scholarly journals Underlying Conditions and Clinical Spectrum of Chronic Pulmonary Aspergillosis (CPA): An Experience from a Tertiary Care Hospital in Karachi, Pakistan

2020 ◽  
Vol 6 (2) ◽  
pp. 41 ◽  
Author(s):  
Nousheen Iqbal ◽  
Muhammad Irfan ◽  
Ammar Mushtaq ◽  
Kauser Jabeen
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Allergic Bronchopulmonary Aspergillosis ◽  
Retrospective Chart Review ◽  
Clinical Spectrum ◽  
Care Hospital ◽  
Pulmonary Aspergillosis ◽  
Specific Immunoglobulin ◽  
Chronic Pulmonary Aspergillosis ◽  
Review Study

The incidence of chronic pulmonary aspergillosis (CPA) is especially increasing in high tuberculosis (TB) burden countries. Despite a high estimated CPA burden in Pakistan, actual data on CPA are not available. The aim of the current study is to determine the underlying conditions and clinical spectrum of CPA at a tertiary care hospital in Karachi, Pakistan. This is a retrospective chart review study in patients admitted with CPA from January 2012 to December 2017. A total of 67 patients were identified during the study period. Mean age of CPA patients was 45.9 ± 15 years, 44 (65.7%) were male and 19 (28.4%) had diabetes. The most common type of CPA was simple aspergilloma (49.2%) followed by chronic cavitary pulmonary aspergillosis (CCPA) (44.7%). TB was the underlying cause of CPA in 58 (86.6%) patients followed by bronchiectasis caused by allergic bronchopulmonary aspergillosis (ABPA) 8 (11.9%). Aspergillus flavus was identified in 17 (47.2%), followed by A. fumigatus in 13 (36.1%) CPA patients. Isolation of multiple Aspergillus species was found in 10 (25.6%) patients. Itraconazole was given in 27 (40.3%) patients and a combination therapy of itraconazole and surgery was given in 21 (31.34%) patients. We found aspergilloma and CCPA as the most prevalent forms of CPA in our setting. Further large prospective studies using Aspergillus specific immunoglobulin G (IgG) antibodies testing are required for better understanding of CPA in Pakistan.

scholarly journals Clinical spectrum of melioidosis at a tertiary care hospital in South India

2016 ◽  
Vol 45 ◽  
pp. 470
Author(s):  
S.V.S. Malladi ◽  
L. Vemu ◽  
N.C. Chandra ◽  
M. Shetty ◽  
K.P. Adiraju ◽  
...  
Keyword(s):  
South India ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Clinical Spectrum ◽  
Care Hospital

scholarly journals Clinical spectrum of congenital heart diseases in a tertiary care hospital

2016 ◽  
Vol 4 (12) ◽  
pp. 2114-2119 ◽  
Author(s):  
Dr. Sharja Phuljhele ◽  
◽  
Dr. Shashikant Dewangan ◽  
Dr. Pranali Thombre ◽  
◽  
...  
Keyword(s):  
Congenital Heart ◽  
Tertiary Care Hospital ◽  
Heart Diseases ◽  
Tertiary Care ◽  
Clinical Spectrum ◽  
Congenital Heart Diseases ◽  
Care Hospital

scholarly journals Acute undifferentiated febrile illness in patients presenting to a Tertiary Care Hospital in South India: clinical spectrum and outcome

2016 ◽  
Vol 8 (4) ◽  
pp. 147 ◽  
Author(s):  
KundavaramPaul Prabhakar Abhilash ◽  
JonathanArul Jeevan ◽  
Shubhanker Mitra ◽  
Nirvin Paul ◽  
ThimiriPalani Murugan ◽  
...  
Keyword(s):  
South India ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Febrile Illness ◽  
Clinical Spectrum ◽  
Care Hospital

scholarly journals Vaccination Status and Clinical Spectrum of Children with Pyogenic Meningitis in A Tertiary Care Hospital of Hazara Division, Pakistan

2021 ◽  
Vol 10 (3) ◽  
pp. 145-151
Author(s):  
Bibi Aalia ◽  
Syed Sajid Hussain Shah
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Vaccination Status ◽  
Clinical Spectrum ◽  
P Value ◽  
Care Hospital ◽  
Age Group ◽  
Pyogenic Meningitis ◽  
Neck Stiffness ◽  
Meningeal Irritation

Background: Pyogenic meningitis is one of the serious causes of mortality and morbidity in children. It is more prevalent in third world countries with poor vaccination coverage. This study was done to determine the vaccination status and clinical spectrum of pyogenic meningitis in children presenting to a tertiary care hospital. Methods: This cross-sectional study was carried out from August, 2017 till January, 2020 over 2.5 years. Records of children who got admitted in pediatric B ward, of either gender between ages of 1 month to 14 years diagnosed as case of pyogenic meningitis were included. Records of vaccination status along with signs of meningeal irritation, complications and outcome during hospital stay were documented. Data was analyzed by SPSS 20 and chi square test applied. P value < 0.05 was taken as significant. Results: There were 117 patients, 78 males and 39 females. Age ranged from 1 month to 14 years with mean age of 5.51± 4.19 years. Patients who were vaccinated up to date were 49.6% and 37.6% were not vaccinated at all. Main presenting feature was fever and seizures especially under one year of age. There was significant association between seizures and age group with p value of 0.001. Signs of meningeal irritation (neck stiffness, brudzinski sign, kerning sign) and paradoxical irritability were present in 85 (72.6%) patients mostly above 1 year of age. There was significant association between signs of meningeal irritation and age group (5 years and above) with p value of <0.001. 110 (94%) got discharged and one (0.9%) patient was referred while 6 (5.1%) patients expired. There was significant association between stay duration and vaccination status. (p = 0.018) Conclusion: Fever was the most common presentation and vaccinated children with pyogenic meningitis had shorter stay in hospital.

scholarly journals A Five-Year Retrospective Review of the Clinical Spectrum and Management Pattern of Dacryocystitis in a Tertiary Care Hospital of Coastal Karnataka

2021 ◽  
Vol 8 (16) ◽  
pp. 1035-1040
Author(s):  
Anagha Dinesh ◽  
Sheetal Savur
Keyword(s):  
Retrospective Review ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Clinical Spectrum ◽  
Care Hospital ◽  
Abnormal Finding ◽  
Female Ratio ◽  
Presenting Symptoms ◽  
Chronic Dacryocystitis ◽  
Study Results

BACKGROUND Dacryocystitis is the most common pathology affecting lacrimal drainage system, representing 79 - 87 % of all lesions. This retrospective study was conducted to understand the clinical spectrum and management patterns of dacryocystitis in the past 5 years in a tertiary care hospital of coastal Karnataka. METHODS This is a five-year retrospective review of the case records of patients with dacryocystitis from the year 2015 to 2019. The records were retrieved from the electronic medical record system of the hospital using the International Statistical Classification (ICD) 10 codes. Data retrieved included, demographic profile, clinical history, presenting symptoms, past surgical interventions, examination findings, systemic comorbidities, pattern of management, medical or surgical management and complications if any. 45 cases that had completed medical records were included in the study. RESULTS The mean age of presentation was 49.37 (± 19.59). The condition was more common in females with a male to female ratio of 1:2.5. The condition was almost equal on both sides. 11 (24.44 %) had bilateral involvement. The patients were mostly from coastal areas or dry plains. Most common presentation was chronic dacryocystitis. Aggravated epiphora was the most common symptom (33) 73.3 %. Diabetes mellitus (15) and hypertension (10) were the most common systemic comorbidities. (22) 48.8 % had no comorbidities. The complications seen were (4) 8.9 % fistula, (1) 2.2 % lacrimal abscess, (2) 4.4 % conjunctivitis and (1) 2.2 % preseptal cellulitis. The patients who underwent nasal examination were (31) 68.9 % out of which, 26 had no abnormal finding in the nose. Surgical treatment was performed in 29 (64.4 %) mainly in the form of dacryocystectomy (DCT) 24 (53.3 %) while only 5 (11.1 %) underwent conventional dacryocystorhinostomy (DCR). CONCLUSIONS Chronic dacryocystitis is the most common form of presentation with higher incidence in the females in the fifth decade of life. Epiphora was the commonest symptom. Most patients who underwent a preoperative nasal examination did not have any pathology. DCT was the more commonly performed procedure. KEYWORDS Acute Dacryocystitis, Chronic Dacryocystitis, Dacryocystectomy, Dacryocystorhinostomy, Epiphora

scholarly journals An Evaluation of Clinical Spectrum of Leprosy in and Around a Tertiary Care Hospital in North India

2017 ◽  
Vol 16 (03) ◽  
pp. 43-48
Author(s):  
Dr. Deepti Gangwar ◽  
Dr. Vivek Gupta ◽  
Dr. Sunil Gupta ◽  
Dr. D.K. Jain ◽  
Dr Shashwat Vidyadhar
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Clinical Spectrum ◽  
North India ◽  
Care Hospital
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