Paeniclostridium sordellii was the agent isolated from the purulent exudate that was removed from the lesion. This is the first reported case of P. sordellii associated osteomyelitis on the cervical vertebras, and the first time that this pathology is describe in this specie associated with this agent.Key words: Erinaceus europaeus; Portugal; Paeniclostridium sordellii; osteomyelitisOSTEOMIELITIS VRATNIH VRETENC PRI PROSTOŽIVEČM EVROPSKEM JEŽU (Erinaceus europaeus), POVZROČEN Z BAKTERIJO Paeniclostridium sordelliiIzvleček: Prosto živeča odrasla samica evropskega ježa (Erinaceus europaeus) je bila sprejeta v Center za rehabilitacijo divjih živali Parque Biológico de Gaia (Portugalska) s hudo dihalno stisko in slabim telesnim stanjem. Njen vrat je bil premaknjen kavdalno za 60 stopinj. Med sekcijo po smrti so opazili absces na vratnih vretencih. Iz gnojnega eksudata lezije je bila izolirana bakteerija Paeniclostridium sordellii. V članku poročamo o prvem zabeleženem primeru osteomielitisa, povezanega s P. sordellii, na vratnih vretencih in o prvem primeru opisa tovrstne patologije pri evropskem ježu, povezani s tem povzročiteljem.Ključne besede: Erinaceus europaeus; Portugalska; Paeniclostridium sordellii; osteomielitis

scholarly journals Dermatophytosis caused by Trichophyton mentagrophytes var. erinacei in a dog: a case report

2014 ◽  
Vol 59 (No. 7) ◽  
pp. 349-351 ◽  
Author(s):  
A. Kurtdede ◽  
AE Haydardedeoglu ◽  
H. Alihosseini ◽  
EC Colakoglu
Keyword(s):  
Trichophyton Mentagrophytes ◽  
Skin Lesions ◽  
Fungal Culture ◽  
Indirect Contact ◽  
Blood Smears ◽  
Fungicidal Treatment ◽  
Mongrel Dog ◽  
History Of ◽  
Oral Itraconazole ◽  
Peripheral Blood Smears

Trichophyton mentagrophytes var. erinacei is rarely isolated from dogs with dermatophytosis. It is a zoophilic dermatophyte transmitted by hedgehogs and, in contrast to other dermatophyte species, is characterised by a severe suppurative and inflammatory response known as kerion. A 5-year-old male mongrel dog was referred to the Veterinary Teaching Hospital with a 2-week history of a localised pruritic and suppurative alopecic lesion on the scrotum. Routine blood tests, peripheral blood smears, multiple skin scrapings and bacteriological culture did not reveal any abnormalities. However, Trichophyton mentagrophytes var. erinacei was isolated from a fungal culture. The presence of hedgehogs around the daily walking areas of the dog suggested the possibility of direct or indirect contact of the dog with hedgehogs. Fungicidal treatment was implemented with oral itraconazole (5 mg/kg once daily) and topical application of clotrimazole (twice daily) for a month. The scrotal lesion healed completely and hair grew back within a month. No recurrence occurred during a 4 month follow-up. T. mentagrophytes var. erinacei should be included in the differential diagnosis of suppurative scrotal skin lesions of dogs, which have come into possible contact with hedgehogs.

scholarly journals Outcomes, Mortality Causes, and Pathological Findings in European Hedgehogs (Erinaceus europeus, Linnaeus 1758): A Seventeen Year Retrospective Analysis in the North of Portugal

Animals ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 1305
Author(s):  
Andreia Garcês ◽  
Vanessa Soeiro ◽  
Sara Lóio ◽  
Roberto Sargo ◽  
Luís Sousa ◽  
...  
Keyword(s):  
Causes Of Death ◽  
Unknown Origin ◽  
Organ Damage ◽  
Skin Lesions ◽  
Rehabilitation Centre ◽  
Rehabilitation Centers ◽  
The North ◽  
Wildlife Rehabilitation ◽  
Mortality Causes ◽  
The University

This study aimed to analyze the admission causes, outcomes, primary causes of death, and main lesions observed in the post mortem examinations of Western European hedgehogs, Erinaceus europaeus (Linnaeus, 1758), in the north of Portugal. The data were obtained by consulting the records from the two main wildlife rehabilitation centers located in the north of Portugal (Wildlife Rehabilitation Centre of Parque Biologico de Gaia and the Wildlife Rehabilitation Centre of the University of Trás-os-Montes and Alto Douro). Over 17 years (2002–2019) a total of 740 animals were admitted. Most of the animals were juveniles, with the highest number of admissions occurring during summer (36.8%) and spring (33.2%). The main reasons for admission were debilitation (30.7%) and random finds (28.4%). Of the total number of individuals admitted to these centers, 66.6% were successfully released back into the wild. The most relevant causes of death were trauma of unknown origin (32.7%), nontrauma causes of unknown origin (26.6%), and nutritional disorders (20.2%). The main lesions observed were related to trauma, including skeletal and skin lesions (fractures, hemorrhages, wounds) and organ damage, particularly to the lungs and liver. The hedgehog is a highly resilient and adaptable animal. The urban environment has many benefits for hedgehogs, yet the presence of humans can be harmful. In the future, the public needs to become even more involved in the activities of the wildlife centres, which will make a positive difference for these populations.

scholarly journals Research Progress of Desertification and Its Prevention in Mongolia

2021 ◽  
Vol 13 (12) ◽  
pp. 6861
Author(s):  
Xiya Liang ◽  
Pengfei Li ◽  
Juanle Wang ◽  
Faith Ka Shun Chan ◽  
Chuluun Togtokh ◽  
...  
Keyword(s):  
Model Development ◽  
Mitigation Strategies ◽  
Research Progress ◽  
Prevention Measures ◽  
Interdisciplinary Approaches ◽  
The World ◽  
Impacting Factors ◽  
Decoupling Analysis ◽  
And Control ◽  
The Relationship

Mongolia is a globally crucial region that has been suffering from land desertification. However, current understanding on Mongolia’s desertification is limited, constraining the desertification control and sustainable development in Mongolia and even other parts of the world. This paper studied spatiotemporal patterns, driving factors, mitigation strategies, and research methods of desertification in Mongolia through an extensive review of literature. Results showed that: (i) remote sensing monitoring of desertification in Mongolia has been subject to a relatively low spatial resolution and considerable time delay, and thus high-resolution and timely data are needed to perform a more precise and timely study; (ii) the contribution of desertification impacting factors has not been quantitatively assessed, and a decoupling analysis is desirable to quantify the contribution of factors in different regions of Mongolia; (iii) existing desertification prevention measures should be strengthened in the future. In particular, the relationship between grassland changes and husbandry development needs to be considered during the development of desertification prevention measures; (iv) the multi-method study (particularly interdisciplinary approaches) and desertification model development should be enhanced to facilitate an in-depth desertification research in Mongolia. This study provides a useful reference for desertification research and control in Mongolia and other regions of the world.

scholarly journals Cutaneous anthrax outbreak associated with handling dead animals, Rhino Camp sub-county: Arua District, Uganda, January–May 2018

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Vivian Ntono ◽  
Daniel Eurien ◽  
Lilian Bulage ◽  
Daniel Kadobera ◽  
Julie Harris ◽  
...  
Keyword(s):  
Health Workers ◽  
Clinical Sample ◽  
Health Centre ◽  
Skin Lesions ◽  
Suspected Case ◽  
Prevention Measures ◽  
Multiple Exposures ◽  
Increased Risk ◽  
Control And Prevention ◽  
Cutaneous Anthrax

Abstract Background On 18 January 2018 a 40 year old man presented with skin lesions at Rhino Camp Health Centre. A skin lesion swab was collected on 20 January 2018 and was confirmed by PCR at Uganda Virus Research Institute on 21 January 2018. Subsequently, about 9 persons were reported to have fallen ill after reporting contact with livestock that died suddenly. On 9 February 2018, Arua District notified Uganda Ministry of Health of a confirmed anthrax outbreak among humans in Rhino Camp sub-county. We investigated to determine the scope and mode of transmission and exposures associated with identified anthrax to guide control and prevention measures. Methods We defined a suspected cutaneous anthrax case as onset of skin lesions (e.g., papule, vesicle, or eschar) in a person residing in Rhino Camp sub-county, Arua District from 25 December 2017 to 31 May 2018. A confirmed case was a suspected case with PCR-positivity for Bacillus anthracis from a clinical sample. We identified cases by reviewing medical records at Rhino Camp Health Centre. We also conducted additional case searches in the affected community with support from Community Health Workers. In a retrospective cohort study, we interviewed all members of households in which at least one person had contact with the carcasses of or meat from animals suspected to have died of anthrax. We collected and tested hides of implicated animals using an anthrax rapid diagnostic test. Results We identified 14 case-patients (1 confirmed, 13 suspected); none died. Only males were affected (affected proportion: 12/10,000). Mean age of case-persons was 33 years (SD: 22). The outbreak lasted for 5 months, from January 2018–May 2018, peaking in February. Skinning (risk ratio = 2.7, 95% CI = 1.1–6.7), dissecting (RR = 3.0, 95% CI = 1.2–7.6), and carrying dead animals (RR = 2.7, 95% CI = 1.1–6.7) were associated with increased risk of illness, as were carrying dissected parts of animals (RR = 2.9, 95% CI 1.3–6.5) and preparing and cooking the meat (RR = 2.3, 95% CI 0.9–5.9). We found evidence of animal remains on pastureland. Conclusion Multiple exposures to the hides and meat of animals that died suddenly were associated with this cutaneous anthrax outbreak in Arua District. We recommended public education about safe disposal of carcasses of livestock that die suddenly.

scholarly journals Leishmaniasis: Current Status of Vaccine Development

2001 ◽  
Vol 14 (2) ◽  
pp. 229-243 ◽  
Author(s):  
Emanuela Handman
Keyword(s):  
Dna Sequences ◽  
Vaccine Development ◽  
Development Program ◽  
Skin Lesions ◽  
Mononuclear Phagocytes ◽  
Control Measures ◽  
Host Susceptibility ◽  
Current Status ◽  
Dna Encoding ◽  
And Control

SUMMARY Leishmaniae are obligatory intracellular protozoa in mononuclear phagocytes. They cause a spectrum of diseases, ranging in severity from spontaneously healing skin lesions to fatal visceral disease. Worldwide, there are 2 million new cases each year and 1/10 of the world's population is at risk of infection. To date, there are no vaccines against leishmaniasis and control measures rely on chemotherapy to alleviate disease and on vector control to reduce transmission. However, a major vaccine development program aimed initially at cutaneous leishmaniasis is under way. Studies in animal models and humans are evaluating the potential of genetically modified live attenuated vaccines, as well as a variety of recombinant antigens or the DNA encoding them. The program also focuses on new adjuvants, including cytokines, and delivery systems to target the T helper type 1 immune responses required for the elimination of this intracellular organism. The availability, in the near future, of the DNA sequences of the human and Leishmania genomes will extend the vaccine program. New vaccine candidates such as parasite virulence factors will be identified. Host susceptibility genes will be mapped to allow the vaccine to be targeted to the population most in need of protection.

scholarly journals The Impact of COVID-19 on Pedestrian Flow Patterns in Urban POIs—An Example from Beijing

2021 ◽  
Vol 10 (7) ◽  
pp. 479
Author(s):  
Yihang Li ◽  
Liyan Xu
Keyword(s):  
Prevention And Control ◽  
Control Period ◽  
Flow Patterns ◽  
Control Measures ◽  
Pedestrian Flow ◽  
Prevention Measures ◽  
Government Control ◽  
Functional Categories ◽  
And Control ◽  
The Impact

The COVID-19 pandemic is a major challenge for society as a whole, and analyzing the impact of the spread of the epidemic and government control measures on the travel patterns of urban residents can provide powerful help for city managers to designate top-level epidemic prevention policies and specific epidemic prevention measures. This study investigates whether it is more appropriate to use groups of POIs with similar pedestrian flow patterns as the unit of study rather than functional categories of POIs. In this study, we analyzed the hour-by-hour pedestrian flow data of key locations in Beijing before, during, and after the strict epidemic prevention and control period, and we found that the pedestrian flow patterns differed greatly in different periods by using a composite clustering index; we interpreted the clustering results from two perspectives: groups of pedestrian flow patterns and functional categories. The results show that depending on the specific stage of epidemic prevention and control, the number of unique pedestrian flow patterns decreased from four before the epidemic to two during the strict control stage and then increased to six during the initial resumption of work. The restrictions on movement are correlated with most of the visitations, and the release of restrictions led to an increase in the variety of unique pedestrian flow patterns compared to that in the pre-restriction period, even though the overall number of visitations decreased, indicating that social restrictions led to differences in the flow patterns of POIs and increased social distance.

scholarly journals The Impact of the Direct Participation of Workers on the Rates of Absenteeism in the Spanish Labor Environment

2020 ◽  
Vol 17 (7) ◽  
pp. 2477 ◽  
Author(s):  
Raúl Payá Castiblanque
Keyword(s):  
Multinomial Logistic Regression ◽  
Management Plan ◽  
Risk Prevention ◽  
Prevention Measures ◽  
Direct Participation ◽  
High Level ◽  
And Control ◽  
The Impact ◽  
The Relationship ◽  
Transversal Study

The aim of this research was to study the relationship between the different levels of direct participation of workers (passive, consultative or active-delegated) in risk prevention management with the levels of absenteeism in Spain. To this end, a transversal study was carried out using microdata from the Second European Survey of Companies on New and Emerging Risks (ESENER-2-Spain, 2014) with a master population of 3162 work centres. A multinomial logistic regression model was carried out, with the dependent variable being the levels of absenteeism and the independent variables, the participation indicators and preventive management, calculating the adjusted odds ratio (aOR) between all the independent and control variables, with their corresponding 95% confidence intervals (95% IC). The results obtained showed how the active-delegative participation of workers in the design and adoption of psychosocial risk prevention measures reported 2.33 less probabilities of having a very high or fairly high level of absenteeism (aOR = 0.43; 95%IC:0.27–0.69). However, having documented aspects of preventive management (plan, risk assessment, planning measures) did not have any impact on absenteeism levels, which shows that we can fall into an unrealistic institutional mirage of security with active policies of co-education or co-management being necessary to reduce absenteeism.

scholarly journals Mechanism and Prevention and Control of Mine Earthquake in Thick and Hard Rock Strata considering the Horizontal Stress Evolution of Stope

2021 ◽  
Vol 2021 ◽  
pp. 1-14
Author(s):  
Ming Zhang ◽  
Xuelong Hu ◽  
Hongtao Huang ◽  
Guangyao Chen ◽  
Shan Gao ◽  
...  
Keyword(s):  
Hard Rock ◽  
Design Method ◽  
Horizontal Stress ◽  
Prevention Measures ◽  
Stress Concentrations ◽  
Estimation Model ◽  
Working Face ◽  
Mining Design ◽  
And Control ◽  
Rock Strata

This study investigated the mechanism, prevention measures, and control methods for earthquake disasters typically occurring in mines with thick and hard rock strata. A mine stope with large faults and thick hard rock strata in Hebei Province was taken as the background study object. Then, theoretical analysis and numerical simulation methods were adopted in conjunction with field monitoring to explore how horizontal stress evolves in the thick and hard hanging roofs of such mines, potentially leading to mining earthquakes. Then, based on the obtained results, a mining design method was proposed to reduce the horizontal stress levels of earthquake mitigation. The results showed that, under the control of large faults, semiopen and semiclosed stopes with thick hard rock strata are formed, which cause influentially pressurized and depressurized zones during the evolution of the overburden movements and horizontal stress. It was determined that the stress concentrations mainly originated from the release and transfer of horizontal stress during the rock fractures and movements in the roof areas, which were calculated using a theoretical estimation model. The horizontal stress concentrations formed “counter torques” at both ends of the thick and hard strata, which prevented the support ending due to tensile failures. As a result, the limit spans were increased. This study proposed a mining strategy of using narrow working faces, strip mining processes, and reasonable mining speeds, which could effectively reduce horizontal stress concentrations and consequently prevent and control mining earthquakes. This study’s research results were successfully applied to the mining practices in working face 16103.

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